Living Morphogenesis Of The Heart

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Living Morphogenesis of the Heart

Author : Roger Markwald
Publisher : Springer Science & Business Media
ISBN 13 : 1461217881
Total Pages : 245 pages
Book Rating : 4.4/5 (612 download)

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Book Synopsis Living Morphogenesis of the Heart by : Roger Markwald

Download or read book Living Morphogenesis of the Heart written by Roger Markwald and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: The overall scope of this new series will be to evolve an understanding of the genetic basis of (1) how early mesoderm commits to cells of a heart lineage that progres sively and irreversibly assemble into a segmented, primary heart tube that can be remodeled into a four-chambered organ, and (2) how blood vessels are derived and assembled both in the heart and in the body. Our central aim is to establish a four-dimensional, spatiotemporal foundation for the heart and blood vessels that can be genetically dissected for function and mechanism. Since Robert DeHaan's seminal chapter "Morphogenesis of the Vertebrate Heart" published in Organogenesis (Holt Rinehart & Winston, NY) in 1965, there have been surprisingly few books devoted to the subject of cardiovascular morpho genesis, despite the enormous growth of interest that occurred nationally and internationally. Most writings on the subject have been scholarly compilations of the proceedings of major national or international symposia or muItiauthored volumes, often without a specific theme. What is missing are the unifying concepts that can make sense out of a burgeoning database of facts. The Editorial Board of this new series believes the time has come for a book series dedicated to cardiovas cular morphogenesis that will serve not only as an important archival and didactic reference source for those who have recently come into the field but also as a guide to the evolution of a field that is clearly coming of age.

Living Morphogenesis of the Heart

Author : María Victoria De la Cruz
Publisher : Birkhauser
ISBN 13 : 9783764340377
Total Pages : 233 pages
Book Rating : 4.3/5 (43 download)

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Book Synopsis Living Morphogenesis of the Heart by : María Victoria De la Cruz

Download or read book Living Morphogenesis of the Heart written by María Victoria De la Cruz and published by Birkhauser. This book was released on 1998-01-01 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: As perhaps the first text to present heart development from a living morphogenetic perspective, photographs of an in vivo experiment in the chick embryo heart grace the cover of this compilation of ten chapters by as many Pan-American contributors summarizing current knowledge in the field. Offering new data from Dr. de la Cruz's work, chapters elucidate: e.g. formation and septation of the tubular heart: integrating the dynamics of morphology with emerging molecular concepts, embryological development of the ventricular inlets, and primitive cardiac segment: the normal heart and heart diseases. Three-dimensional scanning electron micrographs (some in color) enhance the text. The other title in the new series is Vascular Morphogenesis: in vivo, in vitro, in mente (ed. by C.D. Little, et al.). Annotation copyrighted by Book News, Inc., Portland, OR

Etiology and Morphogenesis of Congenital Heart Disease

Author : Richard Van Praagh
Publisher : Wiley-Blackwell
ISBN 13 :
Total Pages : 566 pages
Book Rating : 4.:/5 (43 download)

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Book Synopsis Etiology and Morphogenesis of Congenital Heart Disease by : Richard Van Praagh

Download or read book Etiology and Morphogenesis of Congenital Heart Disease written by Richard Van Praagh and published by Wiley-Blackwell. This book was released on 1980 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Etiology and Morphogenesis of Congenital Heart Disease

Author : Toshio Nakanishi
Publisher : Springer
ISBN 13 : 4431546286
Total Pages : 367 pages
Book Rating : 4.4/5 (315 download)

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Book Synopsis Etiology and Morphogenesis of Congenital Heart Disease by : Toshio Nakanishi

Download or read book Etiology and Morphogenesis of Congenital Heart Disease written by Toshio Nakanishi and published by Springer. This book was released on 2016-06-24 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume focuses on the etiology and morphogenesis of congenital heart diseases. It reviews in detail the early development and differentiation of the heart, and later morphologic events of the cardiovascular system, covering a wide range of topics such as gene functions, growth factors, transcription factors and cellular interactions that are implicated in cardiac morphogenesis and congenital heart disease. This book also presents recent advances in stem cell and cell sheet tissue engineering technologies which have the potential to provide novel in vitro disease models and to generate regenerative paradigms for cardiac repair and regeneration. This is the ideal resource for physician scientists and investigators looking for updates on recent investigations on the origins of congenital heart disease and potential future therapies.

Heart Development

Author : Richard P. Harvey
Publisher : Gulf Professional Publishing
ISBN 13 : 9780123298607
Total Pages : 574 pages
Book Rating : 4.2/5 (986 download)

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Book Synopsis Heart Development by : Richard P. Harvey

Download or read book Heart Development written by Richard P. Harvey and published by Gulf Professional Publishing. This book was released on 1999 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contributors. -- Preface. -- C. Seidman, Introduction. -- I. Origins and Early Morphogenesis: -- P.P.L. Tam and G.C. Schoenwolf, Cardiac Fate Maps: Lineage Allocation, Morphogenetic Movement, and Cell Commitment. -- T. Mikawa, Cardiac Lineages. -- II. Cardiac Induction: -- T.J. Mohun and L.M. Leong, Heart Formation and the Heart Field in Amphibian Embryos. -- T.M. Schultheiss and A.B. Lassar, Vertebrate Heart Induction. -- III. Genetic Dissection of Heart Development: -- R. Bodmer and M. Frasch, Genetic Determination in Drosophilia Heart Development. -- J. Alexander and D.Y.R. Stainier, Mutations Affecting Cardiac Development in Zebrafish. -- R.P. Harvey, C. Biben, and D.A. Elliott, Transcriptional Control and Pattern Formation in the Developing Vertebrate Heart: Studies on NK-2 Class Homeodomain Factors. -- B.L. Black and E.N. Olson, Control of Cardiac Development by the Family of MEF2 Transcription Factors. -- D. Srivastava, Segmental Regulation of Cardiac Development by the Basic He ...

Formation of the Heart and its Regulation

Author : Robert J. Tomanek
Publisher : Springer Science & Business Media
ISBN 13 : 1461202078
Total Pages : 290 pages
Book Rating : 4.4/5 (612 download)

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Book Synopsis Formation of the Heart and its Regulation by : Robert J. Tomanek

Download or read book Formation of the Heart and its Regulation written by Robert J. Tomanek and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: The `Formation of the Heart and its Regulation` reviews in considerable detail the major events in heart development and their control via genes, cell-cell interactions, growth factors and other contributing elements. In addition, there is an extensive and useful overview of the field of heart development taken as a whole. The book will appeal to all students and researchers working on cardiovascular development and to pediatric cardiologists.

Cardiac CT and MR for Adult Congenital Heart Disease

Author : Farhood Saremi
Publisher : Springer Science & Business Media
ISBN 13 : 1461488753
Total Pages : 735 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Cardiac CT and MR for Adult Congenital Heart Disease by : Farhood Saremi

Download or read book Cardiac CT and MR for Adult Congenital Heart Disease written by Farhood Saremi and published by Springer Science & Business Media. This book was released on 2013-11-22 with total page 735 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first major textbook to address both computed tomography (CT) and magnetic resonance (MR) cardiac imaging of adults for the diagnosis and treatment of congenital heart disease (CHD). Since the introduction of faster CT scanners, there has been tremendous advancement in the diagnosis of CHD in adults. This is mostly due to the higher spatial resolution of CT compared to MR, which enables radiologists to create more detailed visualizations of cardiac anatomic structures, leading to the discovery of anomalous pathologies often missed by conventional MR imaging. This book is unique in highlighting the advantages of both CT and MR for the diagnosis of CHD in adults, focusing on the complementary collaboration between the two modalities that is possible. Chapters include discussions of case examples, clinical data, MR and CT image findings, and correlative cadaveric pictures. The chapters focus not only on the diagnosis of the primary problem, but also give readers information on visual clues to look for that often reveal associated pathologies. This book appeals primarily to diagnostic and interventional radiologists, as well as cardiologists and interventional cardiologists.

Molecular Mechanism of Congenital Heart Disease and Pulmonary Hypertension

Author : Toshio Nakanishi
Publisher : Springer Nature
ISBN 13 : 9811511853
Total Pages : 374 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Molecular Mechanism of Congenital Heart Disease and Pulmonary Hypertension by : Toshio Nakanishi

Download or read book Molecular Mechanism of Congenital Heart Disease and Pulmonary Hypertension written by Toshio Nakanishi and published by Springer Nature. This book was released on 2020-02-28 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book focuses on the molecular mechanism of congenital heart disease and pulmonary hypertension, offering new insights into the development of pulmonary circulation and the ductus arteriosus. It describes in detail the molecular mechanisms involved in the development and morphogenesis of the heart, lungs and ductus arteriosus, covering a range of topics such as gene functions, growth factors, transcription factors and cellular interactions, as well as stem cell engineering technologies. The book also presents recent advances in our understanding of the molecular mechanism of lung development, pulmonary hypertension and molecular regulation of the ductus arteriosus. As such, it is an ideal resource for physicians, scientists and investigators interested in the latest findings on the origins of congenital heart disease and potential future therapies involving pulmonary circulation/hypertension and the ductus arteriosus.

Pathology of Heart Disease in the Fetus, Infant and Child

Author : Michael T. Ashworth
Publisher : Cambridge University Press
ISBN 13 : 1107116287
Total Pages : 361 pages
Book Rating : 4.1/5 (71 download)

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Book Synopsis Pathology of Heart Disease in the Fetus, Infant and Child by : Michael T. Ashworth

Download or read book Pathology of Heart Disease in the Fetus, Infant and Child written by Michael T. Ashworth and published by Cambridge University Press. This book was released on 2019-08-22 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clearly presents the pathology of heart disease from fetus to adolescence, integrating histology and macroscopy with effects of treatment.

Echocardiography in Pediatric and Congenital Heart Disease

Author : Wyman W. Lai
Publisher : John Wiley & Sons
ISBN 13 : 1118337255
Total Pages : 1618 pages
Book Rating : 4.1/5 (183 download)

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Book Synopsis Echocardiography in Pediatric and Congenital Heart Disease by : Wyman W. Lai

Download or read book Echocardiography in Pediatric and Congenital Heart Disease written by Wyman W. Lai and published by John Wiley & Sons. This book was released on 2012-01-03 with total page 1618 pages. Available in PDF, EPUB and Kindle. Book excerpt: Echocardiography is essential in the practice of pediatric cardiology. A clinical pediatric cardiologist is expected to be adept at the non-invasive diagnosis of congenital heart disease and those who plan to specialize in echocardiography will need to have knowledge of advanced techniques. Echocardiography in Pediatric and Congenital Heart Disease addresses the needs of trainees and practitioners in this field, filling a void caused by the lack of material in this fast-growing area. This new title comprehensively covers the echocardiographic assessment of congenital heart disease, from the fetus to the adult, plus acquired heart disease in children. Topics covered include: ultrasound physics laboratory set-up a protocol for a standard pediatric echocardiogram quantitative methods of echocardiographic evaluation, including assessment of diastolic function in depth coverage of congenital cardiovascular malformations acquired pediatric heart disease topics of special interest, such as 3D echocardiography, transesophageal echocardiography, and fetal echocardiography The approach of this book is a major advancement for educational materials in the field of pediatric cardiology, and greatly enhances the experience for the reader. An accompanying DVD with moving images of the subjects covered in the textbook will further enhance the learning experience.

Unraveling the Pathways of Cardiovascular Morphogenesis and Congenital Heart Defects Through Classical and Proteomic Studies

Author : Anjali Katyal Nath
Publisher :
ISBN 13 : 9780549068655
Total Pages : 139 pages
Book Rating : 4.0/5 (686 download)

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Book Synopsis Unraveling the Pathways of Cardiovascular Morphogenesis and Congenital Heart Defects Through Classical and Proteomic Studies by : Anjali Katyal Nath

Download or read book Unraveling the Pathways of Cardiovascular Morphogenesis and Congenital Heart Defects Through Classical and Proteomic Studies written by Anjali Katyal Nath and published by . This book was released on 2007 with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt: Congenital heart defects (CHDs), the most common congenital anomaly, affects ∼1% of live births in the United States. Further, over 1 million survivors of CHDs require continual clinical care. Progress in our understanding of the genetic and molecular events that underlie cardiovascular development have been derived from the ex vivo heart and whole embryo culture models and fortuitous transgenic mice with cardiovascular phenotypes. After decades of work with these models, the pathways that govern mammalian cardiovascular morphogenesis, though slowly being unraveled, are poorly understood. Advancements in the field have been hindered by the lengthy process of creating and breeding transgenic mice and the paucity of technological approaches amenable to the ex vivo model systems. Utilization of the ex vivo model requires the a priori knowledge of the molecules of interest and the availability of appropriate reagents to study a given factor (i.e. recombinant factors, inhibitors, antibodies or tissues from transgenic mice). Embryonic structures contain small amounts of protein which limits its use in biochemical assays. Further there is a lack of readily available homogeneous cell lines derived from the embryonic heart and vasculature to perform in vitro studies. To circumvent these methodological limitations, in addition to utilizing the classical ex vivo models, a proteomic approach was employed to determine protein profiles during normal and abnormal cardiovascular development and uncover proteins previously unappreciated to have a role in the cardiovascular system. Using these approaches several proteins were found to have novel roles in cardiovascular development including nitric oxide, leptin, Wnt16, ADAM15, NOGO, laminin 1, TRPC5, ST14 and PTPN1. The data accrued through these studies highlight the importance of antioxidant, adhesion/migration, differentiation and insulin like growth factor pathways in cardiovascular development. The successful application of these proteins (MMP2, laminin 1, Wnt16, PC1/3 and SVCT) as biomarkers of congenital heart defects was confirmed in both murine and human amniotic fluid samples. Discovery of novel proteins and pathways involved in cardiovascular development will broaden our understanding of the global developmental pathways of cardiovascular morphogenesis and the pathogenic mechanisms that underlie congenital heart defects in order to diagnose, prevent and treat CHDs in the future.

Mathematical Modelling of the Human Cardiovascular System

Author : Alfio Quarteroni
Publisher : Cambridge University Press
ISBN 13 : 110848039X
Total Pages : 291 pages
Book Rating : 4.1/5 (84 download)

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Book Synopsis Mathematical Modelling of the Human Cardiovascular System by : Alfio Quarteroni

Download or read book Mathematical Modelling of the Human Cardiovascular System written by Alfio Quarteroni and published by Cambridge University Press. This book was released on 2019-05-09 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: Addresses the mathematical and numerical modelling of the human cardiovascular system, from patient data to clinical applications.

Development of the Cardiac Conduction System

Author : Derek J. Chadwick
Publisher : John Wiley & Sons
ISBN 13 : 0470868031
Total Pages : 300 pages
Book Rating : 4.4/5 (78 download)

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Book Synopsis Development of the Cardiac Conduction System by : Derek J. Chadwick

Download or read book Development of the Cardiac Conduction System written by Derek J. Chadwick and published by John Wiley & Sons. This book was released on 2005-01-21 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: The pacemaking and conduction system (PCS) is vital for generating and synchronizing the heart beat. Dysfunction of this system can be a direct cause of cardiac conduction disturbance, arrhythmias and sudden cardiac death. A wealth of information has been collected over many years on the unique histological, morphological and phenotypic characteristics of specialized cardiac tissues. The cellular and molecular mechanisms that govern development of the PCS are now starting to be understood. This book draws together contributions from an international and interdisciplinary group of experts working on both basic and clinical aspects of cardiac development. It features reviews of the structure and function of the developing PCS, discussion of the molecular and cellular mechanisms regulating embryological development of this system and studies on the fundamental basis of PCS pathology. The book also considers how novel therapeutic interventions based on understanding of the developmental biology of cardiac pacemaking and conduction tissues might ultimately impact on clinical medicine.

Dynamic Imaging of Function and Morphogenesis in the Developing Heart

Author : Jungho Ohn
Publisher :
ISBN 13 : 9781303052613
Total Pages : 136 pages
Book Rating : 4.0/5 (526 download)

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Book Synopsis Dynamic Imaging of Function and Morphogenesis in the Developing Heart by : Jungho Ohn

Download or read book Dynamic Imaging of Function and Morphogenesis in the Developing Heart written by Jungho Ohn and published by . This book was released on 2013 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt: Congenital heart disease, the most common birth defect, occurs up to 5% of live births in humans. Understanding the relationship between morphology and function during development in the embryonic heart has important medical implications. Our studies focus on developing non-invasive heart imaging tools to observe the dynamics of morphogenesis while the heart is growing and functioning. Our approach consists in setting up a computer-driven automated microscope equipped with high-speed and sensitive cameras, implementing sample mounting protocols, and developing image reconstruction and analysis software. In order to improve the specificity with which structures can be imaged in the beating heart, we developed multi-modal microscopy by combining high-speed and multi-color sequences taken in brightfield and fluorescence microscopy, respectively. In an effort to improve axial resolution in conventional widefield microscopy, we implemented dynamic optical projection tomography. To quantify variability when characterizing heart function, we developed in vivo high-throughput microscopy. Finally, we carried out joint and quantitative studies of heart morphogenesis and functiogenesis by use of a novel imaging technique, burst time-lapse microscopy (BTLM). This allowed building time-lapses revealing the morphogenesis of the highly dynamic cardiac valve leaflets as they progressively prevent retrograde flow between cardiac chambers. This work provides new insights into cardiogenesis and should allow better understanding of normal and diseased development. We anticipate that the developed tools will be applicable for imaging a wide range of dynamic biological samples.

Myofibrillogenesis

Author : Dipak K. Dube
Publisher : Springer Science & Business Media
ISBN 13 : 9780817642266
Total Pages : 304 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis Myofibrillogenesis by : Dipak K. Dube

Download or read book Myofibrillogenesis written by Dipak K. Dube and published by Springer Science & Business Media. This book was released on 2001-10-19 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Myofibrillogenesis has been studied extensively over the last 100 years. Until recently, we have not had a comprehensive understanding of this fundamental process. The emergence of new technologies in molecular and cellular biology, combined with classical embryology, have started to unravel some of the complexities of myofibril assembly in striated muscles. In striated muscles, the contractile proteins are arranged in a highly ordered three dimensional lattice known as the sarcomere. The assembly of a myofibril involves the precise ordering of several proteins into a linear array of sarcomeres. Multiple isoforms in many of these proteins further complicate the process, making it difficult to define the precise role of each component. This volume has been compiled as a comprehensive reference on myofibrillogenesis. In addition, the book includes reviews on myofibrillar disarray under various pathological conditions, such as familial hypertrophic cardiomyopathy (FHC), and incorporates a section on the conduction system in the heart. Much of the information in this volume has not been described elsewhere. Presented in a manner to be of value to students and teachers alike, "Myofibrillogenesis" will be an invaluable reference source for all in the fields of muscle biology and heart development.

Steding's and Virágh's Scanning Electron Microscopy Atlas of the Developing Human Heart

Author : R.J. Oostra
Publisher : Springer Science & Business Media
ISBN 13 : 0387682724
Total Pages : 218 pages
Book Rating : 4.3/5 (876 download)

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Book Synopsis Steding's and Virágh's Scanning Electron Microscopy Atlas of the Developing Human Heart by : R.J. Oostra

Download or read book Steding's and Virágh's Scanning Electron Microscopy Atlas of the Developing Human Heart written by R.J. Oostra and published by Springer Science & Business Media. This book was released on 2007-04-05 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: This atlas comprises a complete and extensive exposure of the spatial and temporal aspects of human cardiac development as seen with scanning electron microscopy. Apart from serving as a unique overview on cardiac development in the human embryo, this atlas gives an updated morphological reference of cardiac embryology for topographic correlation and enables the projection of experimental results in animals to the human situation.

The More Beautiful World Our Hearts Know Is Possible

Author : Charles Eisenstein
Publisher : North Atlantic Books
ISBN 13 : 1583947248
Total Pages : 289 pages
Book Rating : 4.5/5 (839 download)

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Book Synopsis The More Beautiful World Our Hearts Know Is Possible by : Charles Eisenstein

Download or read book The More Beautiful World Our Hearts Know Is Possible written by Charles Eisenstein and published by North Atlantic Books. This book was released on 2013-11-05 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: As seen on Oprah’s Super Soul Sunday A beacon of hope in the face of our current world crises, this uplifting book demonstrates how embracing our interconnectedness is key to world transformation In a time of social and ecological crisis, what can we as individuals do to make the world a better place? This inspirational and thought-provoking book serves as an empowering antidote to the cynicism, frustration, paralysis, and overwhelm so many of us are feeling, replacing it with a grounding reminder of what’s true: we are all connected, and our small, personal choices bear unsuspected transformational power. By fully embracing and practicing this principle of interconnectedness—called interbeing—we become more effective agents of change and have a stronger positive influence on the world. Throughout the book, Eisenstein relates real-life stories showing how small, individual acts of courage, kindness, and self-trust can change our culture’s guiding narrative of separation, which, he shows, has generated the present planetary crisis. He brings to conscious awareness a deep wisdom we all innately know: until we get ourselves in order, any action we take—no matter how good our intentions—will ultimately be wrong-headed and wrong-hearted. Above all, Eisenstein invites us to embrace a radically different understanding of cause and effect, sounding a clarion call to surrender our old worldview of separation, so that we can finally create the more beautiful world our hearts know is possible. With chapters covering separation, interbeing, despair, hope, pain, pleasure, consciousness, and many more, the book invites us to let the old Story of Separation fall away so that we can stand firmly in a Story of Interbeing.