MAO - The Mother of all Amine Oxidases

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Publisher : Springer Science & Business Media
ISBN 13 : 3709164990
Total Pages : 359 pages
Book Rating : 4.7/5 (91 download)

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Book Synopsis MAO - The Mother of all Amine Oxidases by : John P.M. Finberg

Download or read book MAO - The Mother of all Amine Oxidases written by John P.M. Finberg and published by Springer Science & Business Media. This book was released on 2013-12-01 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt: Monoamine oxidase (MAO) is linked to psychiatric and neurological disorders, because inhibitors of the enzyme are used clinically for treatment of affective disorders and Parkinson’s disease. One of the interesting new aspects of MAO is the occurrence in the human population of deletions of genes coding for one or the other enzyme subtype (A or B). This leads to the possibility of a genetic basis for psychiatric disorders based on MAO. Subjects with deletions of type A or B, and combined deletions, have been described. In the first group of 6 papers in this book, the occurrence and characterization of these phenotypes, as well as the structure of MAO genes, is explored. Advances in the biochemistry of MAO subtypes and their physiological function and localization in brain and periphery is included. Other sections of the book deal with the neuroprotective action of MAO inhibitors and their pharmacology, especially the pharmacology of new MAO-B inhibitors.

Cumulated Index Medicus

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Publisher :
ISBN 13 :
Total Pages : 1792 pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis Cumulated Index Medicus by :

Download or read book Cumulated Index Medicus written by and published by . This book was released on 1998 with total page 1792 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Oxidative Stress and Neuroprotection

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Publisher : Springer Science & Business Media
ISBN 13 : 3211333282
Total Pages : 262 pages
Book Rating : 4.2/5 (113 download)

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Book Synopsis Oxidative Stress and Neuroprotection by : S.H. Parvez

Download or read book Oxidative Stress and Neuroprotection written by S.H. Parvez and published by Springer Science & Business Media. This book was released on 2006-12-26 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with basic and clinical aspects of monoamine oxidase (MAO) subtypes A and B highlighting its importance in neurological and psychiatric diseases. Consequently the therapeutic actions of MAO-A and -B inhibitors in Parkinson’s disease (PK) and depression are the focus of several chapters. As MAO is the basis of the development of the "oxidative stress hypothesis" of PD, several chapters are devoted to iron and iron-induced oxidative stress in various experimental studies and clinical conditions. Based on these findings, new compounds have been developed which not only block MAO, but are in addition, either inhibitors of acetylcholine esterase or have iron chelating properties. The aspect of "preclinical" and "clinical" neuro protection as well as MAO neuroprotection are additional topics covered in this book. MAO, iron and neuroprotection are seen in the framework of general anti Parkinson’s therapy with chapters on levodopa, dopaminergic receptor agonists and clinical issues.

Diagnosis and Treatment of Parkinson’s Disease — State of the Art

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Publisher : Springer Science & Business Media
ISBN 13 : 3709163609
Total Pages : 222 pages
Book Rating : 4.7/5 (91 download)

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Book Synopsis Diagnosis and Treatment of Parkinson’s Disease — State of the Art by : Horst Przuntek

Download or read book Diagnosis and Treatment of Parkinson’s Disease — State of the Art written by Horst Przuntek and published by Springer Science & Business Media. This book was released on 2013-12-01 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: Expert clinicians and basic scientists with a special interest in Parkinson’s disease review the current state of science and clinical therapeutics of the disease. Therefore these articles represent an authorative review of the current state of knowledge regarding preclinical course and symptomatology, subtypes with their impact on the pathology, genetic alterations, novel mechanisms of neuronal cell death, diagnostic tools and old and novel therapeutic approaches with respect to neuroprotection and neuroregeneration in Parkinson’s disease. Particular emphasis has been placed on a novel antiparkinsonian drug called budipine with various modes of action also influencing altered non dopaminergic systems in Parkinson’s disease. It is evident, that many questions on the cause, course and treatment of Parkinson’s disease are still unanswered and therefore the ideal way to treat a parkinsonian patient remains to be defined.

Alzheimer’s Disease - From Basic Research to Clinical Applications

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Publisher : Springer Science & Business Media
ISBN 13 : 3709175089
Total Pages : 313 pages
Book Rating : 4.7/5 (91 download)

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Book Synopsis Alzheimer’s Disease - From Basic Research to Clinical Applications by : Hermann J. Gertz

Download or read book Alzheimer’s Disease - From Basic Research to Clinical Applications written by Hermann J. Gertz and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: As human longevity continues to be extended, so will the impact of age-associated dementia on individual lives and society. Alzheimer’s disease as the most common cause of dementia in the elderly remains a sentinal problem and its underlying pathology is still poorly understood. Available therapeutic strategies require considerable refinement and the development of new therapeutic strategies need input from basic research. Thus continued efforts are necessary both to understand basic mechanisms of the condition and to achieve more powerfull therapies. This volume brings together the reports of basic scientists and clinical investigators. The chapters provide a spectrum of information valuable for clinicians and scientists. This issue bridges the gap between laboratory work in basic science and the development of urgently needed therapeutic strategies. Areas presented are the molecular and cellular biology of the disease, pathogenetic mechanisms and potential therapeutic targets, genetics, risk factors, strategies of prevention and treatment as well as practical aspects of medical and social care for patients with Alzheimer’s disease.

The Molecular Biology of Down Syndrome

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Publisher : Springer Science & Business Media
ISBN 13 : 3709163803
Total Pages : 362 pages
Book Rating : 4.7/5 (91 download)

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Book Synopsis The Molecular Biology of Down Syndrome by : G. Lubec

Download or read book The Molecular Biology of Down Syndrome written by G. Lubec and published by Springer Science & Business Media. This book was released on 2013-12-01 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains updated reviews and original research work on Down Syndrome focussing on brandnew results in neurobiology, in particular results on gene hunting (subtractive hybridization, differential display) and neurochemistry. The book provides new data such as a subtractive library of Down Syndrome brain showing cDNAs that are overexpressed or downregulated and can be regarded as a source for further research on the preliminary transcriptional data given. A 2D-electrophoretic map of human brain proteins including Down Syndrome brain protein expression established by in-gel-digestion of spots with subsequent MALDI-identification provides the scientific basis for protein work to the neuroscientist. Altogether, the book provides a series of new candidate genes possibly involved in Down Syndrome neurobiology, tools for neuroscience studies on Down Syndrome brain thus serving as a manual and updated views and aspects on Down Syndrome pathobiology.

Amine Oxidases and Their Impact on Neurobiology

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Publisher : Springer Science & Business Media
ISBN 13 : 3709191130
Total Pages : 467 pages
Book Rating : 4.7/5 (91 download)

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Book Synopsis Amine Oxidases and Their Impact on Neurobiology by : Peter Riederer

Download or read book Amine Oxidases and Their Impact on Neurobiology written by Peter Riederer and published by Springer Science & Business Media. This book was released on 2013-03-13 with total page 467 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Amine Oxidase Workshop was the brain child of Brian Callingham and Keith Tipton. The present book is the proceedings of the fourth in the series and in the past we have dedicated our meeting to individuals who have made significant fundamental contributions to the biochemistry, physiology and pharmacology of this interesting group of enzymes. The present meeting is not an exception because we have gathered here in Wtirzburg to honour an individual whose outstanding work on the autonomic pharmacology has span ned more than 30 years and whose contribution has made a vast impact in our understanding of the kinetic relationship between amine metabolism (that uptake and enzymatic inactivation) and adrenergic neurotransmission. We speak of course of Professor Ullrich Trendelenburg, or Ulli as he likes to be known. Like the amine oxidases, he has a unique place in Pharmacology. Professor Trendelenburg was born on the eve of the new year of 1922 in the city of Rostock in northern Germany, where his father was Professor of Pharmacology at the Faculty of Medicine of Rostock. His father accepted the offer to take over the corresponding chair in Freiburg im Breisgrau (in Southern Germany). As the youngest of four children, Ulli grew up mainly in the garden of the department, in the animal quarters and in the workshop. Of the various coworkers of his father, one he liked especially was Otto Krayer, the young pharmacologist.

Subject Guide to Books in Print

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Publisher :
ISBN 13 :
Total Pages : 2460 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Subject Guide to Books in Print by :

Download or read book Subject Guide to Books in Print written by and published by . This book was released on 1991 with total page 2460 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Advances in Clinical Obstetrics and Gynecology

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Publisher :
ISBN 13 :
Total Pages : 330 pages
Book Rating : 4.:/5 (39 download)

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Book Synopsis Advances in Clinical Obstetrics and Gynecology by :

Download or read book Advances in Clinical Obstetrics and Gynecology written by and published by . This book was released on 1982 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Advances in Clinical Obstetrics and Gynecology

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Publisher :
ISBN 13 :
Total Pages : 328 pages
Book Rating : 4.3/5 (555 download)

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Book Synopsis Advances in Clinical Obstetrics and Gynecology by : Howard J. Osofsky

Download or read book Advances in Clinical Obstetrics and Gynecology written by Howard J. Osofsky and published by . This book was released on 1982 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt:

International Abstracts of Biological Sciences

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ISBN 13 :
Total Pages : 750 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis International Abstracts of Biological Sciences by :

Download or read book International Abstracts of Biological Sciences written by and published by . This book was released on 1962 with total page 750 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Index Medicus

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ISBN 13 :
Total Pages : 2292 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Index Medicus by :

Download or read book Index Medicus written by and published by . This book was released on 2004 with total page 2292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

Complete Drug Reference

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ISBN 13 : 9780890437698
Total Pages : 1776 pages
Book Rating : 4.4/5 (376 download)

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Book Synopsis Complete Drug Reference by :

Download or read book Complete Drug Reference written by and published by . This book was released on 1994 with total page 1776 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Enzyme Catalysis in Organic Synthesis

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ISBN 13 :
Total Pages : 616 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Enzyme Catalysis in Organic Synthesis by : Karlheinz Drauz

Download or read book Enzyme Catalysis in Organic Synthesis written by Karlheinz Drauz and published by . This book was released on 2002 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Usp Di Vol. II

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Publisher : United States Pharmacopeia
ISBN 13 : 9780913595848
Total Pages : 1822 pages
Book Rating : 4.5/5 (958 download)

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Book Synopsis Usp Di Vol. II by : United States Pharmacopeial Convention

Download or read book Usp Di Vol. II written by United States Pharmacopeial Convention and published by United States Pharmacopeia. This book was released on 1995 with total page 1822 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Amine Oxidase Inhibitors

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ISBN 13 :
Total Pages : 512 pages
Book Rating : 4.E/5 ( download)

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Download or read book Amine Oxidase Inhibitors written by and published by . This book was released on 1959 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt:

New Scientist

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ISBN 13 :
Total Pages : 930 pages
Book Rating : 4.2/5 (267 download)

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Book Synopsis New Scientist by :

Download or read book New Scientist written by and published by . This book was released on 1981 with total page 930 pages. Available in PDF, EPUB and Kindle. Book excerpt: