Mathematical Modeling in Systems Biology

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Publisher : MIT Press
ISBN 13 : 0262545829
Total Pages : 423 pages
Book Rating : 4.2/5 (625 download)

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Book Synopsis Mathematical Modeling in Systems Biology by : Brian P. Ingalls

Download or read book Mathematical Modeling in Systems Biology written by Brian P. Ingalls and published by MIT Press. This book was released on 2022-06-07 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: An introduction to the mathematical concepts and techniques needed for the construction and analysis of models in molecular systems biology. Systems techniques are integral to current research in molecular cell biology, and system-level investigations are often accompanied by mathematical models. These models serve as working hypotheses: they help us to understand and predict the behavior of complex systems. This book offers an introduction to mathematical concepts and techniques needed for the construction and interpretation of models in molecular systems biology. It is accessible to upper-level undergraduate or graduate students in life science or engineering who have some familiarity with calculus, and will be a useful reference for researchers at all levels. The first four chapters cover the basics of mathematical modeling in molecular systems biology. The last four chapters address specific biological domains, treating modeling of metabolic networks, of signal transduction pathways, of gene regulatory networks, and of electrophysiology and neuronal action potentials. Chapters 3–8 end with optional sections that address more specialized modeling topics. Exercises, solvable with pen-and-paper calculations, appear throughout the text to encourage interaction with the mathematical techniques. More involved end-of-chapter problem sets require computational software. Appendixes provide a review of basic concepts of molecular biology, additional mathematical background material, and tutorials for two computational software packages (XPPAUT and MATLAB) that can be used for model simulation and analysis.

An Introduction to Mathematical Modeling

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Author :
Publisher : Courier Corporation
ISBN 13 : 0486137120
Total Pages : 273 pages
Book Rating : 4.4/5 (861 download)

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Book Synopsis An Introduction to Mathematical Modeling by : Edward A. Bender

Download or read book An Introduction to Mathematical Modeling written by Edward A. Bender and published by Courier Corporation. This book was released on 2012-05-23 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: Employing a practical, "learn by doing" approach, this first-rate text fosters the development of the skills beyond the pure mathematics needed to set up and manipulate mathematical models. The author draws on a diversity of fields — including science, engineering, and operations research — to provide over 100 reality-based examples. Students learn from the examples by applying mathematical methods to formulate, analyze, and criticize models. Extensive documentation, consisting of over 150 references, supplements the models, encouraging further research on models of particular interest. The lively and accessible text requires only minimal scientific background. Designed for senior college or beginning graduate-level students, it assumes only elementary calculus and basic probability theory for the first part, and ordinary differential equations and continuous probability for the second section. All problems require students to study and create models, encouraging their active participation rather than a mechanical approach. Beyond the classroom, this volume will prove interesting and rewarding to anyone concerned with the development of mathematical models or the application of modeling to problem solving in a wide array of applications.

Modeling Life

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Publisher : Springer
ISBN 13 : 3319597310
Total Pages : 456 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Modeling Life by : Alan Garfinkel

Download or read book Modeling Life written by Alan Garfinkel and published by Springer. This book was released on 2017-09-06 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book develops the mathematical tools essential for students in the life sciences to describe interacting systems and predict their behavior. From predator-prey populations in an ecosystem, to hormone regulation within the body, the natural world abounds in dynamical systems that affect us profoundly. Complex feedback relations and counter-intuitive responses are common in nature; this book develops the quantitative skills needed to explore these interactions. Differential equations are the natural mathematical tool for quantifying change, and are the driving force throughout this book. The use of Euler’s method makes nonlinear examples tractable and accessible to a broad spectrum of early-stage undergraduates, thus providing a practical alternative to the procedural approach of a traditional Calculus curriculum. Tools are developed within numerous, relevant examples, with an emphasis on the construction, evaluation, and interpretation of mathematical models throughout. Encountering these concepts in context, students learn not only quantitative techniques, but how to bridge between biological and mathematical ways of thinking. Examples range broadly, exploring the dynamics of neurons and the immune system, through to population dynamics and the Google PageRank algorithm. Each scenario relies only on an interest in the natural world; no biological expertise is assumed of student or instructor. Building on a single prerequisite of Precalculus, the book suits a two-quarter sequence for first or second year undergraduates, and meets the mathematical requirements of medical school entry. The later material provides opportunities for more advanced students in both mathematics and life sciences to revisit theoretical knowledge in a rich, real-world framework. In all cases, the focus is clear: how does the math help us understand the science?

Modelling Nature

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Author :
Publisher : CABI
ISBN 13 : 1786393107
Total Pages : 281 pages
Book Rating : 4.7/5 (863 download)

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Book Synopsis Modelling Nature by : Edward Gillman

Download or read book Modelling Nature written by Edward Gillman and published by CABI. This book was released on 2019-05-30 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: This short textbook introduces students to the concept of describing natural systems using mathematical models. We highlight the variety of ways in which natural systems lend themselves to mathematical description and the importance of models in revealing fundamental processes. The process of science via the building, testing and use of models (theories) is described and forms the structure of the book. The book covers a broad range from the molecular to ecosystems and whole-Earth phenomena. Themes running through the chapters include scale (temporal and spatial), change (linear and nonlinear), emergent phenomena and uncertainty. Mathematical descriptions are kept to a minimum and we illustrate mechanisms and results in graphical form wherever possible. Essential mathematical details are described fully, with the use of boxes. The mathematics supports but does not lead the text.

Mathematical Modeling

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Author :
Publisher : Springer
ISBN 13 : 3319551612
Total Pages : 519 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Mathematical Modeling by : Christof Eck

Download or read book Mathematical Modeling written by Christof Eck and published by Springer. This book was released on 2017-04-11 with total page 519 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mathematical models are the decisive tool to explain and predict phenomena in the natural and engineering sciences. With this book readers will learn to derive mathematical models which help to understand real world phenomena. At the same time a wealth of important examples for the abstract concepts treated in the curriculum of mathematics degrees are given. An essential feature of this book is that mathematical structures are used as an ordering principle and not the fields of application. Methods from linear algebra, analysis and the theory of ordinary and partial differential equations are thoroughly introduced and applied in the modeling process. Examples of applications in the fields electrical networks, chemical reaction dynamics, population dynamics, fluid dynamics, elasticity theory and crystal growth are treated comprehensively.

Methods of Mathematical Modelling

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Publisher : Springer
ISBN 13 : 3319230425
Total Pages : 309 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Methods of Mathematical Modelling by : Thomas Witelski

Download or read book Methods of Mathematical Modelling written by Thomas Witelski and published by Springer. This book was released on 2015-09-18 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents mathematical modelling and the integrated process of formulating sets of equations to describe real-world problems. It describes methods for obtaining solutions of challenging differential equations stemming from problems in areas such as chemical reactions, population dynamics, mechanical systems, and fluid mechanics. Chapters 1 to 4 cover essential topics in ordinary differential equations, transport equations and the calculus of variations that are important for formulating models. Chapters 5 to 11 then develop more advanced techniques including similarity solutions, matched asymptotic expansions, multiple scale analysis, long-wave models, and fast/slow dynamical systems. Methods of Mathematical Modelling will be useful for advanced undergraduate or beginning graduate students in applied mathematics, engineering and other applied sciences.

Mathematical Systems Theory I

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Publisher : Springer Science & Business Media
ISBN 13 : 3540441255
Total Pages : 818 pages
Book Rating : 4.5/5 (44 download)

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Book Synopsis Mathematical Systems Theory I by : Diederich Hinrichsen

Download or read book Mathematical Systems Theory I written by Diederich Hinrichsen and published by Springer Science & Business Media. This book was released on 2011-08-03 with total page 818 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the mathematical foundations of systems theory in a self-contained, comprehensive, detailed and mathematically rigorous way. It is devoted to the analysis of dynamical systems and combines features of a detailed introductory textbook with that of a reference source. The book contains many examples and figures illustrating the text which help to bring out the intuitive ideas behind the mathematical constructions.

Cardiovascular Mathematics

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Publisher : Springer Science & Business Media
ISBN 13 : 8847011523
Total Pages : 528 pages
Book Rating : 4.8/5 (47 download)

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Book Synopsis Cardiovascular Mathematics by : Luca Formaggia

Download or read book Cardiovascular Mathematics written by Luca Formaggia and published by Springer Science & Business Media. This book was released on 2010-06-27 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mathematical models and numerical simulations can aid the understanding of physiological and pathological processes. This book offers a mathematically sound and up-to-date foundation to the training of researchers and serves as a useful reference for the development of mathematical models and numerical simulation codes.

Mathematics for Dynamic Modeling

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Author :
Publisher :
ISBN 13 :
Total Pages : 302 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Mathematics for Dynamic Modeling by : Edward J. Beltrami

Download or read book Mathematics for Dynamic Modeling written by Edward J. Beltrami and published by . This book was released on 1987 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new edition of Mathematics for Dynamic covers tools such as linearization, feedback concepts, the use of Liapunov functions, and optimal control. Each chapter includes exercises, many of which expand on the material in the text.

RFID in Logistics

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Publisher : CRC Press
ISBN 13 : 1420009362
Total Pages : 522 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis RFID in Logistics by : Erick C. Jones

Download or read book RFID in Logistics written by Erick C. Jones and published by CRC Press. This book was released on 2007-12-03 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radio Frequency Identification (RFID) tagging is now mandated by the department of defense and many of the world's largest retailers including Wal-Mart. In order to stay competitive, more than 200,000 manufacturers and suppliers must develop strategies for integrating RFID technologies into their supply chains. RFID in Logistics: A Practical Introd

A Biologist's Guide to Mathematical Modeling in Ecology and Evolution

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Publisher : Princeton University Press
ISBN 13 : 1400840910
Total Pages : 745 pages
Book Rating : 4.4/5 (8 download)

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Book Synopsis A Biologist's Guide to Mathematical Modeling in Ecology and Evolution by : Sarah P. Otto

Download or read book A Biologist's Guide to Mathematical Modeling in Ecology and Evolution written by Sarah P. Otto and published by Princeton University Press. This book was released on 2011-09-19 with total page 745 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thirty years ago, biologists could get by with a rudimentary grasp of mathematics and modeling. Not so today. In seeking to answer fundamental questions about how biological systems function and change over time, the modern biologist is as likely to rely on sophisticated mathematical and computer-based models as traditional fieldwork. In this book, Sarah Otto and Troy Day provide biology students with the tools necessary to both interpret models and to build their own. The book starts at an elementary level of mathematical modeling, assuming that the reader has had high school mathematics and first-year calculus. Otto and Day then gradually build in depth and complexity, from classic models in ecology and evolution to more intricate class-structured and probabilistic models. The authors provide primers with instructive exercises to introduce readers to the more advanced subjects of linear algebra and probability theory. Through examples, they describe how models have been used to understand such topics as the spread of HIV, chaos, the age structure of a country, speciation, and extinction. Ecologists and evolutionary biologists today need enough mathematical training to be able to assess the power and limits of biological models and to develop theories and models themselves. This innovative book will be an indispensable guide to the world of mathematical models for the next generation of biologists. A how-to guide for developing new mathematical models in biology Provides step-by-step recipes for constructing and analyzing models Interesting biological applications Explores classical models in ecology and evolution Questions at the end of every chapter Primers cover important mathematical topics Exercises with answers Appendixes summarize useful rules Labs and advanced material available

Principles of Mathematical Modeling

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Publisher : Elsevier
ISBN 13 : 0080470289
Total Pages : 323 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Principles of Mathematical Modeling by : Clive Dym

Download or read book Principles of Mathematical Modeling written by Clive Dym and published by Elsevier. This book was released on 2004-08-10 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: Science and engineering students depend heavily on concepts of mathematical modeling. In an age where almost everything is done on a computer, author Clive Dym believes that students need to understand and "own" the underlying mathematics that computers are doing on their behalf. His goal for Principles of Mathematical Modeling, Second Edition, is to engage the student reader in developing a foundational understanding of the subject that will serve them well into their careers. The first half of the book begins with a clearly defined set of modeling principles, and then introduces a set of foundational tools including dimensional analysis, scaling techniques, and approximation and validation techniques. The second half demonstrates the latest applications for these tools to a broad variety of subjects, including exponential growth and decay in fields ranging from biology to economics, traffic flow, free and forced vibration of mechanical and other systems, and optimization problems in biology, structures, and social decision making. Prospective students should have already completed courses in elementary algebra, trigonometry, and first-year calculus and have some familiarity with differential equations and basic physics. - Serves as an introductory text on the development and application of mathematical models - Focuses on techniques of particular interest to engineers, scientists, and others who model continuous systems - Offers more than 360 problems, providing ample opportunities for practice - Covers a wide range of interdisciplinary topics--from engineering to economics to the sciences - Uses straightforward language and explanations that make modeling easy to understand and apply New to this Edition: - A more systematic approach to mathematical modeling, outlining ten specific principles - Expanded and reorganized chapters that flow in an increasing level of complexity - Several new problems and updated applications - Expanded figure captions that provide more information - Improved accessibility and flexibility for teaching

Mathematical Models in Biology

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Publisher : SIAM
ISBN 13 : 9780898719147
Total Pages : 629 pages
Book Rating : 4.7/5 (191 download)

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Book Synopsis Mathematical Models in Biology by : Leah Edelstein-Keshet

Download or read book Mathematical Models in Biology written by Leah Edelstein-Keshet and published by SIAM. This book was released on 1988-01-01 with total page 629 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mathematical Models in Biology is an introductory book for readers interested in biological applications of mathematics and modeling in biology. A favorite in the mathematical biology community, it shows how relatively simple mathematics can be applied to a variety of models to draw interesting conclusions. Connections are made between diverse biological examples linked by common mathematical themes. A variety of discrete and continuous ordinary and partial differential equation models are explored. Although great advances have taken place in many of the topics covered, the simple lessons contained in this book are still important and informative. Audience: the book does not assume too much background knowledge--essentially some calculus and high-school algebra. It was originally written with third- and fourth-year undergraduate mathematical-biology majors in mind; however, it was picked up by beginning graduate students as well as researchers in math (and some in biology) who wanted to learn about this field.

Introduction to Mathematical Modeling and Computer Simulations

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Publisher : CRC Press
ISBN 13 : 1351998757
Total Pages : 202 pages
Book Rating : 4.3/5 (519 download)

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Book Synopsis Introduction to Mathematical Modeling and Computer Simulations by : Vladimir Mityushev

Download or read book Introduction to Mathematical Modeling and Computer Simulations written by Vladimir Mityushev and published by CRC Press. This book was released on 2018-02-19 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction to Mathematical Modeling and Computer Simulations is written as a textbook for readers who want to understand the main principles of Modeling and Simulations in settings that are important for the applications, without using the profound mathematical tools required by most advanced texts. It can be particularly useful for applied mathematicians and engineers who are just beginning their careers. The goal of this book is to outline Mathematical Modeling using simple mathematical descriptions, making it accessible for first- and second-year students.

Mathematical Modeling of Collective Behavior in Socio-Economic and Life Sciences

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 0817649468
Total Pages : 437 pages
Book Rating : 4.8/5 (176 download)

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Book Synopsis Mathematical Modeling of Collective Behavior in Socio-Economic and Life Sciences by : Giovanni Naldi

Download or read book Mathematical Modeling of Collective Behavior in Socio-Economic and Life Sciences written by Giovanni Naldi and published by Springer Science & Business Media. This book was released on 2010-08-12 with total page 437 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using examples from finance and modern warfare to the flocking of birds and the swarming of bacteria, the collected research in this volume demonstrates the common methodological approaches and tools for modeling and simulating collective behavior. The topics presented point toward new and challenging frontiers of applied mathematics, making the volume a useful reference text for applied mathematicians, physicists, biologists, and economists involved in the modeling of socio-economic systems.

Mathematical Modeling

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Author :
Publisher : CRC Press
ISBN 13 : 1351022938
Total Pages : 419 pages
Book Rating : 4.3/5 (51 download)

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Book Synopsis Mathematical Modeling by : Sandip Banerjee

Download or read book Mathematical Modeling written by Sandip Banerjee and published by CRC Press. This book was released on 2021-11-11 with total page 419 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mathematical Modeling: Models, Analysis and Applications, Second Edition introduces models of both discrete and continuous systems. This book is aimed at newcomers who desires to learn mathematical modeling, especially students taking a first course in the subject. Beginning with the step-by-step guidance of model formulation, this book equips the reader about modeling with difference equations (discrete models), ODE’s, PDE’s, delay and stochastic differential equations (continuous models). This book provides interdisciplinary and integrative overview of mathematical modeling, making it a complete textbook for a wide audience. A unique feature of the book is the breadth of coverage of different examples on mathematical modelling, which include population models, economic models, arms race models, combat models, learning model, alcohol dynamics model, carbon dating, drug distribution models, mechanical oscillation models, epidemic models, tumor models, traffic flow models, crime flow models, spatial models, football team performance model, breathing model, two neuron system model, zombie model and model on love affairs. Common themes such as equilibrium points, stability, phase plane analysis, bifurcations, limit cycles, period doubling and chaos run through several chapters and their interpretations in the context of the model have been highlighted. In chapter 3, a section on estimation of system parameters with real life data for model validation has also been discussed. Features Covers discrete, continuous, spatial, delayed and stochastic models. Over 250 illustrations, 300 examples and exercises with complete solutions. Incorporates MATHEMATICA® and MATLAB®, each chapter contains Mathematica and Matlab codes used to display numerical results (available at CRC website). Separate sections for Projects. Several exercise problems can also be used for projects. Presents real life examples of discrete and continuous scenarios. The book is ideal for an introductory course for undergraduate and graduate students, engineers, applied mathematicians and researchers working in various areas of natural and applied sciences.

Mathematical Models in Biology

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Author :
Publisher : Springer
ISBN 13 : 3319234978
Total Pages : 207 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Mathematical Models in Biology by : Valeria Zazzu

Download or read book Mathematical Models in Biology written by Valeria Zazzu and published by Springer. This book was released on 2015-11-26 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents an exciting collection of contributions based on the workshop “Bringing Maths to Life” held October 27-29, 2014 in Naples, Italy. The state-of-the art research in biology and the statistical and analytical challenges facing huge masses of data collection are treated in this Work. Specific topics explored in depth surround the sessions and special invited sessions of the workshop and include genetic variability via differential expression, molecular dynamics and modeling, complex biological systems viewed from quantitative models, and microscopy images processing, to name several. In depth discussions of the mathematical analysis required to extract insights from complex bodies of biological datasets, to aid development in the field novel algorithms, methods and software tools for genetic variability, molecular dynamics, and complex biological systems are presented in this book. Researchers and graduate students in biology, life science, and mathematics/statistics will find the content useful as it addresses existing challenges in identifying the gaps between mathematical modeling and biological research. The shared solutions will aid and promote further collaboration between life sciences and mathematics.