Mechanisms Of Memory

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Mechanisms of Memory

Author : J. David Sweatt
Publisher : Academic Press
ISBN 13 : 9780080959191
Total Pages : 362 pages
Book Rating : 4.9/5 (591 download)

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Book Synopsis Mechanisms of Memory by : J. David Sweatt

Download or read book Mechanisms of Memory written by J. David Sweatt and published by Academic Press. This book was released on 2009-09-28 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fully revised second edition provides the only unified synthesis of available information concerning the mechanisms of higher-order memory formation. It spans the range from learning theory, to human and animal behavioral learning models, to cellular physiology and biochemistry. It is unique in its incorporation of chapters on memory disorders, tying in these clinically important syndromes with the basic science of synaptic plasticity and memory mechanisms. It also covers cutting-edge approaches such as the use of genetically engineered animals in studies of memory and memory diseases. Written in an engaging and easily readable style and extensively illustrated with many new, full-color figures to help explain key concepts, this book demystifies the complexities of memory and deepens the reader’s understanding. More than 25% new content, particularly expanding the scope to include new findings in translational research. Unique in its depth of coverage of molecular and cellular mechanisms Extensive cross-referencing to Comprehensive Learning and Memory Discusses clinically relevant memory disorders in the context of modern molecular research and includes numerous practical examples

Neuronal Mechanisms of Memory Formation

Author : Christian Hölscher
Publisher : Cambridge University Press
ISBN 13 : 052177067X
Total Pages : 509 pages
Book Rating : 4.5/5 (217 download)

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Book Synopsis Neuronal Mechanisms of Memory Formation by : Christian Hölscher

Download or read book Neuronal Mechanisms of Memory Formation written by Christian Hölscher and published by Cambridge University Press. This book was released on 2001 with total page 509 pages. Available in PDF, EPUB and Kindle. Book excerpt: Long-term potentiation (LTP) is by far the most dominant model for neuronal changes that might encode memory. LTP is an elegant concept that meets many criteria set up by theoreticians long before the model's discovery, and it also fits anatomical data of learning-dependent synapse changes. Since the discovery of LTP, the question has remained about how closely LTP produced in vitro by artificial stimulation of neurons actually models putative learning-induced synaptic changes. A number of recent investigations have tried to correlate synaptic changes observed after learning with changes produced by artificial stimulation of neurons. These studies have failed to find a correlation between the two forms of synaptic plasticity. In this book, an international group of neurobiologists and psychologists discuss their latest ideas and data. The results of experiments using electrophysiological techniques in vitro are discussed and compared with the results of in vivo experiments. Learning experiments are also discussed. Theoretical models such as the Hebb theory of synaptic changes during learning are compared to different models that do not predict upregulation of synaptic transmission. A wide approach is taken, and research and models in different brain areas such as the neocortex and the basal brain are discussed.

Discovering the Brain

Author : National Academy of Sciences
Publisher : National Academies Press
ISBN 13 : 0309045290
Total Pages : 195 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Discovering the Brain by : National Academy of Sciences

Download or read book Discovering the Brain written by National Academy of Sciences and published by National Academies Press. This book was released on 1992-01-01 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain ... There is no other part of the human anatomy that is so intriguing. How does it develop and function and why does it sometimes, tragically, degenerate? The answers are complex. In Discovering the Brain, science writer Sandra Ackerman cuts through the complexity to bring this vital topic to the public. The 1990s were declared the "Decade of the Brain" by former President Bush, and the neuroscience community responded with a host of new investigations and conferences. Discovering the Brain is based on the Institute of Medicine conference, Decade of the Brain: Frontiers in Neuroscience and Brain Research. Discovering the Brain is a "field guide" to the brainâ€"an easy-to-read discussion of the brain's physical structure and where functions such as language and music appreciation lie. Ackerman examines: How electrical and chemical signals are conveyed in the brain. The mechanisms by which we see, hear, think, and pay attentionâ€"and how a "gut feeling" actually originates in the brain. Learning and memory retention, including parallels to computer memory and what they might tell us about our own mental capacity. Development of the brain throughout the life span, with a look at the aging brain. Ackerman provides an enlightening chapter on the connection between the brain's physical condition and various mental disorders and notes what progress can realistically be made toward the prevention and treatment of stroke and other ailments. Finally, she explores the potential for major advances during the "Decade of the Brain," with a look at medical imaging techniquesâ€"what various technologies can and cannot tell usâ€"and how the public and private sectors can contribute to continued advances in neuroscience. This highly readable volume will provide the public and policymakersâ€"and many scientists as wellâ€"with a helpful guide to understanding the many discoveries that are sure to be announced throughout the "Decade of the Brain."

Cognitive Neuroscience of Memory Consolidation

Author : Nikolai Axmacher
Publisher : Springer
ISBN 13 : 3319450662
Total Pages : 417 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Cognitive Neuroscience of Memory Consolidation by : Nikolai Axmacher

Download or read book Cognitive Neuroscience of Memory Consolidation written by Nikolai Axmacher and published by Springer. This book was released on 2017-02-09 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited volume provides an overview the state-of-the-art in the field of cognitive neuroscience of memory consolidation. In a number of sections, the editors collect contributions of leading researchers . The topical focus lies on current issues of interest such as memory consolidation including working and long-term memory. In particular, the role of sleep in relation to memory consolidation will be addressed. The target audience primarily comprises research experts in the field of cognitive neuroscience but the book may also be beneficial for graduate students.

Neural Plasticity and Memory

Author : Federico Bermudez-Rattoni
Publisher : CRC Press
ISBN 13 : 9781420008418
Total Pages : 368 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Neural Plasticity and Memory by : Federico Bermudez-Rattoni

Download or read book Neural Plasticity and Memory written by Federico Bermudez-Rattoni and published by CRC Press. This book was released on 2007-04-17 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive, multidisciplinary review, Neural Plasticity and Memory: From Genes to Brain Imaging provides an in-depth, up-to-date analysis of the study of the neurobiology of memory. Leading specialists share their scientific experience in the field, covering a wide range of topics where molecular, genetic, behavioral, and brain imaging techniques have been used to investigate how cellular and brain circuits may be modified by experience. In each chapter, researchers present findings and explain their innovative methodologies. The book begins by introducing key issues and providing a historical overview of the field of memory consolidation. The following chapters review the putative genetic and molecular mechanisms of cell plasticity, elaborating on how experience could induce gene and protein expression and describing their role in synaptic plasticity underlying memory formation. They explore how putative modifications of brain circuits and synaptic elements through experience can become relatively permanent and hence improve brain function. Interdisciplinary reviews focus on how nerve cell circuitry, molecular expression, neurotransmitter release, and electrical activity are modified during the acquisition and consolidation of long-term memory. The book also covers receptor activation/deactivation by different neurotransmitters that enable the intracellular activation of second messengers during memory formation. It concludes with a summary of current research on the modulation and regulation that different neurotransmitters and stress hormones have on formation and consolidation of memory.

Evolution of Learning and Memory Mechanisms

Author : Mark A. Krause
Publisher : Cambridge University Press
ISBN 13 : 1108853773
Total Pages : 521 pages
Book Rating : 4.1/5 (88 download)

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Book Synopsis Evolution of Learning and Memory Mechanisms by : Mark A. Krause

Download or read book Evolution of Learning and Memory Mechanisms written by Mark A. Krause and published by Cambridge University Press. This book was released on 2022-05-19 with total page 521 pages. Available in PDF, EPUB and Kindle. Book excerpt: Evolution of Learning and Memory Mechanisms is an exploration of laboratory and field research on the many ways that evolution has influenced learning and memory processes, such as associative learning, social learning, and spatial, working, and episodic memory systems. This volume features research by both outstanding early-career scientists as well as familiar luminaries in the field. Learning and memory in a broad range of animals are explored, including numerous species of invertebrates (insects, worms, sea hares), as well as fish, amphibians, birds, rodents, bears, and human and nonhuman primates. Contributors discuss how the behavioral, cognitive, and neural mechanisms underlying learning and memory have been influenced by evolutionary pressures. They also draw connections between learning and memory and the specific selective factors that shaped their evolution. Evolution of Learning and Memory Mechanisms should be a valuable resource for those working in the areas of experimental and comparative psychology, comparative cognition, brain–behavior evolution, and animal behavior.

Memory Mechanisms in Health and Disease

Author : Karl Peter Giese
Publisher : World Scientific
ISBN 13 : 9814458147
Total Pages : 460 pages
Book Rating : 4.8/5 (144 download)

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Book Synopsis Memory Mechanisms in Health and Disease by : Karl Peter Giese

Download or read book Memory Mechanisms in Health and Disease written by Karl Peter Giese and published by World Scientific. This book was released on 2012-06-07 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: Memory Mechanisms is an edited review volume that summarizes state-of-the-art knowledge on memory mechanisms at the molecular, cellular and circuit level. Each review is written by leading experts in the field, presenting not only current knowledge, but also discussing the concepts, providing critical reflections and suggesting an outlook for future studies. The memory mechanisms are also discussed in the context of diseases. Studies of memory deficits in disease models are introduced as well as approaches to restore memory deficits. Finally, the impact of contemporary memory research for psychiatry is illustrated. Contents:Introduction (Karl Peter Giese)Long-term Potentiation and Memory (Karl Peter Giese)Structural Synaptic and Dendritic Spine Plasticity in the Hippocampus (Michael G Stewart and Victor I Popov)Memory Beyond Synaptic Plasticity: The Role of Intrinsic Neuronal Excitability (Athanasia Papoutsi, Kyriaki Sidiropoulou and Panayiota Poirazi)Adult Hippocampal Neurogenesis and Memory (Scellig S D Stone and Paul W Frankland)Memory Consolidation and Its Underlying Mechanisms (Cristina M Alberini, Dhananjay Bambah-Mukku and Dillon Y Chen)The Role of CREB and CREB Co-activators in Memory Formation (Melanie J Sekeres, Derya Sargin, P Joel Ross and Sheena A Josselyn)Sex Differences in Memory Formation (Keiko Mizuno and Karl Peter Giese)Neocortical Learning, Memory and Experience-dependent Plasticity (Giorgia Albieri and Gerald T Finnerty)Mechanisms of Memory Storage (Kimberly Lackenby and Karl Peter Giese)Memory Reconsolidation and Extinction (Satoshi Kida)Memory Circuits in Drosophila (Katsuo Furukubo-Tokunaga, Zoe N Ludlow and Frank Hirth)Memory Circuits in the Hippocampus (Thomas J McHugh)Impaired Memory Mechanisms in Mouse Models of Alzheimer's Disease (Masuo Ohno)Restoring Memory Deficits in Cognitive Diseases (Andre Fischer)The Impact of Studies of Memory Mechanisms for Psychiatry (Shahid H Zaman) Readership: Students and professionals interested in neurology/neuroscience. Keywords:Brain;Learning;Mental Health;Memory;Neuronal Networks;Plasticity;SignallingKey Features:The book provides a comprehensive overview on mechanisms of memoryThe book is useful for organizing undergraduate courses and for the teaching of medical studentsIt complements more basic text books such as “Mechanisms of Memory” by JD Sweatt, Academic Press, 2009, and it provides insights into memory dysfunction in diseases and routes for treating such deficits

Mechanisms of Sensory Working Memory

Author : Pierre Jolicoeur
Publisher : Elsevier
ISBN 13 : 0128110430
Total Pages : 312 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Mechanisms of Sensory Working Memory by : Pierre Jolicoeur

Download or read book Mechanisms of Sensory Working Memory written by Pierre Jolicoeur and published by Elsevier. This book was released on 2016-06-17 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mechanisms of Sensory Working Memory: Attention and Performance XXV provides an update on research surrounding the memory processes that are crucial for many facets of cognitive processing and experience, with new coverage of emerging areas of study, including a new understanding of working memory for features of stimuli devoid of verbal, phonological, or long-term memory content, such as memory for simple visual features (e.g., texture or color), simple auditory features (e.g., pitch), or simple tactile features (e.g., vibration frequency), now called sensory memory to distinguish from verbal memory. This contemporary focus on sensory memory is just beginning, and this collection of original contributions provides a foundational reference for the study mechanisms of sensory memory. Students, scholars, and researchers studying memory mechanisms and processes in cognitive neuroscience, cognitive science, neuroscience, and psychology will find this book of great value to their work. Introduces the study of sensory mechanisms of working memory as distinct from verbal memory Covers visual memory, auditory memory, and tactile memory Includes translational content as the breakdown of working memory is often associated with a disease, disorder, or trauma to the brain

How We Remember

Author : Michael E. Hasselmo
Publisher : MIT Press
ISBN 13 : 026252533X
Total Pages : 383 pages
Book Rating : 4.2/5 (625 download)

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Book Synopsis How We Remember by : Michael E. Hasselmo

Download or read book How We Remember written by Michael E. Hasselmo and published by MIT Press. This book was released on 2013-08-16 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: A novel perspective on the biological mechanisms of episodic memory, focusing on the encoding and retrieval of spatiotemporal trajectories. Episodic memory proves essential for daily function, allowing us to remember where we parked the car, what time we walked the dog, or what a friend said earlier. In How We Remember, Michael Hasselmo draws on recent developments in neuroscience to present a new model describing the brain mechanisms for encoding and remembering such events as spatiotemporal trajectories. He reviews physiological breakthroughs on the regions implicated in episodic memory, including the discovery of grid cells, the cellular mechanisms of persistent spiking and resonant frequency, and the topographic coding of space and time. These discoveries inspire a theory for understanding the encoding and retrieval of episodic memory not just as discrete snapshots but as a dynamic replay of spatiotemporal trajectories, allowing us to "retrace our steps" to recover a memory. In the main text of the book, he presents the model in narrative form, accessible to scholars and advanced undergraduates in many fields. In the appendix, he presents the material in a more quantitative style, providing mathematical descriptions appropriate for advanced undergraduates and graduate students in neuroscience or engineering.

Identification of Neural Markers Accompanying Memory

Author : Alfredo Meneses
Publisher : Elsevier
ISBN 13 : 012416711X
Total Pages : 169 pages
Book Rating : 4.1/5 (241 download)

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Book Synopsis Identification of Neural Markers Accompanying Memory by : Alfredo Meneses

Download or read book Identification of Neural Markers Accompanying Memory written by Alfredo Meneses and published by Elsevier. This book was released on 2013-11-23 with total page 169 pages. Available in PDF, EPUB and Kindle. Book excerpt: Identification of Neural Markers Accompanying Memory is a fresh and novel volume of memory study, providing up-to-date and comprehensive information for both students and researchers focused on the identification of neural markers accompanying memory. Contributions by experts in specific areas of memory study provide background on and definitions of memory, memory alterations, and the brain areas involved in memory and its related processes, such as consolidation, retrieval, forgetting, amnesia, and antiamnesiac effects. With coverage of the principal neurotransmitters related to memory, brain disorders presenting memory alterations, and available treatments—and with discussion of neural markers as new targets for the treatment of memory alterations—Identification of Neural Markers Accompanying Memory is a necessary and timely work for researchers in this growing field. Discusses the alterations of memory in diverse diseases Includes coverage from a basic introduction of memory investigation Reviews brain areas and neurotransmitters involved in memory Discusses behavioral models of memory Contains novel insights into the complexity of signaling and memory Includes the neuropharmacological and neurobiological bases of memory

Biology of Memory

Author : Karl Pribram
Publisher : Elsevier
ISBN 13 : 0323141501
Total Pages : 337 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Biology of Memory by : Karl Pribram

Download or read book Biology of Memory written by Karl Pribram and published by Elsevier. This book was released on 2012-12-02 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biology of Memory investigates the biological basis of memory and covers topics ranging from short- and long-term post-perceptual memory to memory storage processes, memory microstructures, chemical transfer, and neuronal plasticity. The activity of neuronal networks in the thalamus of the monkey is also examined, along with integrative functions of the thalamocortical visual system of the cat. Comprised of 20 chapters, this book begins with an overview of the mechanisms that inhibit or interfere with short- and long-term memory, followed by a discussion on different retrieval mechanisms for short- and long-term memory. The reader is then introduced to the role of short- and long-term memory in the formation, retention, and utilization of associations, together with the link between memory and the medial temporal regions of the brain. Subsequent chapters focus on anatomical and chemical changes in the brain during primary learning; cellular models of learning and cellular mechanisms of plasticity in Aplysia; trace phenomena in single neurons of hippocampus and mammiliary bodies; and plasticity in single units in the mammalian brain. The book concludes with a description of Occam (Omnium-Gatherum Core Content Addressable Memory), a computer program for a content addressable memory in the central nervous system. This monograph will be useful to biologists, behavioral psychologists, neuropsychologists, neurophysiologists, biophysicists, and biochemists as well as computer scientists and mathematicians.

The Oxford Handbook of Memory

Author : Endel Tulving
Publisher : Oxford University Press
ISBN 13 : 0190292865
Total Pages : 720 pages
Book Rating : 4.1/5 (92 download)

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Book Synopsis The Oxford Handbook of Memory by : Endel Tulving

Download or read book The Oxford Handbook of Memory written by Endel Tulving and published by Oxford University Press. This book was released on 2005-05-05 with total page 720 pages. Available in PDF, EPUB and Kindle. Book excerpt: The strengths and weaknesses of human memory have fascinated people for hundreds of years, so it is not surprising that memory research has remained one of the most flourishing areas in science. During the last decade, however, a genuine science of memory has emerged, resulting in research and theories that are rich, complex, and far reaching in their implications. Endel Tulving and Fergus Craik, both leaders in memory research, have created this highly accessible guide to their field. In each chapter, eminent researchers provide insights into their particular areas of expertise in memory research. Together, the chapters in this handbook lay out the theories and presents the evidence on which they are based, highlights the important new discoveries, and defines their consequences for professionals and students in psychology, neuroscience, clinical medicine, law, and engineering.

The Seven Sins of Memory

Author : Daniel L. Schacter
Publisher : HMH
ISBN 13 : 0547347456
Total Pages : 289 pages
Book Rating : 4.5/5 (473 download)

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Book Synopsis The Seven Sins of Memory by : Daniel L. Schacter

Download or read book The Seven Sins of Memory written by Daniel L. Schacter and published by HMH. This book was released on 2002-05-07 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: A New York Times Notable Book: A psychologist’s “gripping and thought-provoking” look at how and why our brains sometimes fail us (Steven Pinker, author of How the Mind Works). In this intriguing study, Harvard psychologist Daniel L. Schacter explores the memory miscues that occur in everyday life, placing them into seven categories: absent-mindedness, transience, blocking, misattribution, suggestibility, bias, and persistence. Illustrating these concepts with vivid examples—case studies, literary excerpts, experimental evidence, and accounts of highly visible news events such as the O. J. Simpson verdict, Bill Clinton’s grand jury testimony, and the search for the Oklahoma City bomber—he also delves into striking new scientific research, giving us a glimpse of the fascinating neurology of memory and offering “insight into common malfunctions of the mind” (USA Today). “Though memory failure can amount to little more than a mild annoyance, the consequences of misattribution in eyewitness testimony can be devastating, as can the consequences of suggestibility among pre-school children and among adults with ‘false memory syndrome’ . . . Drawing upon recent neuroimaging research that allows a glimpse of the brain as it learns and remembers, Schacter guides his readers on a fascinating journey of the human mind.” —Library Journal “Clear, entertaining and provocative . . . Encourages a new appreciation of the complexity and fragility of memory.” —The Seattle Times “Should be required reading for police, lawyers, psychologists, and anyone else who wants to understand how memory can go terribly wrong.” —The Atlanta Journal-Constitution “A fascinating journey through paths of memory, its open avenues and blind alleys . . . Lucid, engaging, and enjoyable.” —Jerome Groopman, MD “Compelling in its science and its probing examination of everyday life, The Seven Sins of Memory is also a delightful book, lively and clear.” —Chicago Tribune Winner of the William James Book Award

Behavioral Neuroscience of Learning and Memory

Author : Robert E. Clark
Publisher : Springer
ISBN 13 : 3319787578
Total Pages : 359 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis Behavioral Neuroscience of Learning and Memory by : Robert E. Clark

Download or read book Behavioral Neuroscience of Learning and Memory written by Robert E. Clark and published by Springer. This book was released on 2018-03-27 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt: ‘Behavioral Neuroscience of Learning and Memory’ brings together the opinions and expertise of some of the world’s foremost neuroscientists in the field of learning and memory research. The volume provides a broad coverage of contemporary research and thinking in this field, focusing both on well established topics such as the medial temporal lobe memory system, as well as emerging areas of research such as the role of memory in decision making and the mechanisms of perceptual learning. Key intersecting themes include the molecular and cellular mechanisms of memory formation, the multiplicity of memory systems in the brain, and the way in which technological innovation is driving discovery. Unusually for a volume of this kind, this volume brings together research from both humans and animals—often relatively separate areas of discourse—to give a more comprehensive and integrated view of the field. The book will be of interest to both established researchers who wish to broaden their knowledge of topics outside of their specific areas of expertise, and for students who need a resource to help them make sense of the vast scientific literature on this subject.

The Student's Guide to Cognitive Neuroscience

Author : Jamie Ward
Publisher : Psychology Press
ISBN 13 : 1317586018
Total Pages : 549 pages
Book Rating : 4.3/5 (175 download)

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Book Synopsis The Student's Guide to Cognitive Neuroscience by : Jamie Ward

Download or read book The Student's Guide to Cognitive Neuroscience written by Jamie Ward and published by Psychology Press. This book was released on 2015-02-11 with total page 549 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reflecting recent changes in the way cognition and the brain are studied, this thoroughly updated third edition of the best-selling textbook provides a comprehensive and student-friendly guide to cognitive neuroscience. Jamie Ward provides an easy-to-follow introduction to neural structure and function, as well as all the key methods and procedures of cognitive neuroscience, with a view to helping students understand how they can be used to shed light on the neural basis of cognition. The book presents an up-to-date overview of the latest theories and findings in all the key topics in cognitive neuroscience, including vision, memory, speech and language, hearing, numeracy, executive function, social and emotional behaviour and developmental neuroscience, as well as a new chapter on attention. Throughout, case studies, newspaper reports and everyday examples are used to help students understand the more challenging ideas that underpin the subject. In addition each chapter includes: Summaries of key terms and points Example essay questions Recommended further reading Feature boxes exploring interesting and popular questions and their implications for the subject. Written in an engaging style by a leading researcher in the field, and presented in full-color including numerous illustrative materials, this book will be invaluable as a core text for undergraduate modules in cognitive neuroscience. It can also be used as a key text on courses in cognition, cognitive neuropsychology, biopsychology or brain and behavior. Those embarking on research will find it an invaluable starting point and reference. The Student’s Guide to Cognitive Neuroscience, 3rd Edition is supported by a companion website, featuring helpful resources for both students and instructors.

Models of Working Memory

Author : Akira Miyake
Publisher : Cambridge University Press
ISBN 13 : 9780521587211
Total Pages : 532 pages
Book Rating : 4.5/5 (872 download)

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Book Synopsis Models of Working Memory by : Akira Miyake

Download or read book Models of Working Memory written by Akira Miyake and published by Cambridge University Press. This book was released on 1999-04-13 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume offers a much-needed forum for comparing and contrasting existing models of working memory.

Drebrin

Author : Tomoaki Shirao
Publisher : Springer
ISBN 13 : 4431565507
Total Pages : 401 pages
Book Rating : 4.4/5 (315 download)

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Book Synopsis Drebrin by : Tomoaki Shirao

Download or read book Drebrin written by Tomoaki Shirao and published by Springer. This book was released on 2017-08-31 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the first comprehensive review of drebrin, which plays pivotal roles in various cellular events, via forming unique actin cytoskeletons, including synapse formation and in synaptic function. Particularly the loss of drebrin from dendritic spines is used as a marker of dementia in neurological disorders such as Alzheimer’s disease. Since drebrin was first identified by our group in 1985, many studies of drebrin have been done in various fields, including not only molecular biology, biophysics, cell biology, neuroscience, clinical studies, spermatogenesis, immunology, and cancer metastasis, but others as well. The structure of this book facilitates the understanding of the whole picture of studies on drebrin. The volume begins with a general introduction to drebrin, and then the chapters in the second part provide the basic knowledge for further understanding. The third part examines its function in the nervous system, and the fourth part discusses its function in the non-nervous system. This work will appeal to researchers who are interested in cytoskeletal dynamics at membrane-cytoskeletal interface as well as the number of them who use drebrin as a tool, such as a marker of synaptic function or a disease marker. This volume is kept as concise as possible in order to be understood by readers in diverse scientific disciplines.