Mast Cells

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Mast Cells United: A Holistic Approach to Mast Cell Activation Syndrome

Author : Amber Walker
Publisher : Amber Walker
ISBN 13 : 1733711716
Total Pages : 542 pages
Book Rating : 4.7/5 (337 download)

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Book Synopsis Mast Cells United: A Holistic Approach to Mast Cell Activation Syndrome by : Amber Walker

Download or read book Mast Cells United: A Holistic Approach to Mast Cell Activation Syndrome written by Amber Walker and published by Amber Walker. This book was released on 2019-03-16 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt: At 542 pages and referencing over 1200 academic articles, this book is the longest and most thorough resource on mast cell activation syndrome (MCAS) to date. Allergies and anaphylaxis are on the rise, alongside gastrointestinal problems, skin issues, fatigue, orthopedic pain, neurological symptoms, and just about everything in between. Patients are coming out of the woodwork with chronic, debilitating, often invisible illness. Recent research estimates that 14%-17% of the population may have mast cell activation disease. Much of the medical community has never heard of the condition, and existing mainstream treatment tends to focus predominantly on pharmacological management. However, once a patient has reached a stable baseline, there are a number of other individualized approaches that can guide patients to successfully address the underlying root issues. This book includes: 1) an in-depth overview of mast cell activation disease, with a focus on mast cell activation syndrome (MCAS); 2) a patient story describing life with MCAS; 3) a detailed literature review and current hypotheses for disease origins; 4) a practical guide of clinical considerations for diagnosis; 5) a chapter devoted to comorbid conditions, including Ehlers-Danlos syndrome, POTS, Lyme disease and much more; 6) several chapters devoted to mainstream and natural treatment options, dietary considerations, and strategies for holistic healing; 7) content from dozens of interviews with prominent MCAS experts, including specialists in allergy/immunology, hematology, functional medicine, naturopathy, psychology, nutrition, gastroenterology, physical therapy, clinical research, and more! Whether a patient, medical practitioner, or family member/friend, this book empowers readers and provides patients with concrete steps to move forward in the diagnosis and comprehensive treatment of mast cell activation syndrome.

The Mast Cell

Author : Domenico Ribatti
Publisher :
ISBN 13 : 9783030241919
Total Pages : 112 pages
Book Rating : 4.2/5 (419 download)

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Book Synopsis The Mast Cell by : Domenico Ribatti

Download or read book The Mast Cell written by Domenico Ribatti and published by . This book was released on 2019 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the most important aspects of Mast Cell Biology. It enables the reader to immerse in the new aspects of Mast Cells biology, which are no longer seen as an immunological effector cell, but a multi-functional efector cell. One which have roles that expands beyond the immunological realm and shows deep implications in the pathophysiology of several human disorders as well as transforming into a very important and promising target for therapy development in cancer, neurodegerative disorders, angiogenesis, inflammation and allergy. Across twelve chapter on Mast Cells Research, starting from the discovery and characterization of Mast Cells until the lastest findings and translational perspectives, the reader will get a complete view and a profound insight on the fundamental and applied aspects of Mast Cells Biology. The chapters are written in a clear and concise way in order to help navigating through complex biological scenarios. The author, Domenico Ribatti, Full professor of the University of Bari, is an expert in the field of Mast Cells with more than 800 publications.

Mast Cell Biology

Author : Alasdair M. Gilfillan
Publisher : Springer Science & Business Media
ISBN 13 : 1441995331
Total Pages : 312 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Mast Cell Biology by : Alasdair M. Gilfillan

Download or read book Mast Cell Biology written by Alasdair M. Gilfillan and published by Springer Science & Business Media. This book was released on 2011-06-28 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: The editors of Mast Cell Biology, Drs. Gilfillan and Metcalfe, have enlisted an outstanding group of investigators to discuss the emerging concepts in mast cell biology with respect to development of these cells, their homeostasis, their activation, as well as their roles in maintaining health on the one hand and on the other, their participation in disease.

Mast Cells

Author : Michael R. Hughes
Publisher : Humana
ISBN 13 : 9781493951703
Total Pages : 0 pages
Book Rating : 4.9/5 (517 download)

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Book Synopsis Mast Cells by : Michael R. Hughes

Download or read book Mast Cells written by Michael R. Hughes and published by Humana. This book was released on 2016-09-22 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mast Cells: Methods and Protocols, Second Edition expands upon the previous edition with current, detailed reviews that cover topics of interest to mast cell neophytes and cognoscenti alike. With new chapters on methods for the enumeration of tissue mast cells and isolation of mature mast cells and mast cell progenitors from mammalian tissues, Danio rerio (zebrafish) model in the study of mast cell development and function, the functions of mast cells in human health and disease and methods for the isolation, methods for the investigation of the molecular mechanisms of mast cell activation and their effector functions, assays for the detection and analysis of mast cell secretory and cell surface phenotype and, mast cell activation state, and experimental mouse models of disease that have been deemed useful for the assessment of mast cell functions in the regulation of innate and adaptive immune response in cancer, tissue fibrosis, auto-inflammation and allergic disease. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Mast Cells: Methods and Protocols, Second Edition provides a sampler of useful methods and techniques in the further study of mast cell biology.

Mast Cells and Basophils

Author : Gianni Marone
Publisher : Academic Press
ISBN 13 : 0080535852
Total Pages : 738 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Mast Cells and Basophils by : Gianni Marone

Download or read book Mast Cells and Basophils written by Gianni Marone and published by Academic Press. This book was released on 2000-05-25 with total page 738 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mast Cells and Basophils will be essential reading for immunologists, biochemists and medical researchers. Detailed chapters cover all aspects of mast cell and basophil research, from cell development, proteases, histamine, cysteinyl leukotrienes, physiology and pathology to the role of these cells in health and disease. Chapters also discuss the clinical implications of histamine receptor antagonists.

Mast Cells, Mediators and Disease

Author : Stephen T. Holgate
Publisher : Springer Science & Business Media
ISBN 13 : 9400912870
Total Pages : 293 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis Mast Cells, Mediators and Disease by : Stephen T. Holgate

Download or read book Mast Cells, Mediators and Disease written by Stephen T. Holgate and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1879 Paul Ehrlich first described the mast cell as a tissue fixed cell contain ing many granules which, when stained with basic dyes, such as toluidine blue, changed the colour spectrum of the dye in a process called meta chromasia. Since this early description, pathologists, physicians and pharmacologists have been fascinated by this cell on account of its central involvement in human allergic diseases. Approximately four decades after Ehrlich's first description of the mast cell, Prausnitz and Kiistner reported their pioneer experiment, demonstrating that the immediate skin wheal response to allergen could be passively transferred with serum. They named the antigen-specific serum factor reagin. A further four and one half decades had to pass before the connection between the mast cell and reagin could be made with the identification of reagin as an immunoglobulin E by Johansson and Ishizaka and its unique property to bind with high affinity to specific receptors on mast cells and basophils. Meanwhile in the 1920s Coca published a series of papers in which he described the clinical features of acute allergic responses and first used the term atopy. This, together with the fundamental pharmacological studies of Sir Henry Dale in identifying histamine as one mediator of the acute ana phylactic reaction, provided the second approach which eventually linked the mast cell to allergic tissue reactions. Indeed, it was Best, working in Dale's group who first showed that histamine was a chemical stored in mast cells.

Holland-Frei Cancer Medicine

Author : Robert C. Bast, Jr.
Publisher : John Wiley & Sons
ISBN 13 : 111900084X
Total Pages : 2004 pages
Book Rating : 4.1/5 (19 download)

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Book Synopsis Holland-Frei Cancer Medicine by : Robert C. Bast, Jr.

Download or read book Holland-Frei Cancer Medicine written by Robert C. Bast, Jr. and published by John Wiley & Sons. This book was released on 2017-03-10 with total page 2004 pages. Available in PDF, EPUB and Kindle. Book excerpt: Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Mast Cells

Author : David B. Murray
Publisher : Nova Science Publishers
ISBN 13 : 9781626181663
Total Pages : 0 pages
Book Rating : 4.1/5 (816 download)

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Book Synopsis Mast Cells by : David B. Murray

Download or read book Mast Cells written by David B. Murray and published by Nova Science Publishers. This book was released on 2013 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Resident mast cells are uniquely positioned in multiple organ systems at either the tissue and/or external environment or located near nerve endings and/or blood vessels. These locations allow the mast cell to serve as a sentinel and thus play a critical role in not only inflammatory situations to promote recruitment and infiltration of other immune cells, but also homeostatic maintenance. Although mast cells have several conserved characteristics, the authors provide evidence that the micro-environment influenced differences in the phenotype of tissue-specific mast cells, control the various responses to injury, inflammation and remodelling. This book brings together the work from experts across multiple tissue/organ systems and inflammatory causes (viral, bacterial, and auto-immune) to present the most up to date knowledge regarding the role of mast cells in these regulatory and disease events.

Mast Cells

Author : Guha Krishnaswamy
Publisher : Springer Science & Business Media
ISBN 13 : 1592599672
Total Pages : 434 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Mast Cells by : Guha Krishnaswamy

Download or read book Mast Cells written by Guha Krishnaswamy and published by Springer Science & Business Media. This book was released on 2008-02-04 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: A cutting-edge collection of readily reproducible techniques for the isolation, culture, and study of activation and signaling in human mast cells. These methods take advantage of the latest advances in molecular biology, technology, and information science. They include methods for the identification of mast cells, the development of mast cells in vitro, the study of mast cell signaling and gene expression, and the measurement of mast cell expression of inflammatory mediators. Additional chapters cover methods for studying mast cell interactions with other cell types (endothelial cells, fibroblasts, and B cells), the roles of mast cells in host defense, and mast cell apoptosis.

The Mast Cell in Health and Disease

Author : Kaliner
Publisher : CRC Press
ISBN 13 : 9780824787325
Total Pages : 928 pages
Book Rating : 4.7/5 (873 download)

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Book Synopsis The Mast Cell in Health and Disease by : Kaliner

Download or read book The Mast Cell in Health and Disease written by Kaliner and published by CRC Press. This book was released on 1992-10-29 with total page 928 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offers coverage of practical and theoretical implications of current research into mast cell biology, emphasizing the role of the mast cell in human diseases. The text covers all aspects of the mast cell from growth and differentiation to its function in such conditions as asthma and skin disease.

Innovative Medicine

Author : Kazuwa Nakao
Publisher : Springer
ISBN 13 : 4431556516
Total Pages : 330 pages
Book Rating : 4.4/5 (315 download)

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Book Synopsis Innovative Medicine by : Kazuwa Nakao

Download or read book Innovative Medicine written by Kazuwa Nakao and published by Springer. This book was released on 2015-10-13 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is devoted to innovative medicine, comprising the proceedings of the Uehara Memorial Foundation Symposium 2014. It remains extremely rare for the findings of basic research to be developed into clinical applications, and it takes a long time for the process to be achieved. The task of advancing the development of basic research into clinical reality lies with translational science, yet the field seems to struggle to find a way to move forward. To create innovative medical technology, many steps need to be taken: development and analysis of optimal animal models of human diseases, elucidation of genomic and epidemiological data, and establishment of “proof of concept”. There is also considerable demand for progress in drug research, new surgical procedures, and new clinical devices and equipment. While the original research target may be rare diseases, it is also important to apply those findings more broadly to common diseases. The book covers a wide range of topics and is organized into three complementary parts. The first part is basic research for innovative medicine, the second is translational research for innovative medicine, and the third is new technology for innovative medicine. This book helps to understand innovative medicine and to make progress in its realization.

The Mast Cell

Author : Domenico Ribatti
Publisher : Springer
ISBN 13 : 3030241904
Total Pages : 112 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis The Mast Cell by : Domenico Ribatti

Download or read book The Mast Cell written by Domenico Ribatti and published by Springer. This book was released on 2019-07-11 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mast cells (MC) are phylogenetically old cells which are distributed throughout the human organism. MC are found in almost all of the major organs and tissues of the body, particularly in association with connective tissue structures such as blood vessels, lymphatic vessels and nerves, and in proximity to surfaces that interface the external environment, such as those of the respiratory and gastrointestinal system and the skin. This selective accumulation at tissue sites where foreign material attempts to invade the host suggests that MC are among the first cells to initiate defensive mechanisms. MC have long been recognized as key cells of type I hypersensitivity reactions. Several lines of evidence, however, indicate that they not only express critical effector functions in classic IgE-associated allergic disorders, but also play important roles in host defense against parasites, bacteria and perhaps even viruses. Indeed, it is now clear that MC can contribute to host defense in the context of either acquired or innate immune responses through the release of a myriad of pro-inflammatory and immunoregulatory molecules and the expression of a wide spectrum of surface receptors for cytokines and chemokines. Moreover, there is growing evidence that MC exert distinct non-immunological functions, playing a relevant role in tissue homeostasis, remodeling and fibrosis as well as in the processes of tissue angiogenesis.

Human Mast Cells

Author : Ann M. Dvorak
Publisher : Springer Science & Business Media
ISBN 13 : 3642741452
Total Pages : 173 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Human Mast Cells by : Ann M. Dvorak

Download or read book Human Mast Cells written by Ann M. Dvorak and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book looks in detail at human mast cells. It includes a review of previous and current ultrastructural studies, whereby the latter are illustrated with numerous high-quality electron micrographs obtained from a large number of structural and functional experiments using highly purified isolated human lung mast cells. Specifically, the book provides criteria for the identification of human mast cells, discusses the unique role in mast cell function of granules and lipid bodies, describes the ultrastructural anatomy of two release reactions - i.e., anaphylactic degranulation and piecemeal degranulation - and defines the recovery, cyclical and maturational properties of human mast cells. All of these new morphological-biochemical and functional studies are correlated with the author's wide experience in the visual properties of human mast cells as seen in biopsy material obtained from a diagnostic ultrastructural pathology service.

Janeway's Immunobiology

Author : Kenneth Murphy
Publisher : Garland Science
ISBN 13 : 9780815344575
Total Pages : pages
Book Rating : 4.3/5 (445 download)

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Book Synopsis Janeway's Immunobiology by : Kenneth Murphy

Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Mast Cells and Basophils

Author : Derek J. Chadwick
Publisher : John Wiley & Sons
ISBN 13 : 0470030518
Total Pages : 274 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Mast Cells and Basophils by : Derek J. Chadwick

Download or read book Mast Cells and Basophils written by Derek J. Chadwick and published by John Wiley & Sons. This book was released on 2006-01-04 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book presents recent advances relating to the factors and mechanisms that regulate the growth, differentiation and function of mast cells and basophils; discussion of new technologies used to study these cells, and integration of the basic scientific findings in the context of therapeutic possibilities for the treatment of diseases such as allergic inflammation and autoimmune disease which are mediated, in part, by these granulocytes.

Mast Cells in Itch, Pain and Neuro-inflammation

Author : Rashid Giniatullin
Publisher : Frontiers Media SA
ISBN 13 : 2889633470
Total Pages : 194 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Mast Cells in Itch, Pain and Neuro-inflammation by : Rashid Giniatullin

Download or read book Mast Cells in Itch, Pain and Neuro-inflammation written by Rashid Giniatullin and published by Frontiers Media SA. This book was released on 2020-01-27 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Mast Cell Disorders, An Issue of Immunology and Allergy Clinics of North America, E-Book

Author : Cem Akin
Publisher : Elsevier Health Sciences
ISBN 13 : 0443181845
Total Pages : 234 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Mast Cell Disorders, An Issue of Immunology and Allergy Clinics of North America, E-Book by : Cem Akin

Download or read book Mast Cell Disorders, An Issue of Immunology and Allergy Clinics of North America, E-Book written by Cem Akin and published by Elsevier Health Sciences. This book was released on 2023-09-30 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue of Immunology & Allergy Clinics, guest editor Dr. Cem Akin brings his considerable expertise to the topic of Mast Cell Disorders. Top experts in the field provide readers with information on the identification, management, and treatment of mast cell disorders and mastocytosis. Contains 9 relevant, practice-oriented topics including drug and venom allergy in mastocytosis; quality of life in mastocytosis; effect of gender and special considerations for women in mastocytosis and anaphylaxis; management of mediator symptoms, allergy, and anaphylaxis in mastocytosis; and more. Provides in-depth clinical reviews on mast cell disorders, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.