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Laser Induced Damage In Biological Tissue
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Book Synopsis Laser-induced Damage in Biological Tissue by : Elharith M. Ahmed
Download or read book Laser-induced Damage in Biological Tissue written by Elharith M. Ahmed and published by . This book was released on 2013 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since its invention in the early 1960's, the laser has been used as a tool for surgical, therapeutic, and diagnostic purposes. To achieve maximum effectiveness with the greatest margin of safety it is important to understand the mechanisms of light propagation through tissue and how that light affects living cells. Lasers with novel output characteristics for medical and military applications are too often implemented prior to proper evaluation with respect to tissue optical properties and human safety. Therefore, advances in computational models that describe light propagation and the cellular responses to laser exposure, without the use of animal models, are of considerable interest. Here, a physics-based laser-tissue interaction model was developed to predict the spatial and temporal temperature and pressure rise during laser exposure to biological tissues. Our new model also takes into account the dynamic nature of tissue optical properties and their impact on the induced temperature and pressure profiles. The laser-induced retinal damage is attributed to the formation of microbubbles formed around melanosomes in the retinal pigment epithelium (RPE) and the damage mechanism is assumed to be photo-thermal. Selective absorption by melanin creates these bubbles that expand and collapse around melanosomes, destroying cell membranes and killing cells. The Finite Element (FE) approach taken provides suitable ground for modeling localized pigment absorption which leads to a non-uniform temperature distribution within pigmented cells following laser pulse exposure. These hot-spots are sources for localized thermo-elastic stresses which lead to rapid localized expansions that manifest themselves as microbubbles and lead to microcavitations. Model predictions for the interaction of lasers at wavelengths of 193, 694, 532, 590, 1314, 1540, 2000, and 2940 nm with biological tissues were generated and comparisons were made with available experimental data for the retina, cornea or the skin. Good agreement between model and experimental results established the validity of the model.
Book Synopsis Laser-Tissue Interactions by : Markolf Niemz
Download or read book Laser-Tissue Interactions written by Markolf Niemz and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: Laser--Tissue Interactions provides a thorough description of the fundamentals and applications in this field. Basic conceptions such as optical and thermal properties of tissue, various types of tissue ablation, and optical breakdown with related effects are treated in detail. Special attention is given to mathematical tools (Monte Carlo simulations, Kubelka--Munk theory) and approved techniques (photodynamic therapy, laser-induced interstitial thermotherapy). The part on applications reviews clinically relevant methods in modern medicine according to the latest references. The last chapter includes today's standards of laser safety, with a careful selection of essential guidelines published
Book Synopsis Laser-Tissue Interactions by : Markolf H. Niemz
Download or read book Laser-Tissue Interactions written by Markolf H. Niemz and published by Springer Science & Business Media. This book was released on 2007-08-27 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical practitioners, scientists and graduate students alike will find this exhaustive survey a vital learning tool. It provides a thorough description of the fundamentals and applications in the field of laser-tissue interactions. Basic concepts such as the optical and thermal properties of tissue, the various types of tissue ablation, and optical breakdown and its related effects are treated in detail. The author pays special attention to mathematical tools (Monte Carlo simulations, the Kubelka-Munk theory etc.) and approved techniques (photodynamic therapy, laser-induced interstitial thermotherapy etc.). A section on applications reviews clinically relevant methods in modern medicine using the latest references.
Book Synopsis Primary and Secondary Damage Induced to Biological Tissue by Laser Radiation by : G. Laufer
Download or read book Primary and Secondary Damage Induced to Biological Tissue by Laser Radiation written by G. Laufer and published by . This book was released on 1982 with total page 21 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Applied Laser Medicine by : H. Breuer
Download or read book Applied Laser Medicine written by H. Breuer and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 762 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook is intended for the advanced specialist and for the practitioner interested in the application of lasers in medicine. It provides summaries of all available medical laser systems and their clinical use. The first part introduces basic laser physics, including laser-tissue interactions as well as technical equipment and particular techniques developed for medical use in connection with laser. The second part of the text covers all areas of laser application in medicine and has been written by senior specialists from different countries. The book includes about 300 line drawings, more than 100 high quality photographs, an extensive subject and author register, and an exhaustive list of references.
Book Synopsis Laser Induced Plasma Ablation of Biological Tissue by : Jill M. Tobin
Download or read book Laser Induced Plasma Ablation of Biological Tissue written by Jill M. Tobin and published by . This book was released on 1985 with total page 94 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Laser Applications in Medicine and Biology by : M.L. Wolbarsht
Download or read book Laser Applications in Medicine and Biology written by M.L. Wolbarsht and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use oflasers has entered almost every facet of medicine and biology. Therefore, it is to be expected that the reviews contained in this vol urne will reflect this diversity. As dinical acceptance has grown with various diagnostic and therapeutic applications, so has the need for a more thorough understanding of the theoretical background for each. This is especially true where a correlation is to be made between the theoretical background and the experimental data. It is only in this way that we can attain the optimal form of any therapy. The basic coupling ofenergy into biological tissue and its conversion into heat is characterized by many parameters. One ofthe most important is pulse duration. The review by Bimgruber in Chapter 6 shows how our knowledge ofthis parameter has been extended.The need for a more basic understanding of the interaction of electromagnetic energy with various kinds of materials has led to investigations on the nature of plasmas their stability and instability,and how theyexist. Docchio reviews the factors that cause them to occur at a specific locale and then to move away from that site. The availabilityofmany types ofoptical fibers has extended our ability to deliver laser energy from various types oflasers into almost anyselected location. This is particularly useful in medicine, where less invasive ap proaches to surgery and diagnosis are always helpful. However, as Rol and his colleagues explain, the power-handling capabilities ofoptical fibers limit many applications, particularly for short-duration, high-peak-power laser pulses.
Download or read book 昭和二年七月興行繪本筋書 written by and published by . This book was released on 1927 with total page 16 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Laser-induced Interstitial Thermotherapy by : Gerhard J. Müller
Download or read book Laser-induced Interstitial Thermotherapy written by Gerhard J. Müller and published by SPIE Press. This book was released on 1995 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Modeling of the Laser-Induced Thermal Response, Ablation, and Fragmentation of Biological Tissue by :
Download or read book Modeling of the Laser-Induced Thermal Response, Ablation, and Fragmentation of Biological Tissue written by and published by . This book was released on 1988 with total page 75 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report describes the modeling activities carried out by Physical Sciences Inc. (PSI) during the first year of our ONR Contract N0014-87-C-0161. The objective of this contract is to develop models which can ultimately be used to predict the thermal response, ablation, and fragmentation of hard and soft biological tissue exposed to free electron laser (FEL) radiation. Most of our efforts thus far have been focused on the hard tissue problem, i.e., kidney stones, gallstones, calcified plaque. During this first year of the program modeling efforts have been initiated in four principal areas: (1) further development and application of 1-D and 2-D numerical heat conduction codes to model the thermal damage and ablation of soft tissue exposed to infrared laser energy, (2) modeling of plasma initiation mechanisms in, and resulting plasma spectral emissions from, pulsed laser-irradiated kidney stones and gallstones, (3) modeling of laser-driven shock-induced fragmentation of kidney stones and gallstones, and (4) modeling of the above surface hydrodynamics, i.e., bubble growth and acoustic wave propagation, resulting from plasma-mediated laser energy deposition above a hard tissue surface in a fluid medium.
Book Synopsis Proceedings of Laser-tissue Interaction by :
Download or read book Proceedings of Laser-tissue Interaction written by and published by . This book was released on 1995 with total page 692 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Theoretical Modeling of Damage Mechanisms for Ultrashort Laser Pulses in Ocular Media by :
Download or read book Theoretical Modeling of Damage Mechanisms for Ultrashort Laser Pulses in Ocular Media written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The funding provided in this grant has allowed the development of a comprehensive computational model for predicting the effect that any laser pulse will have on any spherical absorbing particle. This model is based upon fundamental principles an(therefore is capable of determining all thermomechanical responses (temperature rise, shock wave, explosive vaporization) and is applicable to a wide range of materials with unprecedented accuracy. This allows the assessment of potential damage to a variety of materials, such as biological tissue. The computational model is also applicable for investigating and predicting laser induced damage in synthetic polymers and optical and electronic communication materials. The research also furnishes a technique for determining thermomechanical properties of microparticles used in novel medical, biological and material science applications. In addition, we have seen evidence that the thermomechanical response in various materials to a laser pulse is not only non-linear, but chaotic. This implies that small changes in laser pulse characteristics such as duration or energy may lead to enormous changes in response that are extremely damaging to the material whether biological or synthetic. The detailed nature of the investigation and resulting model allowed for the discovery of this chaotic behavior, which had not been previously reported by any other investigators.
Book Synopsis Laser Induced Damage in Optical Materials by :
Download or read book Laser Induced Damage in Optical Materials written by and published by . This book was released on 1994 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Laser Microirradiation of Cells by : Takahiro Kasuya
Download or read book Laser Microirradiation of Cells written by Takahiro Kasuya and published by Routledge. This book was released on 1989 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt: First volume in a new series designed to provide information quickly on current as well as promising developments in lasers and consisting of self-contained tracts and handbooks pertinent to laser science and technology. Five color plates. Annotation copyrighted by Book News, Inc., Portland, OR
Book Synopsis Laser Manipulation of Cells and Tissues by : Michael W. Berns
Download or read book Laser Manipulation of Cells and Tissues written by Michael W. Berns and published by Academic Press. This book was released on 2007-06-20 with total page 824 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of laser-based manipulation tools has literally exploded on the cell biology and molecular pathology scene, resulting in as many different laser micromanipulation systems as there are people using them. Laser Manipulation of Cells and Tissues ties all these systems and studies together, describing all of the different kinds of research and practical/analytical applications of laser manipulation. It also provides the reader with the basic information needed to actually build one's own laser micro-manipulation system. The combination of imaging and molecular probe technology with laser micromanipulation greatly extends the use of this technology in molecular, cellular, developmental and patho-biology/medicine. This book should be valuable to scientists, clinicians, and students in the fields of cell and developmental biology, cell physiology, cancer biology, pathology, and stem cell biology. Devotes four chapters to laser catapulting and capture of DNA and other cellular material for biochemical analysis - a major use of this technology that has been adapted for molecular pathology both in clinical medicine and research Discusses the theory of laser tweezers (optical tweezers) and its application to novel problems in biology Covers topics on optoporation (getting things into cells), uncaging of molecules, and the ability to collect and analyze nanomolar amounts of cell material by an array of biochemical/physical tools of particular interest to cell biologists and drug discovery researchers
Book Synopsis Heat Transfer in Medicine and Biology by : R.C. Eberhart
Download or read book Heat Transfer in Medicine and Biology written by R.C. Eberhart and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Pulsed laser ablation of biological tissue by : Eric Duco Jansen
Download or read book Pulsed laser ablation of biological tissue written by Eric Duco Jansen and published by . This book was released on 1994 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt:
