Lectures on Statistical Physics and Protein Folding

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Author :
Publisher : World Scientific
ISBN 13 : 9812561439
Total Pages : 159 pages
Book Rating : 4.8/5 (125 download)

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Book Synopsis Lectures on Statistical Physics and Protein Folding by : Kerson Huang

Download or read book Lectures on Statistical Physics and Protein Folding written by Kerson Huang and published by World Scientific. This book was released on 2005 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduces an approach to protein folding from the point of view of kinetic theory. There is an abundance of data on protein folding, but few proposals are available on the mechanism driving the process. Here, presented for the first time, are suggestion on possible research directions, as developed by the author in collaboration with C. C. Lin. The first half of this invaluable book contains a concise but relatively complete review of relevant topics in statistical mechanics and kinetic theory. It includes standard topics such as thermodynamics, the Maxwell-Boltzmann distribution, and ensemble theory. Special discussions include the dynamics of phase transitions, and Brownian motion as an illustration of stochastic processes. The second half develops topics in molecular biology and protein structure, with a view to discovering mechanisms underlying protein folding. Attention is focused on the energy flow through the protein in its folded state. A mathematical model, based on the Brownian motion of coupled harmonic oscillators, is worked out in the appendix.

Lectures on Statistical Physics and Protein Folding

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Author :
Publisher : World Scientific
ISBN 13 : 9812561439
Total Pages : 159 pages
Book Rating : 4.8/5 (125 download)

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Book Synopsis Lectures on Statistical Physics and Protein Folding by : Kerson Huang

Download or read book Lectures on Statistical Physics and Protein Folding written by Kerson Huang and published by World Scientific. This book was released on 2005 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduces an approach to protein folding from the point of view of kinetic theory. There is an abundance of data on protein folding, but few proposals are available on the mechanism driving the process. Here, presented for the first time, are suggestion on possible research directions, as developed by the author in collaboration with C. C. Lin. The first half of this invaluable book contains a concise but relatively complete review of relevant topics in statistical mechanics and kinetic theory. It includes standard topics such as thermodynamics, the Maxwell-Boltzmann distribution, and ensemble theory. Special discussions include the dynamics of phase transitions, and Brownian motion as an illustration of stochastic processes. The second half develops topics in molecular biology and protein structure, with a view to discovering mechanisms underlying protein folding. Attention is focused on the energy flow through the protein in its folded state. A mathematical model, based on the Brownian motion of coupled harmonic oscillators, is worked out in the appendix.

Protein Physics

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Publisher : Academic Press
ISBN 13 : 9780122567810
Total Pages : 382 pages
Book Rating : 4.5/5 (678 download)

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Book Synopsis Protein Physics by : Alexei V. Finkelstein

Download or read book Protein Physics written by Alexei V. Finkelstein and published by Academic Press. This book was released on 2002-05-14 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Covers the most general problems of protein structure, folding and function and introduces the concepts and theories. It deals with fibrous, membrane and especially water-soluble globular proteins, in both their native and denatured states. The book summarizes and presents in a systematic way the results of several decades of worldwide fundamental research on protein physics, structure and folding"--Back cover.

Statistical Physics of Protein Folding and Aggregation

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Publisher :
ISBN 13 : 9789162860738
Total Pages : 118 pages
Book Rating : 4.8/5 (67 download)

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Book Synopsis Statistical Physics of Protein Folding and Aggregation by : Giorgio Favrin

Download or read book Statistical Physics of Protein Folding and Aggregation written by Giorgio Favrin and published by . This book was released on 2004 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Statistical Mechanics, Protein Structure, and Protein Substrate Interactions

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Author :
Publisher : NATO Science Series B
ISBN 13 :
Total Pages : 424 pages
Book Rating : 4.X/5 (2 download)

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Book Synopsis Statistical Mechanics, Protein Structure, and Protein Substrate Interactions by : Sebastian Doniach

Download or read book Statistical Mechanics, Protein Structure, and Protein Substrate Interactions written by Sebastian Doniach and published by NATO Science Series B. This book was released on 1994-09-30 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of a NATO ARW held in Cargese, Corsica, France, June 1-5, 1993

Aspects of Physical Biology

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Publisher : Springer
ISBN 13 : 3540787658
Total Pages : 236 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Aspects of Physical Biology by : Giancarlo Franzese

Download or read book Aspects of Physical Biology written by Giancarlo Franzese and published by Springer. This book was released on 2008-12-02 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: The application to Biology of the methodologies developed in Physics is attracting an increasing interest from the scientific community. It has led to the emergence of a new interdisciplinary field, called Physical Biology, with the aim of reaching a better understanding of the biological mechanisms at molecular and cellular levels. Statistical Mechanics in particular plays an important role in the development of this new field. For this reason, the XXth session of the famous Sitges Conference on Statistical Physics was dedicated to "Physical Biology: from Molecular Interactions to Cellular Behavior". As is by now tradition, a number of lectures were subsequently selected, expanded and updated for publication as lecture notes, so as to provide both a state-of-the-art introduction and overview to a number of subjects of broader interest and to favor the interchange and cross-fertilization of ideas between biologists and physicists. The present volume focuses on three main subtopics (biological water, protein solutions as well as transport and replication), presenting for each of them the on-going debates on recent results. The role of water in biological processes, the mechanisms of protein folding, the phases and cooperative effects in biological solutions, the thermodynamic description of replication, transport and neural activity, all are subjects that are revised in this volume, based on new experiments and new theoretical interpretations.

Statistical Mechanics and Kinetics of Protein Folding and Aggregation

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Publisher :
ISBN 13 :
Total Pages : 316 pages
Book Rating : 4.:/5 (825 download)

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Book Synopsis Statistical Mechanics and Kinetics of Protein Folding and Aggregation by : John Stephen Schreck

Download or read book Statistical Mechanics and Kinetics of Protein Folding and Aggregation written by John Stephen Schreck and published by . This book was released on 2013 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advisor: Jian-Min Yuan.

Statistical Mechanics, Protein Structure, and Protein Substrate Interactions

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Publisher :
ISBN 13 : 9781489913500
Total Pages : 420 pages
Book Rating : 4.9/5 (135 download)

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Book Synopsis Statistical Mechanics, Protein Structure, and Protein Substrate Interactions by : Sebastian Doniach

Download or read book Statistical Mechanics, Protein Structure, and Protein Substrate Interactions written by Sebastian Doniach and published by . This book was released on 2014-09-01 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Software Tools and Algorithms for Biological Systems

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Publisher : Springer Science & Business Media
ISBN 13 : 1441970460
Total Pages : 776 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Software Tools and Algorithms for Biological Systems by : Hamid Arabnia

Download or read book Software Tools and Algorithms for Biological Systems written by Hamid Arabnia and published by Springer Science & Business Media. This book was released on 2011-03-23 with total page 776 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Software Tools and Algorithms for Biological Systems" is composed of a collection of papers received in response to an announcement that was widely distributed to academicians and practitioners in the broad area of computational biology and software tools. Also, selected authors of accepted papers of BIOCOMP’09 proceedings (International Conference on Bioinformatics and Computational Biology: July 13-16, 2009; Las Vegas, Nevada, USA) were invited to submit the extended versions of their papers for evaluation.

Sailing the Ocean of Complexity

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Publisher : Oxford University Press
ISBN 13 : 0192897896
Total Pages : 401 pages
Book Rating : 4.1/5 (928 download)

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Book Synopsis Sailing the Ocean of Complexity by : Sauro Succi

Download or read book Sailing the Ocean of Complexity written by Sauro Succi and published by Oxford University Press. This book was released on 2022 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Both superb and essential... Succi, with clarity and wit, takes us from quarks and Boltzmann to soft matter - precisely the frontier of physics and life." Stuart Kauffman, MacArthur Fellow, Fellow of the Royal Society of Canada, Gold Medal Accademia Lincea We live in a world of utmost complexity, outside and within us. There are thousand of billions of billions of stars out there in the Universe, a hundred times more molecules in a glass of water, and another hundred times more in our body, all working in sync to keep us alive and well. At face value, such numbers spell certain doom for our ability to make any sense at all of the world around and within us. And yet, they don't. Why, and how - this book endeavours to provide an answer to these questions with specific reference to a selected window of the physics-biology interface. The story unfolds over four main Parts. Part I provides an introduction to the main organizational principles which govern the functioning of complex systems in general, such as nonlinearity, nonlocality and ultra-dimensions. Part II deals with thermodynamics, the science of change, starting with its historical foundations laid down in the 19th century, and then moving on to its modern and still open developments in connection with biology and cosmology. Part III deals with the main character of this book, free energy, and the wondrous scenarios opened up by its merger with the modern tools of statistical physics. It also describes the basic facts about soft matter, the state of matter most relevant to biological organisms. Finally, Part IV discusses the connection between time and complexity, and its profound implications on the human condition, i.e. the one-sided nature of time and the awareness of human mortality. It concludes with a few personal considerations about the special place of emotions and humility in science.

Mathematical Modeling of Collective Behavior in Socio-Economic and Life Sciences

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Publisher : Springer Science & Business Media
ISBN 13 : 0817649468
Total Pages : 437 pages
Book Rating : 4.8/5 (176 download)

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Book Synopsis Mathematical Modeling of Collective Behavior in Socio-Economic and Life Sciences by : Giovanni Naldi

Download or read book Mathematical Modeling of Collective Behavior in Socio-Economic and Life Sciences written by Giovanni Naldi and published by Springer Science & Business Media. This book was released on 2010-08-12 with total page 437 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using examples from finance and modern warfare to the flocking of birds and the swarming of bacteria, the collected research in this volume demonstrates the common methodological approaches and tools for modeling and simulating collective behavior. The topics presented point toward new and challenging frontiers of applied mathematics, making the volume a useful reference text for applied mathematicians, physicists, biologists, and economists involved in the modeling of socio-economic systems.

Protein-Protein Interactions

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Publisher : BoD – Books on Demand
ISBN 13 : 9535103970
Total Pages : 488 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Protein-Protein Interactions by : Weibo Cai

Download or read book Protein-Protein Interactions written by Weibo Cai and published by BoD – Books on Demand. This book was released on 2012-03-30 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proteins are indispensable players in virtually all biological events. The functions of proteins are coordinated through intricate regulatory networks of transient protein-protein interactions (PPIs). To predict and/or study PPIs, a wide variety of techniques have been developed over the last several decades. Many in vitro and in vivo assays have been implemented to explore the mechanism of these ubiquitous interactions. However, despite significant advances in these experimental approaches, many limitations exist such as false-positives/false-negatives, difficulty in obtaining crystal structures of proteins, challenges in the detection of transient PPI, among others. To overcome these limitations, many computational approaches have been developed which are becoming increasingly widely used to facilitate the investigation of PPIs. This book has gathered an ensemble of experts in the field, in 22 chapters, which have been broadly categorized into Computational Approaches, Experimental Approaches, and Others.

Biomat 2007 - International Symposium On Mathematical And Computational Biology

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Author :
Publisher : World Scientific
ISBN 13 : 9814471291
Total Pages : 406 pages
Book Rating : 4.8/5 (144 download)

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Book Synopsis Biomat 2007 - International Symposium On Mathematical And Computational Biology by : Rubem P Mondaini

Download or read book Biomat 2007 - International Symposium On Mathematical And Computational Biology written by Rubem P Mondaini and published by World Scientific. This book was released on 2008-06-23 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present volume contains the contributions of the keynote speakers of the BIOMAT 2007 Symposium as well as selected contributed papers in the areas of mathematical biology, biological physics, biophysics and bioinformatics. It contains new results on some aspects of Lotka-Volterra equations, the proposal of using differential geometry to model neurosurgical tools, recent data on epidemiological modeling, pattern recognition and comprehensive reviews on the structure of proteins, the folding problem and the influence of Allee effects on population dynamics.This book contains some original results on the growth of gliomas: the role played by membrane channels on activity-dependent modulation of spike transmission; a proposal for reconsidering the concept of gene and the understanding of the mechanisms responsible for gene expression; a differential geometric approach to the influence of the drying effect on the dynamics of pods of Leguminosae; the comparison of agent-based models with the approach of differential equations on the study of selection mechanisms in germinal centers; and the synchronization phenomenon for protocell systems driven by linear kinetic equations.

BIOMAT 2007

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Publisher : World Scientific
ISBN 13 : 9812812326
Total Pages : 406 pages
Book Rating : 4.8/5 (128 download)

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Book Synopsis BIOMAT 2007 by : Rubem Mondaini

Download or read book BIOMAT 2007 written by Rubem Mondaini and published by World Scientific. This book was released on 2008 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present volume contains the contributions of the keynote speakers of the BIOMAT 2007 Symposium as well as selected contributed papers in the areas of mathematical biology, biological physics, biophysics and bioinformatics. It contains new results on some aspects of Lotka?Volterra equations, the proposal of using differential geometry to model neurosurgical tools, recent data on epidemiological modeling, pattern recognition and comprehensive reviews on the structure of proteins, the folding problem and the influence of Allee effects on population dynamics.This book contains some original results on the growth of gliomas: the role played by membrane channels on activity-dependent modulation of spike transmission; a proposal for reconsidering the concept of gene and the understanding of the mechanisms responsible for gene expression; a differential geometric approach to the influence of the drying effect on the dynamics of pods of Leguminosae; the comparison of agent-based models with the approach of differential equations on the study of selection mechanisms in germinal centers; and the synchronization phenomenon for protocell systems driven by linear kinetic equations.

Memorial Volume For Kerson Huang

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Author :
Publisher : #N/A
ISBN 13 : 9813207442
Total Pages : 145 pages
Book Rating : 4.8/5 (132 download)

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Book Synopsis Memorial Volume For Kerson Huang by : Kok Khoo Phua

Download or read book Memorial Volume For Kerson Huang written by Kok Khoo Phua and published by #N/A. This book was released on 2017-07-14 with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt: Professor Kerson Huang was a well respected theoretical physicist, who was also well versed in English and Chinese literature. He was born in Nanning, China, on 15 March 1928, and he was a fellow at the IAS, Princeton, from 1955-1957 before joining the faculty of MIT. He remained there until he retired from teaching in 1999. His research in theoretical physics included works on Bose-Einstein condensation and quantum field theory. In his long and illustrious career, Prof. Huang has worked with many prominent physicists. In 1957, he published a theory known as the hard-sphere model for Bose gases with Nobel Laureates Chen-Ning Yang and Tsung-Dao Lee. With Noble Laureate Steven Weinberg, he studied the ultimate temperature and the thermodynamics of early universe. While he was at Princeton, he also worked with atomic bomb developer J. Robert Oppenheimer. In recently years, Prof. Huang had been a visiting professor at Nanyang Technological University in Singapore, and worked on both biophysics and quantum cosmology.This memorial volume is dedicated to Prof. Huang who passed away peacefully at home on September 1, 2016 at the age of 88. The volume features the recollections of Prof. Huang by his former colleagues and students, including Profs Chen-Ning Yang and Samuel Ting, as well as their reflections on Prof. Huang's achievements in the various subdivisions of physics.

Protein Instability at Interfaces During Drug Product Development

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Publisher : Springer Nature
ISBN 13 : 3030571777
Total Pages : 338 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Protein Instability at Interfaces During Drug Product Development by : Jinjiang Li

Download or read book Protein Instability at Interfaces During Drug Product Development written by Jinjiang Li and published by Springer Nature. This book was released on 2021-02-12 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proteins are exposed to various interfacial stresses during drug product development. They are subjected to air-liquid, liquid-solid, and, sometimes, liquid-liquid interfaces throughout the development cycle-from manufacturing of drug substances to storage and drug delivery. Unlike small molecule drugs, proteins are typically unstable at interfaces where, on adsorption, they often denature and form aggregates, resulting in loss of efficacy and potential immunogenicity. This book covers both the fundamental aspects of proteins at interfaces and the quantification of interfacial behaviors of proteins. Importantly, this book introduces the industrial aspects of protein instabilities at interfaces, including the processes that introduce new interfaces, evaluation of interfacial instabilities, and mitigation strategies. The audience that this book targets encompasses scientists in the pharmaceutical and biotech industry, as well as faculty and students from academia in the surface science, pharmaceutical, and medicinal chemistry areas.

Frontiers of Applied Mathematics

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Publisher : World Scientific
ISBN 13 : 9812770453
Total Pages : 236 pages
Book Rating : 4.8/5 (127 download)

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Book Synopsis Frontiers of Applied Mathematics by : Din-Yu Hsieh

Download or read book Frontiers of Applied Mathematics written by Din-Yu Hsieh and published by World Scientific. This book was released on 2007 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume brings together articles on the mathematical aspects of life sciences, astrophysics, and nonlinear wave problems. It covers theoretical problems associated with the nervous system, drosophila embryos, protein folding, biopolymers, protoplanetary disks and extrasolar planets, gaseous disks, spiral galaxies, dark matter dynamics, star formation, solitary waves, photonics, and nonlinear light propagation in periodic media. The contributions are written for a general audience, and the authors have included references for further reading.