Metabolism and Bacterial Pathogenesis

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Publisher : John Wiley & Sons
ISBN 13 : 1683673344
Total Pages : 581 pages
Book Rating : 4.6/5 (836 download)

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Book Synopsis Metabolism and Bacterial Pathogenesis by : Tyrrell Conway

Download or read book Metabolism and Bacterial Pathogenesis written by Tyrrell Conway and published by John Wiley & Sons. This book was released on 2015-09-01 with total page 581 pages. Available in PDF, EPUB and Kindle. Book excerpt: Groundbreaking thinking on how bacterial metabolism is foundational to pathogenesis For too long, bacterial metabolism and bacterial pathogenesis have been studied as separate entities. However, the scientific community is beginning to realize that not only are bacterial nutrient acquisition and utilization essential for pathogenesis, but that interfering with the pathogen-specific metabolic pathways used during infection can regulate virulence factor expression and might lead to effective breakthroughs in a variety of treatments. Editors Paul Cohen and Tyrrell Conway, who pioneered the use of metabolic mutants in competitive colonization assays, an approach now widely used to investigate the nutrition of pathogens in vivo, are uniquely qualified to advance our knowledge of this integrative field of research. They convened a group of contributors who are breaking new ground in understanding how bacterial metabolism is foundational to pathogenesis to share their expert perspectives and outlook for the future. Beginning with overviews, Metabolism and Bacterial Pathogenesis covers a wide range of diseases and both Gram-positive and -negative bacteria that serve as model systems for in vitro and in vivo investigations intracellular, respiratory, and enteric pathogens pathogen-specific nutrient acquisition in hosts mechanisms of host-driven metabolic adaptation by pathogens metabolic regulation of virulence gene expression Useful for specialists in bacterial pathogenesis and specialists in metabolism as well as molecular biologists, physicians, veterinarians, dentists, graduate and undergraduate students, and laboratory technicians, Metabolism and Bacterial Pathogenesis is also essential reading for scientists studying the microbiome.

Metabolism of Bacterial Infection

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Publisher : Springer
ISBN 13 : 9783031468940
Total Pages : 0 pages
Book Rating : 4.4/5 (689 download)

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Book Synopsis Metabolism of Bacterial Infection by : Vijay Soni

Download or read book Metabolism of Bacterial Infection written by Vijay Soni and published by Springer. This book was released on 2024-02-17 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This machine-generated literature overview provides a comprehensive and up-to-date summary of research on the role of bacterial metabolism in the pathogenesis of bacterial infections. It examines various aspects of bacterial metabolism, including metabolic pathways, nutrient acquisition activities, metabolic adaptation, virulence factors, antibiotic resistance, omics approaches, metabolic engineering, and therapeutic approaches. It is intended for students, researchers, and practitioners in the fields of microbiology, infectious disease, and biomedicine. The auto-summaries have been generated by a recursive clustering algorithm via the Dimensions Auto-summarizer by Digital Science handled by Subject Matter Experts and the external editor. The editor of this book selected which SN content should be auto-summarized and decided its order of appearance. Please be aware that the auto-summaries consist of original sentences, but are not representative of its original paper, since we do not show the full length of the publication. Please note that only published SN content is represented here, and that machine-generated books are still at an experimental stage.

Bacterial Metabolism

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Publisher : Springer Science & Business Media
ISBN 13 : 0387961534
Total Pages : 378 pages
Book Rating : 4.3/5 (879 download)

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Book Synopsis Bacterial Metabolism by : Gerhard Gottschalk

Download or read book Bacterial Metabolism written by Gerhard Gottschalk and published by Springer Science & Business Media. This book was released on 1986 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: I am particularly indebted to Joan Macy, Lynne Quandt, Jan Andreesen and Peter Hillmer for reading the manuscript, for their criticisms and their suggestions, and I thank Ute Gnass for typing the manuscript and for her invaluable help with the indexing and with the preparation of the figures. Finally, I am grateful to the publishers for their patience, willing help, and cooperation. G6ttingen, 1978 GERHARD GOTTSCHALK Contents CHAPTER I Nutrition of Bacteria I. Major and Minor Bioelements I II. The Two Basic Mechanisms of ATP Synthesis 4 III. Nutrients as Energy Sources 6 IV. Growth Factor Requirements of Bacteria 9 V. Summary 10 CHAPTER 2 How Escherichia coli Synthesizes ATP during Aerobic Growth on Glucose I. Transport of D-Glucose into the E. coli Cell 13 II. Degradation of Glucose-6-Phosphate to Pyruvate via the Embden-Meyerhof- Parnas (EMP) Pathway 15 III. Oxidative Decarboxylation of Pyruvate to Acetyl-Coenzyme A 18 IV. Oxidation of Acetyl-CoA via the Tricarboxylic Acid Cycle 20 V. The Formation of ATP in the Respiratory Chain 22 VI. Summary 35 CHAPTER 3 Biosynthesis of Escherichia coli Cells from Glucose I. Composition of E. coli Cells 38 II. Assimilation of Ammonia 40 Ill. Assimilatory Reduction of Sulfate 42 IV. Biosynthesis of Amino Acids 43 V. How Pentose Phosphates and NADPH are Formed 55 xii Contents VI. Ribonucleotides and Deoxyribonucleotides 59 VII. Biosynthesis of Lipids 65 VIII. Formation of Carbohydrates 71 IX. Synthesis of Polymers 73 X. The Requirement for an Anaplerotic Sequence 92 XI.

Bacterial Metabolism

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Publisher : Academic Press
ISBN 13 : 1483272745
Total Pages : 501 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Bacterial Metabolism by : H. W. Doelle

Download or read book Bacterial Metabolism written by H. W. Doelle and published by Academic Press. This book was released on 2014-06-28 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bacterial Metabolism focuses on metabolic events that occur in microorganisms, as well as photosynthesis, oxidation, polysaccharide formation, and homofermentation. The book first discusses the thermodynamics of biological reactions, photosynthesis and photometabolism, and chemosynthesis. Free energy, photosynthesis, enzymes, and terminology in bacterial metabolism are elaborated. The manuscript then examines acetic acid bacteria and lactic acid bacteria. Discussions focus on lactate, ethanol, glucose, and glycerol metabolism, glycol oxidation, homofermentation, polysaccharide formation, and electron transport systems. The publication takes a look at pseudomonadaceae and nitrogen metabolism as an energy source for anaerobic microorganisms. Topics include metabolism of pairs of amino acids, single amino acid metabolism, oxidation of glycolate and malonate, and oxygenases. The book is a dependable source of information for readers interested in bacterial metabolism.

Bacterial Physiology and Metabolism

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Publisher : Academic Press
ISBN 13 : 1483261387
Total Pages : 456 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Bacterial Physiology and Metabolism by : J. R. Sokatch

Download or read book Bacterial Physiology and Metabolism written by J. R. Sokatch and published by Academic Press. This book was released on 2014-06-28 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bacterial Physiology and Metabolism focuses on research on bacteria, as well as metabolism of carbohydrates, fermentation, and oxidation of acids. The book first offers information on nutrition and growth of bacterial cultures, including requirements for growth, nutritional classification of bacteria, measurement of bacterial growth, and synchronous growth of bacterial cultures. The manuscript then considers the chemical composition of bacteria, oligosaccharide catabolism, and transport of sugars. The publication takes a look at the fermentation of sugars and aerobic metabolism of carbohydrates. Discussions focus on Embden-Meyerhof fermentations, miscellaneous pathways, and hexose, pentose, polyol, and hexuronic acid oxidation. The text also elaborates on oxidation of organic acids, electron transport, oxidation of hydrocarbons, and protein and amino acid catabolism. The text is a dependable reference for readers interested in bacterial physiology and metabolism.

Molecular Biology of The Cell

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Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of The Cell by : Bruce Alberts

Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Fundamentals of Bacterial Physiology and Metabolism

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Publisher : Springer Nature
ISBN 13 : 9811607230
Total Pages : 670 pages
Book Rating : 4.8/5 (116 download)

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Book Synopsis Fundamentals of Bacterial Physiology and Metabolism by : Rani Gupta

Download or read book Fundamentals of Bacterial Physiology and Metabolism written by Rani Gupta and published by Springer Nature. This book was released on 2021-04-20 with total page 670 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides useful information on microbial physiology and metabolism. The key aspects covered are prokaryotic diversity, growth physiology, basic metabolic pathways and their regulation, metabolic diversity with details of various unique pathways. Another focus area is stress physiology with details on varying environmental stresses, signal transduction, adaptation and survival. For instructional purposes, the book provides case studies, interesting facts, techniques etc. which help in showcasing the inter-disciplinary nature and bridge the gap between various aspects of applied microbiology.

What You Need to Know about Infectious Disease

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (112 download)

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Book Synopsis What You Need to Know about Infectious Disease by : Madeline Drexler

Download or read book What You Need to Know about Infectious Disease written by Madeline Drexler and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Microbial Metabolism In The Digestive Tract

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Publisher : CRC Press
ISBN 13 : 1351091441
Total Pages : 408 pages
Book Rating : 4.3/5 (51 download)

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Book Synopsis Microbial Metabolism In The Digestive Tract by : M. J. Hill

Download or read book Microbial Metabolism In The Digestive Tract written by M. J. Hill and published by CRC Press. This book was released on 2018-02-01 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book an attempt has been made to give an update on the flora of the human digestive tract and its role in disease. This is a subject that has implications in many disciplines and therefore is aimed at not only microbiologists, but also clinicians, dentists, medical researchers, biochemists, and toxicologists who have a background knowledge of bacteriology but are not necessarily directly involved in research into the metabolic actions of gut bacteria.

Bacterial Metabolism

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Publisher :
ISBN 13 : 9781681179896
Total Pages : 377 pages
Book Rating : 4.1/5 (798 download)

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Book Synopsis Bacterial Metabolism by : Stephanie M. Amato

Download or read book Bacterial Metabolism written by Stephanie M. Amato and published by . This book was released on 2018-06 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolism refers to all the biochemical reactions that take place in a cell or organism. The study of bacterial metabolism focuses on the chemical diversity of substrate oxidations and dissimilation reactions, which normally function in bacteria to generate energy. The role of metabolism in the bacterial response to antibiotics has recently garnered interest because of a rapid rise in antibiotic resistance, a clear link between metabolic function and cell viability, and the lack of novel targets for hard-to-treat infections. Also within the scope of bacterial metabolism is the study of the uptake and utilization of the inorganic or organic compounds required for growth and maintenance of a cellular steady state (assimilation reactions). Genome-scale metabolic models bridge the gap between genome-derived biochemical information and metabolic phenotypes in a principled manner, providing a solid interpretative framework for experimental data related to metabolic states, and enabling simple in silico experiments with whole-cell metabolism.This book entitled "Bacterial Metabolism" presents cutting-edge research and reviews on how bacterial and archaeal structure lead to function, how metabolic processes are regulated, how microbes respond to environmental stressors, and how microbes can be manipulated to enhance their growth or the production of desired products. It also summarises the current knowledge of the bacterial isolates capable of anaerobic mineralization of hydrocarbons, and of the biochemistry and molecular biology of enzymes involved in the catabolic pathways of some of these substrates. Several alkylbenzenes, alkanes or alkenes are anaerobically utilized as substrates by several species of denitrifying, ferric iron-reducing and sulfate-reducing bacteria. The book will be of valued for students, researchers as well as for practitioners dealing with the subject.

Bacterial Metabolism

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Publisher : MIT Press (MA)
ISBN 13 :
Total Pages : 424 pages
Book Rating : 4.:/5 (44 download)

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Book Synopsis Bacterial Metabolism by : Marjory Stephenson

Download or read book Bacterial Metabolism written by Marjory Stephenson and published by MIT Press (MA). This book was released on 1966 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first publication of this book may be said to have marked the formal institution of the study of the biochemistry of bacteria as individual, isolated organisms, and its subsequent editions have reviewed the progress in this area. Bacterial Metabolism is, in effect, Marjory Stephenson's lifelong record book of her results: first issued in 1929, it was fully updated for the second edition of 1939, and again for the present edition which first appeared in 1949.

Metabolism of Human Diseases

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Publisher : Springer
ISBN 13 : 9783709107140
Total Pages : 0 pages
Book Rating : 4.1/5 (71 download)

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Book Synopsis Metabolism of Human Diseases by : Eckhard Lammert

Download or read book Metabolism of Human Diseases written by Eckhard Lammert and published by Springer. This book was released on 2014-06-24 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Metabolism of Human Diseases” examines the physiology of key organs (e.g. brain, eye, lung, heart, blood vessels, blood, immune system, gastrointestinal tract, pancreas, liver, fat tissue, kidney, reproductive system, teeth, bone and joints) and how defective metabolism and signaling pathways within these organs contribute to common human diseases. The latter include depression, schizophrenia, epilepsy, Parkinson's disease, Alzheimer's disease, migraine, multiple sclerosis, Down syndrome, macular degeneration, glaucoma, asthma, COPD, pneumonia, atherosclerotic heart disease, heart failure, stroke, varicose veins, Sickle cell disease, hyperlipidemia, fever, sepsis, allergies, peptic ulcer, gastroenteritis, lactose intolerance, colon cancer, diabetes, cirrhosis, metabolic syndrome, hypertension, chronic kidney disease, gout, urinary tract infections, kidney stones, dental caries, osteoporosis, osteoarthritis, rheumatoid arthritis, breast cancer and prostate cancer. The book also describes commonly used drugs and explains their molecular targets. It provides the first comprehensive and detailed summary of the metabolism of individual organs and their physiological and pathological functioning. Thus it serves as a useful supplement to previous textbooks of human physiology. “Metabolism of Human Diseases” is a must-have, state-of-the-art textbook written by International experts for graduate students, postdocs and scientists in metabolic research, biochemistry, physiology and pharmacy as well as for physicians interested in molecular mechanisms underlying common human diseases.

Bacterial Pathogenesis

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Publisher : Academic Press
ISBN 13 : 0080860567
Total Pages : 643 pages
Book Rating : 4.0/5 (88 download)

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Book Synopsis Bacterial Pathogenesis by :

Download or read book Bacterial Pathogenesis written by and published by Academic Press. This book was released on 1998-07-01 with total page 643 pages. Available in PDF, EPUB and Kindle. Book excerpt: Established almost 30 years ago, Methods in Microbiology is the most prestigious series devoted to techniques and methodology in the field. Now totally revamped, revitalized, with a new format and expanded scope, Methods in Microbiology will continue to provide you with tried and tested, cutting-edge protocols to directly benefit your research. Focuses on the methods most useful for the microbiologist interested in the way in which bacteria cause disease Includes section devoted to 'Approaches to characterising pathogenic mechanisms' by Stanley Falkow Covers safety aspects, detection, identification and speciation Includes techniques for the study of host interactions and reactions in animals and plants Describes biochemical and molecular genetic approaches Essential methods for gene expression and analysis Covers strategies and problems for disease control

The Role of Protein and Amino Acids in Sustaining and Enhancing Performance

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Publisher : National Academies Press
ISBN 13 : 0309172810
Total Pages : 448 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Role of Protein and Amino Acids in Sustaining and Enhancing Performance by : Institute of Medicine

Download or read book The Role of Protein and Amino Acids in Sustaining and Enhancing Performance written by Institute of Medicine and published by National Academies Press. This book was released on 1999-09-15 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is a commonly held belief that athletes, particularly body builders, have greater requirements for dietary protein than sedentary individuals. However, the evidence in support of this contention is controversial. This book is the latest in a series of publications designed to inform both civilian and military scientists and personnel about issues related to nutrition and military service. Among the many other stressors they experience, soldiers face unique nutritional demands during combat. Of particular concern is the role that dietary protein might play in controlling muscle mass and strength, response to injury and infection, and cognitive performance. The first part of the book contains the committee's summary of the workshop, responses to the Army's questions, conclusions, and recommendations. The remainder of the book contains papers contributed by speakers at the workshop on such topics as, the effects of aging and hormones on regulation of muscle mass and function, alterations in protein metabolism due to the stress of injury or infection, the role of individual amino acids, the components of proteins, as neurotransmitters, hormones, and modulators of various physiological processes, and the efficacy and safety considerations associated with dietary supplements aimed at enhancing performance.

Metabolic Interaction in Infection

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Publisher : Springer
ISBN 13 : 3319749323
Total Pages : 478 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis Metabolic Interaction in Infection by : Ricardo Silvestre

Download or read book Metabolic Interaction in Infection written by Ricardo Silvestre and published by Springer. This book was released on 2018-04-06 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on host–pathogen interactions at the metabolic level. It explores the metabolic requirements of the infectious agents, the microbial metabolic pathways that are dedicated to circumvent host immune mechanisms as well as the molecular mechanisms by which pathogens hijack host cell metabolism for their own benefit. Finally, it provides insights on the possible clinical and immunotherapeutic applications, as well as on the available experimental and analytical methods. The contributions break new ground in understanding the metabolic crosstalk between host and pathogen.

Host-adapted metabolism and its regulation in Bacterial Pathogens

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889195384
Total Pages : 178 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis Host-adapted metabolism and its regulation in Bacterial Pathogens by : Thomas Dandekar

Download or read book Host-adapted metabolism and its regulation in Bacterial Pathogens written by Thomas Dandekar and published by Frontiers Media SA. This book was released on 2015-06-17 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pathogens adapt their metabolism rapidly to the host. Our topic covers these phenomenon regarding extracellular and intracellular pathogens as well as general methods to elucidate different metabolic adaptation processes - an essential guide for any scientist wanting to keep abreast of recent developments in infection biology.

Bacterial Metabolism

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Publisher : Springer
ISBN 13 : 9781468404661
Total Pages : 300 pages
Book Rating : 4.4/5 (46 download)

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Book Synopsis Bacterial Metabolism by : G. Gottschalk

Download or read book Bacterial Metabolism written by G. Gottschalk and published by Springer. This book was released on 2012-10-20 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book has been written for students who are taking a course in bacterial metabolism. I hope, however, that scholars will also find it useful either as a help in teaching bacterial metabolism or as a review on the special aspects of metabolism in bacteria. The concept of this book results from my experience in teaching bacterial metabolism. In the first chapters the principal reactions of the energy and biosynthetic metabolism have been discussed using Escherichia coli as a model organism. Then the diversity of aerobic metabolism has been out lined. Following a brief description of the regulation of the level and the activity of enzymes in bacteria the characteristic features of fermentative, chemolithotrophic and phototrophic metabolism have been discussed. Finally, the last chapter has been devoted to nitrogen fixation. Throughout the text I have tried not only to describe metabolic pathways and enzyme reactions but also to elucidate the physiology of the microorganisms which carry out all these metabolic reactions. Two comments regarding the formulas used in this book are necessary.