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Membrane Defenses Against Attack By Complement And Perforins
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Book Synopsis Membrane Defenses Against Attack by Complement and Perforins by : Charles J. Parker
Download or read book Membrane Defenses Against Attack by Complement and Perforins written by Charles J. Parker and published by Springer. This book was released on 2011-12-27 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this volume a comprehensive review of membrane proteins that regulate complement and perforin-mediated cytolysis is presented. A detailed analysisis provided of the biochemical, molecular, and functional features of these proteins; the glycosyl phosphatidylinositol linked proteins are covered, with emphasis placed on the functional importance of this type of membrane anchor. Further chapters include reviews of the effects of complement activation on cells that are metabolically active, and of the regulation of cell killing by cytotoxic lymphocytes, considering the similarities and disparities between the complement and perforin systems. The therapeutic use of recombinant CR1 for immune-mediated pathophysiological processes is discussed in a separate section.
Book Synopsis Membrane Defenses Against Attack by Complement and Perforins by : Charles J. Parker
Download or read book Membrane Defenses Against Attack by Complement and Perforins written by Charles J. Parker and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this volume a comprehensive review of membrane proteins that regulate complement and perforin-mediated cytolysis is presented. A detailed analysisis provided of the biochemical, molecular, and functional features of these proteins; the glycosyl phosphatidylinositol linked proteins are covered, with emphasis placed on the functional importance of this type of membrane anchor. Further chapters include reviews of the effects of complement activation on cells that are metabolically active, and of the regulation of cell killing by cytotoxic lymphocytes, considering the similarities and disparities between the complement and perforin systems. The therapeutic use of recombinant CR1 for immune-mediated pathophysiological processes is discussed in a separate section.
Book Synopsis Perforin and the Membrane Attack Complex of Complement by : J. Jones
Download or read book Perforin and the Membrane Attack Complex of Complement written by J. Jones and published by . This book was released on 1992 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Complement System by : K. Rother
Download or read book The Complement System written by K. Rother and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of the former editions remains unchanged in the present updated version, namely to put forward a general and comprehensive review on complement. It is intended not only for individual investigators working in this specific field, but also for those who are less familiar with it. Students or younger scientists will hopefully be stimulated and attracted by the fascination of complement biology. Again, it was clear from the beginning that the field has experienced an explosive expansion in various directions and continues to accumulate data too large to be dealt with by a single author in a critical and coherent manner. The editors are grateful that the invited authors, all of them leading scientists in their field, helped again to make The Complement System a true mirror of the state of the art. Some parallels in the various chapters were accepted, as was a particular emphasis on newer developments in some chapters.
Book Synopsis Janeway's Immunobiology by : Kenneth Murphy
Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Book Synopsis MACPF/CDC Proteins - Agents of Defence, Attack and Invasion by : Gregor Anderluh
Download or read book MACPF/CDC Proteins - Agents of Defence, Attack and Invasion written by Gregor Anderluh and published by Springer. This book was released on 2014-05-05 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focusses on evolutionary, structural and functional aspects of pore-forming proteins, bringing together prominent researchers in the fields of structural biology and cellular and biophysical techniques. The focus is on the MACPF/CDC protein super family that was originally discovered because of unexpected structural similarity between a domain present in bacterial cholesterol-dependent cytolysins (CDC) and proteins of the membrane attack complex/perforin (MACPF) family. Members of the MACPF/CDC super family are crucial for many biological processes, being efficient agents of development, defence, attack and invasion of cells and tissues. However, their best-known role is in bacterial pathogenesis and the proper functioning of the vertebrate immune system, via formation of transmembrane pores in target cell membranes. The book contains chapters on the distribution of MACPF/CDC proteins and on aspects of their evolution and structural properties, the similarities between different super family members and functional properties of some of the best known examples. The book also contains an overview of biophysical approaches that may be used in the future to provide further insights into how these interesting proteins function.
Book Synopsis Complement Regulatory Proteins by : B. Paul Morgan
Download or read book Complement Regulatory Proteins written by B. Paul Morgan and published by Academic Press. This book was released on 1999-02-18 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: From small beginnings in the early 1970s, the study of complement regulatory proteins has grown in the last decade to the point where it dominates the complement field. This growth has been fueled by the discovery of new regulators, the cloning of old and new regulators, the discovery that many of the regulators are structurally and evolutionarily related to each other and the development of recombinant forms for use in therapy. There are now more proteins known to be involved in controlling the complement system than there are components of the system and the list continues to grow. The time is ripe for a comprehensive review of our current knowledge of these intriguing proteins. This book does just that. The first few chapters discuss the "nuts-and-bolts" of the complement regulators, describing their structures, functional roles and modes of action. The roles of the complement regulators in vivo are then described, focusing on the consequences of deficiency, roles in the reproductive system, interactions with pathogens and exploitation for therapy. The interesting developments in defining the complement regulators expressed in other species are also discussed. The book is written as a monograph, albeit by two people. The text is as readable as possible without compromising on scientific accuracy and completeness. The conversational style very evident in some sections is deliberate! Placing all references in a single bibliography at the end of the text further improves readability. The reader will go to the book to discover a specific fact but be persuaded to read more and derive pleasure from the process. The authors' enthusiasm for the subject comes over strongly in the text, and this enthusiasm proves infectious. - Complement regulators--structure, functional roles and mode of action - Comprehensive reviews of each of the individual regulators - Roles of Complement regulators in vivo,in health and disease: - Consequences of deficiency - Roles in the reproductive system - Interactions with pathogens - Exploitation for therapy - Complement regulators in other species
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Immunochemistry written by Vanoss and published by CRC Press. This book was released on 1994-08-24 with total page 1092 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work offers comprehensive coverage of the chemical and physicochemical aspects of immunological interactions, as well as the molecules and moieties involved in these interactions. It covers in detail the Ag-Ab interaction, including attraction at a distance between epitope and paratope. College or university bookstores may order five or more copies at a special student price, available upon request.
Download or read book Immunobiology written by Edward Bittar and published by Elsevier. This book was released on 1996-12-17 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: As this volume demonstrates, immunobiology is a young science which is undergoing explosive growth. Judged by results, it is already an elaborate discipline which cuts across every other area in biomedical research and even has its own vocabolary (e.g., the "veto" effect). Rather than inculcate the habit of superficial learning by having the student go through a maze of details, we have sought to gather together sixteen essays that range from T-cells to psyhoneuroimmunology. This is keeping with the growing understanding that the student is expected to read and think far more for herself/himself.Next to nothing is known about innate immunity. However, recent evidence suggests that collectins might bridge the gap between innate immunity and specific clonal immune responses. Collectins are soluble effector proteins that include serum mannose-binding protein, and lung surfactants A and D. They are considered to be ante-antibodies.
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1989 with total page 1422 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Antithrombotic and Anti-complement Effects of a Heparin Cofactor II Agonist, Intimatan, Dermatan 4,6-O-disulfate by : TingTing Hong
Download or read book The Antithrombotic and Anti-complement Effects of a Heparin Cofactor II Agonist, Intimatan, Dermatan 4,6-O-disulfate written by TingTing Hong and published by . This book was released on 2005 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Current Topics in Membranes and Transport by :
Download or read book Current Topics in Membranes and Transport written by and published by Academic Press. This book was released on 1990-08-10 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current Topics in Membranes and Transport
Book Synopsis Intracellular Calcium by : Anthony K. Campbell
Download or read book Intracellular Calcium written by Anthony K. Campbell and published by John Wiley & Sons. This book was released on 2014-10-14 with total page 848 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thousands of imaginative scientists, over more than a century,have revealed the fascinating story of intracellular calcium,through a pathway of ingenious invention and discovery. Intracellular Calcium, the definitive book on this topic,reveals: The pathway of discovery and invention of intracellular calciumover more than 100 years. The evidence for intracellular calcium as a universal switch inall animal, plant, fungal and microbial cells How the components required for calcium signalling are namedand classified. The ingenious technology, which has been developed to studyintracellular calcium. How calcium is regulated inside cells and how it works totrigger an event. The role of intracellular calcium in disease, cell injury andcell death. How many drugs work through the calcium signalling system. How intracellular calcium is involved in the action of manynatural toxins. How the intracellular calcium signalling system has evolvedover 4000 million years, showing why it was crucial to the originof life. A key principle presented throughout the book is the molecularvariation upon which the intracellular calcium signalling systemdepends. This variation occurs within the same cell type andbetween cells with different functions, providing the invisiblematrix upon which Darwin and Wallace’s Natural Selectiondepends. Featuring more than 100 figures, including detailed chemicalstructures as well as pictures of key pioneers in the field, abibliography of more than 1500 references, as well asdetailed subject and organism indices, this definitive workprovides a unique source of scholarship for teachers andresearchers in the biomedical sciences and beyond.
Book Synopsis Biotechnology & Genetic Engineering Reviews by : Stephen Harding
Download or read book Biotechnology & Genetic Engineering Reviews written by Stephen Harding and published by Nottingham University Press. This book was released on 2010-05-01 with total page 439 pages. Available in PDF, EPUB and Kindle. Book excerpt: Containing more than a dozen original, major review articles from authors published in leading journals and covering important developments in industrial, agricultural, and medical applications of biotechnology, this newest edition from the well-established hardcover review series focuses primarily on the genetic manipulation of organisms. Covering issues ranging from gene expression and genetic regulations to plant bioreactors and enzymatic processing, this reference will benefit students in the fields of biochemistry, genetics, molecular biology, and pharmaceutical sciences.
Book Synopsis Perforins and Cholesterol-Dependent Cytolysins in Immunity and Pathogenesis by : George P. Munson
Download or read book Perforins and Cholesterol-Dependent Cytolysins in Immunity and Pathogenesis written by George P. Munson and published by Frontiers Media SA. This book was released on 2022-07-25 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis National Library of Medicine Current Catalog by : National Library of Medicine (U.S.)
Download or read book National Library of Medicine Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1993 with total page 1328 pages. Available in PDF, EPUB and Kindle. Book excerpt:
