Membrane Lipid Signaling in Aging and Age-Related Disease

Download Membrane Lipid Signaling in Aging and Age-Related Disease PDF Online Free

Author :
Publisher : Elsevier
ISBN 13 : 0080522505
Total Pages : 237 pages
Book Rating : 4.0/5 (85 download)

DOWNLOAD NOW!


Book Synopsis Membrane Lipid Signaling in Aging and Age-Related Disease by : M.P. Mattson

Download or read book Membrane Lipid Signaling in Aging and Age-Related Disease written by M.P. Mattson and published by Elsevier. This book was released on 2003-05-06 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: The lipids of cellular membranes not only serve roles in controlling the structure and fluidity of the membrane, but are increasingly recognized for their roles as signalling molecules and modifiers of membrane protein function. Recent studies described in this volume reveal striking changes in membrane lipids during aging and in age-related diseases such as cancer, cardiovascular disease and neurodegenerative disorders. Lipids including inositol phospholipids, cholesterol, sphingolipids and ceramides play important roles in signalling cellular responses to stress and specific stimuli such as growth factors, cytokines and neurotransmitters. One or more of these lipid mediators has been linked to the pathogenesis of age-related diseases. This book provides a comprehensive review of specific membrane lipid mediators and their roles in aging and age-related disease.

Membrane Lipid Signaling in Aging and Age-Related Disease

Download Membrane Lipid Signaling in Aging and Age-Related Disease PDF Online Free

Author :
Publisher : Elsevier Science
ISBN 13 : 9780444512970
Total Pages : 0 pages
Book Rating : 4.5/5 (129 download)

DOWNLOAD NOW!


Book Synopsis Membrane Lipid Signaling in Aging and Age-Related Disease by : M.P. Mattson

Download or read book Membrane Lipid Signaling in Aging and Age-Related Disease written by M.P. Mattson and published by Elsevier Science. This book was released on 2003-05-06 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The lipids of cellular membranes not only serve roles in controlling the structure and fluidity of the membrane, but are increasingly recognized for their roles as signalling molecules and modifiers of membrane protein function. Recent studies described in this volume reveal striking changes in membrane lipids during aging and in age-related diseases such as cancer, cardiovascular disease and neurodegenerative disorders. Lipids including inositol phospholipids, cholesterol, sphingolipids and ceramides play important roles in signalling cellular responses to stress and specific stimuli such as growth factors, cytokines and neurotransmitters. One or more of these lipid mediators has been linked to the pathogenesis of age-related diseases. This book provides a comprehensive review of specific membrane lipid mediators and their roles in aging and age-related disease.

Membrane Lipid Signaling in Aging and Age-Related Disease

Download Membrane Lipid Signaling in Aging and Age-Related Disease PDF Online Free

Author :
Publisher : Elsevier Science
ISBN 13 : 9780444512970
Total Pages : 236 pages
Book Rating : 4.5/5 (129 download)

DOWNLOAD NOW!


Book Synopsis Membrane Lipid Signaling in Aging and Age-Related Disease by : M.P. Mattson

Download or read book Membrane Lipid Signaling in Aging and Age-Related Disease written by M.P. Mattson and published by Elsevier Science. This book was released on 2003-05-20 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: The lipids of cellular membranes not only serve roles in controlling the structure and fluidity of the membrane, but are increasingly recognized for their roles as signalling molecules and modifiers of membrane protein function. Recent studies described in this volume reveal striking changes in membrane lipids during aging and in age-related diseases such as cancer, cardiovascular disease and neurodegenerative disorders. Lipids including inositol phospholipids, cholesterol, sphingolipids and ceramides play important roles in signalling cellular responses to stress and specific stimuli such as growth factors, cytokines and neurotransmitters. One or more of these lipid mediators has been linked to the pathogenesis of age-related diseases. This book provides a comprehensive review of specific membrane lipid mediators and their roles in aging and age-related disease.

Interorganellar Signaling in Age-Related Disease

Download Interorganellar Signaling in Age-Related Disease PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : 292 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!


Book Synopsis Interorganellar Signaling in Age-Related Disease by : M.P. Mattson

Download or read book Interorganellar Signaling in Age-Related Disease written by M.P. Mattson and published by . This book was released on 2001-04-19 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Collectively, the chapters in this work will provide the reader with novel insight into the inter-relationships of the function of different organelles in the sequences of events that lead to cellular dysfunction and degeneration in the aging human population. The chapters are rich in information for cell and molecular biologists pursuing studies of the different diseases covered. In addition, the clinician will find value in understanding mechanisms underlying age-related disease as such an understanding will lead to novel therapeutic approaches for an array of age-related diseases.

Membrane Structure

Download Membrane Structure PDF Online Free

Author :
Publisher : Elsevier
ISBN 13 : 0080860591
Total Pages : 284 pages
Book Rating : 4.0/5 (88 download)

DOWNLOAD NOW!


Book Synopsis Membrane Structure by :

Download or read book Membrane Structure written by and published by Elsevier. This book was released on 1981-01-01 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Membrane Structure

Brain Aging

Download Brain Aging PDF Online Free

Author :
Publisher : CRC Press
ISBN 13 : 9781420005523
Total Pages : 408 pages
Book Rating : 4.0/5 (55 download)

DOWNLOAD NOW!


Book Synopsis Brain Aging by : David R. Riddle

Download or read book Brain Aging written by David R. Riddle and published by CRC Press. This book was released on 2007-04-19 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recognition that aging is not the accumulation of disease, but rather comprises fundamental biological processes that are amenable to experimental study, is the basis for the recent growth of experimental biogerontology. As increasingly sophisticated studies provide greater understanding of what occurs in the aging brain and how these changes occur

Free Radicals and Antioxidant Protocols

Download Free Radicals and Antioxidant Protocols PDF Online Free

Author :
Publisher : Humana Press
ISBN 13 : 9781617796838
Total Pages : 480 pages
Book Rating : 4.7/5 (968 download)

DOWNLOAD NOW!


Book Synopsis Free Radicals and Antioxidant Protocols by : Rao M. Uppu

Download or read book Free Radicals and Antioxidant Protocols written by Rao M. Uppu and published by Humana Press. This book was released on 2012-04-06 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: This cutting-edge and updated book offers methods for the rapid detection of RONs and redox stress. It includes in-depth analysis of natural and synthetic antioxidants, and also of DNA oxidation, oxidative lipidomics, and biomarkers.

Handbook on Immunosenescence

Download Handbook on Immunosenescence PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1402090633
Total Pages : 1693 pages
Book Rating : 4.4/5 (2 download)

DOWNLOAD NOW!


Book Synopsis Handbook on Immunosenescence by : Tamas Fulop

Download or read book Handbook on Immunosenescence written by Tamas Fulop and published by Springer Science & Business Media. This book was released on 2009-02-27 with total page 1693 pages. Available in PDF, EPUB and Kindle. Book excerpt: This authoritative handbook covers all aspects of immunosenescence, with contributions from experts in the research and clinical areas. It examines methods and models for studying immunosenescence; genetics; mechanisms including receptors and signal transduction; clinical relevance in disease states including infections, autoimmunity, cancer, metabolic syndrome, neurodegenerative diseases, frailty and osteoporosis; and much more.

Osteosarcopenia: Bone, Muscle and Fat Interactions

Download Osteosarcopenia: Bone, Muscle and Fat Interactions PDF Online Free

Author :
Publisher : Springer Nature
ISBN 13 : 3030258904
Total Pages : 383 pages
Book Rating : 4.0/5 (32 download)

DOWNLOAD NOW!


Book Synopsis Osteosarcopenia: Bone, Muscle and Fat Interactions by : Gustavo Duque

Download or read book Osteosarcopenia: Bone, Muscle and Fat Interactions written by Gustavo Duque and published by Springer Nature. This book was released on 2019-11-06 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited work presents the most current evidence on osteosarcopenia from bench to bedside, which is expected to facilitate the understanding of this syndrome and to develop preventive and therapeutic strategies. With our aging population, chronic diseases such as osteoporosis and sarcopenia are becoming highly prevalent. Fortunately, our understanding of the bone and muscle interactions has increased in recent years. This has allowed to the coining of the term osteosarcopenia to describe a syndrome in which these two diseases overlap. This overlap between osteoporosis and sarcopenia has major negative effects not only on our older adults but also on health systems worldwide. Readers will find a highly translational approach that starts with a summary of recent discoveries on stem cells biology, muscle and bone interactions – including the role of local bone and muscle fat – followed by comprehensive reviews on myokines (i.e. myostatin), osteokines (i.e. osteocalcin) and adipokines (i.e. interleukins) as major players and determinants of bone and muscle loss with aging. In addition, the role of sex steroids (i.e. estrogens, androgens), and calciotropic hormones (i.e. parathyroid hormone, vitamin D) in the pathogenesis of this syndrome is also reviewed. Moreover, using practical diagnostic and therapeutic tips, this book summarizes the clinical characteristics of osteosarcopenic patients thus facilitating the diagnosis and treatment of this syndrome in clinical practice. Finally, the book presents the case for the Falls and Fractures Clinic as the optimal model of care for this syndrome, aimed to avoid fragmentation and optimize osteosarcopenia care, and simultaneously prevent falls and fractures in older persons. This book offers relevant information on the mechanisms of osteosarcopenia, and a practical guide on how to identify and treat this geriatric syndrome and its adverse outcomes, which are dramatically affecting our aging population. The work is written by leaders in the field and is especially suited not only to any researcher in the musculoskeletal arena but also to medical specialists and allied health professionals involved in the care of older persons.

Sleep and Aging

Download Sleep and Aging PDF Online Free

Author :
Publisher : Elsevier
ISBN 13 : 9780444518767
Total Pages : 212 pages
Book Rating : 4.5/5 (187 download)

DOWNLOAD NOW!


Book Synopsis Sleep and Aging by : Mark P. Mattson

Download or read book Sleep and Aging written by Mark P. Mattson and published by Elsevier. This book was released on 2005-06-20 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sleep and Aging provides a unique and timely collection of review articles that cover the gamut of basic and clinical aspects of sleep and the abnormalities in sleep associated with aging and neurological disorders that occur during aging. From the evolutionary basis of sleep and its normal functions in processes such as learning and memory, to considerations of the roles of sleep abnormalities in neurological disorders such as depression, Alzheimer's and Parkinson's diseases, the chapters are written by experts in the field. Several chapters focus on signalling pathways involved in sleep regulation and abnormalities in sleep, including those activated by serotonin and BDNF. Basic and clinical research on insomnia, sleep apnea and other disorders of sleep, are covered thus providing students and scientists at all levels with a valuable source of information to advance their understanding of this important topic in aging, biology and medicine. The circuits in the brain involved in sleep regulation, their neurochemistry, how they are altered in disorders of sleep and current clinical treatments of various sleep disorders are reviewed. The important role of sleep disturbances in neurodegenerative disorders is described and research in this particular area is leading to a better understanding of the relationships between synaptic plasticity, neuronal degeneration and the clinical manifestations of disorders such as Alzheimer's disease, Parkinson's disease and depression. This book is a must for scientists, as well as non-scientists, who are interested in the neurobiology of aging, sleep and neurodegenerative disorders.

Aging and Age-Related Disorders

Download Aging and Age-Related Disorders PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1607616025
Total Pages : 468 pages
Book Rating : 4.6/5 (76 download)

DOWNLOAD NOW!


Book Synopsis Aging and Age-Related Disorders by : Stephen Bondy

Download or read book Aging and Age-Related Disorders written by Stephen Bondy and published by Springer Science & Business Media. This book was released on 2010-09-02 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: Features that characterize the aging process include the gradual accumulation of cell damage after prolonged exposure to oxidative and inflammatory events over a lifetime. In addition to the accretion of lesions, the intrinsic levels of pro-oxidant and aberrant immune responses are elevated with age. These adverse events are often further enhanced by the chronic and slow progressing diseases that characterize the senescent brain and cardiovascular system. The incidence of some disorders such as Alzheimer's disease and vascular diseases are sufficiently prevalent in the extreme elderly that these disorders can arguably be considered "normal". Aging and Aging-Related Disorders examines the interface between normal and pathological aging, and illustrates how this border can sometimes be diffuse. It explores and illustrates the processes underlying the means by which aging becomes increasingly associated with inappropriate levels of free radical activity and how this can serve as a platform for the progression of age-related diseases. The book provides chapters that examine the interactive relationship between systems in the body that can enhance or sometimes even limit cellular longevity. In addition, specific redox mechanisms in cells are discussed. Another important aspect for aging discussed here is the close relationship between the systems of the body and exposure to environmental influences of oxidative stress that can affect both cellular senescence and a cell’s nuclear DNA. What may be even more interesting to note is that these external stressors are not simply confined to illnesses usually associated with aging, but can be evident in maturing and young individuals. A broad range of internationally recognized experts have contributed to this book. Their aim is to successfully highlight emerging knowledge and therapy for the understanding of the basis and development of aging–related disorders.

Accenting Lipid Peroxidation

Download Accenting Lipid Peroxidation PDF Online Free

Author :
Publisher : BoD – Books on Demand
ISBN 13 : 1839688254
Total Pages : 160 pages
Book Rating : 4.8/5 (396 download)

DOWNLOAD NOW!


Book Synopsis Accenting Lipid Peroxidation by : Pınar Atukeren

Download or read book Accenting Lipid Peroxidation written by Pınar Atukeren and published by BoD – Books on Demand. This book was released on 2021-12-08 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lipid peroxidation can occur via either enzymatic or nonenzymatic reactions due to excess production of free radical molecules. This process culminates in cellular damage causing various diseases. This book examines lipid peroxidation as a current and future biomarker of oxidative stress.

Lipid Domains

Download Lipid Domains PDF Online Free

Author :
Publisher : Academic Press
ISBN 13 : 0128033274
Total Pages : 393 pages
Book Rating : 4.1/5 (28 download)

DOWNLOAD NOW!


Book Synopsis Lipid Domains by :

Download or read book Lipid Domains written by and published by Academic Press. This book was released on 2015-06-08 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current Topics in Membranes is targeted toward scientists and researchers in biochemistry and molecular and cellular biology, providing the necessary membrane research to assist them in discovering the current state of a particular field and in learning where that field is heading. This volume offers an up to date presentation of current knowledge in the field of Lipid Domains. Written by leading experts Contains original material, both textual and illustrative, that should become a very relevant reference material The material is presented in a very comprehensive manner Both researchers in the field and general readers should find relevant and up-to-date information

Recent Advances in Psychology and Aging

Download Recent Advances in Psychology and Aging PDF Online Free

Author :
Publisher : Elsevier
ISBN 13 : 0080522785
Total Pages : 271 pages
Book Rating : 4.0/5 (85 download)

DOWNLOAD NOW!


Book Synopsis Recent Advances in Psychology and Aging by : P. Costa

Download or read book Recent Advances in Psychology and Aging written by P. Costa and published by Elsevier. This book was released on 2003-12-10 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent Events in the Psychology of Aging documents the successful integration of aging into the mainstream of psychology. Leading psychologists present overviews of the key issues and research findings on mainstream topics. These include cognitive neuroscience, visual attention, learning, memory and cognition, as well as personality and happiness. The intersection of aging content with mainstream psychology is also prominent in the areas of emotions, personality, and social psychology as seen in the chapters on subjective well-being, emotional development, self-esteem and personality trajectories. The seven chapters of this book offer information on such topics as: the seven sins of memory, categorizing the common breakdowns of memory in everyday life and the special breakdown of sins that increase with aging; problems with attention and learning; and offers answers to questions such as do emotions get blunted with age; do older people focus more on positive feelings; and the age old question of whether older people are happier than younger people is given in the chapter on the evolving concept of subjective well-being and the multifaceted nature of happiness. Questions about what occurs to one's self-esteem and personality are also masterfully discussed and the answers may be surprising. The concluding seventh chapter provides a cultural lens on the biopsychosocial study of aging.

Redox Signaling and Regulation in Biology and Medicine

Download Redox Signaling and Regulation in Biology and Medicine PDF Online Free

Author :
Publisher : John Wiley & Sons
ISBN 13 : 3527627596
Total Pages : 514 pages
Book Rating : 4.5/5 (276 download)

DOWNLOAD NOW!


Book Synopsis Redox Signaling and Regulation in Biology and Medicine by : Claus Jacob

Download or read book Redox Signaling and Regulation in Biology and Medicine written by Claus Jacob and published by John Wiley & Sons. This book was released on 2009-05-06 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first entry-level guide to the multifaceted field takes readers one step further than existing textbooks. In an easily accessible manner, the authors integrate the biochemistry, cell biology and medical implications of intracellular redox processes, demonstrating that complex science can be presented in a clear and almost entertaining way. Perfect for students and junior researchers, this is an equally valuable addition to courses in biochemistry, molecular biology, cell biology, and human physiology.

Membrane Biogenesis

Download Membrane Biogenesis PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642731848
Total Pages : 474 pages
Book Rating : 4.6/5 (427 download)

DOWNLOAD NOW!


Book Synopsis Membrane Biogenesis by : Jos A.F. Op den Kamp

Download or read book Membrane Biogenesis written by Jos A.F. Op den Kamp and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many individual aspects of the dynamics and assembly of biological membranes have been studied in great detail. Cell biological approaches, advanced genetics, biophysics and biochemistry have greatly contributed to an increase in our knowledge in this field.lt is obvious however, that the three major membrane constituents - lipids, proteins and carbohydrates- are studied, in most cases separately and that a coherent overview of the various aspects of membrane biogenesis is not readily available. The NATO Advanced Study Institute on "New Perspectives in the Dynamics of Assembly of Biomembranes" intended to provide such an overview: it was set up to teach students and specialists the achievements obtained in the various research areas and to try and integrate the numerous aspects of membrane assembly into a coherent framework. The articles in here reflect this. Statting with detailed contributions on phospholipid structure, dynamics, organization and biogenesis, an up to date overview of the basic, lipidic backbone of biomembranes is given. Extensive progress is made in the research on membrane protein biosynthesis. In particular the post- and co-translational modification processes of proteins, the mechanisms of protein translocation and the sorting mechanisms which are necessary to direct proteins to their final, intra - or extracellular destination have been characterized in detail. Modern genetic approaches were indispensable in this research area: gene cloning, hybrid protein construction, site directed mutagenesis and sequencing techniques elucidated many functional aspects of specific nucleic acid and amino acid sequences.

Molecular Biology of Aging

Download Molecular Biology of Aging PDF Online Free

Author :
Publisher : CSHL Press
ISBN 13 : 0879698241
Total Pages : 610 pages
Book Rating : 4.8/5 (796 download)

DOWNLOAD NOW!


Book Synopsis Molecular Biology of Aging by : Leonard Guarente

Download or read book Molecular Biology of Aging written by Leonard Guarente and published by CSHL Press. This book was released on 2008 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume covers the major threads in the molecular genetics of aging, including genes that regulate aging, causes of aging, evolutionary theories of aging, and the relationship between diet and aging. Among specific topics covered are calorie restriction, mitochondria, sirtuins, telomeres, stem cells, and cancer.