Mechanical Models Of Proteins

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Protein Actions: Principles and Modeling

Author : Ivet Bahar
Publisher : Garland Science
ISBN 13 : 1351815016
Total Pages : 337 pages
Book Rating : 4.3/5 (518 download)

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Book Synopsis Protein Actions: Principles and Modeling by : Ivet Bahar

Download or read book Protein Actions: Principles and Modeling written by Ivet Bahar and published by Garland Science. This book was released on 2017-02-14 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: Protein Actions: Principles and Modeling is aimed at graduates, advanced undergraduates, and any professional who seeks an introduction to the biological, chemical, and physical properties of proteins. Broadly accessible to biophysicists and biochemists, it will be particularly useful to student and professional structural biologists and molecular biophysicists, bioinformaticians and computational biologists, biological chemists (particularly drug designers) and molecular bioengineers. The book begins by introducing the basic principles of protein structure and function. Some readers will be familiar with aspects of this, but the authors build up a more quantitative approach than their competitors. Emphasizing concepts and theory rather than experimental techniques, the book shows how proteins can be analyzed using the disciplines of elementary statistical mechanics, energetics, and kinetics. These chapters illuminate how proteins attain biologically active states and the properties of those states. The book ends with a synopsis the roles of computational biology and bioinformatics in protein science.

Statistical Mechanics, Protein Structure, and Protein Substrate Interactions

Author : Sebastian Doniach
Publisher : Springer
ISBN 13 : 9781489913517
Total Pages : 406 pages
Book Rating : 4.9/5 (135 download)

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Book Synopsis Statistical Mechanics, Protein Structure, and Protein Substrate Interactions by : Sebastian Doniach

Download or read book Statistical Mechanics, Protein Structure, and Protein Substrate Interactions written by Sebastian Doniach and published by Springer. This book was released on 2013-06-19 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: A number of factors have come together in the last couple of decades to define the emerging interdisciplinary field of structural molecular biology. First, there has been the considerable growth in our ability to obtain atomic-resolution structural data for biological molecules in general, and proteins in particular. This is a result of advances in technique, both in x-ray crystallography, driven by the development of electronic detectors and of synchrotron radiation x-ray sources, and by the development ofNMR techniques which allow for inference of a three-dimensional structure of a protein in solution. Second, there has been the enormous development of techniques in DNA engineering which makes it possible to isolate and clone specific molecules of interest in sufficient quantities to enable structural measurements. In addition, the ability to mutate a given amino acid sequence at will has led to a new branch of biochemistry in which quantitative measurements can be made assessing the influence of a given amino acid on the function of a biological molecule. A third factor, resulting from the exponential increase in computing power available to researchers, has been the emergence of a growing body of people who can take the structural data and use it to build atomic-scale models of biomolecules in order to try and simulate their motions in an aqueous environment, thus helping to provide answers to one of the most basic questions of molecular biology: the relation of structure to function.

Statistical Mechanics, Protein Structure, and Protein Substrate Interactions

Author : Sebastian Doniach
Publisher : Springer Science & Business Media
ISBN 13 : 1489913491
Total Pages : 400 pages
Book Rating : 4.4/5 (899 download)

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Book Synopsis Statistical Mechanics, Protein Structure, and Protein Substrate Interactions by : Sebastian Doniach

Download or read book Statistical Mechanics, Protein Structure, and Protein Substrate Interactions written by Sebastian Doniach and published by Springer Science & Business Media. This book was released on 2013-11-22 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: A number of factors have come together in the last couple of decades to define the emerging interdisciplinary field of structural molecular biology. First, there has been the considerable growth in our ability to obtain atomic-resolution structural data for biological molecules in general, and proteins in particular. This is a result of advances in technique, both in x-ray crystallography, driven by the development of electronic detectors and of synchrotron radiation x-ray sources, and by the development ofNMR techniques which allow for inference of a three-dimensional structure of a protein in solution. Second, there has been the enormous development of techniques in DNA engineering which makes it possible to isolate and clone specific molecules of interest in sufficient quantities to enable structural measurements. In addition, the ability to mutate a given amino acid sequence at will has led to a new branch of biochemistry in which quantitative measurements can be made assessing the influence of a given amino acid on the function of a biological molecule. A third factor, resulting from the exponential increase in computing power available to researchers, has been the emergence of a growing body of people who can take the structural data and use it to build atomic-scale models of biomolecules in order to try and simulate their motions in an aqueous environment, thus helping to provide answers to one of the most basic questions of molecular biology: the relation of structure to function.

Advances in Chemical Physics, Volume 46

Author : Ilya Prigogine
Publisher : John Wiley & Sons
ISBN 13 : 0470143118
Total Pages : 442 pages
Book Rating : 4.4/5 (71 download)

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Book Synopsis Advances in Chemical Physics, Volume 46 by : Ilya Prigogine

Download or read book Advances in Chemical Physics, Volume 46 written by Ilya Prigogine and published by John Wiley & Sons. This book was released on 2009-09-08 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Advances in Chemical Physics series provides the chemical physics and physical chemistry fields with a forum for critical, authoritative evaluations of advances in every area of the discipline. Filled with cutting-edge research reported in a cohesive manner not found elsewhere in the literature, each volume of the Advances in Chemical Physics series serves as the perfect supplement to any advanced graduate class devoted to the study of chemical physics.

Molecular Modeling of Proteins

Author : Andreas Kukol
Publisher : Humana Press
ISBN 13 : 9781493954919
Total Pages : 474 pages
Book Rating : 4.9/5 (549 download)

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Book Synopsis Molecular Modeling of Proteins by : Andreas Kukol

Download or read book Molecular Modeling of Proteins written by Andreas Kukol and published by Humana Press. This book was released on 2017-04-30 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Modeling of Proteins, Second Edition provides a theoretical background of various methods available and enables non-specialists to apply methods to their problems by including updated chapters and new material not covered in the first edition. This detailed volume opens by featuring classical and advanced simulation methods as well as methods to set-up complex systems such as lipid membranes and membrane proteins and continues with chapters devoted to the simulation and analysis of conformational changes of proteins, computational methods for protein structure prediction, usage of experimental data in combination with computational techniques, as well as protein-ligand interactions, which are relevant in the drug design process. Written for the highly successful Methods in Molecular Biology series, chapters include thorough introductions, step-by-step instructions and notes on troubleshooting and avoiding common pitfalls. Update-to-date and authoritative, Molecular Modeling of Proteins, Second Edition aims to aid researchers in the physical, chemical and biosciences interested in utilizing this powerful technology.

Mechanics of Motor Proteins and the Cytoskeleton

Author : Jonathon Howard
Publisher : Sinauer
ISBN 13 : 9780878933334
Total Pages : 0 pages
Book Rating : 4.9/5 (333 download)

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Book Synopsis Mechanics of Motor Proteins and the Cytoskeleton by : Jonathon Howard

Download or read book Mechanics of Motor Proteins and the Cytoskeleton written by Jonathon Howard and published by Sinauer. This book was released on 2005-12-06 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mechanics of Motor Proteins and the Cytoskeleton provides a physical foundation for molecular mechanics. Part I explains how small particles like proteins respond to mechanical, thermal, and chemical forces, Part II focuses on cytoskeletal filaments, and Part III focuses on motor proteins. The treatments are unified in the respect that they are organized around principles rather than proteins: chapters are centred on topics such as structure, chemistry, and mechanics, and different filaments or motors are discussed together.

Protein Modelling

Author : Andrew Gamble
Publisher : Springer
ISBN 13 : 3319099760
Total Pages : 332 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis Protein Modelling by : Andrew Gamble

Download or read book Protein Modelling written by Andrew Gamble and published by Springer. This book was released on 2014-11-13 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this volume, a detailed description of cutting-edge computational methods applied to protein modeling as well as specific applications are presented. Chapters include: the application of Car-Parrinello techniques to enzyme mechanisms, the outline and application of QM/MM methods, polarizable force fields, recent methods of ligand docking, molecular dynamics related to NMR spectroscopy, computer optimization of absorption, distribution, metabolism and excretion extended by toxicity for drugs, enzyme design and bioinformatics applied to protein structure prediction. A keen emphasis is laid on the clear presentation of complex concepts, since the book is primarily aimed at Ph.D. students, who need an insight in up-to-date protein modeling. The inclusion of descriptive, color figures will allow the reader to get a pictorial representation of complicated structural issues.

Molecular Biology of the Cell

Author :
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of the Cell by :

Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Advanced Techniques in Biophysics

Author : José Luis R. Arrondo
Publisher : Springer Science & Business Media
ISBN 13 : 3540307869
Total Pages : 290 pages
Book Rating : 4.5/5 (43 download)

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Book Synopsis Advanced Techniques in Biophysics by : José Luis R. Arrondo

Download or read book Advanced Techniques in Biophysics written by José Luis R. Arrondo and published by Springer Science & Business Media. This book was released on 2007-04-21 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Technical advancements are basic elements in our life. In biophysical studies, new applications and improvements in well-established techniques are being implemented every day. This book deals with advancements produced not only from a technical point of view, but also from new approaches that are being taken in the study of biophysical samples, such as nanotechniques or single-cell measurements. This book constitutes a privileged observatory for reviewing novel applications of biophysical techniques that can help the reader enter an area where the technology is progressing quickly and where a comprehensive explanation is not always to be found.

Theoretical and Applied Mechanics

Author : Mario Di Paola
Publisher : Materials Research Forum LLC
ISBN 13 : 1644902435
Total Pages : 746 pages
Book Rating : 4.6/5 (449 download)

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Book Synopsis Theoretical and Applied Mechanics by : Mario Di Paola

Download or read book Theoretical and Applied Mechanics written by Mario Di Paola and published by Materials Research Forum LLC. This book was released on 2023-04-25 with total page 746 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book presents the proceedings of the XXV National Congress of the Italian Association of Theoretical and Applied Mechanics (Palermo, September 2022). The topics cover theoretical, computational, experimental and technical-applicative aspects. Chapters: Fluid Mechanics, Solid Mechanics, Structural Mechanics, Mechanics of Machine, Computational Mechanics, Biomechanics, Masonry Modelling and Analysis, Dynamical Systems in Civil and Mechanical Structures, Control and Experimental Dynamics, Mechanical Modelling of Metamaterials and Periodic Structures, Novel Stochastic Dynamics, Signal Processing Techniques for Civil Engineering Applications, Vibration-based Monitoring and Dynamic Identification of Historic Constructions, Modeling and Analysis of Nanocomposites and Small-Scale Structures, Gradient Flows in Mechanics and Continuum Physics, Multibody Systems Vibration Analysis, Mechanics of Renewable Energy Systems, Mathematical Modeling and Experimental Techniques for Quantification and Prediction of Fluid Dynamic Noise, and Advanced Process Mechanics. Keywords: Fluid Mechanics, Solid Mechanics, Structural Mechanics, Mechanics of Machine, Computational Mechanics, Biomechanics, Masonry Modelling and Analysis, Dynamical Systems in Civil and Mechanical Structures, Control and Experimental Dynamics, Mechanical Modelling of Metamaterials and Periodic Structures, Novel Stochastic Dynamics, Signal Processing Techniques for Civil Engineering Applications, Vibration-based Monitoring and Dynamic Identification of Historic Constructions, Modeling and Analysis of Nanocomposites and Small-Scale Structures, Gradient Flows in Mechanics and Continuum Physics, Multibody Systems Vibration Analysis, Mechanics of Renewable Energy Systems, Mathematical Modeling and Experimental Techniques for Quantification and Prediction of Fluid Dynamic Noise, and Advanced Process Mechanics.

Multiscale Approaches to Protein Modeling

Author : Andrzej Kolinski
Publisher : Springer Science & Business Media
ISBN 13 : 144196889X
Total Pages : 360 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Multiscale Approaches to Protein Modeling by : Andrzej Kolinski

Download or read book Multiscale Approaches to Protein Modeling written by Andrzej Kolinski and published by Springer Science & Business Media. This book was released on 2010-10-13 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book gives a comprehensive review of the most advanced multiscale methods for protein structure prediction, computational studies of protein dynamics, folding mechanisms and macromolecular interactions. It approaches span a wide range of the levels of coarse-grained representations, various sampling techniques and variety of applications to biomedical and biophysical problems. This book is intended to be used as a reference book for those who are just beginning their adventure with biomacromolecular modeling but also as a valuable source of detailed information for those who are already experts in the field of biomacromolecular modeling and in related areas of computational biology or biophysics.

Protein Structure

Author : Eshel Faraggi
Publisher : BoD – Books on Demand
ISBN 13 : 9535105558
Total Pages : 412 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Protein Structure by : Eshel Faraggi

Download or read book Protein Structure written by Eshel Faraggi and published by BoD – Books on Demand. This book was released on 2012-04-20 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the dawn of recorded history, and probably even before, men and women have been grasping at the mechanisms by which they themselves exist. Only relatively recently, did this grasp yield anything of substance, and only within the last several decades did the proteins play a pivotal role in this existence. In this expose on the topic of protein structure some of the current issues in this scientific field are discussed. The aim is that a non-expert can gain some appreciation for the intricacies involved, and in the current state of affairs. The expert meanwhile, we hope, can gain a deeper understanding of the topic.

Protein Structure

Author : Daniel Chasman
Publisher : CRC Press
ISBN 13 : 1135544050
Total Pages : 612 pages
Book Rating : 4.1/5 (355 download)

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Book Synopsis Protein Structure by : Daniel Chasman

Download or read book Protein Structure written by Daniel Chasman and published by CRC Press. This book was released on 2003-03-18 with total page 612 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text offers in-depth perspectives on every aspect of protein structure identification, assessment, characterization, and utilization, for a clear understanding of the diversity of protein shapes, variations in protein function, and structure-based drug design. The authors cover numerous high-throughput technologies as well as computational met

Functional Imaging and Modeling of the Heart

Author : Isabelle E. Magnin
Publisher : Springer Science & Business Media
ISBN 13 : 3540402624
Total Pages : 319 pages
Book Rating : 4.5/5 (44 download)

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Book Synopsis Functional Imaging and Modeling of the Heart by : Isabelle E. Magnin

Download or read book Functional Imaging and Modeling of the Heart written by Isabelle E. Magnin and published by Springer Science & Business Media. This book was released on 2003-05-22 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: The refereed proceedings of the Second International Workshop on Functional Imaging and Modeling of the Heart, FIMH 2003, held in Lyon, France in June 2003. The 29 revised full papers presented together with 2 invited papers were carefully reviewed and selected for presentation. The papers are organized in topical sections on anatomy extraction and description, modeling of the cardiac mechanics and functions, electro-physiology and electro- and magnetography, motion estimation, image registration and image analysis, and data acquisition and experimental and modeling issues.

Protein Folds

Author : Henrik Bohr
Publisher : CRC Press
ISBN 13 : 9780849340093
Total Pages : 352 pages
Book Rating : 4.3/5 (4 download)

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Book Synopsis Protein Folds by : Henrik Bohr

Download or read book Protein Folds written by Henrik Bohr and published by CRC Press. This book was released on 1995-10-20 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by outstanding scientists in physics and molecular biology, this book addresses the most recent advances in the analysis of the protein folding processes and protein structure determination. Emphasis is also placed on modelling and presentation of experimental results of structural membrane bound proteins. Many color plates help to illustrate structural aspects covered including: Defining folds of protein domains Structure determination from sequence Distance geometry Lattice theories Membrane proteins Protein-Ligand interaction Topological considerations Docking onto receptors All analysis is presented with proven theory and experimentation. Protein Folds: A Distance-Based Approach is an excellent text/reference for biotechnologists and biochemists as well as graduate students studying in the research sciences.

Biological Sequence Analysis

Author : Richard Durbin
Publisher : Cambridge University Press
ISBN 13 : 113945739X
Total Pages : 372 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Biological Sequence Analysis by : Richard Durbin

Download or read book Biological Sequence Analysis written by Richard Durbin and published by Cambridge University Press. This book was released on 1998-04-23 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Probabilistic models are becoming increasingly important in analysing the huge amount of data being produced by large-scale DNA-sequencing efforts such as the Human Genome Project. For example, hidden Markov models are used for analysing biological sequences, linguistic-grammar-based probabilistic models for identifying RNA secondary structure, and probabilistic evolutionary models for inferring phylogenies of sequences from different organisms. This book gives a unified, up-to-date and self-contained account, with a Bayesian slant, of such methods, and more generally to probabilistic methods of sequence analysis. Written by an interdisciplinary team of authors, it aims to be accessible to molecular biologists, computer scientists, and mathematicians with no formal knowledge of the other fields, and at the same time present the state-of-the-art in this new and highly important field.

Artificial Protein and Peptide Nanofibers

Author : Gang Wei
Publisher : Woodhead Publishing
ISBN 13 : 0081028512
Total Pages : 504 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Artificial Protein and Peptide Nanofibers by : Gang Wei

Download or read book Artificial Protein and Peptide Nanofibers written by Gang Wei and published by Woodhead Publishing. This book was released on 2020-07-28 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Artificial Protein and Peptide Nanofibers: Design, Fabrication, Characterization, and Applications provides comprehensive knowledge of the preparation, modification and applications of protein and peptide nanofibers. The book reviews the synthesis and strategies necessary to create protein and peptide nanofibers, such as self-assembly (including supramolecular assembly), electrospinning, template synthesis, and enzymatic synthesis. Then, the key chemical modification and molecular design methods are highlighted that can be utilized to improve the bio-functions of these synthetic fibers. Finally, fabrication methods for key applications, such as sensing, drug delivery, imaging, tissue engineering and electronic devices are reviewed. This book will be an ideal resource for those working in materials science, polymer science, chemical engineering, nanotechnology and biomedicine. - Reviews key chemical modification and molecular design methods to improve the bio-functions of synthetic peptide and protein nanofibers - Discusses the most important synthesis strategies, including supramolecular assembly, electrospinning, template synthesis and enzymatic synthesis - Provides information on fabrication of nanofibers for key applications such as sensing, imaging, drug delivery and tissue engineering