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Lithium In Neuropsychiatry
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Book Synopsis Lithium in Neuropsychiatry by : Michael Bauer
Download or read book Lithium in Neuropsychiatry written by Michael Bauer and published by CRC Press. This book was released on 2006-05-23 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: The definitive textbook on the use of lithium in the treatment of mental disorders, this comprehensive work provides an up-to-date analysis of lithium, including: History Clinical applications, including its use for mania, bipolar and schizophrenic disorders Use in special populations, for example in children, the elderly and people with medical conditions The effect on the body and behavior, including neurological, gastrointestinal, cardiovascular and dermatological effects, as well as those relating to the kidneys and thyroid Basic findings in pharmacology, chemistry, transport in the body, pharmacokinetics, signal transduction pathways, immune function, gene regulation. Practical issues, such as guidelines for safe use, discontinuation issues, compliance, intoxication, and economics. Edited by top experts from the International Group for the Study of Lithium Treated Patients (IGSLi), Lithium in Neuropsychiatry: A Comprehensive Guide is a unique and vital resource for psychiatrists, psychopharmacologists, psychotherapists and neuroscientists.
Book Synopsis Lithium in Neuropsychiatry by : Michael Bauer
Download or read book Lithium in Neuropsychiatry written by Michael Bauer and published by CRC Press. This book was released on 2018-09-18 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: The definitive textbook on the use of lithium in the treatment of mental disorders, this comprehensive work provides an up-to-date analysis of lithium, including: History Clinical applications, including its use for mania, bipolar and schizophrenic disorders Use in special populations, for example in children, the elderly and people with medical conditions The effect on the body and behavior, including neurological, gastrointestinal, cardiovascular and dermatological effects, as well as those relating to the kidneys and thyroid Basic findings in pharmacology, chemistry, transport in the body, pharmacokinetics, signal transduction pathways, immune function, gene regulation. Practical issues, such as guidelines for safe use, discontinuation issues, compliance, intoxication, and economics. Edited by top experts from the International Group for the Study of Lithium Treated Patients (IGSLi), Lithium in Neuropsychiatry: A Comprehensive Guide is a unique and vital resource for psychiatrists, psychopharmacologists, psychotherapists and neuroscientists.
Book Synopsis The History of Lithium Therapy by : Frederick Neil Johnson
Download or read book The History of Lithium Therapy written by Frederick Neil Johnson and published by Springer. This book was released on 1984-06-18 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Lithium written by Samuel Gershon and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: Psychopharmacology has certainly had the greatest impact on psy chiatric theory and practice since the psychoanalytic discoveries by Freud. Beginning more than 20 years ago, psychopharmacology has become a vigorous interdisciplinary science, and over the last 10 to 15 years has witnessed a tremendous growth both from a scientific and practical point of view. Lithium occupies a unique and central position in modern psycho pharmacology for several reasons. The introduction of the lithium ion in 1949 as a psychoactive drug preceded the advent of reserpine or chlorprom azine and placed it as the first agent in the modern era of pharmacopsy chiatry. In fact, this first report on the use of lithium by an Australian clinician set a pattern to be followed for all other major groups of psychoac tive chemical agents. Unlike the now established antipsychotic and antidepressant drugs, however, no reliable predictions based on preclinical pharmacological studies were available about the profile of lithium's clinical activity. This problem of clinical predictability based on current preclinical pharmacological studies is now surfacing with the advent of many newer investigational psychoactive agents. As in the introduction of other therapeutic modalities in medicine, including psychiatry, serendipity was the midwife for lithium. The use of this ion in psychiatry, from its fortuitous introduction by Cade in 1949 to its present-day acceptance as a universal treatment modality in the affective emotional disorders, presents, however, a clear example of a hapless lag between discovery and application.
Book Synopsis The Essential Guide to Lithium Treatment by : Michael Bauer
Download or read book The Essential Guide to Lithium Treatment written by Michael Bauer and published by Springer. This book was released on 2016-05-19 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a practical, up-to-date guide to the correct use of lithium for the short- and long-term treatment of mood disorders. Among the subjects addressed are the pharmacology and mechanisms of action of lithium, its use for maintenance treatment, the role of lithium in the treatment of mania and depression and in suicide prevention, further clinical indications, the administration of lithium during pregnancy and the postpartum period, and adverse effects and their management. Relevant background information is provided on the diagnosis, classification, and natural course of mood disorders, and an overview of other treatments for bipolar disorder and major depression is included. Lithium is the essential medication for patients with mood disorders. The evidence of its efficacy in maintenance treatment is acknowledged in all major international treatment guidelines for bipolar disorders and, when used correctly, lithium unquestionably produces the most dramatic benefits of any medication in psychopharmacology. This essential guide is written by two international experts in the treatment of mood disorders who have more than 25 years of experience in the use of lithium and have authored numerous scientific articles on lithium.
Book Synopsis The Science and Practice of Lithium Therapy by : Gin S. Malhi
Download or read book The Science and Practice of Lithium Therapy written by Gin S. Malhi and published by Springer. This book was released on 2016-11-24 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a clear and comprehensive guide to the clinical prescription of lithium that draws upon evidence-based knowledge of its mechanisms of action. The book is divided into two parts, on the science of lithium and the practice of lithium therapy. The former covers aspects such as the properties of the lithium ion, pharmacokinetics and pharmacodynamics, impact on neurotransmission, and gene expression modulation. The section on practice includes discussion of variability in response to lithium, use of lithium in the treatment of bipolar disorders, its value in suicide prevention, administration during pregnancy and in the pediatric age group, and side effects. Lithium is arguably the only true mood stabilizer, and its multifaceted effects across many clinical domains have given rise to a resurgence of interest in recent years, fuelled by both researchers and clinicians. Nevertheless, its use remains constrained by exaggerated concerns about potential side-effects. In reality, lithium is a simple molecule that is relatively straightforward to administer and monitor and has potentially profound benefits at a fraction of the cost of contemporary agents. This book dispels the many myths and concerns that surround its use and will be of interest for clinicians and researchers worldwide, and those that are recipients of lithium therapy.
Download or read book Lithium written by Samuel Gershon and published by . This book was released on 1973 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Mental Health/mental Illness written by and published by . This book was released on 1993 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Lithium in the Treatment of Mood Disorders by : Antoinette A. Gattozzi
Download or read book Lithium in the Treatment of Mood Disorders written by Antoinette A. Gattozzi and published by . This book was released on 1970 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Use of Lithium in Psychiatry by : Barry Maletzky
Download or read book The Use of Lithium in Psychiatry written by Barry Maletzky and published by . This book was released on 1971 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Lithium in Psychiatry in Historical Perspective by : Jules Angst
Download or read book Lithium in Psychiatry in Historical Perspective written by Jules Angst and published by Inhn Publisher. This book was released on 2021-12-19 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lithium in Historical Perspective is a collection of selected papers from INHN's. To provide readily accessible information on the history of the substance, the postings are presented in eight chapters: 1. Discovery, 2. Introduction, 3. Verification, 4. Controversy, 5. Re-evaluation, 6. Safety, 7. Action and 8. Indications. The potential use of lithium in "mania" was discovered by William T. Hammond and in "periodic depression" by Carl Lange in the19th century. There are two postings relevant to this topic: Johan Schioldann's comment on William Hammond and Carl Lange's speech, "On Periodical Depressions and Their Pathogenesis," in Schioldann's translation from Danish into English. Instrumental to the introduction of lithium was Edward Trautner's determination of an effective dose range in which Lithium can be safely administered. There are four contributions relevant to this topic: John Cade's and Trautner's biographies, by Samuel Gershon; Gershon's autobiographic account, "Events and Memories"; and Gershon's "Lithium History." The therapeutic effect of Lithium in "mania" was verified by Mogens Schou in the mid-1950s. There are three relevant to this topic: Mogens Schou's autobiography, and Grof's and Rybakowski's comments on it. Acceptance of lithium was delayed by a controversy in the mid-1960s about its prophylactic effect. There are four contributions in the collection relevant to this topic: Barry Blackwell's essay, "The lithium controversy, a historical autopsy"; Paul Grof's and Jules Angst's comments on it; and Blackwell's reply to both. In the 1980s lithium was re-evaluated and its place in treatment consolidated. There are three papers on this topic: Grof's comment, "More hindsight thought," on Blackwell's comments on Schou's "My journey with lithium"; Blackwell's review of Schioldann's "History of the Introduction of Lithium into Medicine and Psychiatry: Birth of Modern Psychopharmacology 1949"; and Schioldann's comment on Blackwell's review. With the prolonged use of the substance its anti-vasopressin action, causing polyuria and nephrogenic diabetes insipidus in vulnerable patients had become a safety concern. Spearheaded by the research of Radó, by the end of the second decade of the 21st-century renal toxicity of lithium could be successfully treated and prevented. There are five essays by Radó included in this collection relevant to this topic: "Mechanism of lithium-induced polyuria in historical perspective"; "Calcitonin in nephrogenic diabetes insipidus"; "Renal toxicity of lithium in historical perspective with special reference to nephrogenic diabetes insipidus"; "Desmopressin may counteract polyuria in lithium-induced nephrogenic diabetes insipidus. Review of the literature"; and "Use of modern antidiuretic agents in lithium-induced nephrogenic diabetes insipidus." Throughout the years the mode of action of lithium has been extensively studied. Yet, in this selection, information on its possible mode of action is restricted to its effect on the "purinergic system" presented in two essays: Magda Malewska-Kasprzak, Agnieszka Permoda-Osip, and Rybakowski's treatise on the "Disturbances of the purinergic system in affective disorders and schizophrenia" and Rybakowski's "Additional information: A commentary on Walter Felber's paper on Lithium prevention of depression 100 years ago -- an ingenious misconception, published in 1987." The therapeutic indication of lithium extended after its introduction from the treatment of "manic excitement" to the acute, maintenance and prophylactic treatment of "manic-depressive psychosis," referred to by that time as "bipolar disorder" in consensus-based classifications. Finally, there are two essays by Thomas Ban: "Development of the diagnostic concept of Manic-Depressive Psychosis in Emil Kraepelin's classifications" and "From Emil Kraepelin's Manic-Depressive Psychosis to Karl Leonhard's Phasic and Cycloid
Book Synopsis Neuropsychiatry by : Randolph B. Schiffer
Download or read book Neuropsychiatry written by Randolph B. Schiffer and published by Lippincott Williams & Wilkins. This book was released on 2003 with total page 1302 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thoroughly revised Second Edition builds on the success of the first as the definitive text for neuropsychiatry. The book is divided into three sections, with the third on syndromes and disorders. Emphasis on treatment is provided throughout the text and is DSM-IV-compatible. Coverage includes neurobehavioral disorders, selection and interpretation of neurodiagnostic procedures, and the full spectrum of therapies. New to this edition are eight chapters and the incorporation of psychopharmacology into specific disease chapters. Compatibility: BlackBerry(R) OS 4.1 or Higher / iPhone/iPod Touch 2.0 or Higher /Palm OS 3.5 or higher / Palm Pre Classic / Symbian S60, 3rd edition (Nokia) / Windows Mobile(TM) Pocket PC (all versions) / Windows Mobile Smartphone / Windows 98SE/2000/ME/XP/Vista/Tablet PC
Book Synopsis Lithium Therapy: a Personal Tale of the Recent Decade by : Janusz Rybakowski
Download or read book Lithium Therapy: a Personal Tale of the Recent Decade written by Janusz Rybakowski and published by Eliva Press. This book was released on 2021-08-02 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lithium is a first choice mood-stabilizer for the maintenance treatment of bipolar disorder. The drug can augment antidepressants in treatment-resistant depression and exerts anti-suicidal, immunomodulatory, and neuroprotective action. For the author of this book, clinical use and mechanism of therapeutic action of lithium have been a leitmotiv since 1970. It resulted in multiple publications, and the book "Lithium - the amazing drug in psychiatry", published in 2020. Thirty-nine papers from the recent decade were selected here, in all of them Prof. Rybakowski is the first or the last author. The editorial in Neuropsychobiology on the 60th anniversary of lithium entering modern psychiatry is followed by the 2010 update on lithium in neuropsychiatry. The studies of an association between lithium efficacy and temperament as well as candidate genes are presented. The effects of lithium on cognitive, kidney, and thyroid functions were covered in many articles. The studies on lithium's biochemical mechanism with very small embryonic-like stem cells and mRNA of neuronal and glial markers are shown. Ultra-long-term therapy with lithium is described in five patients receiving lithium for more than 40 years, and in another paper, presenting a patient on lithium for half a century. Given the clinical and biological properties of lithium, this drug is presently greatly underutilized and efforts should be undertaken for challenging lithium's skepticism and optimizing its long-term administration. Such a message was expressed in a special paper published in 2018 and in several "state of the art" papers on lithium in 2020. About the Author: Prof. Janusz K. Rybakowski was the Head, Department of Adult Psychiatry, Poznan University of Medical Sciences, 1995-2016, the Chairman, Department of Psychiatry, Medical Academy, Bydgoszcz, 1985-1995, the NIH Fogarty Research Fellow, University of Pennsylvania, Philadelphia, 1976-1977. He was the President of the Polish Psychiatric Association, 1998-2001. Authored over 700 scientific articles, Hirsch Index 56, and the books "The Faces of Manic-Depressive Illness" (2009) and "Lithium - the Amazing Drug in Psychiatry" (2020). A member of the Editorial Board of 16 international journals. In 2012, received the Lifetime Achievement Award of the European Bipolar Forum, in 2015, the Lifetime Achievement Award in Biological Psychiatry of the World Federation of the Societies of Biological Psychiatry, and 2018, the Mogens Schou scientific award of the International Society of Bipolar Disorders.
Book Synopsis Psychopharmacology of Lithium by : Frederick Neil Johnson
Download or read book Psychopharmacology of Lithium written by Frederick Neil Johnson and published by Springer. This book was released on 2016-01-19 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis History of the Introduction of Lithium Into Medicine and Psychiatry by : Johan Schioldann
Download or read book History of the Introduction of Lithium Into Medicine and Psychiatry written by Johan Schioldann and published by . This book was released on 2009-01 with total page 363 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book traces the history of lithium therapy back to the 1800s. It contests the notion that the Australian man John Cade, who pioneered lithium therapy in Australia in the 1940s, was the first man to use the therapy. Tracing the history of lithium therapy, and evaluating Cade's research and potential breadth of reading and resources, the author comes to the conclusion that Cade was aware of previous writings on the topic but never acknowledged it. Cade has therefore become known as the 'pioneer' of this therapy, incorrectly.
Book Synopsis Lithium: A Doctor, a Drug, and a Breakthrough by : Walter A. Brown
Download or read book Lithium: A Doctor, a Drug, and a Breakthrough written by Walter A. Brown and published by Liveright Publishing. This book was released on 2019-08-13 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: The remarkable untold story of a miracle drug, the forgotten pioneer who discovered it, and the fight to bring lithium to the masses. The DNA double helix, penicillin, the X-ray, insulin—these are routinely cited as some of the most important medical discoveries of the twentieth century. And yet, the 1949 discovery of lithium as a cure for bipolar disorder is perhaps one of the most important—yet largely unsung—breakthroughs of the modern era. In Lithium, Walter Brown, a practicing psychiatrist and professor at Brown, reveals two unlikely success stories: that of John Cade, the physician whose discovery would come to save an untold number of lives and launch a pharmacological revolution, and that of a miraculous metal rescued from decades of stigmatization. From insulin comas and lobotomy to incarceration to exile, Brown chronicles the troubling history of the diagnosis and (often ineffective) treatment of bipolar disorder through the centuries, before the publication of a groundbreaking research paper in 1949. Cade’s “Lithium Salts in the Treatment of Psychotic Excitement” described, for the first time, lithium’s astonishing efficacy at both treating and preventing the recurrence of manic-depressive episodes, and would eventually transform the lives of patients, pharmaceutical researchers, and practicing physicians worldwide. And yet, as Brown shows, it would be decades before lithium would overcome widespread stigmatization as a dangerous substance, and the resistance from the pharmaceutical industry, which had little incentive to promote a naturally occurring drug that could not be patented. With a vivid portrait of the story’s unlikely hero, John Cade, Brown also describes a devoted naturalist who, unlike many modern medical researchers, did not benefit from prestigious research training or big funding sources (Cade’s “laboratory” was the unused pantry of an isolated mental hospital). As Brown shows, however, these humble conditions were the secret to his historic success: Cade was free to follow his own restless curiosity, rather than answer to an external funding source. As Lithium makes tragically clear, medical research—at least in America—has transformed in such a way that serendipitous discoveries like Cade’s are unlikely to occur ever again. Recently described by the New York Times as the “Cinderella” of psychiatric drugs, lithium has saved countless of lives and billions of dollars in healthcare costs. In this revelatory biography of a drug and the man who fought for its discovery, Brown crafts a captivating picture of modern medical history—revealing just how close we came to passing over this extraordinary cure.
Book Synopsis More Than 60 Years of Lithium in Contemporary Psychiatry by : Janusz K. Rybakowski
Download or read book More Than 60 Years of Lithium in Contemporary Psychiatry written by Janusz K. Rybakowski and published by . This book was released on 2010-06-03 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first remarkable results of the treatment of manic patients with lithium were published 60 years ago and to date lithium remains one of the most important psychotropic medications. In this special issue, research on clinical characteristics of persons prophylactically treated with lithium as well as the evolution of an outpatient setting providing long-term lithium therapy are presented. The most important clinical properties of lithium, such as prevention of affective recurrences, augmentation of antidepressants in treatment-resistant depression, and anti-aggressive and anti-suicidal effects are reviewed. Further, the neurobiology and pharmacogenetics of lithium are summarized and a report on the most recent international initiative aiming at performing a genome-wide association study in lithium-treated patients completes this issue. Psychiatrists, psychologists, and neurobiologists interested in optimal pharmacological treatment of patients with mood disorders and in the pathogenesis of such conditions will find up-to-date information in this special issue. Likewise it will be interesting reading for bipolar patients, their relatives and caregivers.
