Linear and Generalized Linear Mixed Models and Their Applications

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Publisher : Springer Science & Business Media
ISBN 13 : 0387479465
Total Pages : 257 pages
Book Rating : 4.3/5 (874 download)

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Book Synopsis Linear and Generalized Linear Mixed Models and Their Applications by : Jiming Jiang

Download or read book Linear and Generalized Linear Mixed Models and Their Applications written by Jiming Jiang and published by Springer Science & Business Media. This book was released on 2007-05-30 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers two major classes of mixed effects models, linear mixed models and generalized linear mixed models. It presents an up-to-date account of theory and methods in analysis of these models as well as their applications in various fields. The book offers a systematic approach to inference about non-Gaussian linear mixed models. Furthermore, it includes recently developed methods, such as mixed model diagnostics, mixed model selection, and jackknife method in the context of mixed models. The book is aimed at students, researchers and other practitioners who are interested in using mixed models for statistical data analysis.

Generalized Linear Mixed Models

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Publisher : CRC Press
ISBN 13 : 1439815135
Total Pages : 547 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Generalized Linear Mixed Models by : Walter W. Stroup

Download or read book Generalized Linear Mixed Models written by Walter W. Stroup and published by CRC Press. This book was released on 2016-04-19 with total page 547 pages. Available in PDF, EPUB and Kindle. Book excerpt: With numerous examples using SAS PROC GLIMMIX, this text presents an introduction to linear modeling using the generalized linear mixed model as an overarching conceptual framework. For readers new to linear models, the book helps them see the big picture. It shows how linear models fit with the rest of the core statistics curriculum and points out the major issues that statistical modelers must consider.

Analysis of Generalized Linear Mixed Models in the Agricultural and Natural Resources Sciences

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Publisher : John Wiley & Sons
ISBN 13 : 0891181822
Total Pages : 304 pages
Book Rating : 4.8/5 (911 download)

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Book Synopsis Analysis of Generalized Linear Mixed Models in the Agricultural and Natural Resources Sciences by : Edward E. Gbur

Download or read book Analysis of Generalized Linear Mixed Models in the Agricultural and Natural Resources Sciences written by Edward E. Gbur and published by John Wiley & Sons. This book was released on 2020-01-22 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Generalized Linear Mixed Models in the Agricultural and Natural Resources Sciences provides readers with an understanding and appreciation for the design and analysis of mixed models for non-normally distributed data. It is the only publication of its kind directed specifically toward the agricultural and natural resources sciences audience. Readers will especially benefit from the numerous worked examples based on actual experimental data and the discussion of pitfalls associated with incorrect analyses.

Generalized Linear Mixed Models

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Publisher : IMS
ISBN 13 : 9780940600546
Total Pages : 100 pages
Book Rating : 4.6/5 (5 download)

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Book Synopsis Generalized Linear Mixed Models by : Charles E. McCulloch

Download or read book Generalized Linear Mixed Models written by Charles E. McCulloch and published by IMS. This book was released on 2003 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt: Wiley Series in Probability and Statistics A modern perspective on mixed models The availability of powerful computing methods in recent decades has thrust linear and nonlinear mixed models into the mainstream of statistical application. This volume offers a modern perspective on generalized, linear, and mixed models, presenting a unified and accessible treatment of the newest statistical methods for analyzing correlated, nonnormally distributed data. As a follow-up to Searle's classic, Linear Models, and Variance Components by Searle, Casella, and McCulloch, this new work progresses from the basic one-way classification to generalized linear mixed models. A variety of statistical methods are explained and illustrated, with an emphasis on maximum likelihood and restricted maximum likelihood. An invaluable resource for applied statisticians and industrial practitioners, as well as students interested in the latest results, Generalized, Linear, and Mixed Models features: * A review of the basics of linear models and linear mixed models * Descriptions of models for nonnormal data, including generalized linear and nonlinear models * Analysis and illustration of techniques for a variety of real data sets * Information on the accommodation of longitudinal data using these models * Coverage of the prediction of realized values of random effects * A discussion of the impact of computing issues on mixed models

Generalized Linear Mixed Models

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Publisher : CRC Press
ISBN 13 : 1498755585
Total Pages : 671 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Generalized Linear Mixed Models by : Walter W. Stroup

Download or read book Generalized Linear Mixed Models written by Walter W. Stroup and published by CRC Press. This book was released on 2024-05-21 with total page 671 pages. Available in PDF, EPUB and Kindle. Book excerpt: Generalized Linear Mixed Models: Modern Concepts, Methods, and Applications (2nd edition) presents an updated introduction to linear modeling using the generalized linear mixed model (GLMM) as the overarching conceptual framework. For students new to statistical modeling, this book helps them see the big picture – linear modeling as broadly understood and its intimate connection with statistical design and mathematical statistics. For readers experienced in statistical practice, but new to GLMMs, the book provides a comprehensive introduction to GLMM methodology and its underlying theory. Unlike textbooks that focus on classical linear models or generalized linear models or mixed models, this book covers all of the above as members of a unified GLMM family of linear models. In addition to essential theory and methodology, this book features a rich collection of examples using SAS® software to illustrate GLMM practice. This second edition is updated to reflect lessons learned and experience gained regarding best practices and modeling choices faced by GLMM practitioners. New to this edition are two chapters focusing on Bayesian methods for GLMMs. Key Features: • Most statistical modeling books cover classical linear models or advanced generalized and mixed models; this book covers all members of the GLMM family – classical and advanced models. • Incorporates lessons learned from experience and on-going research to provide up-to-date examples of best practices. • Illustrates connections between statistical design and modeling: guidelines for translating study design into appropriate model and in-depth illustrations of how to implement these guidelines; use of GLMM methods to improve planning and design. • Discusses the difference between marginal and conditional models, differences in the inference space they are intended to address and when each type of model is appropriate. • In addition to likelihood-based frequentist estimation and inference, provides a brief introduction to Bayesian methods for GLMMs. Walt Stroup is an Emeritus Professor of Statistics. He served on the University of Nebraska statistics faculty for over 40 years, specializing in statistical modeling and statistical design. He is a Fellow of the American Statistical Association, winner of the University of Nebraska Outstanding Teaching and Innovative Curriculum Award and author or co-author of three books on mixed models and their extensions. Marina Ptukhina (Pa-too-he-nuh), PhD, is an Associate Professor of Statistics at Whitman College. She is interested in statistical modeling, design and analysis of research studies and their applications. Her research includes applications of statistics to economics, biostatistics and statistical education. Ptukhina earned a PhD in Statistics from the University of Nebraska-Lincoln, a Master of Science degree in Mathematics from Texas Tech University and a Specialist degree in Management from The National Technical University "Kharkiv Polytechnic Institute." Julie Garai, PhD, is a Data Scientist at Loop. She earned her PhD in Statistics from the University of Nebraska-Lincoln and a bachelor’s degree in Mathematics and Spanish from Doane College. Dr Garai actively collaborates with statisticians, psychologists, ecologists, forest scientists, software engineers, and business leaders in academia and industry. In her spare time, she enjoys leisurely walks with her dogs, dance parties with her children, and playing the trombone.

Mixed Models

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Publisher : John Wiley & Sons
ISBN 13 : 1118091574
Total Pages : 768 pages
Book Rating : 4.1/5 (18 download)

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Book Synopsis Mixed Models by : Eugene Demidenko

Download or read book Mixed Models written by Eugene Demidenko and published by John Wiley & Sons. This book was released on 2013-08-05 with total page 768 pages. Available in PDF, EPUB and Kindle. Book excerpt: Praise for the First Edition “This book will serve to greatly complement the growing number of texts dealing with mixed models, and I highly recommend including it in one’s personal library.” —Journal of the American Statistical Association Mixed modeling is a crucial area of statistics, enabling the analysis of clustered and longitudinal data. Mixed Models: Theory and Applications with R, Second Edition fills a gap in existing literature between mathematical and applied statistical books by presenting a powerful examination of mixed model theory and application with special attention given to the implementation in R. The new edition provides in-depth mathematical coverage of mixed models’ statistical properties and numerical algorithms, as well as nontraditional applications, such as regrowth curves, shapes, and images. The book features the latest topics in statistics including modeling of complex clustered or longitudinal data, modeling data with multiple sources of variation, modeling biological variety and heterogeneity, Healthy Akaike Information Criterion (HAIC), parameter multidimensionality, and statistics of image processing. Mixed Models: Theory and Applications with R, Second Edition features unique applications of mixed model methodology, as well as: Comprehensive theoretical discussions illustrated by examples and figures Over 300 exercises, end-of-section problems, updated data sets, and R subroutines Problems and extended projects requiring simulations in R intended to reinforce material Summaries of major results and general points of discussion at the end of each chapter Open problems in mixed modeling methodology, which can be used as the basis for research or PhD dissertations Ideal for graduate-level courses in mixed statistical modeling, the book is also an excellent reference for professionals in a range of fields, including cancer research, computer science, and engineering.

Generalized Linear Models

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Publisher : John Wiley & Sons
ISBN 13 : 0470556978
Total Pages : 521 pages
Book Rating : 4.4/5 (75 download)

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Book Synopsis Generalized Linear Models by : Raymond H. Myers

Download or read book Generalized Linear Models written by Raymond H. Myers and published by John Wiley & Sons. This book was released on 2012-01-20 with total page 521 pages. Available in PDF, EPUB and Kindle. Book excerpt: Praise for the First Edition "The obvious enthusiasm of Myers, Montgomery, and Vining and their reliance on their many examples as a major focus of their pedagogy make Generalized Linear Models a joy to read. Every statistician working in any area of applied science should buy it and experience the excitement of these new approaches to familiar activities." —Technometrics Generalized Linear Models: With Applications in Engineering and the Sciences, Second Edition continues to provide a clear introduction to the theoretical foundations and key applications of generalized linear models (GLMs). Maintaining the same nontechnical approach as its predecessor, this update has been thoroughly extended to include the latest developments, relevant computational approaches, and modern examples from the fields of engineering and physical sciences. This new edition maintains its accessible approach to the topic by reviewing the various types of problems that support the use of GLMs and providing an overview of the basic, related concepts such as multiple linear regression, nonlinear regression, least squares, and the maximum likelihood estimation procedure. Incorporating the latest developments, new features of this Second Edition include: A new chapter on random effects and designs for GLMs A thoroughly revised chapter on logistic and Poisson regression, now with additional results on goodness of fit testing, nominal and ordinal responses, and overdispersion A new emphasis on GLM design, with added sections on designs for regression models and optimal designs for nonlinear regression models Expanded discussion of weighted least squares, including examples that illustrate how to estimate the weights Illustrations of R code to perform GLM analysis The authors demonstrate the diverse applications of GLMs through numerous examples, from classical applications in the fields of biology and biopharmaceuticals to more modern examples related to engineering and quality assurance. The Second Edition has been designed to demonstrate the growing computational nature of GLMs, as SAS®, Minitab®, JMP®, and R software packages are used throughout the book to demonstrate fitting and analysis of generalized linear models, perform inference, and conduct diagnostic checking. Numerous figures and screen shots illustrating computer output are provided, and a related FTP site houses supplementary material, including computer commands and additional data sets. Generalized Linear Models, Second Edition is an excellent book for courses on regression analysis and regression modeling at the upper-undergraduate and graduate level. It also serves as a valuable reference for engineers, scientists, and statisticians who must understand and apply GLMs in their work.

Foundations of Linear and Generalized Linear Models

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Publisher : John Wiley & Sons
ISBN 13 : 1118730038
Total Pages : 471 pages
Book Rating : 4.1/5 (187 download)

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Book Synopsis Foundations of Linear and Generalized Linear Models by : Alan Agresti

Download or read book Foundations of Linear and Generalized Linear Models written by Alan Agresti and published by John Wiley & Sons. This book was released on 2015-02-23 with total page 471 pages. Available in PDF, EPUB and Kindle. Book excerpt: A valuable overview of the most important ideas and results in statistical modeling Written by a highly-experienced author, Foundations of Linear and Generalized Linear Models is a clear and comprehensive guide to the key concepts and results of linearstatistical models. The book presents a broad, in-depth overview of the most commonly usedstatistical models by discussing the theory underlying the models, R software applications,and examples with crafted models to elucidate key ideas and promote practical modelbuilding. The book begins by illustrating the fundamentals of linear models, such as how the model-fitting projects the data onto a model vector subspace and how orthogonal decompositions of the data yield information about the effects of explanatory variables. Subsequently, the book covers the most popular generalized linear models, which include binomial and multinomial logistic regression for categorical data, and Poisson and negative binomial loglinear models for count data. Focusing on the theoretical underpinnings of these models, Foundations ofLinear and Generalized Linear Models also features: An introduction to quasi-likelihood methods that require weaker distributional assumptions, such as generalized estimating equation methods An overview of linear mixed models and generalized linear mixed models with random effects for clustered correlated data, Bayesian modeling, and extensions to handle problematic cases such as high dimensional problems Numerous examples that use R software for all text data analyses More than 400 exercises for readers to practice and extend the theory, methods, and data analysis A supplementary website with datasets for the examples and exercises An invaluable textbook for upper-undergraduate and graduate-level students in statistics and biostatistics courses, Foundations of Linear and Generalized Linear Models is also an excellent reference for practicing statisticians and biostatisticians, as well as anyone who is interested in learning about the most important statistical models for analyzing data.

Interaction Effects in Linear and Generalized Linear Models

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Publisher : SAGE Publications
ISBN 13 : 1506365361
Total Pages : 427 pages
Book Rating : 4.5/5 (63 download)

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Book Synopsis Interaction Effects in Linear and Generalized Linear Models by : Robert L. Kaufman

Download or read book Interaction Effects in Linear and Generalized Linear Models written by Robert L. Kaufman and published by SAGE Publications. This book was released on 2018-09-06 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book is remarkable in its accessible treatment of interaction effects. Although this concept can be challenging for students (even those with some background in statistics), this book presents the material in a very accessible manner, with plenty of examples to help the reader understand how to interpret their results." –Nicole Kalaf-Hughes, Bowling Green State University Offering a clear set of workable examples with data and explanations, Interaction Effects in Linear and Generalized Linear Models is a comprehensive and accessible text that provides a unified approach to interpreting interaction effects. The book develops the statistical basis for the general principles of interpretive tools and applies them to a variety of examples, introduces the ICALC Toolkit for Stata, and offers a series of start-to-finish application examples to show students how to interpret interaction effects for a variety of different techniques of analysis, beginning with OLS regression. The author’s website provides a downloadable toolkit of Stata® routines to produce the calculations, tables, and graphics for each interpretive tool discussed. Also available are the Stata® dataset files to run the examples in the book.

Linear Models with R

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Publisher : CRC Press
ISBN 13 : 1439887349
Total Pages : 284 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Linear Models with R by : Julian J. Faraway

Download or read book Linear Models with R written by Julian J. Faraway and published by CRC Press. This book was released on 2016-04-19 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Hands-On Way to Learning Data AnalysisPart of the core of statistics, linear models are used to make predictions and explain the relationship between the response and the predictors. Understanding linear models is crucial to a broader competence in the practice of statistics. Linear Models with R, Second Edition explains how to use linear models

Linear Mixed Models

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Publisher : CRC Press
ISBN 13 : 1466560991
Total Pages : 442 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Linear Mixed Models by : Brady T. West

Download or read book Linear Mixed Models written by Brady T. West and published by CRC Press. This book was released on 2014-07-17 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: Highly recommended by JASA, Technometrics, and other journals, the first edition of this bestseller showed how to easily perform complex linear mixed model (LMM) analyses via a variety of software programs. Linear Mixed Models: A Practical Guide Using Statistical Software, Second Edition continues to lead readers step by step through the process of fitting LMMs. This second edition covers additional topics on the application of LMMs that are valuable for data analysts in all fields. It also updates the case studies using the latest versions of the software procedures and provides up-to-date information on the options and features of the software procedures available for fitting LMMs in SAS, SPSS, Stata, R/S-plus, and HLM. New to the Second Edition A new chapter on models with crossed random effects that uses a case study to illustrate software procedures capable of fitting these models Power analysis methods for longitudinal and clustered study designs, including software options for power analyses and suggested approaches to writing simulations Use of the lmer() function in the lme4 R package New sections on fitting LMMs to complex sample survey data and Bayesian approaches to making inferences based on LMMs Updated graphical procedures in the software packages Substantially revised index to enable more efficient reading and easier location of material on selected topics or software options More practical recommendations on using the software for analysis A new R package (WWGbook) that contains all of the data sets used in the examples Ideal for anyone who uses software for statistical modeling, this book eliminates the need to read multiple software-specific texts by covering the most popular software programs for fitting LMMs in one handy guide. The authors illustrate the models and methods through real-world examples that enable comparisons of model-fitting options and results across the software procedures.

Linear Mixed Models

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Publisher : CRC Press
ISBN 13 : 1420010433
Total Pages : 376 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Linear Mixed Models by : Brady T. West

Download or read book Linear Mixed Models written by Brady T. West and published by CRC Press. This book was released on 2006-11-22 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Simplifying the often confusing array of software programs for fitting linear mixed models (LMMs), Linear Mixed Models: A Practical Guide Using Statistical Software provides a basic introduction to primary concepts, notation, software implementation, model interpretation, and visualization of clustered and longitudinal data. This easy-to-nav

Linear Models

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Publisher : John Wiley & Sons
ISBN 13 : 9780470377970
Total Pages : 288 pages
Book Rating : 4.3/5 (779 download)

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Book Synopsis Linear Models by : Brenton R. Clarke

Download or read book Linear Models written by Brenton R. Clarke and published by John Wiley & Sons. This book was released on 2008-09-19 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: An insightful approach to the analysis of variance in the study of linear models Linear Models explores the theory of linear models and the dynamic relationships that these models have with Analysis of Variance (ANOVA), experimental design, and random and mixed-model effects. This one-of-a-kind book emphasizes an approach that clearly explains the distribution theory of linear models and experimental design starting from basic mathematical concepts in linear algebra. The author begins with a presentation of the classic fixed-effects linear model and goes on to illustrate eight common linear models, along with the value of their use in statistics. From this foundation, subsequent chapters introduce concepts pertaining to the linear model, starting with vector space theory and the theory of least-squares estimation. An outline of the Helmert matrix is also presented, along with a thorough explanation of how the ANOVA is created in both typical two-way and higher layout designs, ultimately revealing the distribution theory. Other important topics covered include: Vector space theory The theory of least squares estimation Gauss-Markov theorem Kronecker products Diagnostic and robust methods for linear models Likelihood approaches to estimation A discussion of Bayesian theory is also included for purposes of comparison and contrast, and numerous illustrative exercises assist the reader with uncovering the nature of the models, using both classic and new data sets. Requiring only a working knowledge of basic probability and statistical inference, Linear Models is a valuable book for courses on linear models at the upper-undergraduate and graduate levels. It is also an excellent reference for practitioners who use linear models to conduct research in the fields of econometrics, psychology, sociology, biology, and agriculture.

Multivariate Generalized Linear Mixed Models Using R

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Publisher : CRC Press
ISBN 13 : 1439813264
Total Pages : 306 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Multivariate Generalized Linear Mixed Models Using R by : Damon Mark Berridge

Download or read book Multivariate Generalized Linear Mixed Models Using R written by Damon Mark Berridge and published by CRC Press. This book was released on 2011-04-25 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multivariate Generalized Linear Mixed Models Using R presents robust and methodologically sound models for analyzing large and complex data sets, enabling readers to answer increasingly complex research questions. The book applies the principles of modeling to longitudinal data from panel and related studies via the Sabre software package in R. A Unified Framework for a Broad Class of Models The authors first discuss members of the family of generalized linear models, gradually adding complexity to the modeling framework by incorporating random effects. After reviewing the generalized linear model notation, they illustrate a range of random effects models, including three-level, multivariate, endpoint, event history, and state dependence models. They estimate the multivariate generalized linear mixed models (MGLMMs) using either standard or adaptive Gaussian quadrature. The authors also compare two-level fixed and random effects linear models. The appendices contain additional information on quadrature, model estimation, and endogenous variables, along with SabreR commands and examples. Improve Your Longitudinal Study In medical and social science research, MGLMMs help disentangle state dependence from incidental parameters. Focusing on these sophisticated data analysis techniques, this book explains the statistical theory and modeling involved in longitudinal studies. Many examples throughout the text illustrate the analysis of real-world data sets. Exercises, solutions, and other material are available on a supporting website.

Generalized Linear Models

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Publisher : Routledge
ISBN 13 : 1351445847
Total Pages : 361 pages
Book Rating : 4.3/5 (514 download)

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Book Synopsis Generalized Linear Models by : P. McCullagh

Download or read book Generalized Linear Models written by P. McCullagh and published by Routledge. This book was released on 2019-01-22 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: The success of the first edition of Generalized Linear Models led to the updated Second Edition, which continues to provide a definitive unified, treatment of methods for the analysis of diverse types of data. Today, it remains popular for its clarity, richness of content and direct relevance to agricultural, biological, health, engineering, and ot

Linear Mixed-Effects Models Using R

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Publisher : Springer Science & Business Media
ISBN 13 : 1461439000
Total Pages : 558 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Linear Mixed-Effects Models Using R by : Andrzej Gałecki

Download or read book Linear Mixed-Effects Models Using R written by Andrzej Gałecki and published by Springer Science & Business Media. This book was released on 2013-02-05 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt: Linear mixed-effects models (LMMs) are an important class of statistical models that can be used to analyze correlated data. Such data are encountered in a variety of fields including biostatistics, public health, psychometrics, educational measurement, and sociology. This book aims to support a wide range of uses for the models by applied researchers in those and other fields by providing state-of-the-art descriptions of the implementation of LMMs in R. To help readers to get familiar with the features of the models and the details of carrying them out in R, the book includes a review of the most important theoretical concepts of the models. The presentation connects theory, software and applications. It is built up incrementally, starting with a summary of the concepts underlying simpler classes of linear models like the classical regression model, and carrying them forward to LMMs. A similar step-by-step approach is used to describe the R tools for LMMs. All the classes of linear models presented in the book are illustrated using real-life data. The book also introduces several novel R tools for LMMs, including new class of variance-covariance structure for random-effects, methods for influence diagnostics and for power calculations. They are included into an R package that should assist the readers in applying these and other methods presented in this text.

Mixed Effects Models for Complex Data

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Publisher : CRC Press
ISBN 13 : 9781420074086
Total Pages : 431 pages
Book Rating : 4.0/5 (74 download)

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Book Synopsis Mixed Effects Models for Complex Data by : Lang Wu

Download or read book Mixed Effects Models for Complex Data written by Lang Wu and published by CRC Press. This book was released on 2009-11-11 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although standard mixed effects models are useful in a range of studies, other approaches must often be used in correlation with them when studying complex or incomplete data. Mixed Effects Models for Complex Data discusses commonly used mixed effects models and presents appropriate approaches to address dropouts, missing data, measurement errors, censoring, and outliers. For each class of mixed effects model, the author reviews the corresponding class of regression model for cross-sectional data. An overview of general models and methods, along with motivating examples After presenting real data examples and outlining general approaches to the analysis of longitudinal/clustered data and incomplete data, the book introduces linear mixed effects (LME) models, generalized linear mixed models (GLMMs), nonlinear mixed effects (NLME) models, and semiparametric and nonparametric mixed effects models. It also includes general approaches for the analysis of complex data with missing values, measurement errors, censoring, and outliers. Self-contained coverage of specific topics Subsequent chapters delve more deeply into missing data problems, covariate measurement errors, and censored responses in mixed effects models. Focusing on incomplete data, the book also covers survival and frailty models, joint models of survival and longitudinal data, robust methods for mixed effects models, marginal generalized estimating equation (GEE) models for longitudinal or clustered data, and Bayesian methods for mixed effects models. Background material In the appendix, the author provides background information, such as likelihood theory, the Gibbs sampler, rejection and importance sampling methods, numerical integration methods, optimization methods, bootstrap, and matrix algebra. Failure to properly address missing data, measurement errors, and other issues in statistical analyses can lead to severely biased or misleading results. This book explores the biases that arise when naïve methods are used and shows which approaches should be used to achieve accurate results in longitudinal data analysis.