Metabolic Arrest and the Control of Biological Time

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Author :
Publisher : Harvard University Press
ISBN 13 : 9780674569768
Total Pages : 260 pages
Book Rating : 4.5/5 (697 download)

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Book Synopsis Metabolic Arrest and the Control of Biological Time by : Peter W. Hochachka

Download or read book Metabolic Arrest and the Control of Biological Time written by Peter W. Hochachka and published by Harvard University Press. This book was released on 1987 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Freshwater turtles and goldfish can survive for several days without oxygen, some diving turtles for several months; hibernating animals can exist without food for long periods; others can survive extreme conditions such as desiccation, freezing, and thawing. These creatures are, in effect, self-sustaining life-support systems, with a mysterious ability to regulate their own metabolisms. These capabilities raise important questions, which Hochachka and Guppy explore in this seminal new book. What mechanisms turn down (or off) cell metabolism and other cell functions? How does an animal such as an opossum know when to activate mechanisms for slowing or stopping tissue and organ functions? How does it know when to turn them on again? How extensive is metabolic arrest as a defense against harsh environmental conditions? Can we decipher universal principles of metabolic arrest from available data? The lessons to be learned are of potentially great interest to clinicians, because the authors provide a theoretical framework in which to organize an attack on the all-too-practical problem of protecting tissues against hypoxia. Areas that may be influenced include research on cardiac arrest, strokes, acute renal failure, liver ischemia, lung injury, respiratory defense syndrome, claudication, shock, and organ transplant. Investigation of other metabolic arrest mechanisms may be similarly useful in both clinical and agricultural fields. This is a pioneering book of great use to biomedical/clinical researchers and to biologists, biochemists, and physiologists generally.

Molecular Mechanisms of Metabolic Arrest

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Publisher : Garland Pub
ISBN 13 : 9781859962121
Total Pages : 199 pages
Book Rating : 4.9/5 (621 download)

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Book Synopsis Molecular Mechanisms of Metabolic Arrest by : Kenneth B. Storey

Download or read book Molecular Mechanisms of Metabolic Arrest written by Kenneth B. Storey and published by Garland Pub. This book was released on 2001-01-01 with total page 199 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many organisms can reduce their resting metabolic rate to a state of suspended animation to allow them to survive in adverse environmental conditions. Molecular Mechanisms of Metabolic Arrest focuses on the latest opinions of molecular mechanisms and principles of dormancy regulation, highlighting various new concepts in metabolic rate control. This book will strongly appeal to all molecular and comparative scientists studying organismal responses to environmental stress. It is also of relevance to medical researchers interested in how natural systems of hypometabolism can be applied to relevant problems in medicine.

Understanding the Control of Metabolism

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Author :
Publisher :
ISBN 13 :
Total Pages : 301 pages
Book Rating : 4.:/5 (12 download)

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Book Synopsis Understanding the Control of Metabolism by : David Fell

Download or read book Understanding the Control of Metabolism written by David Fell and published by . This book was released on 1997 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Understanding the control of metabolism

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Author :
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (91 download)

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Book Synopsis Understanding the control of metabolism by : David Fell

Download or read book Understanding the control of metabolism written by David Fell and published by . This book was released on 1996 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Encyclopedia of Ecology

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Publisher : Newnes
ISBN 13 : 008091456X
Total Pages : 4292 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Encyclopedia of Ecology by : Brian D. Fath

Download or read book Encyclopedia of Ecology written by Brian D. Fath and published by Newnes. This book was released on 2014-11-03 with total page 4292 pages. Available in PDF, EPUB and Kindle. Book excerpt: The groundbreaking Encyclopedia of Ecology provides an authoritative and comprehensive coverage of the complete field of ecology, from general to applied. It includes over 500 detailed entries, structured to provide the user with complete coverage of the core knowledge, accessed as intuitively as possible, and heavily cross-referenced. Written by an international team of leading experts, this revolutionary encyclopedia will serve as a one-stop-shop to concise, stand-alone articles to be used as a point of entry for undergraduate students, or as a tool for active researchers looking for the latest information in the field. Entries cover a range of topics, including: Behavioral Ecology Ecological Processes Ecological Modeling Ecological Engineering Ecological Indicators Ecological Informatics Ecosystems Ecotoxicology Evolutionary Ecology General Ecology Global Ecology Human Ecology System Ecology The first reference work to cover all aspects of ecology, from basic to applied Over 500 concise, stand-alone articles are written by prominent leaders in the field Article text is supported by full-color photos, drawings, tables, and other visual material Fully indexed and cross referenced with detailed references for further study Writing level is suited to both the expert and non-expert Available electronically on ScienceDirect shortly upon publication

Time

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Publisher : Profile Books
ISBN 13 : 184765259X
Total Pages : 224 pages
Book Rating : 4.8/5 (476 download)

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Book Synopsis Time by : Eva Hoffman

Download or read book Time written by Eva Hoffman and published by Profile Books. This book was released on 2010-07-09 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Time has always been the great Given, a fact of existence which cannot be denied or wished away; but the character of lived time is changing dramatically. Medical advances extend our longevity, while digital devices compress time into ever briefer units. We can now exist in several time-zones simultaneously, but we suffer from endemic shortages of time. We are working longer hours and blurring the distinctions between labour and leisure. For many, in an inversion of the old adage, time has become more valuable than money. In this look at life's most ineffable element, spanning fields from biology and culture to psychoanalysis and neuroscience, Eva Hoffman asks: are we coming to the end of time as we know it?

Sepsis, An Issue of Critical Care Clinics, E-Book

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 0323566340
Total Pages : pages
Book Rating : 4.3/5 (235 download)

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Book Synopsis Sepsis, An Issue of Critical Care Clinics, E-Book by : Mervyn Singer

Download or read book Sepsis, An Issue of Critical Care Clinics, E-Book written by Mervyn Singer and published by Elsevier Health Sciences. This book was released on 2017-11-27 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Critical Care Clinics, edited by Mervyn singer and Manu Shankar-Hari, includes: Sepsis 3.0 Definitions; Epidemiology and Outcomes; Pathophysiology of sepsis; Pathophysiology of Septic shock; Mechanism of organ dysfunction in sepsis; Endocrine and metabolic alterations in sepsis: challenges and treatments; The immune system in sepsis; Nutrition and Sepsis; Common sense approach to managing sepsis; Biomarkers for sepsis and their use; Personalizing sepsis care; Novel interventions - What’s new and the future; and Long term outcomes following Sepsis.

Cell Chemistry and Physiology: Part I

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Publisher : Elsevier
ISBN 13 : 0080528767
Total Pages : 397 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Cell Chemistry and Physiology: Part I by : Edward Bittar

Download or read book Cell Chemistry and Physiology: Part I written by Edward Bittar and published by Elsevier. This book was released on 1996-01-04 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first of a 4-volume module that is an introduction to the study of cell chemistry and physiology. It is not intended to be encyclopedic in nature but rather a general survey of the subject with an emphasis on those topics that are central to an understanding of cell biology and those that are certain to become of increasing importance in the teaching of modern medicine.We have followed what appeared to as to be the logical divisions of the subject beginning with proteins. Allewell and her colleagues stress the point that proteins fold spontaneously to form complex three-dimensional structures and that some of them unfold with the help of proteins called chaperones. Michaelis-Menten kinetics are shown by Nelsestuen to describe the behaviour of enzymes in the test tube. The formalism is particularly useful in the search for agents of therapeutic value, as exemplified by methotrexate. Uptake by mammalian cells of substrates and their metabolic conversions are discussed by van der Vusse and Reneman. However, both Welch and Savageau expound the view that the cell is not simply a bagful of enzymes. The biologist is urged by Savageau to abandon Michaelis-Menten formalism and apply the Power Law. The biologist is also told that the approach to arriving at a theory of metabolic control would have to be one of successive approximations requiring the use of the computer. Information gained from comparative biochemistry is shown by Storey and Brooks to have shed new light on mechanisms of metabolic rate depression and freeze tolerance, and to be applicable to organ transplantation technology. We are reminded that enzyme adaptation is partly the result of the presence of a hydrating shell of vicinal water that stabilises conformation of the enzyme. Vicinal water, according to Drost-Hausen and Singleton, lies adjacent to most solids and protein interfaces. The kinks or breaks observed in the slope of the Arrhenius plot are attributed to structural changes in vicinal water. Regulation of cell volume is shown by Hempling to involve regulation of cell water. It could be that the osmo-receptor or volume detection system is a protein that links the cytoskeleton to specific K and C1 channels. Additionally, it is interesting that aquaporins, which are water channel-forming membrane proteins, are now known to exist in both renal and extra-renal tissues. One of the renal porins is affected by vasopressin. We then pass on to protein synthesis (Rattan) and other important topics including protein glycosylation (Hounsell), methylation (Clarke), ADP-ribosylation (Pearson) and prenylation (Gelb). Among the four types of lipids attached to membrane proteins are the prenyl groups. Ford and Gross in their chapter on lipobiology drive home the point that there is an accumulation of acyl carnitine and lysophospholipids during myocardial infarction.

Oxidative Stress in Aquatic Ecosystems

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Publisher : John Wiley & Sons
ISBN 13 : 1444345966
Total Pages : 818 pages
Book Rating : 4.4/5 (443 download)

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Book Synopsis Oxidative Stress in Aquatic Ecosystems by : Doris Abele

Download or read book Oxidative Stress in Aquatic Ecosystems written by Doris Abele and published by John Wiley & Sons. This book was released on 2011-11-03 with total page 818 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reactive oxygen species (ROS) are increasingly appreciated as down-stream effectors of cellular damage and dysfunction under natural and anthropogenic stress scenarios in aquatic systems. This comprehensive volume describes oxidative stress phenomena in different climatic zones and groups of organisms, taking into account specific habitat conditions and how they affect susceptibility to ROS damage. A comprehensive and detailed methods section is included which supplies complete protocols for analyzing ROS production, oxidative damage, and antioxidant systems. Methods are also evaluated with respect to applicability and constraints for different types of research. The authors are all internationally recognized experts in particular fields of oxidative stress research. This comprehensive reference volume is essential for students, researchers, and technicians in the field of ROS research, and also contains information useful for veterinarians, environmental health professionals, and decision makers.

Hormones and Metabolism in Insect Stress

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Publisher : CRC Press
ISBN 13 : 1351090135
Total Pages : 285 pages
Book Rating : 4.3/5 (51 download)

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Book Synopsis Hormones and Metabolism in Insect Stress by : Jelisaveta Ivanovic

Download or read book Hormones and Metabolism in Insect Stress written by Jelisaveta Ivanovic and published by CRC Press. This book was released on 2018-01-31 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the effects of both natural (e.g., temperature, humidity, and lack of food) and man-induced stressors (e.g., pollution) on insects. Insect neurohormones and metabolism are emphasized, although all aspects of insect biology are examined. The role of ecdysteroids and juvenile hormones in response to thermal and other stressors is featured, and population studies in insect stress are presented. Entomologists, ecologists, ecophysiologists, physiologists, applied entomologists and others will find Hormones and Metabolism in Insect Stress an important reference resource.

Environmental Project Management

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Publisher : Springer
ISBN 13 : 3319276514
Total Pages : 413 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Environmental Project Management by : Ebenezer A. Sholarin

Download or read book Environmental Project Management written by Ebenezer A. Sholarin and published by Springer. This book was released on 2016-04-22 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a new framework that facilitates the development of more intelligent systems and methods for data analysis and international information sharing, such as the use of satellite imaging and geospatial data to predict changes in weather conditions and shifts in water levels, and to assess the extent of the forest cover remaining on Earth that is visible from space. It brings together the many aspects of science and technology, as well as formula and analytical approaches required for more informed decision-making. It also highlights the vital importance of understanding the technological, economic and social dimensions of environmental projects that have short-term results and long-term impacts. It is unique in that it clearly distinguishes between environmental project management (EnvPM) and green project management (GreenPM), and presents an amalgamation of environmental management and project management concepts, using geospatial methods to form an EnvPM concept. The book sets a benchmark for the professionalism with which environmental projects should be planned, executed, monitored, assessed and delivered. While primarily intended for professionals responsible for the management of environmental projects or interested in improving the overall efficiency of such projects, it is also a useful handbook for managers in the private, public and non-for-profit sectors. It is a valuable resource for students at both undergraduate and master’s levels and an indispensable guide for anyone wanting to develop their skills in modern project management, environmental management and geospatial techniques. ``We are the first generation to feel the impact of climate change, and the last generation that can do something about it.'' US President Obama's address to the United Nations on Climate Change and Global warming (2015) hison: This book provides an in-depth, well-researched and science-based approach to applying key project-management and spatial tools and practices in environmental projects. An important read for leaders considering projects that balance social-economic growth against minimising its ill-effects on Planet Earth. - Todd Hutchison, Global Chairman of Peopleistic group.

Temperature Regulation in Humans and Other Mammals

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Publisher : Springer Science & Business Media
ISBN 13 : 3642594611
Total Pages : 202 pages
Book Rating : 4.6/5 (425 download)

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Book Synopsis Temperature Regulation in Humans and Other Mammals by : Claus Jessen

Download or read book Temperature Regulation in Humans and Other Mammals written by Claus Jessen and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: How do mammals manage to maintain their body temperature within the same narrow range in environments as different as polar regions and hot deserts? This advanced text describes the morphological features and physiological mechanisms by which humans and other mammals maintain their body temperature within a narrow range despite large variations in climatic conditions and internal heat production. Its 19 chapters deal with the physics of heat exchange with the environment, and the autonomic and behavioural mechanisms available to control the loss and production of heat. The neuronal basis of temperature regulation and current concepts of the central nervous interface between temperature signals generated in the body and control mechanisms are examined in detail. This book is of invaluable help for undergraduates, postgraduates, teachers, physicians and scientists.

Oxygen Sensing in Tissues

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Publisher : Springer Science & Business Media
ISBN 13 : 3642834442
Total Pages : 214 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis Oxygen Sensing in Tissues by : Helmut Acker

Download or read book Oxygen Sensing in Tissues written by Helmut Acker and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers a wide biological range of problems regarding oxygen sensing in tissues. Oxygen sensing is defined as a process in which 02 reacts with different cellular components to avoid hypoxic cell damages. Oxygen sensing contributes to auxiliary mechanisms which help bacteria, invertebrates, vertebrates, and mammalians to survive and withstand hypoxic sensations. For the first time, experts from different disciplines have cooperated in examining various biological systems exhibiting this phenomenon.

Genetic Effects on Aging

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Publisher : CRC Press
ISBN 13 : 9780936923314
Total Pages : 612 pages
Book Rating : 4.9/5 (233 download)

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Book Synopsis Genetic Effects on Aging by : David E. Harrison

Download or read book Genetic Effects on Aging written by David E. Harrison and published by CRC Press. This book was released on 1990-08-09 with total page 612 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides background knowledge useful to those setting out to do genetic studies of aging in mammals, and raises vital questions: How many genes are important in mammalian aging? What are the optimal methods for their study? To what degree are patterns of aging, and patterns of growth and development part of the same process? Do patterns of development predict subsequent patterns of growth and aging? Are there a few fundamental aging processes, or does every biological system age? The rapid rate of progress in this field required a new volume with a new approach, based on the combination of classical genetics and the powerful new tools of molecular genetics. Although mammalian systems are emphasized, representatives of the advanced genetic studies in Drosophila and other model systems are included. The purpose is to enrich and stimulate genetic studies of mammalian aging by suggesting and evaluating future possibilities.

Diving Seals and Meditating Yogis

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Publisher : University of Chicago Press
ISBN 13 : 022624671X
Total Pages : 192 pages
Book Rating : 4.2/5 (262 download)

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Book Synopsis Diving Seals and Meditating Yogis by : Robert Elsner

Download or read book Diving Seals and Meditating Yogis written by Robert Elsner and published by University of Chicago Press. This book was released on 2015-04-21 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: Survival in extreme conditions is not about running for cover, or coming up for air, but rather in many instances working within the confines of the environment and instead suppressing bodily function. Yogis do it, seals do it, even sleeping bears do itthat is, alter their physiology in order to survive. This physiology of survival is explored here, including its evolution and varied manifestations across the animal kingdom. In the course of exploration over the years, researchers in comparative physiology have discovered fascinating and unanticipated commonalities. One might not expect to find a common theme relating the physiological reactions of seals, and yogis, and the comparisons extend even further afield, to hibernating animals, infants during birth, near-drowning victims, and clams at low tide. The common threads linking this unlikely mix of animals and situations are shared reactions to unfavorable environments, reactions that include lowering energetic requirements and retreating into states of depressed metabolism. Scrutiny of these diverse examples reveals some suggestive insights into the biology of survival and well-being. Animals in these withdrawn states are less dependent upon their customary levels of oxygen consumption, temporarily lessening their need for that life-sustaining resource. Instead they rely upon temporary strategic retreats of reduced metabolism, later resuming normal activity when conditions become more favorable. These states, and also the regulatory functions, including the neural and endocrine, that integrate to maintain equilibrium in altered environments or in temporarily challenging situations are examined. Breath-hold diving and its inevitable progressive asphyxia, often with cold exposure and swimming exercise that may accompany underwater submergence, comprises an assault on the ordinary homeostatic condition of the animal. These encounters, for which seals and other marine mammals are well adapted (but humans less so) alter resting equilibrium, and entail remarkable physiological orchestration."

Environmental Physiology of Animals

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Publisher : John Wiley & Sons
ISBN 13 : 1444309226
Total Pages : 768 pages
Book Rating : 4.4/5 (443 download)

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Book Synopsis Environmental Physiology of Animals by : Pat Willmer

Download or read book Environmental Physiology of Animals written by Pat Willmer and published by John Wiley & Sons. This book was released on 2009-03-12 with total page 768 pages. Available in PDF, EPUB and Kindle. Book excerpt: The new and updated edition of this accessible text provides a comprehensive overview of the comparative physiology of animals within an environmental context. Includes two brand new chapters on Nerves and Muscles and the Endocrine System. Discusses both comparative systems physiology and environmental physiology. Analyses and integrates problems and adaptations for each kind of environment: marine, seashore and estuary, freshwater, terrestrial and parasitic. Examines mechanisms and responses beyond physiology. Applies an evolutionary perspective to the analysis of environmental adaptation. Provides modern molecular biology insights into the mechanistic basis of adaptation, and takes the level of analysis beyond the cell to the membrane, enzyme and gene. Incorporates more varied material from a wide range of animal types, with less of a focus purely on terrestrial reptiles, birds and mammals and rather more about the spectacularly successful strategies of invertebrates. A companion site for this book with artwork for downloading is available at: www.blackwellpublishing.com/willmer/

Environmental Stressors and Gene Responses

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Publisher : Elsevier
ISBN 13 : 0080531121
Total Pages : 325 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Environmental Stressors and Gene Responses by : J.M. Storey

Download or read book Environmental Stressors and Gene Responses written by J.M. Storey and published by Elsevier. This book was released on 2000-07-31 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell and Molecular Responses to Stress is a new multi-volume book series from Elsevier Science that focuses on how organisms respond at a molecular level to environmental stresses imposed upon them. All organisms deal with variations in multiple environmental factors including temperature, oxygen, salinity, and water availability. Many show amazing tolerances to extreme stress with remarkable biochemical adaptations that allow life to persist under very difficult circumstances. This series explores the molecular mechanisms by which cells and organisms respond to stress, focusing on the variations in metabolic response that allow some cells and organisms to deal with extreme stress, others to endure stress within strict limits, and others to have a very low tolerance for changes in environmental parameters.Articles from within the series highlight the elastic limits of molecular responses in Nature, with examples drawn from animal, plant and bacteria systems.Volume 1, begins by considering some of the roles of environmental stress in determining the geographic distribution of animals and in promoting species divergence and then explores gene expression and metabolic responses to environmental stress with examples of adaptation to high and low temperature, osmotic, anoxia/ischemia, desiccation, high pressure and heavy metal stresses.