Treatment and Prevention of Malaria

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Publisher : Springer Science & Business Media
ISBN 13 : 3034604793
Total Pages : 318 pages
Book Rating : 4.0/5 (346 download)

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Book Synopsis Treatment and Prevention of Malaria by : Henry M. Staines

Download or read book Treatment and Prevention of Malaria written by Henry M. Staines and published by Springer Science & Business Media. This book was released on 2012-01-06 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: Malaria has defeated previous efforts at eradication and remains a massive global public health problem despite being readily preventable and treatable. It is a devastating disease that also extracts huge economic costs from the poorest countries in endemic regions. Starting with an overview of the disease and its current political, financial and technical context, this Milestones in Drug Therapy volume describes the history, chemistry, mechanisms of action and resistance, preclinical and clinical use, pharmacokinetics and safety and tolerability of the current range of antimalarial drugs. There is particular emphasis on artemisinins and related peroxides, as these drugs have now become the frontline treatment for malaria. Next generation antimalarials, molecular markers for detecting resistance, the importance of diagnostics and disease prevention are also covered in detail.

Malaria Frontline

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Publisher : Melbourne University
ISBN 13 : 9780522850338
Total Pages : 0 pages
Book Rating : 4.8/5 (53 download)

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Book Synopsis Malaria Frontline by : Tony Sweeney

Download or read book Malaria Frontline written by Tony Sweeney and published by Melbourne University. This book was released on 2003 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: During World War II malaria was one of the most powerful enemies of the Australian troops in the South West Pacific. In 1943 the Australian Army formed a special research team to tackle the problem. This book documents the Australian search for a cure, and the scientific breakthroughs.

Guidelines for the Treatment of Malaria. Third Edition

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Publisher : World Health Organization
ISBN 13 : 9241549122
Total Pages : 317 pages
Book Rating : 4.2/5 (415 download)

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Book Synopsis Guidelines for the Treatment of Malaria. Third Edition by : World Health Organization

Download or read book Guidelines for the Treatment of Malaria. Third Edition written by World Health Organization and published by World Health Organization. This book was released on 2015-08-13 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: Malaria remains an important cause of illness and death in children and adults in countries in which it is endemic. Malaria control requires an integrated approach including prevention (primarily vector control) and prompt treatment with effective antimalarial agents. Malaria case management consisting of prompt diagnosis and effective treatment remains a vital component of malaria control and elimination strategies. Since the publication of the first edition of the Guidelines for the treatment of malaria in 2006 and the second edition in 2010 all countries in which P. falciparum malaria is endemic have progressively updated their treatment policy from use of ineffective monotherapy to the currently recommended artemisinin-based combination therapies (ACT). This has contributed substantially to current reductions in global morbidity and mortality from malaria. Unfortunately resistance to artemisinins has arisen recently in P. falciparum in South-East Asia which threatens these gains. This third edition of the WHO Guidelines for the treatment of malaria contains updated recommendations based on a firmer evidence base for most antimalarial drugs and in addition include recommendation on the use of drugs to prevent malaria in groups at high risk. The Guidelines provide a framework for designing specific detailed national treatment protocols taking into account local patterns of resistance to antimalarial drugs and health service capacity. It provides recommendations on treatment of uncomplicated and severe malaria in all age groups all endemic areas in special populations and several complex situations. In addition on the use of antimalarial drugs as preventive therapy in healthy people living in malaria-endemic areas who are high risk in order to reduce morbidity and mortality from malaria. The Guidelines are designed primarily for policy-makers in ministries of health who formulate country-specific treatment guidelines. Other groups that may find them useful include health professionals and public health and policy specialists that are partners in health or malaria control and the pharmaceutical industry. The treatment recommendations in the main document are brief; for those who wish to study the evidence base in more detail a series of annexes is provided with references to the appropriate sections of the main document.

Battling Malaria

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Author :
Publisher : Twenty-First Century Books
ISBN 13 : 0822585804
Total Pages : 132 pages
Book Rating : 4.8/5 (225 download)

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Book Synopsis Battling Malaria by : Connie Goldsmith

Download or read book Battling Malaria written by Connie Goldsmith and published by Twenty-First Century Books. This book was released on 2010-08-01 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents an overview of the disease, discussing its history, symptoms, the prognosis of people who have contracted it, and how they are treated, along with current efforts to improve prevention measures and develop a vaccine.

Saving Lives, Buying Time

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Publisher : National Academies Press
ISBN 13 : 0309165938
Total Pages : 384 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Saving Lives, Buying Time by : Institute of Medicine

Download or read book Saving Lives, Buying Time written by Institute of Medicine and published by National Academies Press. This book was released on 2004-09-09 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: For more than 50 years, low-cost antimalarial drugs silently saved millions of lives and cured billions of debilitating infections. Today, however, these drugs no longer work against the deadliest form of malaria that exists throughout the world. Malaria deaths in sub-Saharan Africaâ€"currently just over one million per yearâ€"are rising because of increased resistance to the old, inexpensive drugs. Although effective new drugs called "artemisinins" are available, they are unaffordable for the majority of the affected population, even at a cost of one dollar per course. Saving Lives, Buying Time: Economics of Malaria Drugs in an Age of Resistance examines the history of malaria treatments, provides an overview of the current drug crisis, and offers recommendations on maximizing access to and effectiveness of antimalarial drugs. The book finds that most people in endemic countries will not have access to currently effective combination treatments, which should include an artemisinin, without financing from the global community. Without funding for effective treatment, malaria mortality could double over the next 10 to 20 years and transmission will intensify.

Guidelines for the Treatment of Malaria

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Author :
Publisher : World Health Organization
ISBN 13 : 9241547928
Total Pages : 208 pages
Book Rating : 4.2/5 (415 download)

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Book Synopsis Guidelines for the Treatment of Malaria by : World Health Organization

Download or read book Guidelines for the Treatment of Malaria written by World Health Organization and published by World Health Organization. This book was released on 2010 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The purpose of this document is to provide comprehensible, global, evidence-based guidelines to help formulate policies and protocols for the treatment of malaria. Information is presented on the treatment of uncomplicated malaria, including disease in special groups (young children, pregnant women, people who are HIV positive, travellers from non-malaria endemic regions) and in complex emergency situations and severe malaria."--Publisher's description.

Disease Control Priorities, Third Edition (Volume 6)

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Publisher : World Bank Publications
ISBN 13 : 1464805253
Total Pages : 1027 pages
Book Rating : 4.4/5 (648 download)

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Book Synopsis Disease Control Priorities, Third Edition (Volume 6) by : King K. Holmes

Download or read book Disease Control Priorities, Third Edition (Volume 6) written by King K. Holmes and published by World Bank Publications. This book was released on 2017-11-06 with total page 1027 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

Antimalarial Agents

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Publisher : Elsevier
ISBN 13 : 0081012101
Total Pages : 622 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Antimalarial Agents by : Graham L. Patrick

Download or read book Antimalarial Agents written by Graham L. Patrick and published by Elsevier. This book was released on 2020-06-16 with total page 622 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antimalarial Agents: Design and Mechanism of Action seeks to support medicinal chemists in their work toward antimalarial solutions, providing practical guidance on past and current developments and highlighting promising leads for the future. Malaria is a deadly disease which threatens half of the world's population. Advances over several decades have seen vast improvements in the eff ectiveness of both preventative measures and treatments, but the rapid adaptability of the disease means that the ongoing search for improved and novel antimalarial drugs is essential. Beginning with a historical overview of malaria and antimalarial research, this book goes on to describe the biological aspects of malaria, highlighting the lifecycle of the parasite responsible for malaria, the problem of resistance, genetic mapping of the parasite's genome, established drug targets, and potential drug targets for the future. This sets the scene for the following chapters which provide a detailed study of the medicinal chemistry of antimalarial agents, with a focus on the design of antimalarial drugs. Drawing on the knowledge of its experienced authors, and coupling historic research with current fi ndings to provide a full picture of both past and current milestones, Antimalarial Agents: Design and Mechanism of Action is a comprehensive yet accessible guide for all those involved in the design, development, and administration of antimalarial drugs, including student academic researchers, medicinal chemists, malaria researchers, and pharmaceutical scientists. Consolidates both past and current developments in the discovery and design of antimalarial drugs Presents content in a style that is both thorough and engaging, providing a supportive and guiding reference to students and researchers from interdisciplinary backgrounds Highlights drug targets currently considered to be the most promising for future therapies, and the classes of compounds that are currently being studied and perfected

The Malaria Project

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Author :
Publisher : Penguin
ISBN 13 : 0698140133
Total Pages : 494 pages
Book Rating : 4.6/5 (981 download)

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Book Synopsis The Malaria Project by : Karen M. Masterson

Download or read book The Malaria Project written by Karen M. Masterson and published by Penguin. This book was released on 2014-10-07 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: A fascinating and shocking historical exposé, The Malaria Project is the story of America's secret mission to combat malaria during World War II—a campaign modeled after a German project which tested experimental drugs on men gone mad from syphilis. American war planners, foreseeing the tactical need for a malaria drug, recreated the German model, then grew it tenfold. Quickly becoming the biggest and most important medical initiative of the war, the project tasked dozens of the country’s top research scientists and university labs to find a treatment to remedy half a million U.S. troops incapacitated by malaria. Spearheading the new U.S. effort was Dr. Lowell T. Coggeshall, the son of a poor Indiana farmer whose persistent drive and curiosity led him to become one of the most innovative thinkers in solving the malaria problem. He recruited private corporations, such as today's Squibb and Eli Lilly, and the nation’s best chemists out of Harvard and Johns Hopkins to make novel compounds that skilled technicians tested on birds. Giants in the field of clinical research, including the future NIH director James Shannon, then tested the drugs on mental health patients and convicted criminals—including infamous murderer Nathan Leopold. By 1943, a dozen strains of malaria brought home in the veins of sick soldiers were injected into these human guinea pigs for drug studies. After hundreds of trials and many deaths, they found their “magic bullet,” but not in a U.S. laboratory. America 's best weapon against malaria, still used today, was captured in battle from the Nazis. Called chloroquine, it went on to save more lives than any other drug in history. Karen M. Masterson, a journalist turned malaria researcher, uncovers the complete story behind this dark tale of science, medicine and war. Illuminating, riveting and surprising, The Malaria Project captures the ethical perils of seeking treatments for disease while ignoring the human condition.

Malaria and Its Treatment in the Line and at the Base

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Author :
Publisher :
ISBN 13 :
Total Pages : 356 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Malaria and Its Treatment in the Line and at the Base by : Arthur Cecil Alport

Download or read book Malaria and Its Treatment in the Line and at the Base written by Arthur Cecil Alport and published by . This book was released on 1919 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Global Technical Strategy for Malaria 2016-2030

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Publisher : World Health Organization
ISBN 13 : 9241564997
Total Pages : 35 pages
Book Rating : 4.2/5 (415 download)

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Book Synopsis Global Technical Strategy for Malaria 2016-2030 by : World Health Organization

Download or read book Global Technical Strategy for Malaria 2016-2030 written by World Health Organization and published by World Health Organization. This book was released on 2015-11-04 with total page 35 pages. Available in PDF, EPUB and Kindle. Book excerpt: The World Health Organization's Global Technical Strategy for Malaria 2016- 2030 has been developed with the aim to help countries to reduce the human suffering caused by the world's deadliest mosquito-borne disease. Adopted by the World Health Assembly in May 2015 it provides comprehensive technical guidance to countries and development partners for the next 15 years emphasizing the importance of scaling up malaria responses and moving towards elimination. It also highlights the urgent need to increase investments across all interventions - including preventive measures diagnostic testing treatment and disease surveillance- as well as in harnessing innovation and expanding research. By adopting this strategy WHO Member States have endorsed the bold vision of a world free of malaria and set the ambitious new target of reducing the global malaria burden by 90% by 2030. They also agreed to strengthen health systems address emerging multi-drug and insecticide resistance and intensify national cross-border and regional efforts to scale up malaria responses to protect everyone at risk.

Malaria

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Publisher : National Academies Press
ISBN 13 : 0309045274
Total Pages : 328 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Malaria by : Institute of Medicine

Download or read book Malaria written by Institute of Medicine and published by National Academies Press. This book was released on 1991-02-01 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Malaria is making a dramatic comeback in the world. The disease is the foremost health challenge in Africa south of the Sahara, and people traveling to malarious areas are at increased risk of malaria-related sickness and death. This book examines the prospects for bringing malaria under control, with specific recommendations for U.S. policy, directions for research and program funding, and appropriate roles for federal and international agencies and the medical and public health communities. The volume reports on the current status of malaria research, prevention, and control efforts worldwide. The authors present study results and commentary on the: Nature, clinical manifestations, diagnosis, and epidemiology of malaria. Biology of the malaria parasite and its vector. Prospects for developing malaria vaccines and improved treatments. Economic, social, and behavioral factors in malaria control.

Management of Severe Malaria

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Publisher :
ISBN 13 :
Total Pages : 94 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Management of Severe Malaria by : World Health Organization

Download or read book Management of Severe Malaria written by World Health Organization and published by . This book was released on 2012 with total page 94 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Malaria continues to be a major health problem in many parts of the world. Delay in treatment, especially of cases caused by P. falciparum - the species of the parasite that is the main cause of the severe forms of the disease - may result in rapid deterioration in the patient's condition, and in the development of life-threatening complications. Recognizing and promptly treating uncomplicated malaria is therefore of vital importance. This Handbook, an updated edition of the Management of Severe Malaria, provides new and revised practical guidance on the diagnosis and management of severe malaria. After outlining the necessary general nursing care, it considers possible complications, including coma, convulsions, severe anaemia, hypoglycaemia and pulmonary oedema, and gives specific and concise advice on their management. While intended primarily for clinical professionals and other health staff responsible for centres with inpatients facilities in malaria-endemic countries, it will also be of practical use to physicians in non-endemic areas, who increasingly have to deal with patients infected during visits to malarious areas."--Publisher's description.

Management of Severe Malaria

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Publisher : World Health Organization
ISBN 13 : 9241545232
Total Pages : 84 pages
Book Rating : 4.2/5 (415 download)

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Book Synopsis Management of Severe Malaria by : World Health Organization

Download or read book Management of Severe Malaria written by World Health Organization and published by World Health Organization. This book was released on 2000-04 with total page 84 pages. Available in PDF, EPUB and Kindle. Book excerpt: Malaria continues to be a major health problem in many parts of the world, with over 2,400 million people in 100 countries at risk of infection. This handbook is an updated edition of 'Management of severe and complicated malaria', providing practical guidance on the diagnosis and management of severe falciparum malaria, a form of the disease that can have life-threatening complications if treatment is delayed.

Current Topics and Emerging Issues in Malaria Elimination

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 1839684836
Total Pages : 336 pages
Book Rating : 4.8/5 (396 download)

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Book Synopsis Current Topics and Emerging Issues in Malaria Elimination by :

Download or read book Current Topics and Emerging Issues in Malaria Elimination written by and published by BoD – Books on Demand. This book was released on 2021-07-21 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Malaria is one of the most important tropical diseases in the history of the world. This vector-borne disease has been a significant cause of morbidity and mortality in tropical countries of Africa, Asia, and Latin America. As such, this book provides updated information on epidemiological and public health research of malaria conducted in the last decade. Over four sections, chapters discuss such topics as diagnosis, epidemiology and surveillance, policy and prevention, and vector control and vaccines.

Guidelines on Prevention of the Reintroduction of Malaria

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Author :
Publisher : World Health Organization
ISBN 13 : 9290215771
Total Pages : 51 pages
Book Rating : 4.2/5 (92 download)

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Book Synopsis Guidelines on Prevention of the Reintroduction of Malaria by : World Health Organization. Regional Office for the Eastern Mediterranean

Download or read book Guidelines on Prevention of the Reintroduction of Malaria written by World Health Organization. Regional Office for the Eastern Mediterranean and published by World Health Organization. This book was released on 2007 with total page 51 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many countries have succeeded in eliminating malaria from their territories. However, they are still at risk of reintroduction from endemic countries and areas. The malaria programs in these countries face many challenges for prevention of malaria reintroduction, including weak malaria surveillance and vigilance systems, lack of malaria awareness among health professionals and travelers, uncontrolled population movement and lack of cooperation among countries. In the WHO Eastern Mediterranean Region 13 countries either eliminated malaria many years ago or are very close to malaria elimination. The main priority for these countries is to prevent re-establishment of local malaria transmission in receptive and vulnerable areas in their territories. These guidelines on prevention of reintroduction of malaria provide information on malaria surveillance and vigilance, malaria early warning system, prevention and control of re-introduced malaria, emergency preparedness for malaria outbreaks and monitoring, and evaluation of activities. The publication is targeted at policy and decision makers, health authorities responsible for malaria at national and sub-national levels and field staff. It can also be used in training courses on planning and management of malaria elimination.

Malaria

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 9780471931003
Total Pages : 246 pages
Book Rating : 4.9/5 (31 download)

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Book Synopsis Malaria by : G. A. T. Targett

Download or read book Malaria written by G. A. T. Targett and published by John Wiley & Sons. This book was released on 1991 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: Malaria Waiting for the Vaccine Edited by G.A.T. Targett, London School of Hygiene and Tropical Medicine Malaria affects enormous populations in tropical and sub-tropical areas of the world. In global terms,the situation is worsening as the impact of parasite and mosquito vector adaptations to drugs and insecticides exacerbates weaknesses in control programmes already under great strain for socio-economic reasons. This book, the first in a series of annual public health from the London School of Hygiene and Tropical Medicine, brings together expertise in all of the disciplines that impinge on current control efforts and that are essential for the development of new and improved measures. The ten sections provide a balance between the different approaches to public health management of malaria,those concerned with the individual who is infected, and control at community level. Clinical control emphasizes management of severe disease and the impact of drug resistance. Community public health measures consider all aspects of vector control, use and supply of drugs in endemic regions, and the organization and economics of control. For the future, the current status of vaccine development and the conduct of field trials are assessed. Detailed discussions amongst experts in each field lead to a series of recommendations designed to assist those currently engaged in control and management of the disease, to indicate priorities for future research, and above all to provide an agenda for national and international discussion on future strategies for combating the disease. The book will also appeal to epidemiologists, research scientists and clinicians as it sets their research and responsibilities in a much wider context than normal. In a similar way it will be invaluable for postgraduate teaching.