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Life From An Rna World
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Book Synopsis Life from an RNA World by : Michael Yarus
Download or read book Life from an RNA World written by Michael Yarus and published by Harvard University Press. This book was released on 2010 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: A majority of evolutionary biologists believe that we now can envision our biological predecessors--not the first, but nearly the first, living beings on Earth. This book is about these vanished forebears. The era between the first rudimentary life on Earth and the appearance of more complex beings is called the RNA world. It is RNA (ribonucleic acid) long believed to be a mere biologic copier and messenger, that offers a glimpse into our ancient predecessors. To describe early RNA creatures, here called "ribocytes" or RNA cells, the author uses basics of molecular biology. He reviews our current understanding of the tree of life, examines the structure of RNA itself, explains the operation of the genetic code, and more. Courting controversy among those who question the role of ribocytes -- citing the chemical fragility of RNA and the uncertainty about the origin of an RNA synthetic apparatus -- he offers a vision of early life on Earth.
Book Synopsis RNA Worlds: New Tools for Deep Exploration by : Thomas R. Cech
Download or read book RNA Worlds: New Tools for Deep Exploration written by Thomas R. Cech and published by . This book was released on 2018-12-31 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: "A Subject Collection from Cold Spring Harbor Perspectives in Biology."
Book Synopsis The RNA World by : Raymond F. Gesteland
Download or read book The RNA World written by Raymond F. Gesteland and published by . This book was released on 1999 with total page 744 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Opening Doors: Joan Steitz and Jennifer Doudna of the RNA World by : Laura L Mays Hoopes
Download or read book Opening Doors: Joan Steitz and Jennifer Doudna of the RNA World written by Laura L Mays Hoopes and published by Lulu.com. This book was released on 2019-03-08 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: A dual biography of Joan Steitz and Jennifer Doudna, two women who combined successful home lives with successful careers in science.
Download or read book RNA Worlds written by John F. Atkins and published by . This book was released on 2011 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume reviews our understanding of two RNA worlds: the primordial RNA world before DNA, in which RNA was both information store and biocatalyst; and the contemporary RNA world, in which mRNA, tRNA, rRNA, siRNA, miRNA, and a host of other RNAs operate.
Book Synopsis Life's Greatest Secret by : Matthew Cobb
Download or read book Life's Greatest Secret written by Matthew Cobb and published by Basic Books. This book was released on 2015-07-07 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Everyone has heard of the story of DNA as the story of Watson and Crick and Rosalind Franklin, but knowing the structure of DNA was only a part of a greater struggle to understand life’s secrets. Life’s Greatest Secret is the story of the discovery and cracking of the genetic code, the thing that ultimately enables a spiraling molecule to give rise to the life that exists all around us. This great scientific breakthrough has had farreaching consequences for how we understand ourselves and our place in the natural world, and for how we might take control of our (and life’s) future. Life’s Greatest Secret mixes remarkable insights, theoretical dead-ends, and ingenious experiments with the swift pace of a thriller. From New York to Paris, Cambridge, Massachusetts, to Cambridge, England, and London to Moscow, the greatest discovery of twentieth-century biology was truly a global feat. Biologist and historian of science Matthew Cobb gives the full and rich account of the cooperation and competition between the eccentric characters—mathematicians, physicists, information theorists, and biologists—who contributed to this revolutionary new science. And, while every new discovery was a leap forward for science, Cobb shows how every new answer inevitably led to new questions that were at least as difficult to answer: just ask anyone who had hoped that the successful completion of the Human Genome Project was going to truly yield the book of life, or that a better understanding of epigenetics or “junk DNA” was going to be the final piece of the puzzle. But the setbacks and unexpected discoveries are what make the science exciting, and it is Matthew Cobb’s telling that makes them worth reading. This is a riveting story of humans exploring what it is that makes us human and how the world works, and it is essential reading for anyone who’d like to explore those questions for themselves.
Download or read book RNA written by James E. Darnell and published by . This book was released on 2011 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: RNA molecules could function as catalysts. --
Book Synopsis Molecular Biology of RNA by : David Elliott
Download or read book Molecular Biology of RNA written by David Elliott and published by Oxford University Press. This book was released on 2017-01-31 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: RNA plays a central, and until recently, somewhat underestimated role in the genetics underlying all forms of life on earth. This versatile molecule not only plays a crucial part in the synthesis of proteins from a DNA template, but is also intrinsically involved in the regulation of gene expression, and can even act as a catalyst in the form of a ribozyme. This latter property has led to the hypothesis that RNA - rather than DNA - could have played an essential part in the origin of life itself. This landmark text provides a systematic overview of the exciting and rapidly moving field of RNA biology. Key pioneering experiments, which provided the underlying evidence for what we now know, are described throughout, while the relevance of the subject to human disease is highlighted via frequent boxes. For the second edition of Molecular Biology of RNA, more introductory material has been incorporated at the beginning of the text, to aid students studying the subject for the first time. Throughout the text, new material has been included - particularly in relation to RNA binding domains, non-coding RNAs, and the connection between RNA biology and epigenetics. Finally, a new closing chapter discusses how exciting new technologies are being used to explore current topical areas of research.
Book Synopsis The Origin of Life on the Earth by : A. I. Oparin
Download or read book The Origin of Life on the Earth written by A. I. Oparin and published by Elsevier. This book was released on 2013-09-03 with total page 708 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Origin of Life on the Earth covers the proceedings of the First International Symposium of The Origin of Life on the Earth, held at Moscow on August 19-24, 1957. This symposium brings together numerous scientific studies on the evolutionary principles and the different stages in the evolutionary development of matter. This book is organized into seven parts encompassing 60 chapters. The first parts discuss evidence that on the formation of hydrocarbons and their derivatives on the surface of the Earth even before the emergence of life. The subsequent parts are devoted to the many asymmetrical syntheses under the influence of circularly-polarized ultraviolet light, by catalytic reactions occurring on the surface of quartz crystals, and spontaneously by slow crystallization from solutions. These topics are followed by reviews on the possible means of abiogenic formation of amino acids, porphyrins, protein-like polymers, polynucleotides and other high-molecular organic compounds. Considerable chapters explore the complete possibility of the primary formation of these compounds on the surface of the Earth even before life was present on it. Other general topics covered include nucleic acids, nucleoproteins and viruses. The last part considers general biochemical problems connected with the further development of metabolism. This book will be of value to astronomers, physicists, geologists, chemists, and biologists.
Book Synopsis The First Cell by : Ulrich C. Schreiber
Download or read book The First Cell written by Ulrich C. Schreiber and published by Springer Nature. This book was released on 2020-06-05 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduces a fresh perspective on the conditions for the genesis of the first cell. An important possible environment of the prehistoric Earth has long been overlooked as a host to the perfect biochemical conditions for this process. The first complexes of continental crust on the early Earth must have already contained systems of interconnected cracks and cavities, which were filled with volatiles like water, carbon dioxide and nitrogen. This book offers insights into how these conditions may have provided the ideal physical and chemical setting for the formation of protocells and early stages of life. The authors support their hypothesis with a number of astonishing findings from laboratory experiments focusing on a variety of organic compounds, and on the formation of key cellular ingredients and of primitive cell-like structures. Moreover, they discuss the principles of prebiotic evolution regarding the aspects of order and complexity. Guiding readers through various stages of hypotheses and re-created evolutionary processes, the book is enriched with personal remarks and experiences throughout, reflecting the authors' personal quest to solve the mystery surrounding the first cell.
Book Synopsis The Emergence of Life on Earth by : Iris Fry
Download or read book The Emergence of Life on Earth written by Iris Fry and published by Rutgers University Press. This book was released on 2000 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: How did life emerge on Earth? Is there life on other worlds? These questions, until recently confined to the pages of speculative essays and tabloid headlines, are now the subject of legitimate scientific research. This book presents a unique perspective--a combined historical, scientific, and philosophical analysis, which does justice to the complex nature of the subject. The book's first part offers an overview of the main ideas on the origin of life as they developed from antiquity until the twentieth century. The second, more detailed part of the book examines contemporary theories and major debates within the origin-of-life scientific community. Topics include: Aristotle and the Greek atomists' conceptions of the organism Alexander Oparin and J.B.S. Haldane's 1920s breakthrough papers Possible life on Mars?
Book Synopsis RNA-Based Regulation in Human Health and Disease by :
Download or read book RNA-Based Regulation in Human Health and Disease written by and published by Academic Press. This book was released on 2020-08-19 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: RNA-based Regulation in Human Health and Disease offers an in-depth exploration of RNA mediated genome regulation at different hierarchies. Beginning with multitude of canonical and non-canonical RNA populations, especially noncoding RNA in human physiology and evolution, further sections examine the various classes of RNAs (from small to large noncoding and extracellular RNAs), functional categories of RNA regulation (RNA-binding proteins, alternative splicing, RNA editing, antisense transcripts and RNA G-quadruplexes), dynamic aspects of RNA regulation modulating physiological homeostasis (aging), role of RNA beyond humans, tools and technologies for RNA research (wet lab and computational) and future prospects for RNA-based diagnostics and therapeutics. One of the core strengths of the book includes spectrum of disease-specific chapters from experts in the field highlighting RNA-based regulation in metabolic & neurodegenerative disorders, cancer, inflammatory disease, viral and bacterial infections. We hope the book helps researchers, students and clinicians appreciate the role of RNA-based regulation in genome regulation, aiding the development of useful biomarkers for prognosis, diagnosis, and novel RNA-based therapeutics. Comprehensive information of non-canonical RNA-based genome regulation modulating human health and disease Defines RNA classes with special emphasis on unexplored world of noncoding RNA at different hierarchies Disease specific role of RNA - causal, prognostic, diagnostic and therapeutic Features contributions from leading experts in the field
Book Synopsis The Origins of Life by : D. W. Deamer
Download or read book The Origins of Life written by D. W. Deamer and published by Cold Spring Harbor Perspective. This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Life arose on Earth more than three billion years ago. How the first self-replicating systems emerged from prebiotic chemistry and evolved into primitive cell-like entities is an area of intense research, spanning molecular and cellular biology, organic chemistry, cosmology, geology, and atmospheric science. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology provides a comprehensive account of the environment of the early Earth and the mechanisms by which the organic molecules present may have self-assembled to form replicating material such as RNA and other polymers. The contributors examine the energetic requirements for this process and focus in particular on the essential role of semi-permeable compartments in containment of primitive genetic systems. Also covered in the book are new synthetic approaches for fabricating cellular systems, the potentially extraterrestrial origin of life's building blocks, and the possibility that life once existed on Mars. Comprising five sections Setting the Stage, Components of First Life, Primitive Systems, First Polymers, and Transition to a Microbial World it is a vital reference for all scientists interested in the origin of life on Earth and the likelihood that it has arisen on other planets
Book Synopsis The Limits of Organic Life in Planetary Systems by : National Research Council
Download or read book The Limits of Organic Life in Planetary Systems written by National Research Council and published by National Academies Press. This book was released on 2007-07-26 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: The search for life in the solar system and beyond has to date been governed by a model based on what we know about life on Earth (terran life). Most of NASA's mission planning is focused on locations where liquid water is possible and emphasizes searches for structures that resemble cells in terran organisms. It is possible, however, that life exists that is based on chemical reactions that do not involve carbon compounds, that occurs in solvents other than water, or that involves oxidation-reduction reactions without oxygen gas. To assist NASA incorporate this possibility in its efforts to search for life, the NRC was asked to carry out a study to evaluate whether nonstandard biochemistry might support life in solar system and conceivable extrasolar environments, and to define areas to guide research in this area. This book presents an exploration of a limited set of hypothetical chemistries of life, a review of current knowledge concerning key questions or hypotheses about nonterran life, and suggestions for future research.
Download or read book Astrobiology written by Akihiko Yamagishi and published by Springer. This book was released on 2019-02-27 with total page 465 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides concise and cutting-edge reviews in astrobiology, a young and still emerging multidisciplinary field of science that addresses the fundamental questions of how life originated and diversified on Earth, whether life exists beyond Earth, and what is the future for life on Earth. Readers will find coverage of the latest understanding of a wide range of fascinating topics, including, for example, solar system formation, the origins of life, the history of Earth as revealed by geology, the evolution of intelligence on Earth, the implications of genome data, insights from extremophile research, and the possible existence of life on other planets within and beyond the solar system. Each chapter contains a brief summary of the current status of the topic under discussion, sufficient references to enable more detailed study, and descriptions of recent findings and forthcoming missions or anticipated research. Written by leading experts in astronomy, planetary science, geoscience, chemistry, biology, and physics, this insightful and thought-provoking book will appeal to all students and scientists who are interested in life and space.
Book Synopsis The Emergence of Life by : Pier Luigi Luisi
Download or read book The Emergence of Life written by Pier Luigi Luisi and published by Cambridge University Press. This book was released on 2006-07-13 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: The origin of life from inanimate matter has been the focus of much research for decades, both experimentally and philosophically. Luisi takes the reader through the consecutive stages from prebiotic chemistry to synthetic biology, uniquely combining both approaches. This book presents a systematic course discussing the successive stages of self-organisation, emergence, self-replication, autopoiesis, synthetic compartments and construction of cellular models, in order to demonstrate the spontaneous increase in complexity from inanimate matter to the first cellular life forms. A chapter is dedicated to each of these steps, using a number of synthetic and biological examples. With end-of-chapter review questions to aid reader comprehension, this book will appeal to graduate students and academics researching the origin of life and related areas such as evolutionary biology, biochemistry, molecular biology, biophysics and natural sciences.
Book Synopsis The Selfish Gene by : Richard Dawkins
Download or read book The Selfish Gene written by Richard Dawkins and published by Oxford University Press, USA. This book was released on 1989 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Science need not be dull and bogged down by jargon, as Richard Dawkins proves in this entertaining look at evolution. The themes he takes up are the concepts of altruistic and selfish behaviour; the genetical definition of selfish interest; the evolution of aggressive behaviour; kinshiptheory; sex ratio theory; reciprocal altruism; deceit; and the natural selection of sex differences. 'Should be read, can be read by almost anyone. It describes with great skill a new face of the theory of evolution.' W.D. Hamilton, Science
