Magnetic Resonance Spectroscopy In Multiple Sclerosis

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Magnetic Resonance Spectroscopy in Multiple Sclerosis

Author : M. Filippi
Publisher : Springer Science & Business Media
ISBN 13 : 884702109X
Total Pages : 180 pages
Book Rating : 4.8/5 (47 download)

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Book Synopsis Magnetic Resonance Spectroscopy in Multiple Sclerosis by : M. Filippi

Download or read book Magnetic Resonance Spectroscopy in Multiple Sclerosis written by M. Filippi and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent years have witnessed dramatic advances in the development and use of magnetic resonance imaging (MRI) techniques that can provide quantitative measures with some degree of pathological specificity for the heterogeneous substrates of multiple sclerosis (MS). Magnetic resonance spectroscopy (MRS) is one of the most promising of these techniques. Thanks to MRS, axonal damage is no longer considered an end-stage phenomenon typical of only the most destructive lesions and the most unfortunate cases, but rather as a major component of the MS pathology of lesions and normal-appearing white matter at all the phases of the disease. This new concept is rapidly changing our understanding of MS pathophysiology and, as a consequence, the therapeutic strategies to modify the disease course favorably. Many of the authors have pionereed the use of MRS in MS, thus contributing to the foundation of the "axonal hypothesis".

New Frontiers of MR-based Techniques in Multiple Sclerosis

Author : Massimo Filippi
Publisher : Springer Science & Business Media
ISBN 13 : 8847022371
Total Pages : 174 pages
Book Rating : 4.8/5 (47 download)

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Book Synopsis New Frontiers of MR-based Techniques in Multiple Sclerosis by : Massimo Filippi

Download or read book New Frontiers of MR-based Techniques in Multiple Sclerosis written by Massimo Filippi and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past few years there have been impressive advances in the implementation of modern MRI techniques for the assessment of MS patients with the ultimate goal to define MRI markers of MS evolution. The authors of this volume not only review these new techniques, such as magnetization transfer (MT) MRI, diffusion-weighted (DW) MRI and proton MR spectroscopy (MRS), that are increasingly being used to monitor MS evolution, but also those, such as functional MRI (fMRI), cell-specific MRI, perfusion MRI, and microscopic imaging with ultra-high field MRI, that are emerging as additional promising tools for improving our understanding of MS pathophysiology. Strengths and weaknesses of all these modern quantitative MRI techniques for the study of MS are extensively covered in this book. The book also provides a valuable summary of the state of the art.

MR Spectroscopy of the Brain

Author : Lara Alexandre Brandão
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 0781746167
Total Pages : 426 pages
Book Rating : 4.7/5 (817 download)

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Book Synopsis MR Spectroscopy of the Brain by : Lara Alexandre Brandão

Download or read book MR Spectroscopy of the Brain written by Lara Alexandre Brandão and published by Lippincott Williams & Wilkins. This book was released on 2004 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is a practical guide to the technique and most frequent clinical applications of magnetic resonance spectroscopy (MRS) of the brain. Using more than 500 images, the authors present the fundamentals of MRS in a straightforward fashion and show radiologists and neurologists how to recognize normal and disease processes on scans. The book presents the spectra of the most common neurological disease entities, along with the conventional images and perfusion and diffusion where appropriate. The authors thoroughly describe the pathology and key MRS features of each disease process. Each chapter ends with a quick-reference summary of the main findings.

Magnetic Resonance Spectroscopy and Imaging in Neurochemistry

Author : Herman Bachelard
Publisher : Springer Science & Business Media
ISBN 13 : 1461558638
Total Pages : 427 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Magnetic Resonance Spectroscopy and Imaging in Neurochemistry by : Herman Bachelard

Download or read book Magnetic Resonance Spectroscopy and Imaging in Neurochemistry written by Herman Bachelard and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Advances in Neurochemistry series was initiated for a readership of neuroscientists with a background in biochemistry. True to this concept, the present volume brings together various applications of magnetic resonance technology to advance our knowledge of how the nervous system functions. Whether at the cellular, tissue slice, or intact organism level. magnetic resonance techniques are by their nature noninvasive, and thus provide a window through which biochemical reactions can be viewed without grinding, binding, or other wise perturbing ongoing physiological processes. As technological improve ments in methodology, such as higher and more uniform magnetic fields, novel paradigms for data analysis, etc. , are made, we find increased sensitivity and improved temporal and spatial resolution for functional imaging techniques on the one hand, and better separation of signals that identify chemical properties in spectral shift studies, on the other. It is upon knowledge such as is described in the twelve chapters that follow, that further advances in scientific discovery and the biomedical applications of tomorrow will be based. We are grateful to Dr. Bachelard, the Volume Editor, and to the authors of the individual chapters for their efforts. We also note that with this volume Dr. Morris Aprison, a co-founder of the Advances in Neurochemistry series has stepped down and acknowledge with thanks his major role in its inception. In addition, we thank our past and present Advisory Editors. Bernard W. Agranoff Kunihiko Suzuki Series Editors ix CONTENTS LIST OF SYMBOLS AND GLOSSARY . . . . . . . . . . . . . . . . . . . . . . . . . . . XXI INTRODUCTION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Clinical MR Spectroscopy

Author : Peter B. Barker
Publisher : Cambridge University Press
ISBN 13 : 052186898X
Total Pages : 275 pages
Book Rating : 4.5/5 (218 download)

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Book Synopsis Clinical MR Spectroscopy by : Peter B. Barker

Download or read book Clinical MR Spectroscopy written by Peter B. Barker and published by Cambridge University Press. This book was released on 2010 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covers all MR spectroscopy techniques and their clinical applications in neurological disorders, malignancies and musculoskeletal diseases.

Magnetic Resonance in Multiple Sclerosis

Author : David H. Miller
Publisher : Cambridge University Press
ISBN 13 : 9780521473255
Total Pages : 216 pages
Book Rating : 4.4/5 (732 download)

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Book Synopsis Magnetic Resonance in Multiple Sclerosis by : David H. Miller

Download or read book Magnetic Resonance in Multiple Sclerosis written by David H. Miller and published by Cambridge University Press. This book was released on 1997-07-17 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetic resonance (MR) imaging and spectroscopy are powerful tools for demonstrating and monitoring pathological processes of the brain and spinal cord. Multiple sclerosis (MS), a common and as yet incurable disease of the brain and spinal cord, is being studied intensively using these techniques. They perform a major role in facilitating the diagnosis, understanding the mechanisms of symptoms, and monitoring the effect of new treatments. Written by experts in the field, this extensively illustrated text provides a comprehensive review of the benefits and limitations of MR in the study of MS. Coverage ranges through the contributions of MR, the variety of techniques available, diagnosis and differential diagnosis, MR as a predictor of the clinical course, MR views of pathophysiology, and finally monitoring new treatment efficacy.

Quantitative Magnetic Resonance Imaging

Author : Nicole Seiberlich
Publisher : Academic Press
ISBN 13 : 0128170581
Total Pages : 1094 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Quantitative Magnetic Resonance Imaging by : Nicole Seiberlich

Download or read book Quantitative Magnetic Resonance Imaging written by Nicole Seiberlich and published by Academic Press. This book was released on 2020-11-18 with total page 1094 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quantitative Magnetic Resonance Imaging is a ‘go-to’ reference for methods and applications of quantitative magnetic resonance imaging, with specific sections on Relaxometry, Perfusion, and Diffusion. Each section will start with an explanation of the basic techniques for mapping the tissue property in question, including a description of the challenges that arise when using these basic approaches. For properties which can be measured in multiple ways, each of these basic methods will be described in separate chapters. Following the basics, a chapter in each section presents more advanced and recently proposed techniques for quantitative tissue property mapping, with a concluding chapter on clinical applications. The reader will learn: The basic physics behind tissue property mapping How to implement basic pulse sequences for the quantitative measurement of tissue properties The strengths and limitations to the basic and more rapid methods for mapping the magnetic relaxation properties T1, T2, and T2* The pros and cons for different approaches to mapping perfusion The methods of Diffusion-weighted imaging and how this approach can be used to generate diffusion tensor maps and more complex representations of diffusion How flow, magneto-electric tissue property, fat fraction, exchange, elastography, and temperature mapping are performed How fast imaging approaches including parallel imaging, compressed sensing, and Magnetic Resonance Fingerprinting can be used to accelerate or improve tissue property mapping schemes How tissue property mapping is used clinically in different organs Structured to cater for MRI researchers and graduate students with a wide variety of backgrounds Explains basic methods for quantitatively measuring tissue properties with MRI - including T1, T2, perfusion, diffusion, fat and iron fraction, elastography, flow, susceptibility - enabling the implementation of pulse sequences to perform measurements Shows the limitations of the techniques and explains the challenges to the clinical adoption of these traditional methods, presenting the latest research in rapid quantitative imaging which has the possibility to tackle these challenges Each section contains a chapter explaining the basics of novel ideas for quantitative mapping, such as compressed sensing and Magnetic Resonance Fingerprinting-based approaches

Magnetic Resonance Spectroscopy

Author : Charlotte Stagg
Publisher : Academic Press
ISBN 13 : 0124016979
Total Pages : 376 pages
Book Rating : 4.1/5 (24 download)

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Book Synopsis Magnetic Resonance Spectroscopy by : Charlotte Stagg

Download or read book Magnetic Resonance Spectroscopy written by Charlotte Stagg and published by Academic Press. This book was released on 2013-11-11 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetic Resonance Spectroscopy: Tools for Neuroscience Research and Emerging Clinical Applications is the first comprehensive book for non-physicists that addresses the emerging and exciting technique of magnetic resonance spectroscopy. Divided into three sections, this book provides coverage of the key areas of concern for researchers. The first, on how MRS is acquired, provides a comprehensive overview of the techniques, analysis, and pitfalls encountered in MRS; the second, on what can be seen by MRS, provides essential background physiology and biochemistry on the major metabolites studied; the final sections, on why MRS is used, constitutes a detailed guide to the major clinical and scientific uses of MRS, the current state of teh art, and recent innovations. Magnetic Resonance Spectroscopy will become the essential guide for people new to the technique and give those more familiar with MRS a new perspective. Chapters written by world-leading experts in the field Fully illustrated Covers both proton and non-proton MRS Includes the background to novel MRS imaging approaches

Magnetic Resonance Spectroscopy Diagnosis of Neurological Diseases

Author : Else Rubaek Danielsen
Publisher : CRC Press
ISBN 13 : 1482270102
Total Pages : 344 pages
Book Rating : 4.4/5 (822 download)

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Book Synopsis Magnetic Resonance Spectroscopy Diagnosis of Neurological Diseases by : Else Rubaek Danielsen

Download or read book Magnetic Resonance Spectroscopy Diagnosis of Neurological Diseases written by Else Rubaek Danielsen and published by CRC Press. This book was released on 1999-02-16 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Demonstrates how MRS offers a useful tool for the noninvasive biochemical analysis of the brain. The book covers over 70 clinical cases and more than 100 spectra that enhance skills at interpreting MRS, including minimizing errors, highlighting artifacts, and expanding the clinical usefulness of this diagnostic modality.

Magnetic Resonance Techniques in Clinical Trials in Multiple Sclerosis

Author : M. Filippi
Publisher : Springer Science & Business Media
ISBN 13 : 8847021537
Total Pages : 200 pages
Book Rating : 4.8/5 (47 download)

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Book Synopsis Magnetic Resonance Techniques in Clinical Trials in Multiple Sclerosis by : M. Filippi

Download or read book Magnetic Resonance Techniques in Clinical Trials in Multiple Sclerosis written by M. Filippi and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: We have entered an exciting period in the study of multiple sclerosis and its treatment. Central to this progress has been the introduction of magnetic reso nance techniques. When Young and his colleagues published the first images of the brain in multiple sclerosis at the end of 1981, it was at once obvious that magnetic resonance imaging would playa major role in diagnosis. Intuitively one felt that it would also have a role in increasing our understanding of the pathogenesis of the disease and in monitoring treatment. And so it has proved. Important problems however remain, perhaps the most important of which at present is the weak predictive power of standard magnetic resonance ima ging methods in determining the possibility of progression of impairment and disability. Recently, there have been advances which promise to overcome some of these problems, but decisions about what approach to adopt in selecting patients for clinical trials and which techniques to use in monitoring treatment during their course are still difficult. In this book, Dr. Filippi and his colleagues have assembled an outstanding group of contributors whose work is central to the progress that is being made. The coverage of the issues involved in the use of magnetic resonance techniques in assessing therapeutic effect is comprehensive and, though the field is chan ging rapidly, the principles and much of the detail in the book are likely to have lasting value.

Magnetic Resonance Spectroscopy

Author : Dong-Hyun Kim
Publisher : BoD – Books on Demand
ISBN 13 : 9535100653
Total Pages : 278 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Magnetic Resonance Spectroscopy by : Dong-Hyun Kim

Download or read book Magnetic Resonance Spectroscopy written by Dong-Hyun Kim and published by BoD – Books on Demand. This book was released on 2012-03-02 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetic Resonance Spectroscopy (MRS) is a unique tool to probe the biochemistry in vivo providing metabolic information non-invasively. Applications using MRS has been found over a broad spectrum in investigating the underlying structures of compounds as well as in determining disease states. In this book, topics of MRS both relevant to the clinic and also those that are beyond the clinical arena are covered. The book consists of two sections. The first section is entitled 'MRS inside the clinic' and is focused on clinical applications of MRS while the second section is entitled 'MRS beyond the clinic' and discusses applications of MRS in other academic fields. Our hope is that through this book, readers can understand the broad applications that NMR and MRS can offer and also that there are enough references to guide the readers for further study in this important topic.

1H Magnetic Resonance Spectroscopy in the Investigation of Multiple Sclerosis and Other Disorders of White Matter

Author : Charles Anthony Davie
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (181 download)

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Book Synopsis 1H Magnetic Resonance Spectroscopy in the Investigation of Multiple Sclerosis and Other Disorders of White Matter by : Charles Anthony Davie

Download or read book 1H Magnetic Resonance Spectroscopy in the Investigation of Multiple Sclerosis and Other Disorders of White Matter written by Charles Anthony Davie and published by . This book was released on 1997 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

In Vivo NMR Spectroscopy

Author : Robin A. de Graaf
Publisher : John Wiley & Sons
ISBN 13 : 1119382548
Total Pages : 584 pages
Book Rating : 4.1/5 (193 download)

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Book Synopsis In Vivo NMR Spectroscopy by : Robin A. de Graaf

Download or read book In Vivo NMR Spectroscopy written by Robin A. de Graaf and published by John Wiley & Sons. This book was released on 2019-03-11 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents basic concepts, experimental methodology and data acquisition, and processing standards of in vivo NMR spectroscopy This book covers, in detail, the technical and biophysical aspects of in vivo NMR techniques and includes novel developments in the field such as hyperpolarized NMR, dynamic 13C NMR, automated shimming, and parallel acquisitions. Most of the techniques are described from an educational point of view, yet it still retains the practical aspects appreciated by experimental NMR spectroscopists. In addition, each chapter concludes with a number of exercises designed to review, and often extend, the presented NMR principles and techniques. The third edition of In Vivo NMR Spectroscopy: Principles and Techniques has been updated to include experimental detail on the developing area of hyperpolarization; a description of the semi-LASER sequence, which is now a method of choice; updated chemical shift data, including the addition of 31P data; a troubleshooting section on common problems related to shimming, water suppression, and quantification; recent developments in data acquisition and processing standards; and MatLab scripts on the accompanying website for helping readers calculate radiofrequency pulses. Provide an educational explanation and overview of in vivo NMR, while maintaining the practical aspects appreciated by experimental NMR spectroscopists Features more experimental methodology than the previous edition End-of-chapter exercises that help drive home the principles and techniques and offer a more in-depth exploration of quantitative MR equations Designed to be used in conjunction with a teaching course on the subject In Vivo NMR Spectroscopy: Principles and Techniques, 3rd Edition is aimed at all those involved in fundamental and/or diagnostic in vivo NMR, ranging from people working in dedicated in vivo NMR institutes, to radiologists in hospitals, researchers in high-resolution NMR and MRI, and in areas such as neurology, physiology, chemistry, and medical biology.

MR Spectroscopy of the Brain, An Issue of Neuroimaging Clinics

Author : Lara A. Brandao
Publisher : Elsevier Health Sciences
ISBN 13 : 0323186297
Total Pages : 390 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis MR Spectroscopy of the Brain, An Issue of Neuroimaging Clinics by : Lara A. Brandao

Download or read book MR Spectroscopy of the Brain, An Issue of Neuroimaging Clinics written by Lara A. Brandao and published by Elsevier Health Sciences. This book was released on 2013-08-28 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue focuses on MR Spectroscopy (MRS) for neuroimaging. Topics include MRS for Common Dementias, Epilepsy, Metabolic Disorders, Hypoxic-isquemic Injuries, Multiple Sclerosis, Brain Infections, Pediatric Brain Tumors, Adult Brain Neoplasms.

In-vivo Human Spinal Cord and Brain Magnetic Resonance Spectroscopy in Multiple Sclerosis and Spinal Cord Injury Patients

Author : Patrik O. Wyss
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (14 download)

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Book Synopsis In-vivo Human Spinal Cord and Brain Magnetic Resonance Spectroscopy in Multiple Sclerosis and Spinal Cord Injury Patients by : Patrik O. Wyss

Download or read book In-vivo Human Spinal Cord and Brain Magnetic Resonance Spectroscopy in Multiple Sclerosis and Spinal Cord Injury Patients written by Patrik O. Wyss and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Multiple Sclerosis

Author : Michael Olek
Publisher : Springer Science & Business Media
ISBN 13 : 1592598552
Total Pages : 253 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Multiple Sclerosis by : Michael Olek

Download or read book Multiple Sclerosis written by Michael Olek and published by Springer Science & Business Media. This book was released on 2007-10-27 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: A synthesis of current concepts about the evaluation, treatment, and future directions in MS. On the evaluation side, the authors review the use of MRI, magnetic resonance spectroscopy, functional MRI, and three-dimensional MRI, and consider the rapidly developing body of pathologic information they have yielded. On the treatment side, the focus is on recently approved medications (Novantrone), new indications for medications (CHAMPS Trial), medications in development (Oral Interferon Tau, Oral Copaxone, and Oral Cellcept), immunosuppressive therapy for both progressive disease and symptomatic therapy; the current medications for treating relapsing-remitting MS (Avonex, Betaseron, and Copaxone) are also discussed. For future directions, the authors present the current best thinking, as well as the latest discoveries in immunology relating to MS, including groundbreaking B-cell research and its applications to specific immunotherapies, and the use of immune markers for tracking the disease.

Neuroimaging in Developmental Clinical Neuroscience

Author : Judith M. Rumsey
Publisher : Cambridge University Press
ISBN 13 : 1139476750
Total Pages : 473 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Neuroimaging in Developmental Clinical Neuroscience by : Judith M. Rumsey

Download or read book Neuroimaging in Developmental Clinical Neuroscience written by Judith M. Rumsey and published by Cambridge University Press. This book was released on 2009-02-19 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern neuroimaging offers tremendous opportunities for gaining insights into normative development and a wide array of developmental neuropsychiatric disorders. Focusing on ontogeny, this text covers basic processes involved in both healthy and atypical maturation, and also addresses the range of neuroimaging techniques most widely used for studying children. This book will enable you to understand normative structural and functional brain maturation and the mechanisms underlying basic developmental processes; become familiar with current knowledge and hypotheses concerning the neural bases of developmental neuropsychiatric disorders; and learn about neuroimaging techniques, including their unique strengths and limitations. Coverage includes normal developmental processes, atypical processing in developmental neuropsychiatric disorders, ethical issues, neuroimaging techniques and their integration with psychopharmacologic and molecular genetic research approaches, and future directions. This comprehensive volume is an essential resource for neurologists, neuropsychologists, psychiatrists, pediatricians, and radiologists concerned with normal development and developmental neuropsychiatric disorders.