Medical Isotope Production Without Highly Enriched Uranium

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Publisher : National Academies Press
ISBN 13 : 0309130395
Total Pages : 220 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Medical Isotope Production Without Highly Enriched Uranium by : National Research Council

Download or read book Medical Isotope Production Without Highly Enriched Uranium written by National Research Council and published by National Academies Press. This book was released on 2009-06-27 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the product of a congressionally mandated study to examine the feasibility of eliminating the use of highly enriched uranium (HEU2) in reactor fuel, reactor targets, and medical isotope production facilities. The book focuses primarily on the use of HEU for the production of the medical isotope molybdenum-99 (Mo-99), whose decay product, technetium-99m3 (Tc-99m), is used in the majority of medical diagnostic imaging procedures in the United States, and secondarily on the use of HEU for research and test reactor fuel. The supply of Mo-99 in the U.S. is likely to be unreliable until newer production sources come online. The reliability of the current supply system is an important medical isotope concern; this book concludes that achieving a cost difference of less than 10 percent in facilities that will need to convert from HEU- to LEU-based Mo-99 production is much less important than is reliability of supply.

Molybdenum-99 for Medical Imaging

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Publisher : National Academies Press
ISBN 13 : 0309445310
Total Pages : 264 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Molybdenum-99 for Medical Imaging by : National Academies of Sciences, Engineering, and Medicine

Download or read book Molybdenum-99 for Medical Imaging written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-11-28 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: The decay product of the medical isotope molybdenum-99 (Mo-99), technetium-99m (Tc-99m), and associated medical isotopes iodine-131 (I-131) and xenon-133 (Xe-133) are used worldwide for medical diagnostic imaging or therapy. The United States consumes about half of the world's supply of Mo-99, but there has been no domestic (i.e., U.S.-based) production of this isotope since the late 1980s. The United States imports Mo-99 for domestic use from Australia, Canada, Europe, and South Africa. Mo-99 and Tc-99m cannot be stockpiled for use because of their short half-lives. Consequently, they must be routinely produced and delivered to medical imaging centers. Almost all Mo-99 for medical use is produced by irradiating highly enriched uranium (HEU) targets in research reactors, several of which are over 50 years old and are approaching the end of their operating lives. Unanticipated and extended shutdowns of some of these old reactors have resulted in severe Mo-99 supply shortages in the United States and other countries. Some of these shortages have disrupted the delivery of medical care. Molybdenum-99 for Medical Imaging examines the production and utilization of Mo-99 and associated medical isotopes, and provides recommendations for medical use.

Opportunities and Approaches for Supplying Molybdenum-99 and Associated Medical Isotopes to Global Markets

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Publisher : National Academies Press
ISBN 13 : 030946627X
Total Pages : 87 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Opportunities and Approaches for Supplying Molybdenum-99 and Associated Medical Isotopes to Global Markets by : National Academies of Sciences, Engineering, and Medicine

Download or read book Opportunities and Approaches for Supplying Molybdenum-99 and Associated Medical Isotopes to Global Markets written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2018-03-12 with total page 87 pages. Available in PDF, EPUB and Kindle. Book excerpt: Participants of the July 17-18, 2017, symposium titled Opportunities and Approaches for Supplying Molybdenum-99 and Associated Medical Isotopes to Global Markets examined current trends in molybdenum-99 production, prospects for new global supplies, and technical, economic, regulatory, and other considerations for supplying molybdenum-99 to global markets. This publication summarizes the presentations and discussions from the symposium.

The Supply of Medical Isotopes

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Publisher :
ISBN 13 : 9789264625099
Total Pages : 122 pages
Book Rating : 4.6/5 (25 download)

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Book Synopsis The Supply of Medical Isotopes by :

Download or read book The Supply of Medical Isotopes written by and published by . This book was released on 2019 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report explores the main reasons behind the unreliable supply of Technetium-99m (Tc-99m) in health-care systems and policy options to address the issue. Tc-99m is used in 85% of nuclear medicine diagnostic scans performed worldwide – around 30 million patient examinations every year. These scans allow diagnoses of diseases in many parts of the human body, including the skeleton, heart and circulatory system, and the brain. Medical isotopes are subject to radioactive decay and have to be delivered just-in-time through a complex supply chain. However, ageing production facilities and a lack of investment have made the supply of Tc-99m unreliable. This report analyses the use and substitutability of Tc-99m in health care, health-care provider payment mechanisms for scans, and the structure of the supply chain. It concludes that the main reasons for unreliable supply are that production is not economically viable and that the structure of the supply chain prevents producers from charging prices that reflect the full costs of production and supply.

Isotopes for Medicine and the Life Sciences

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Publisher : National Academies Press
ISBN 13 : 0309176697
Total Pages : 144 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Isotopes for Medicine and the Life Sciences by : Institute of Medicine

Download or read book Isotopes for Medicine and the Life Sciences written by Institute of Medicine and published by National Academies Press. This book was released on 1995-01-27 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radioactive isotopes and enriched stable isotopes are used widely in medicine, agriculture, industry, and science, where their application allows us to perform many tasks more accurately, more simply, less expensively, and more quickly than would otherwise be possible. Indeed, in many casesâ€"for example, biological tracersâ€"there is no alternative. In a stellar example of "technology transfer" that began before the term was popular, the Department of Energy (DOE) and its predecessors has supported the development and application of isotopes and their transfer to the private sector. The DOE is now at an important crossroads: Isotope production has suffered as support for DOE's laboratories has declined. In response to a DOE request, this book is an intensive examination of isotope production and availability, including the education and training of those who will be needed to sustain the flow of radioactive and stable materials from their sources to the laboratories and medical care facilities in which they are used. Chapters include an examination of enriched stable isotopes; reactor and accelerator-produced radionuclides; partnerships among industries, national laboratories, and universities; and national isotope policy.

Advancing Nuclear Medicine Through Innovation

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Publisher : National Academies Press
ISBN 13 : 0309134153
Total Pages : 173 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Advancing Nuclear Medicine Through Innovation by : National Research Council

Download or read book Advancing Nuclear Medicine Through Innovation written by National Research Council and published by National Academies Press. This book was released on 2007-09-11 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nearly 20 million nuclear medicine procedures are carried out each year in the United States alone to diagnose and treat cancers, cardiovascular disease, and certain neurological disorders. Many of the advancements in nuclear medicine have been the result of research investments made during the past 50 years where these procedures are now a routine part of clinical care. Although nuclear medicine plays an important role in biomedical research and disease management, its promise is only beginning to be realized. Advancing Nuclear Medicine Through Innovation highlights the exciting emerging opportunities in nuclear medicine, which include assessing the efficacy of new drugs in development, individualizing treatment to the patient, and understanding the biology of human diseases. Health care and pharmaceutical professionals will be most interested in this book's examination of the challenges the field faces and its recommendations for ways to reduce these impediments.

Life Atomic

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Publisher : University of Chicago Press
ISBN 13 : 022601794X
Total Pages : 506 pages
Book Rating : 4.2/5 (26 download)

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Book Synopsis Life Atomic by : Angela N. H. Creager

Download or read book Life Atomic written by Angela N. H. Creager and published by University of Chicago Press. This book was released on 2013-10-02 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: After World War II, the US Atomic Energy Commission (AEC) began mass-producing radioisotopes, sending out nearly 64,000 shipments of radioactive materials to scientists and physicians by 1955. Even as the atomic bomb became the focus of Cold War anxiety, radioisotopes represented the government’s efforts to harness the power of the atom for peace—advancing medicine, domestic energy, and foreign relations. In Life Atomic, Angela N. H. Creager tells the story of how these radioisotopes, which were simultaneously scientific tools and political icons, transformed biomedicine and ecology. Government-produced radioisotopes provided physicians with new tools for diagnosis and therapy, specifically cancer therapy, and enabled biologists to trace molecular transformations. Yet the government’s attempt to present radioisotopes as marvelous dividends of the atomic age was undercut in the 1950s by the fallout debates, as scientists and citizens recognized the hazards of low-level radiation. Creager reveals that growing consciousness of the danger of radioactivity did not reduce the demand for radioisotopes at hospitals and laboratories, but it did change their popular representation from a therapeutic agent to an environmental poison. She then demonstrates how, by the late twentieth century, public fear of radioactivity overshadowed any appreciation of the positive consequences of the AEC’s provision of radioisotopes for research and medicine.

Medical Isotopes Production Project (MIPP): Molybdenum-99 and Related Isotopes, Bernalillo County

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Author :
Publisher :
ISBN 13 :
Total Pages : 622 pages
Book Rating : 4.3/5 (555 download)

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Book Synopsis Medical Isotopes Production Project (MIPP): Molybdenum-99 and Related Isotopes, Bernalillo County by :

Download or read book Medical Isotopes Production Project (MIPP): Molybdenum-99 and Related Isotopes, Bernalillo County written by and published by . This book was released on 1996 with total page 622 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Medical Isotopes Production Project (MIPP): Molybdenum-99 and Related Isotopes, Bernalillo County

Download Medical Isotopes Production Project (MIPP): Molybdenum-99 and Related Isotopes, Bernalillo County PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : 476 pages
Book Rating : 4.3/5 (555 download)

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Book Synopsis Medical Isotopes Production Project (MIPP): Molybdenum-99 and Related Isotopes, Bernalillo County by : United States. Department of Energy

Download or read book Medical Isotopes Production Project (MIPP): Molybdenum-99 and Related Isotopes, Bernalillo County written by United States. Department of Energy and published by . This book was released on 1996 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt:

American Medical Isotopes Production Act

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Publisher :
ISBN 13 :
Total Pages : 18 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis American Medical Isotopes Production Act by : United States. Congress. Senate. Committee on Energy and Natural Resources

Download or read book American Medical Isotopes Production Act written by United States. Congress. Senate. Committee on Energy and Natural Resources and published by . This book was released on 2010 with total page 18 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Reducing the Use of Highly Enriched Uranium in Civilian Research Reactors

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Publisher : National Academies Press
ISBN 13 : 0309379210
Total Pages : 205 pages
Book Rating : 4.3/5 (93 download)

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Book Synopsis Reducing the Use of Highly Enriched Uranium in Civilian Research Reactors by : National Academies of Sciences, Engineering, and Medicine

Download or read book Reducing the Use of Highly Enriched Uranium in Civilian Research Reactors written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-02-12 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: The continued presence of highly enriched uranium (HEU) in civilian installations such as research reactors poses a threat to national and international security. Minimization, and ultimately elimination, of HEU in civilian research reactors worldwide has been a goal of U.S. policy and programs since 1978. Today, 74 civilian research reactors around the world, including 8 in the United States, use or are planning to use HEU fuel. Since the last National Academies of Sciences, Engineering, and Medicine report on this topic in 2009, 28 reactors have been either shut down or converted from HEU to low enriched uranium fuel. Despite this progress, the large number of remaining HEU-fueled reactors demonstrates that an HEU minimization program continues to be needed on a worldwide scale. Reducing the Use of Highly Enriched Uranium in Civilian Research Reactors assesses the status of and progress toward eliminating the worldwide use of HEU fuel in civilian research and test reactors.

Applications of Research Reactors

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Publisher : International Atomic Energy Agency
ISBN 13 : 9789201450104
Total Pages : 108 pages
Book Rating : 4.4/5 (51 download)

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Book Synopsis Applications of Research Reactors by : International Atomic Energy Agency

Download or read book Applications of Research Reactors written by International Atomic Energy Agency and published by International Atomic Energy Agency. This book was released on 2014 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication is a comprehensive study that reviews the current situation in a great number of applications of research reactors. It revises the contents of IAEA TECDOC-1234, The Applications of Research Reactors, giving detailed updates on each field of research reactor uses worldwide. Reactors of all sizes and capabilities can benefit from the sharing of current practices and research enabled via this updated version, which describes the requirements for practicing methods as diverse as neutron activation analysis, education and training, neutron scattering and neutron imaging, silicon doping and radioisotope production, material/fuel irradiation and testing, and some others. Many underutilised research reactors can learn how to diversify their technical capabilities, staff and potential commercial partners and users seeking research reactor services and products. The content of the publication has also been strengthened in terms of current issues facing the vast majority of research reactors by including sections describing user and customer relations as well as strategic planning considerations.

Radioisotope Handling Facilities and Automation of Radioisotope Production

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Publisher : IAEA
ISBN 13 :
Total Pages : 78 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Radioisotope Handling Facilities and Automation of Radioisotope Production by : International Atomic Energy Agency

Download or read book Radioisotope Handling Facilities and Automation of Radioisotope Production written by International Atomic Energy Agency and published by IAEA. This book was released on 2004 with total page 78 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dated December 2004

Cyclotron Based Production of Technetium-99m

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Publisher :
ISBN 13 : 9789201029164
Total Pages : 0 pages
Book Rating : 4.0/5 (291 download)

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Book Synopsis Cyclotron Based Production of Technetium-99m by : International Atomic Energy Agency

Download or read book Cyclotron Based Production of Technetium-99m written by International Atomic Energy Agency and published by . This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication presents a comprehensive overview of the technologies involved in the production of cyclotron based 99mTc. These would include techniques relevant to preparation of targets, irradiation of targets under high beam currents, target processing, target recovery and quality control of the final product. The publication provides broad information, well supported with references, on improved production routes and improved separation and purification of cyclotron based 99mTc. These approaches achieve high specific activity and chemical purity of 99mTc suitable for labelling molecules of medical interest and also enable spare capacity to be available at medical cyclotron centres. The readership of this publication is scientists interested in translating this technology to practice, technologists already working with cyclotrons wanting to enhance the utility of the existing machines and managers who are in the process of setting up facilities in their countries. Students working towards higher level degrees in related fields may also benefit from this publication.

Cyclotron Produced Radionuclides

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Publisher :
ISBN 13 : 9789201002082
Total Pages : 0 pages
Book Rating : 4.0/5 (2 download)

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Book Synopsis Cyclotron Produced Radionuclides by :

Download or read book Cyclotron Produced Radionuclides written by and published by . This book was released on 2008 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive treatment of cyclotrons, with a special emphasis on production of radionuclides. Individual sections are devoted to accelerator technology, theoretical aspects of nuclear reactions, the technology behind targetry, techniques for preparation of targets, irradiation of targets under high beam currents, target processing and target recovery. This book will appeal to scientists and technologists interested in translating cyclotron technology into practice, as well as postgraduate students in this field.

Isotopes in Agriculture

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Author :
Publisher :
ISBN 13 :
Total Pages : 476 pages
Book Rating : 4.3/5 (243 download)

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Book Synopsis Isotopes in Agriculture by :

Download or read book Isotopes in Agriculture written by and published by . This book was released on 1958 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt:

American Medical Isotopes Production Act of 2009

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Publisher :
ISBN 13 :
Total Pages : 24 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis American Medical Isotopes Production Act of 2009 by : United States. Congress. House. Committee on Energy and Commerce

Download or read book American Medical Isotopes Production Act of 2009 written by United States. Congress. House. Committee on Energy and Commerce and published by . This book was released on 2009 with total page 24 pages. Available in PDF, EPUB and Kindle. Book excerpt: