Medical Isotope Production Without Highly Enriched Uranium

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Publisher : National Academies Press
ISBN 13 : 0309130395
Total Pages : 220 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Medical Isotope Production Without Highly Enriched Uranium by : National Research Council

Download or read book Medical Isotope Production Without Highly Enriched Uranium written by National Research Council and published by National Academies Press. This book was released on 2009-06-27 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the product of a congressionally mandated study to examine the feasibility of eliminating the use of highly enriched uranium (HEU2) in reactor fuel, reactor targets, and medical isotope production facilities. The book focuses primarily on the use of HEU for the production of the medical isotope molybdenum-99 (Mo-99), whose decay product, technetium-99m3 (Tc-99m), is used in the majority of medical diagnostic imaging procedures in the United States, and secondarily on the use of HEU for research and test reactor fuel. The supply of Mo-99 in the U.S. is likely to be unreliable until newer production sources come online. The reliability of the current supply system is an important medical isotope concern; this book concludes that achieving a cost difference of less than 10 percent in facilities that will need to convert from HEU- to LEU-based Mo-99 production is much less important than is reliability of supply.

The Supply of Medical Isotopes

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Publisher :
ISBN 13 : 9789264625099
Total Pages : 122 pages
Book Rating : 4.6/5 (25 download)

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Book Synopsis The Supply of Medical Isotopes by :

Download or read book The Supply of Medical Isotopes written by and published by . This book was released on 2019 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report explores the main reasons behind the unreliable supply of Technetium-99m (Tc-99m) in health-care systems and policy options to address the issue. Tc-99m is used in 85% of nuclear medicine diagnostic scans performed worldwide – around 30 million patient examinations every year. These scans allow diagnoses of diseases in many parts of the human body, including the skeleton, heart and circulatory system, and the brain. Medical isotopes are subject to radioactive decay and have to be delivered just-in-time through a complex supply chain. However, ageing production facilities and a lack of investment have made the supply of Tc-99m unreliable. This report analyses the use and substitutability of Tc-99m in health care, health-care provider payment mechanisms for scans, and the structure of the supply chain. It concludes that the main reasons for unreliable supply are that production is not economically viable and that the structure of the supply chain prevents producers from charging prices that reflect the full costs of production and supply.

Molybdenum-99 for Medical Imaging

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Publisher : National Academies Press
ISBN 13 : 0309445310
Total Pages : 264 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Molybdenum-99 for Medical Imaging by : National Academies of Sciences, Engineering, and Medicine

Download or read book Molybdenum-99 for Medical Imaging written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-11-28 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: The decay product of the medical isotope molybdenum-99 (Mo-99), technetium-99m (Tc-99m), and associated medical isotopes iodine-131 (I-131) and xenon-133 (Xe-133) are used worldwide for medical diagnostic imaging or therapy. The United States consumes about half of the world's supply of Mo-99, but there has been no domestic (i.e., U.S.-based) production of this isotope since the late 1980s. The United States imports Mo-99 for domestic use from Australia, Canada, Europe, and South Africa. Mo-99 and Tc-99m cannot be stockpiled for use because of their short half-lives. Consequently, they must be routinely produced and delivered to medical imaging centers. Almost all Mo-99 for medical use is produced by irradiating highly enriched uranium (HEU) targets in research reactors, several of which are over 50 years old and are approaching the end of their operating lives. Unanticipated and extended shutdowns of some of these old reactors have resulted in severe Mo-99 supply shortages in the United States and other countries. Some of these shortages have disrupted the delivery of medical care. Molybdenum-99 for Medical Imaging examines the production and utilization of Mo-99 and associated medical isotopes, and provides recommendations for medical use.

Medical Isotopes

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Publisher : BoD – Books on Demand
ISBN 13 : 183880627X
Total Pages : 140 pages
Book Rating : 4.8/5 (388 download)

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Book Synopsis Medical Isotopes by : Syed Ali Raza Naqvi

Download or read book Medical Isotopes written by Syed Ali Raza Naqvi and published by BoD – Books on Demand. This book was released on 2021-01-07 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radioisotopes are widely used in the medical field for imaging and therapy of diseases by themselves or by tagging with other molecules that have the potential to target diseased cells. In imaging protocol, the radioisotope, such as technetium-99m or indium-111, decays through ?-radiation emissions, which are located by a scintigraphic camera (SPECT or PET) in the form of 2/3D image formation of the diseased organ. The other kind of radioisotopes, such as Lutetium-177 or Actinium-225, are those that decay through ?/?-decay, which is due to its valuable linear energy transfer that is in clinical use to eliminate diseased cells. This book will cover valuable information about selected diagnostic and therapeutic radioisotopes along with localization mechanisms of radioisotopes directly or through nanoparticles at diseased cells.

Life Atomic

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Publisher : University of Chicago Press
ISBN 13 : 022601794X
Total Pages : 506 pages
Book Rating : 4.2/5 (26 download)

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Book Synopsis Life Atomic by : Angela N. H. Creager

Download or read book Life Atomic written by Angela N. H. Creager and published by University of Chicago Press. This book was released on 2013-10-02 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: After World War II, the US Atomic Energy Commission (AEC) began mass-producing radioisotopes, sending out nearly 64,000 shipments of radioactive materials to scientists and physicians by 1955. Even as the atomic bomb became the focus of Cold War anxiety, radioisotopes represented the government’s efforts to harness the power of the atom for peace—advancing medicine, domestic energy, and foreign relations. In Life Atomic, Angela N. H. Creager tells the story of how these radioisotopes, which were simultaneously scientific tools and political icons, transformed biomedicine and ecology. Government-produced radioisotopes provided physicians with new tools for diagnosis and therapy, specifically cancer therapy, and enabled biologists to trace molecular transformations. Yet the government’s attempt to present radioisotopes as marvelous dividends of the atomic age was undercut in the 1950s by the fallout debates, as scientists and citizens recognized the hazards of low-level radiation. Creager reveals that growing consciousness of the danger of radioactivity did not reduce the demand for radioisotopes at hospitals and laboratories, but it did change their popular representation from a therapeutic agent to an environmental poison. She then demonstrates how, by the late twentieth century, public fear of radioactivity overshadowed any appreciation of the positive consequences of the AEC’s provision of radioisotopes for research and medicine.

Opportunities and Approaches for Supplying Molybdenum-99 and Associated Medical Isotopes to Global Markets

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Publisher : National Academies Press
ISBN 13 : 030946627X
Total Pages : 87 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Opportunities and Approaches for Supplying Molybdenum-99 and Associated Medical Isotopes to Global Markets by : National Academies of Sciences, Engineering, and Medicine

Download or read book Opportunities and Approaches for Supplying Molybdenum-99 and Associated Medical Isotopes to Global Markets written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2018-03-12 with total page 87 pages. Available in PDF, EPUB and Kindle. Book excerpt: Participants of the July 17-18, 2017, symposium titled Opportunities and Approaches for Supplying Molybdenum-99 and Associated Medical Isotopes to Global Markets examined current trends in molybdenum-99 production, prospects for new global supplies, and technical, economic, regulatory, and other considerations for supplying molybdenum-99 to global markets. This publication summarizes the presentations and discussions from the symposium.

Isotopes for Medicine and the Life Sciences

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Publisher : National Academies Press
ISBN 13 : 0309176697
Total Pages : 144 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Isotopes for Medicine and the Life Sciences by : Institute of Medicine

Download or read book Isotopes for Medicine and the Life Sciences written by Institute of Medicine and published by National Academies Press. This book was released on 1995-01-27 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radioactive isotopes and enriched stable isotopes are used widely in medicine, agriculture, industry, and science, where their application allows us to perform many tasks more accurately, more simply, less expensively, and more quickly than would otherwise be possible. Indeed, in many casesâ€"for example, biological tracersâ€"there is no alternative. In a stellar example of "technology transfer" that began before the term was popular, the Department of Energy (DOE) and its predecessors has supported the development and application of isotopes and their transfer to the private sector. The DOE is now at an important crossroads: Isotope production has suffered as support for DOE's laboratories has declined. In response to a DOE request, this book is an intensive examination of isotope production and availability, including the education and training of those who will be needed to sustain the flow of radioactive and stable materials from their sources to the laboratories and medical care facilities in which they are used. Chapters include an examination of enriched stable isotopes; reactor and accelerator-produced radionuclides; partnerships among industries, national laboratories, and universities; and national isotope policy.

Medical Isotopes Production Project (MIPP): Molybdenum-99 and Related Isotopes, Bernalillo County

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Author :
Publisher :
ISBN 13 :
Total Pages : 476 pages
Book Rating : 4.3/5 (555 download)

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Book Synopsis Medical Isotopes Production Project (MIPP): Molybdenum-99 and Related Isotopes, Bernalillo County by : United States. Department of Energy

Download or read book Medical Isotopes Production Project (MIPP): Molybdenum-99 and Related Isotopes, Bernalillo County written by United States. Department of Energy and published by . This book was released on 1996 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt:

American Medical Isotopes Production Act

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Publisher :
ISBN 13 :
Total Pages : 18 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis American Medical Isotopes Production Act by : United States. Congress. Senate. Committee on Energy and Natural Resources

Download or read book American Medical Isotopes Production Act written by United States. Congress. Senate. Committee on Energy and Natural Resources and published by . This book was released on 2010 with total page 18 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Radioisotopes in Medicine

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Publisher :
ISBN 13 :
Total Pages : 194 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Radioisotopes in Medicine by : Richard R. Tarrice

Download or read book Radioisotopes in Medicine written by Richard R. Tarrice and published by . This book was released on 1959 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Advancing Nuclear Medicine Through Innovation

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Publisher : National Academies Press
ISBN 13 : 0309134153
Total Pages : 173 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Advancing Nuclear Medicine Through Innovation by : National Research Council

Download or read book Advancing Nuclear Medicine Through Innovation written by National Research Council and published by National Academies Press. This book was released on 2007-09-11 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nearly 20 million nuclear medicine procedures are carried out each year in the United States alone to diagnose and treat cancers, cardiovascular disease, and certain neurological disorders. Many of the advancements in nuclear medicine have been the result of research investments made during the past 50 years where these procedures are now a routine part of clinical care. Although nuclear medicine plays an important role in biomedical research and disease management, its promise is only beginning to be realized. Advancing Nuclear Medicine Through Innovation highlights the exciting emerging opportunities in nuclear medicine, which include assessing the efficacy of new drugs in development, individualizing treatment to the patient, and understanding the biology of human diseases. Health care and pharmaceutical professionals will be most interested in this book's examination of the challenges the field faces and its recommendations for ways to reduce these impediments.

The Supply of Medical Isotopes

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Publisher : Org. for Economic Cooperation & Development
ISBN 13 : 9789264945500
Total Pages : 124 pages
Book Rating : 4.9/5 (455 download)

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Book Synopsis The Supply of Medical Isotopes by : Oecd

Download or read book The Supply of Medical Isotopes written by Oecd and published by Org. for Economic Cooperation & Development. This book was released on 2019-10-22 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Medical Isotopes

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Publisher :
ISBN 13 :
Total Pages : 56 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Medical Isotopes by : United States. Congress. Senate. Committee on Energy and Natural Resources

Download or read book Medical Isotopes written by United States. Congress. Senate. Committee on Energy and Natural Resources and published by . This book was released on 2010 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Radioactive Isotopes in Clinical Medicine and Research XXIII

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Publisher : Birkhäuser
ISBN 13 : 3034887825
Total Pages : 551 pages
Book Rating : 4.0/5 (348 download)

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Book Synopsis Radioactive Isotopes in Clinical Medicine and Research XXIII by : H. Sinzinger

Download or read book Radioactive Isotopes in Clinical Medicine and Research XXIII written by H. Sinzinger and published by Birkhäuser. This book was released on 2013-03-07 with total page 551 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radioactive Isotopes in Clinical Medicine and Research XXIII presents an update in the latest clinical research in nuclear medicine. It provides in-depth information on all areas of nuclear medicine. The chapters of this volume have been grouped into the following sections: Neurology / Psychiatry, Therapy, Radiopharmacology, Endocrinology / Thyroid, Oncology / Haematology, Clinical PET, Cardiology, Varia, Physics / Radiation Protection, World Wide Web / WWW demo. Special attention is paid to the virtual media for teaching, training, communication, quality control etc. Primarily intended for specialists in the nuclear medicine, this volume will also be of considerable interest to clinicians using diagnostic and therapeutic nuclear medicine procedures, including cardiologists, haematologists, neurologists, nephrologists, oncologists, pharmacologists, and psychiatrists.

Medical Isotopes Production Project (MIPP): Molybdenum-99 and Related Isotopes, Bernalillo County

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Author :
Publisher :
ISBN 13 :
Total Pages : 622 pages
Book Rating : 4.3/5 (555 download)

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Book Synopsis Medical Isotopes Production Project (MIPP): Molybdenum-99 and Related Isotopes, Bernalillo County by :

Download or read book Medical Isotopes Production Project (MIPP): Molybdenum-99 and Related Isotopes, Bernalillo County written by and published by . This book was released on 1996 with total page 622 pages. Available in PDF, EPUB and Kindle. Book excerpt:

American Medical Isotopes Production Act of 2009

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Author :
Publisher :
ISBN 13 :
Total Pages : 24 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis American Medical Isotopes Production Act of 2009 by : United States. Congress. House. Committee on Energy and Commerce

Download or read book American Medical Isotopes Production Act of 2009 written by United States. Congress. House. Committee on Energy and Commerce and published by . This book was released on 2009 with total page 24 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Radioactive Isotopes in Clinical Medicine and Research Xxiii

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 9783764359676
Total Pages : 880 pages
Book Rating : 4.3/5 (596 download)

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Book Synopsis Radioactive Isotopes in Clinical Medicine and Research Xxiii by : Helmar Bergmann

Download or read book Radioactive Isotopes in Clinical Medicine and Research Xxiii written by Helmar Bergmann and published by Springer Science & Business Media. This book was released on with total page 880 pages. Available in PDF, EPUB and Kindle. Book excerpt: