Laboratory-based survey of acquired HIV drug resistance using remnant viral load specimens

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Author :
Publisher : World Health Organization
ISBN 13 : 9240025413
Total Pages : 91 pages
Book Rating : 4.2/5 (4 download)

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Book Synopsis Laboratory-based survey of acquired HIV drug resistance using remnant viral load specimens by :

Download or read book Laboratory-based survey of acquired HIV drug resistance using remnant viral load specimens written by and published by World Health Organization. This book was released on 2021-06-29 with total page 91 pages. Available in PDF, EPUB and Kindle. Book excerpt: WHO’s laboratory-based acquired drug resistance survey method yields robust estimates of acquired HIV drug resistance in adults, children and adolescents taking both dolutegravir and non-dolutegravir based regimens by genotyping remnant specimens from routine viral load testing. Results are used to inform programme decision making regarding optimal ART regimens and support evaluation of programme quality with respect to maximizing viral load suppression and minimizing emergence of resistance in people taking ART.

LABORATORY-BASED SURVEY OF ACQUIRED HIV DRUG RESISTANCE USING REMNANT VIRAL LOAD SPECIMENS.

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (139 download)

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Book Synopsis LABORATORY-BASED SURVEY OF ACQUIRED HIV DRUG RESISTANCE USING REMNANT VIRAL LOAD SPECIMENS. by : World Health Organization

Download or read book LABORATORY-BASED SURVEY OF ACQUIRED HIV DRUG RESISTANCE USING REMNANT VIRAL LOAD SPECIMENS. written by World Health Organization and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Sentinel surveys of acquired HIV resistance to dolutegravir among people receiving dolutegravir-containing antiretroviral therapy

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Publisher : World Health Organization
ISBN 13 : 924006320X
Total Pages : 28 pages
Book Rating : 4.2/5 (4 download)

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Book Synopsis Sentinel surveys of acquired HIV resistance to dolutegravir among people receiving dolutegravir-containing antiretroviral therapy by : World Health Organization

Download or read book Sentinel surveys of acquired HIV resistance to dolutegravir among people receiving dolutegravir-containing antiretroviral therapy written by World Health Organization and published by World Health Organization. This book was released on 2022-11-22 with total page 28 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Clinic-based survey of acquired HIV drug resistance

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Publisher : World Health Organization
ISBN 13 : 9240035001
Total Pages : 60 pages
Book Rating : 4.2/5 (4 download)

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Book Synopsis Clinic-based survey of acquired HIV drug resistance by :

Download or read book Clinic-based survey of acquired HIV drug resistance written by and published by World Health Organization. This book was released on 2021-09-20 with total page 60 pages. Available in PDF, EPUB and Kindle. Book excerpt:

HIV drug resistance strategy, 2021 update

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Author :
Publisher : World Health Organization
ISBN 13 : 9240030565
Total Pages : 36 pages
Book Rating : 4.2/5 (4 download)

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Book Synopsis HIV drug resistance strategy, 2021 update by :

Download or read book HIV drug resistance strategy, 2021 update written by and published by World Health Organization. This book was released on 2020-07-23 with total page 36 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Target product profile for HIV drug resistance tests in low- and middle-income countries: Africa

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Author :
Publisher : World Health Organization
ISBN 13 : 9240076662
Total Pages : 30 pages
Book Rating : 4.2/5 (4 download)

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Book Synopsis Target product profile for HIV drug resistance tests in low- and middle-income countries: Africa by : World Health Organization

Download or read book Target product profile for HIV drug resistance tests in low- and middle-income countries: Africa written by World Health Organization and published by World Health Organization. This book was released on 2023-09-12 with total page 30 pages. Available in PDF, EPUB and Kindle. Book excerpt: HIV-1 drug resistance tests may be useful tools for optimizing ART regimens when used in the context of information about viral load, immune and clinical status, adherence practices and available treatment options. Several types of drug resistance tests are available, either as commercial kits or based on published methods for in-house assays. The target product profile for HIV drug resistance tests in low- and middle-income countries: Africa is designed to guide the development of new HIV drug resistance tests in the era of dolutegravir-based antiretroviral therapy (ART) and to facilitate the evaluation of the suitability of currently available HIV drug resistance tests for specific applications. The target product profiles focus on the new-term future for available ART regimens and their use and anticipates an innovate test that will meet the projected demand.

HIV drug resistance

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Author :
Publisher : World Health Organization
ISBN 13 : 9240086315
Total Pages : 46 pages
Book Rating : 4.2/5 (4 download)

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Book Synopsis HIV drug resistance by : World Health Organization

Download or read book HIV drug resistance written by World Health Organization and published by World Health Organization. This book was released on 2024-03-01 with total page 46 pages. Available in PDF, EPUB and Kindle. Book excerpt: This brief report summarizes recent information on HIV drug resistance (HIVDR) in the era of integrase-strand transfer inhibitors (INSTI) for HIV prevention and treatment. In this report, WHO documents high levels of HIV viral load suppression (>90%) in populations receiving dolutegravir (DTG)-containing antiretroviral therapy (ART). However, recent observational data reveal that HIVDR to DTG is emerging at levels exceeding those observed in clinical trials. Few countries have reported people not achieving viral suppression while receiving DTG-containing ART. However, amongst the surveys reported, levels of DTG resistance ranged from 3.9% to 8.6%, with levels as high as 19.6% observed among highly treatment-experienced people who transitioned to a DTG-containing ART while having high HIV viral loads. Levels of observed DTG resistance in real world populations receiving ART appear to be higher than anticipated from clinical trials. WHO recommends that countries routinely implement standardised surveillance of HIVDR to follow the prevalence and patterns of resistance among people not achieving suppressed viral load. The use of long acting cabotegravir (CAB-LA) for pre-exposure prophylaxis (PrEP) greatly reduces the risk of acquiring HIV. However, INSTI resistance has been observed in some cases with recent CAB-LA exposure, and delayed detection and confirmation of HIV infection can increase the risk of selection of INSTI drug resistance–associated mutations. Despite the possible risk, the roll-out of CAB-LA for PrEP should not be hindered. Scale-up of PrEP should be accompanied by standardized surveillance of drug resistance among people testing positive for HIV while receiving PrEP.

WHO HIV drug resistance network steering group meeting report June 2021

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Author :
Publisher : World Health Organization
ISBN 13 : 924003854X
Total Pages : 22 pages
Book Rating : 4.2/5 (4 download)

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Book Synopsis WHO HIV drug resistance network steering group meeting report June 2021 by :

Download or read book WHO HIV drug resistance network steering group meeting report June 2021 written by and published by World Health Organization. This book was released on 2021-11-22 with total page 22 pages. Available in PDF, EPUB and Kindle. Book excerpt:

HIV drug resistance report 2021

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Author :
Publisher : World Health Organization
ISBN 13 : 9240038604
Total Pages : 138 pages
Book Rating : 4.2/5 (4 download)

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Book Synopsis HIV drug resistance report 2021 by :

Download or read book HIV drug resistance report 2021 written by and published by World Health Organization. This book was released on 2021-11-24 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt:

WHO HIVResNet meeting report, Johannesburg, South Africa, 19 October 2019

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Publisher : World Health Organization
ISBN 13 : 9240019421
Total Pages : 40 pages
Book Rating : 4.2/5 (4 download)

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Book Synopsis WHO HIVResNet meeting report, Johannesburg, South Africa, 19 October 2019 by :

Download or read book WHO HIVResNet meeting report, Johannesburg, South Africa, 19 October 2019 written by and published by World Health Organization. This book was released on 2021-02-15 with total page 40 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Report on the global action plan on HIV drug resistance 2017–2021

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Author :
Publisher : World Health Organization
ISBN 13 : 9240071083
Total Pages : 40 pages
Book Rating : 4.2/5 (4 download)

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Book Synopsis Report on the global action plan on HIV drug resistance 2017–2021 by : World Health Organization

Download or read book Report on the global action plan on HIV drug resistance 2017–2021 written by World Health Organization and published by World Health Organization. This book was released on 2023-05-01 with total page 40 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Consolidated guidelines on HIV prevention, testing, treatment, service delivery and monitoring

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Publisher : World Health Organization
ISBN 13 : 9240031596
Total Pages : 592 pages
Book Rating : 4.2/5 (4 download)

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Book Synopsis Consolidated guidelines on HIV prevention, testing, treatment, service delivery and monitoring by : World Health Organization

Download or read book Consolidated guidelines on HIV prevention, testing, treatment, service delivery and monitoring written by World Health Organization and published by World Health Organization. This book was released on 2021-07-16 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: These consolidated guidelines on HIV prevention, testing, treatment, service delivery and monitoring bring together existing and new clinical and programmatic recommendations across different ages, populations and settings, bringing together all relevant WHO guidance on HIV produced since 2016. It serves as an update to the previous edition of the consolidated guidelines on HIV. These guidelines continue to be structured along the continuum of HIV care. Information on new combination prevention approaches, HIV testing, ARV regimens and treatment monitoring are included. There is a new chapter on advanced HIV disease that integrates updated guidance on the management of important HIV comorbidities, including cryptococcal disease, histoplasmosis and tuberculosis. The chapter on general HIV care, contains a new section on palliative care and pain management, and up to date information on treatment of several neglected tropical diseases, such as visceral leishmaniasis and Buruli ulcer. New recommendations for screening and treating of cervical pre-cancer lesions in women living with HIV are also addressed in this chapter. Guidance on service delivery was expanded to help the implementation and strengthening the HIV care cascade. Importantly, this guidance emphasizes the need for differentiated approaches to care for people who are established on ART, such as reduced frequency of clinic visits, use of multi-month drug dispensing and implementation of community ART distribution. The adoption of these efficiencies is essential to improve the quality of care of people receiving treatment and reduce the burden on health facilities, particularly in resource limited settings.

Priorities for antiretroviral drug optimization in adults and children

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Publisher : World Health Organization
ISBN 13 : 9240053034
Total Pages : 34 pages
Book Rating : 4.2/5 (4 download)

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Book Synopsis Priorities for antiretroviral drug optimization in adults and children by : World Health Organization

Download or read book Priorities for antiretroviral drug optimization in adults and children written by World Health Organization and published by World Health Organization. This book was released on 2022-06-30 with total page 34 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Consolidated guidelines on person-centred HIV strategic information

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Author :
Publisher : World Health Organization
ISBN 13 : 9240055312
Total Pages : 424 pages
Book Rating : 4.2/5 (4 download)

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Book Synopsis Consolidated guidelines on person-centred HIV strategic information by : World Health Organization

Download or read book Consolidated guidelines on person-centred HIV strategic information written by World Health Organization and published by World Health Organization. This book was released on 2022-07-29 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: These consolidated guidelines are aimed at supporting the generation of responsive person-centred data from routine national health management information systems across the HIV cascade, from prevention, testing and treatment to longer-term health care. They build upon the 2017 Consolidated guidelines on person-centred HIV patient monitoring and case surveillance, which describe information that should be collected in primary HIV patient monitoring tools, and the 2020 Consolidated HIV strategic information guidelines, which cover aggregate indicators for managing and monitoring programmes. The purpose of this guideline consolidation is to provide the recommended data elements, indicators and guidance on data systems and their use across the spectrum of health sector HIV services in one place. This document focuses on strengthening the analysis and use of routine data at each stage of the cascade and emphasizes?/addresses? person-centred HIV prevention, testing and treatment, integration of HIV-related infections, the use of routine surveillance data to measure impact, and the development and use of digital health data systems and their governance. It also identifies the gaps and limitations in these data, and the need for strengthening the use of data in all HIV-related strategic information, including population-based surveys, modelling, community-led monitoring and other sources.

Disease Control Priorities, Third Edition (Volume 6)

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Author :
Publisher : World Bank Publications
ISBN 13 : 1464805253
Total Pages : 1027 pages
Book Rating : 4.4/5 (648 download)

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Book Synopsis Disease Control Priorities, Third Edition (Volume 6) by : King K. Holmes

Download or read book Disease Control Priorities, Third Edition (Volume 6) written by King K. Holmes and published by World Bank Publications. This book was released on 2017-11-06 with total page 1027 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

WHO Guidelines on Hand Hygiene in Health Care

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Publisher : World Health Organization
ISBN 13 : 9789241597906
Total Pages : 0 pages
Book Rating : 4.5/5 (979 download)

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Book Synopsis WHO Guidelines on Hand Hygiene in Health Care by : World Health Organization

Download or read book WHO Guidelines on Hand Hygiene in Health Care written by World Health Organization and published by World Health Organization. This book was released on 2009 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The WHO Guidelines on Hand Hygiene in Health Care provide health-care workers (HCWs), hospital administrators and health authorities with a thorough review of evidence on hand hygiene in health care and specific recommendations to improve practices and reduce transmission of pathogenic microorganisms to patients and HCWs. The present Guidelines are intended to be implemented in any situation in which health care is delivered either to a patient or to a specific group in a population. Therefore, this concept applies to all settings where health care is permanently or occasionally performed, such as home care by birth attendants. Definitions of health-care settings are proposed in Appendix 1. These Guidelines and the associated WHO Multimodal Hand Hygiene Improvement Strategy and an Implementation Toolkit (http://www.who.int/gpsc/en/) are designed to offer health-care facilities in Member States a conceptual framework and practical tools for the application of recommendations in practice at the bedside. While ensuring consistency with the Guidelines recommendations, individual adaptation according to local regulations, settings, needs, and resources is desirable. This extensive review includes in one document sufficient technical information to support training materials and help plan implementation strategies. The document comprises six parts.

Tietz Clinical Guide to Laboratory Tests - E-Book

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 1437719872
Total Pages : 1857 pages
Book Rating : 4.4/5 (377 download)

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Book Synopsis Tietz Clinical Guide to Laboratory Tests - E-Book by : Alan H. B. Wu

Download or read book Tietz Clinical Guide to Laboratory Tests - E-Book written by Alan H. B. Wu and published by Elsevier Health Sciences. This book was released on 2006-06-08 with total page 1857 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new edition of Norbert Tietz's classic handbook presents information on common tests as well as rare and highly specialized tests and procedures - including a summary of the utility and merit of each test. Biological variables that may affect test results are discussed, and a focus is placed on reference ranges, diagnostic information, clinical interpretation of laboratory data, interferences, and specimen types. New and updated content has been added in all areas, with over 100 new tests added. - Tests are divided into 8 main sections and arranged alphabetically. - Each test includes necessary information such as test name (or disorder) and method, specimens and special requirements, reference ranges, chemical interferences and in vivo effects, kinetic values, diagnostic information, factors influencing drug disposition, and clinical comments and remarks. - The most current and relevant tests are included; outdated tests have been eliminated. - Test index (with extensive cross references) and disease index provide the reader with an easy way to find necessary information - Four new sections in key areas (Preanalytical, Flow Cytometry, Pharmacogenomics, and Allergy) make this edition current and useful. - New editor Alan Wu, who specializes in Clinical Chemistry and Toxicology, brings a wealth of experience and expertise to this edition. - The Molecular Diagnostics section has been greatly expanded due to the increased prevalence of new molecular techniques being used in laboratories. - References are now found after each test, rather than at the end of each section, for easier access.