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Author : Yuan Lin
Publisher : Frontiers Media SA
ISBN 13 : 2889743667
Total Pages : 168 pages
Book Rating : 4.8/5 (897 download)
Download or read book Membrane and Cytoskeleton Mechanics written by Yuan Lin and published by Frontiers Media SA. This book was released on 2022-02-11 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : David H. Boal
Publisher : Cambridge University Press
ISBN 13 : 0521113768
Total Pages : 623 pages
Book Rating : 4.5/5 (211 download)
Download or read book Mechanics of the Cell written by David H. Boal and published by Cambridge University Press. This book was released on 2012-01-19 with total page 623 pages. Available in PDF, EPUB and Kindle. Book excerpt: New edition exploring the mechanical features of biological cells for advanced undergraduate and graduate students in physics and biomedical engineering.
Author : Mohammad R. K. Mofrad
Publisher : Cambridge University Press
ISBN 13 : 1139458108
Total Pages : 231 pages
Book Rating : 4.1/5 (394 download)
Download or read book Cytoskeletal Mechanics written by Mohammad R. K. Mofrad and published by Cambridge University Press. This book was released on 2006-09-04 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a full spectrum of views on current approaches to modeling cell mechanics. The authors come from the biophysics, bioengineering and physical chemistry communities and each joins the discussion with a unique perspective on biological systems. Consequently, the approaches range from finite element methods commonly used in continuum mechanics to models of the cytoskeleton as a cross-linked polymer network to models of glassy materials and gels. Studies reflect both the static, instantaneous nature of the structure, as well as its dynamic nature due to polymerization and the full array of biological processes. While it is unlikely that a single unifying approach will evolve from this diversity, it is the hope that a better appreciation of the various perspectives will lead to a highly coordinated approach to exploring the essential problems and better discussions among investigators with differing views.
Author : Roland Kaunas
Publisher : CRC Press
ISBN 13 : 1466553812
Total Pages : 380 pages
Book Rating : 4.4/5 (665 download)
Download or read book Cell and Matrix Mechanics written by Roland Kaunas and published by CRC Press. This book was released on 2014-10-23 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explores a Range of Multiscale Biomechanics/Mechanobiology Concepts Cell and Matrix Mechanics presents cutting-edge research at the molecular, cellular, and tissue levels in the field of cell mechanics. This book involves key experts in the field, and covers crucial areas of cell and tissue mechanics, with an emphasis on the roles of mechanical forces in cell–matrix interactions. Providing material in each chapter that builds on the previous chapters, it effectively integrates length scales and contains, for each length scale, key experimental observations and corresponding quantitative theoretical models. Summarizes the Three Hierarchical Levels of Cell Mechanics The book contains 14 chapters and is organized into three sections. The first section focuses on the molecular level, the second section details mechanics at the cellular level, and the third section explores cellular mechanics at the tissue level. The authors offer a thorough description of the roles of mechanical forces in cell and tissue biology, and include specific examples. They incorporate descriptions of associated theoretical models, and provide the data and modeling framework needed for a multi-scale analysis. In addition, they highlight the pioneering studies in cell–matrix mechanics by Albert K. Harris. The topics covered include: The passive and active mechanical properties of cytoskeletal polymers and associated motor proteins along with the behavior of polymer networks The mechanical properties of the cell membrane, with an emphasis on membrane protein activation caused by membrane forces The hierarchical organization of collagen fibrils, revealing that a delicate balance exists between specific and nonspecific interactions to result in a structure with semicrystalline order as well as loose associations The roles of matrix mechanical properties on cell adhesion and function along with different mechanical mechanisms of cell–cell interactions The effects of mechanical loading on cell cytoskeletal remodeling, summarizing various modeling approaches that explain possible mechanisms regulating the alignment of actin stress fibers in response to stretching The mechanical testing of cell-populated collagen matrices, along with theory relating the passive and active mechanical properties of the engineered tissues Cell migration behavior in 3-D matrices and in collective cell motility The role of mechanics in cartilage development The roles of both cellular and external forces on tissue morphogenesis The roles of mechanical forces on tumor growth and cancer metastasis Cell and Matrix Mechanics succinctly and systematically explains the roles of mechanical forces in cell–matrix biology. Practitioners and researchers in engineering and physics, as well as graduate students in biomedical engineering and mechanical engineering related to mechanobiology, can benefit from this work.
Author : David Shearer
Publisher :
ISBN 13 :
Total Pages : 58 pages
Book Rating : 4.:/5 (575 download)
Download or read book The Effects of Membrane and Cytoskeletal Mechanics on Cell Adhesiveness written by David Shearer and published by . This book was released on 2004 with total page 58 pages. Available in PDF, EPUB and Kindle. Book excerpt: The cytoskeleton, the internal network of filaments that regulates cell shape and structure, has been implicated in several critical aspects of cell adhesion. Its role, however, has primarily been demonstrated as a component of the numerous intracellular signaling events that regulate cell surface receptors. In this study we sought to gain insight into how the mechanical properties of the cytoskeleton could affect adhesion. Specifically, we addressed how membrane deformability, which we demonstrate is critically dependent upon tethering to the cytoskeleton, could impact a whole cell adhesion assay. To modify membrane deformability, we treated cells with the pharmacological agents phalloidin, Latrinculin B, Cytochalasin D, colchicine, and Paclitaxel, which have varying effects on microfilaments and microtubules, two of the main constituents of the cytoskeleton. We found that dissolution of the actin cytoskeleton could reduce the number of adherent cells to a callogen-coated substrate by over 85%. We theorize that this is due largely to the inhibition of signaling events associated with the cytoskeleton, but it may also be affected by changes in shape and deformability. To truly understand the implications of this experiment, we believe further study using high-resolution force technology such as atomic force microscopy or magnetic bead microrheometry is necessary.
Author : Jürgen Bereiter-Hahn
Publisher : Springer Science & Business Media
ISBN 13 : 3642728634
Total Pages : 304 pages
Book Rating : 4.6/5 (427 download)
Download or read book Cytomechanics written by Jürgen Bereiter-Hahn and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic information determines the composition of molecules comprising cytoskeletal elements, membranes and receptors. The supramolecular arrangement of these components represents a self-assembly process controlled by physicochemical and mechanical interactions. This general hypothesis demarcates the aim of studying cellular mechanics. Description and evaluation of mechanical properties of cells and their organelles, as well as of the forces exerted by them, is the scope of this book on Cytomechanics. Emphasis is laid on the role of mechanical properties in the generation of shape and cytoplasmic motion, and on the basic principles and components determining mechanical properties.
Author : Ting Gang Chew
Publisher : Frontiers Media SA
ISBN 13 : 2889741605
Total Pages : 151 pages
Book Rating : 4.8/5 (897 download)
Download or read book Cytoskeletal Dynamics and Mechanics in Cell Growth, Division, Differentiation and Aging written by Ting Gang Chew and published by Frontiers Media SA. This book was released on 2022-01-25 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : James Spudich
Publisher :
ISBN 13 : 9780824331733
Total Pages : 0 pages
Book Rating : 4.3/5 (317 download)
Download or read book The Cytoskeleton written by James Spudich and published by . This book was released on 1996 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Mussie Kidane Araya
Publisher :
ISBN 13 :
Total Pages : 118 pages
Book Rating : 4.:/5 (113 download)
Download or read book Differences in Plasma Membrane Mechanics Between Neuronal Domains and Underlying Membrane Cytoskeleton Interaction written by Mussie Kidane Araya and published by . This book was released on 2019 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Amit Gefen
Publisher : Springer Science & Business Media
ISBN 13 : 3642142184
Total Pages : 553 pages
Book Rating : 4.6/5 (421 download)
Download or read book Cellular and Biomolecular Mechanics and Mechanobiology written by Amit Gefen and published by Springer Science & Business Media. This book was released on 2010-12-02 with total page 553 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes these exciting new developments, and presents experimental and computational findings that altogether describe the frontier of knowledge in cellular and biomolecular mechanics, and the biological implications, in health and disease. The book is written for bioengineers with interest in cellular mechanics, for biophysicists, biochemists, medical researchers and all other professionals with interest in how cells produce and respond to mechanical loads.
Author : Patricia Bassereau
Publisher : Springer
ISBN 13 : 3030006301
Total Pages : 616 pages
Book Rating : 4.0/5 (3 download)
Download or read book Physics of Biological Membranes written by Patricia Bassereau and published by Springer. This book was released on 2018-12-30 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book mainly focuses on key aspects of biomembranes that have emerged over the past 15 years. It covers static and dynamic descriptions, as well as modeling for membrane organization and shape at the local and global (at the cell level) scale. It also discusses several new developments in non-equilibrium aspects that have not yet been covered elsewhere. Biological membranes are the seat of interactions between cells and the rest of the world, and internally, they are at the core of complex dynamic reorganizations and chemical reactions. Despite the long tradition of membrane research in biophysics, the physics of cell membranes as well as of biomimetic or synthetic membranes is a rapidly developing field. Though successful books have already been published on this topic over the past decades, none include the most recent advances. Additionally, in this domain, the traditional distinction between biological and physical approaches tends to blur. This book gathers the most recent advances in this area, and will benefit biologists and physicists alike.
Author : David Boal
Publisher : Cambridge University Press
ISBN 13 : 1139501771
Total Pages : 623 pages
Book Rating : 4.1/5 (395 download)
Download or read book Mechanics of the Cell written by David Boal and published by Cambridge University Press. This book was released on 2012-01-19 with total page 623 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exploring the mechanical features of biological cells, including their architecture and stability, this textbook is a pedagogical introduction to the interdisciplinary fields of cell mechanics and soft matter physics from both experimental and theoretical perspectives. This second edition has been greatly updated and expanded, with new chapters on complex filaments, the cell division cycle, the mechanisms of control and organization in the cell, and fluctuation phenomena. The textbook is now in full color which enhances the diagrams and allows the inclusion of new microscopy images. With around 280 end-of-chapter exercises exploring further applications, this textbook is ideal for advanced undergraduate and graduate students in physics and biomedical engineering. A website hosted by the author contains extra support material, diagrams and lecture notes, and is available at www.cambridge.org/Boal.
Author : Jonathan M. Lee
Publisher : Biota Publishing
ISBN 13 : 1615043896
Total Pages : 82 pages
Book Rating : 4.6/5 (15 download)
Download or read book The Actin Cytoskeleton and the Regulation of Cell Migration written by Jonathan M. Lee and published by Biota Publishing. This book was released on 2013-06-01 with total page 82 pages. Available in PDF, EPUB and Kindle. Book excerpt: The mammalian cytoskeleton is an internal framework of actin, tubulin, and intermediate filament proteins. Proteins of these three classes assemble non-covalently into filamentous polymers that support the structural integrity of the relatively fragile lipid plasma membrane. In addition, cytoskeletal polymers provide the mechanical strength that hold a cell together and anchor it to its growth substrate. The cytoskeleton must also have the capacity for rapid and substantial remodeling and provide the motive and tractor force necessary to drive motility. As such, the cytoskeleton has a functional duality: sufficiently rigid to prevent plasma membrane deformation but pliable enough to allow for cytokinesis; sufficiently adhesive to allow for traction but dynamic enough to allow movement from one place to another. A major research challenge in cytoskeleton biology is to understand how cytoskeletal proteins assemble and dissemble in support of physiological processes. This chapter will focus on the role of the actin cytoskeleton in cell migration. More specifically, we will focus on the actin cytoskeleton of vertebrate cells. Table of Contents: Introduction / The Fundamentals of Actin Polymerization / Accessory Proteins Regulate Actin Polymerization and Assembly / Cellular Actin Structure / Cell Migration / Summary of Cell Migration / References / Author Biography
Author : Sarmini Nageswaran
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (135 download)
Download or read book Structure and Mechanics of Membrane-bound Vimentin Filaments and Networks Under Strain written by Sarmini Nageswaran and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The shape and mechanical properties of eukaryotic cells are determined by the cytoskeleton, composed of actin filaments, microtubules and intermediate filaments (IFs). Among these, IFs are considered to be the main determinants of cell stiffness and strength. The reason for this is that they can withstand much larger deformations than the other two filament classes. Previous studies have revealed a rim-and-spoke arrangement of IFs, suggesting that they are involved not only in themechanical stability of the cytoplasm but also of the plasma membrane. Therefore, the organization of IFs at the...
Author : Margaret Gardel
Publisher : Biota Publishing
ISBN 13 : 1615046992
Total Pages : 77 pages
Book Rating : 4.6/5 (15 download)
Download or read book Measuring Cell Mechanics written by Margaret Gardel and published by Biota Publishing. This book was released on 2015-09-01 with total page 77 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cells are inherently physical entities that both experience mechanical forces from their external environment and generate their own internal forces to drive cell motion. Our particular aim here is to present the reader with an introduction to the primary tools used to measure these mechanical interactions and the material properties of cells that result from them. These approaches can be applied to a diverse array of physiological processes and systems, providing important insight into the regulatory roles of mechanical interactions in cells. We cover techniques at both the molecular and cellular scales, including those that actively and passively probe the system. Along the way we cover the fundamental principles of each approach, while emphasizing the relevant length and timescales, along with the typical magnitudes of the measurements that can be made. Each section ends by highlighting uses of the various techniques in recent relevant publications, illustrating the exciting future of cell mechanics in quantitative cell biology research.
Author : Nuri Akkas
Publisher :
ISBN 13 : 9781468412727
Total Pages : 384 pages
Book Rating : 4.4/5 (127 download)
Download or read book Biomechanics of Cell Division written by Nuri Akkas and published by . This book was released on 2014-01-15 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt:
