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Author : Dale Halsey Lea
Publisher :
ISBN 13 : 9781938835735
Total Pages : 235 pages
Book Rating : 4.8/5 (357 download)
Download or read book Mastering Pharmacogenomics written by Dale Halsey Lea and published by . This book was released on 2014 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Mary Lou Sole
Publisher : Elsevier Health Sciences
ISBN 13 : 0323375537
Total Pages : 691 pages
Book Rating : 4.3/5 (233 download)
Download or read book Introduction to Critical Care Nursing - E-Book written by Mary Lou Sole and published by Elsevier Health Sciences. This book was released on 2016-08-08 with total page 691 pages. Available in PDF, EPUB and Kindle. Book excerpt: NEW! UPDATED content is included throughout, especially in topics such as nutrition, feeding tube connectors, the new PAD guidelines for pain management, Rapid Response Teams, sepsis guidelines, and valvular disorders and TAVR. NEW! Critical Reasoning Activities are interspersed throughout the text, to better promote development of clinical nursing judgment. NEW! Universal Collaborative Care Plan for the Critically Ill Patient addresses important aspects of collaborative/interprofessional care that apply to virtually all critically ill patients. NEW! Increased coverage of infection control addresses the QSEN safety competency and helps provide patient protection against the growing threat of drug-resistant infections. NEW! Coverage of cardiac assistive devices includes ECMO and other small, portable, bedside cardiac assistive devices. NEW! Refocused hemodynamic monitoring content emphasizes the noninvasive methods of hemodynamic monitoring that are becoming more prominent. NEW! Increased coverage of palliative care supports the book's strong focus on end-of-life care. Revised Organ Donation chapter is refocused to help nurses provide holistic care to families facing difficult end-of-life choices regarding organ donation, rather than on the details of transplantation procedures. NEW Patient Problems focus shifts the book’s emphasis from nursing diagnoses to the interprofessional care of patient problems.
Author : Federico Innocenti
Publisher : Springer Science & Business Media
ISBN 13 : 1592599575
Total Pages : 215 pages
Book Rating : 4.5/5 (925 download)
Download or read book Pharmacogenomics written by Federico Innocenti and published by Springer Science & Business Media. This book was released on 2008-02-03 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: Expert researchers and physician/clinicians describe in detail the newest and most commonly used technologies today in this rapidly advancing field. The authors provide readily reproducible methods for assessing the functional consequences of a certain polymorphism, evaluate the variety of genotyping platforms currently available, and discuss the management of pharmacogenomic information. Highlights include techniques for making a snapshot of the allele-specific variation in human gene expression, genome wide analysis of allele-specific expression using oligo microarrays, in vivo assays with HaploChIP, SNP genotyping in DNA pools, and PharmGKB, the pharmacogenetics and pharmacogenomics knowledge base. The methodologies for genotyping include denaturing high-performance liquid chromarography, pyrosequencing, kinetic-fluorescence detection, mass spectrometry, and TaqMan assay for insertion/deletions.
Author : Joseph S. Bertino
Publisher : McGraw Hill Professional
ISBN 13 : 0071813713
Total Pages : 289 pages
Book Rating : 4.0/5 (718 download)
Download or read book Pharmacogenomics An Introduction and Clinical Perspective written by Joseph S. Bertino and published by McGraw Hill Professional. This book was released on 2012-10-12 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: A COMPLETE INTRODUCTORY TEXT TO THE FIELD OF PHARMACOGENOMICS The only pharmacogenomics resource to feature a global author team comprised of PharmDs, MDs, PhDs and social scientists, Pharmacogenomics offers an essential, highly accessible survey of this dynamic discipline. You will find thorough coverage of all need-to-know topics, from individual molecules to systemic diseases, plus an examination of the latest technologies that are constantly reshaping the field. Pharmacogenomics is cohesively organized into two sections, the first of which reviews basic aspects of pharmacogenomics, including ethics, regulatory, science, and drug metabolism, along with a "mini" course in molecular genetics and testing. The second section highlights the practical application of pharmacogenomics in cardiovascular medicine, immunology, neurology, and other specialties. FEATURES Important overview of general pharmacogenomics and pharmacogenetics concepts, including genetic variation in signal transduction and targets, plus a review of the genetic concepts of pharmacogenomics Discussion of regulatory considerations in pharmacogenomics Focus on the role of health care professionals along with a review of related privacy issues, as well as broader ethical, legal, and social considerations In-depth chapters on drug metabolism and transporters Practical, step-by-step guidance on public access to pharmacogenomic testing and patient counseling Up-to-date coverage of non-genetic influences on pharmacogenomics Emphasis on gene-drug interactions Numerous tables and figures Chapter-ending references Concise learning objectives at the beginning of each chapter Case studies to familiarize you with the clinical relevance of pharmacogenomics in each specialty
Author : Russ B. Altman
Publisher : Cambridge University Press
ISBN 13 : 052188537X
Total Pages : 283 pages
Book Rating : 4.5/5 (218 download)
Download or read book Principles of Pharmacogenetics and Pharmacogenomics written by Russ B. Altman and published by Cambridge University Press. This book was released on 2012-01-23 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook presents the latest information on pharmacogenetics and pharmacogenomics for students, professionals and researchers.
Author : Martin M. Zdanowicz
Publisher : ASHP
ISBN 13 : 1585282340
Total Pages : 425 pages
Book Rating : 4.5/5 (852 download)
Download or read book Concepts in Pharmacogenomics written by Martin M. Zdanowicz and published by ASHP. This book was released on 2010 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: The new science of pharmacogenomics aims to understand how an individual's genetic composition affects his/her response to a specific drug or class of drugs. By studying such characteristics as drug metabolizing enzymes, drug transporter activity, and receptor sensitivity, a pharmacist is better able to prescribe the right drug the first time.If you are pharmacist, resident, or student curious about this new field, start withConcepts in Pharmacogenomics. In this practical guide, you will find an overview of the science behind pharmacogenomics, followed by detailed chapters related to its clinical application and implementation.Features include: case studies in each chapter clinical pearls illustrations of key concepts figures, diagrams, and flow charts for visual learners key points summarized.
Author : Xiaodong Feng
Publisher : CRC Press
ISBN 13 : 1466582685
Total Pages : 308 pages
Book Rating : 4.4/5 (665 download)
Download or read book Applying Pharmacogenomics in Therapeutics written by Xiaodong Feng and published by CRC Press. This book was released on 2016-01-06 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in high-throughput gene sequencing and other omics biotechnologies have served as a springboard for the field of pharmacogenomics. Pharmacogenomics is now generally accepted as the major determinant of variable drug safety, efficacy, and cost-effectiveness. Therefore, widespread use of pharmacogenomics for patient care has become a critical requirement. There is an unprecedented urgency for aspiring and practicing clinicians to become trained on how to interpret data from pharmacogenomic testing in preparation for the future of healthcare—i.e., personalized medicine. Applying Pharmacogenomics in Therapeutics provides timely coverage of the principles, practice, and potential of pharmacogenomics and personalized medicine. Comprised of chapters contributed by well-established pharmacologists and scientists from US and Chinese academia and industry, this authoritative text: Demonstrates how to apply the principles of pharmacogenomics and its biotechnologies in patient care Depicts the use of genetic biomarkers in drug discovery and development, laboratory medicine, and clinical services Describes the practice of pharmacogenomics in the treatment of cancers, cardiovascular diseases, neurologic and psychiatric disorders, and pulmonary diseases Discusses the merging of pharmacogenomics and alternative medicine, as well as the integration of pharmacogenomics into pharmacoeconomics Each chapter begins with the key concepts, followed by in-depth explorations of case reports or critical evaluations of genetic variants/biomarkers, and concludes with questions for self-examination.
Author : Marilyn J. Hockenberry
Publisher : Elsevier Health Sciences
ISBN 13 : 0323485375
Total Pages : pages
Book Rating : 4.3/5 (234 download)
Download or read book Wong's Nursing Care of Infants and Children - E-Book written by Marilyn J. Hockenberry and published by Elsevier Health Sciences. This book was released on 2018-10-01 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Wong's Nursing Care of Infants and Children - E-Book
Author : Archith Boloor
Publisher : Jaypee Brothers Medical Publishers
ISBN 13 : 9390020743
Total Pages : 685 pages
Book Rating : 4.3/5 (9 download)
Download or read book Mastering Medicine written by Archith Boloor and published by Jaypee Brothers Medical Publishers. This book was released on 2020-10-31 with total page 685 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook is an essential revision aid for trainees preparing for Membership of the Royal College of Physicians (MRCP) examinations. Divided into 30 sections, the book begins with discussion on common symptoms and presentations, then emergency presentations. The following sections provide in depth coverage of the diagnosis and management of diseases and disorders in different body systems. The text concludes with chapters on geriatric medicine, genetics, epidemiology, clinical pharmacology, and ECG Interpretation. Treatment protocols are current and inline with the latest international guidelines. Each chapter is highly illustrated with images and figures, as well as teaching notes and easy-to-memorise lists to assist revision. Topics frequently encountered in examinations and key points are also highlighted. Key points Practical revision aid for trainees preparing for MRCP examinations Treatment protocols inline with current international guidelines Chapters highly illustrated with images and figures, and teaching notes to assist revision Highlights topics frequently encountered in examinations
Author : Whende M. Carroll, MSN, RN-BC
Publisher : Springer Publishing Company
ISBN 13 : 0826146511
Total Pages : 239 pages
Book Rating : 4.8/5 (261 download)
Download or read book Emerging Technologies for Nurses written by Whende M. Carroll, MSN, RN-BC and published by Springer Publishing Company. This book was released on 2020-02-01 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn and innovate with the latest technologies in nursing and healthcare! The first text of its kind in nursing, this book provides up-to-date information on innovative, smart technologies that nurses can use in clinical and nonclinical settings to keep up with the changing face of healthcare. This compelling guide will provide you with information about exciting areas of technology that have great potential to improve patient care. Subjects include big data, artificial intelligence, virtual and augmented realities, connected technologies, and precision health. There is also discusson of the shift of healthcare delivery into the community, with an outlook on improving outcomes and enhancing practice. Each chapter focuses on developing competency in current and future real-world applications of emerging technologies. Early chapters describe how to utilize new tools, processes, models, and products to serve the quadruple aim of better managing populations, decreasing costs, and enhancing both the patient’s and the clinician’s experience. The culture of innovation coincides with the ever-changing politics of healthcare in later chapters, which then evolves into the entrepreneurial opportunities for nurses. This text is an essential introduction for all practicing nurses, nurse leaders, and nurses teaching health information technology or informatics courses. Key Features: Written by nurses for nurses The latest information on emerging health information technology and associated nursing implications Compelling cases show the dramatic effect of innovations on value-based care Learn how applying novel technologies can improve patient care Qualified instructors have access to supplementary materials, including PowerPoint slides and an Instructor’s Manual
Author : David Mrazek
Publisher : Oxford University Press
ISBN 13 : 0195367294
Total Pages : 276 pages
Book Rating : 4.1/5 (953 download)
Download or read book Psychiatric Pharmacogenomics written by David Mrazek and published by Oxford University Press. This book was released on 2010-06-10 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Psychiatric Pharmacogenomics is a book written to help clinicians to use pharmacogenomic testing to improve the pharmacotherapy that they provide for their patients. It is designed to teach clinicians how to order pharmacogenomic tests and interpret the results. Clinical examples are used to underscore the specific indications for pharmacogenomic testing and to clarify the clinical usefulness of identifying atypical genotypes that result in problematic responses to medication. The first section of the book begins with a basic review of molecular genetics. Additionally, the book also includes an extensive glossary of technical terms associated with molecular genetics and pharmacogenomics. The clinical utility of pharmacogenomic testing is demonstrated throughout the book by describing the implications of genetic variations for the care of individual patients. The second section of the book is organized into fourteen chapters that each focus on the clinical implications of testing for specific genes for which variants have been associated with either therapeutic response or side effects of psychotropic medications. Each of these chapters is structured in the same manner and involves a description of the gene and its significant variants. Each chapter also includes one or more clinical vignettes. The third section of the book discusses the clinical usefulness of pharmacogenomic testing, ethical issues associated with pharmacogenomic testing, and provides predictions for the future development of more sophisticated pharmacogenomic testing.
Author : Dominic Front
Publisher : Richards Education
ISBN 13 :
Total Pages : 255 pages
Book Rating : 4./5 ( download)
Download or read book Mastering Biotechnology: Unveiling the Secrets of Genetic Engineering written by Dominic Front and published by Richards Education. This book was released on with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: Unlock the boundless potential of biotechnology with "Mastering Biotechnology: Unveiling the Secrets of Genetic Engineering." This comprehensive guide navigates readers through the intricate realms of genetic manipulation, molecular biology, and bioprocessing, offering a treasure trove of knowledge essential for aspiring biotechnologists and seasoned professionals alike. From unraveling the mysteries of DNA to harnessing the power of synthetic biology, each chapter delves into key concepts and cutting-edge techniques, providing a roadmap to mastering the intricate tools of the trade. Explore the frontiers of agricultural innovation, delve into the realms of medical breakthroughs, and discover how biotechnology is reshaping our world, from the laboratory bench to the global marketplace. With a keen eye on ethical considerations and societal impacts, "Mastering Biotechnology" is more than a guidebook—it's a beacon of insight into the ethical, legal, and social dimensions of biotechnological advancement. Whether you're a student, researcher, or industry professional, embark on a journey of discovery and empowerment with this indispensable companion to the fascinating world of biotechnology.
Author : Yui-Wing Francis Lam
Publisher : Academic Press
ISBN 13 : 0123983037
Total Pages : 515 pages
Book Rating : 4.1/5 (239 download)
Download or read book Pharmacogenomics written by Yui-Wing Francis Lam and published by Academic Press. This book was released on 2013-02-12 with total page 515 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmacogenomics: Challenges and Opportunities in Therapeutic Implementation includes discussions and viewpoints from the academic, regulatory, pharmaceutical, clinical, socio-ethical and economic perspectives. Each chapter presents an overview of the potential or opportunity within the areas discussed and also outlines foreseeable challenges and limitations in moving pharmacogenomics into drug development and direct therapeutic applications. This edited book contains review questions for a more in-depth analysis of the implications of pharmacogenomics and discussion points to generate ideas on best to move the field forward. Clinical pearls and case studies are used to illustrate real-life experiences and both successful and unsuccessful applications. Tables, figures, and annotations are included throughout the book to facilitate understanding and further reference. Multi-contributed book and chapters are written by contributors who are experts in their field Provides perspectives from those involved in all aspects of pharmacogenomics—including academic, regulatory, economic, industry and medical—to illustrate how all of the pieces fit together and where the challenges may be Includes case studies of both successful and unsuccessful applications so readers can consider the potential and challenges in moving the science into drug development and direct therapeutic applications Chapters contain discussion questions and clinical pearls and enable readers to reflect on how to move pharmacogenomics forward and apply these observations and useful tips to their own work and research
Author : Deborah Dang
Publisher : Sigma Theta Tau
ISBN 13 : 1938835301
Total Pages : 392 pages
Book Rating : 4.9/5 (388 download)
Download or read book Johns Hopkins Nursing Professional Practice Model: Strategies to Advance Nursing Excellence written by Deborah Dang and published by Sigma Theta Tau. This book was released on 2017-03-27 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Do you have a work culture that fosters collaboration, stimulates innovation, and empowers nurses to achieve success in exceptional ways? In Johns Hopkins Nursing Professional Practice Model: Strategies to Advance Nursing Excellence, authors Deborah Dang, Judith Rohde, and Jeannette Suflita present a model proven to inspire professional nurses to deliver exceptional care delivery and outcomes. Whether you’re a bedside nurse or an executive, you’ll learn how to adapt the Johns Hopkins Nursing Professional Practice Model to your work setting. Packed with exemplars, self-assessment guides, planning tools, and lessons learned, this manual guides you in creating and sustaining an environment where professional nursing practices flourish. Learn practical strategies to: Empower front-line nurses and encourage interprofessional collaboration Build and implement programs that promote adaptation, ownership, and accountability Establish practice and leadership standards Structure organizations to foster leadership and advance nursing excellence With a focus on achievement, caring, empowerment, and influence, Johns Hopkins Nursing Professional Practice Model can help reshape the future of nursing.
Author : Erika Cecchin
Publisher : MDPI
ISBN 13 : 3039367307
Total Pages : 208 pages
Book Rating : 4.0/5 (393 download)
Download or read book Pharmacogenomics and Personalized Medicine written by Erika Cecchin and published by MDPI. This book was released on 2021-01-20 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmacogenomics is one of the emerging approaches to precision medicine, tailoring drug selection and dosing to the patient’s genetic features. In recent years, several pharmacogenetic guidelines have been published by international scientific consortia, but the uptake in clinical practice is still poor. Many coordinated international efforts are ongoing in order to overcome the existing barriers to pharmacogenomic implementation. On the other hand, existing validated pharmacogenomic markers can explain only a minor part of the observed clinical variability in the therapeutic outcome. New investigational approaches are warranted, including a study of the pharmacogenomic role of the immune system genetics and of previously neglected rare genetic variants, reported to account for a large part of inter-individual variability in drug metabolism. In this book, we have collected a series of articles covering many aspects of pharmacogenomics. These include clinical implementation of pharmacogenomics in clinical practice, development of tools or infrastructures to support this process, research of new pharmacogenomics markers to increase drug efficacy and safety, and the impact of rare genetic variants in pharmacogenomics.
Author : Sandosh Padmanabhan
Publisher : Academic Press
ISBN 13 : 0123868831
Total Pages : 1119 pages
Book Rating : 4.1/5 (238 download)
Download or read book Handbook of Pharmacogenomics and Stratified Medicine written by Sandosh Padmanabhan and published by Academic Press. This book was released on 2014-04-28 with total page 1119 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Pharmacogenomics and Stratified Medicine is a comprehensive resource to understand this rapidly advancing field aiming to deliver the right drug at the right dose to the right patient at the right time. It is designed to provide a detailed, but accessible review of the entire field from basic principles to applications in various diseases. The chapters are written by international experts to allow readers from a wide variety of backgrounds, clinical and non-clinical (basic geneticists, pharmacologists, clinicians, trialists, industry personnel, ethicists) to understand the principles underpinning the progress in this area, the successes, failures and the challenges ahead. To be accessible to the widest range of readers, the clinical application section introduces the disease process, existing therapies, followed by pharmacogenomics and stratified medicine details. Medicine is the cornerstone of modern therapeutics prescribed on the basis that its benefit should outweigh its risk. It is well known that people respond differently to medications and in many cases the risk-benefit ratio for a particular drug may be a gray area. The last decade has seen a revolution in genomics both in terms of technological innovation and discovering genetic markers associated with disease. In parallel there has been steady progress in trying to make medicines safer and tailored to the individual. This has occurred across the whole spectrum of medicine, some more than others. In addition there is burgeoning interest from the pharmaceutical industry to leverage pharmacogenomics for more effective and efficient clinical drug development. Provides clinical and non-clinical researchers with practical information normally beyond their usual areas of research or expertise Includes an basic principles section explaining concepts of basic genetics, genetic epidemiology, bioinformatics, pharmacokinetics and pharmacodynamics Covers newer technologies– next generation sequencing, proteomics, metabolomics Provides information on animal models, lymphoblastoid cell lines, stem cells Provides detailed chapters on a wide range of disease conditions, implementation and regulatory issues Includes chapters on the global implications of pharmacogenomics
Author : Jerika T. Lam
Publisher : McGraw Hill Professional
ISBN 13 : 1260457117
Total Pages : 186 pages
Book Rating : 4.2/5 (64 download)
Download or read book Pharmacogenomics: A Primer for Clinicians written by Jerika T. Lam and published by McGraw Hill Professional. This book was released on 2020-12-22 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: An invaluable resource to the rapidly emerging field of pharmacogenomics—complete with case studies, clinical pearls, and treatment recommendations The aim of pharmacogenomics is to improve personalized medicine by taking into account how genes affect an individual’s tolerability and response to drugs. Approaching pharmacogenomics from the current clinical, scientific, and implementation perspectives, this guide serves as an invaluable evidence-based resource to the subject. Reflecting the shift from genetics to genomics in the pharmaceutical sphere, the book covers pharmacogenomics fundamentals; genotyping tests and evidence; clinical implementation; ethical, legal, and social issues; and more. You’ll also find illuminating case scenarios, clinical pearls, and evidence-based recommendations for treatments and alternatives based on CPIC, PharmGKB, and FDA guidelines.
