Kidney Biomarkers Clinical Aspects

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Kidney Biomarkers

Author : Seema S. Ahuja
Publisher : Academic Press
ISBN 13 : 0128163747
Total Pages : 344 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Kidney Biomarkers by : Seema S. Ahuja

Download or read book Kidney Biomarkers written by Seema S. Ahuja and published by Academic Press. This book was released on 2020-07-16 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since laboratory testing and biomarkers are an integral part in the diagnosis and treatment of kidney disease, Kidney Biomarkers: Clinical Aspects and Laboratory Determination covers currently used biomarkers as well as markers that are in development. Laboratories are increasingly more involved in the follow-up confirmatory laboratory testing and this unique volume showcases the collaboration needed to solve diagnostic clinical puzzles between the laboratory and clinician. This volume provides guidance on laboratory test selection and results interpretation in patients. Sources of inaccurate results in the measurement of kidney biomarkers are discussed along with possibility of eliminating such interferences. Each chapter is organized with a uniform easy-to-follow format with insightful case examples highlighting the collaboration between clinical laboratorians and clinicians. Categorizes biomarkers into diagnostic markers, disease follow-up markers, and prognostic biomarkers Include case examples to show the collaboration between the clinical laboratorian and clinician Discusses the application of kidney biomarkers in clinical practice along with addressing laboratory aspects of kidney biomarker determination

Kidney Biomarkers: Clinical Aspects

Author : Kristina Camarillo
Publisher : Murphy & Moore Publishing
ISBN 13 : 9781639877911
Total Pages : 0 pages
Book Rating : 4.8/5 (779 download)

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Book Synopsis Kidney Biomarkers: Clinical Aspects by : Kristina Camarillo

Download or read book Kidney Biomarkers: Clinical Aspects written by Kristina Camarillo and published by Murphy & Moore Publishing. This book was released on 2023-09-19 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Renal diseases or kidney diseases are a set of chronic diseases or conditions that affect the functioning of the kidneys. They are classified into two major categories, namely, inflammatory kidney diseases (nephritis) or non-inflammatory kidney diseases (nephrosis). A biomarker or biologic marker is a measurable indicator of a specific biological state, particularly one relevant to the risk for, presence of, or stage of a disease. Biomarkers of renal diseases are used to screen and diagnose the activity of renal diseases, and guide molecularly targeted therapy or therapeutic response. The most accurate and promising biomarkers for detecting chronic kidney disease (CKD) are neutrophil gelatinase-associated lipocalin (NGAL), cystatin C and FGF-23. The risk stratification for the progression and mortality of kidney diseases can be improved by using ratio calculated by glomerular filtration rate (eGFR) and albuminuria (UACR). This book describes the most important biomarkers researched and studied in the context of renal diseases. Those in search of information to further their knowledge will be greatly assisted by it.

Biomarkers of Kidney Disease

Author : Charles L. Edelstein
Publisher : Academic Press
ISBN 13 : 0123756731
Total Pages : 455 pages
Book Rating : 4.1/5 (237 download)

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Book Synopsis Biomarkers of Kidney Disease by : Charles L. Edelstein

Download or read book Biomarkers of Kidney Disease written by Charles L. Edelstein and published by Academic Press. This book was released on 2010-10-27 with total page 455 pages. Available in PDF, EPUB and Kindle. Book excerpt: A biomarker is a molecule that is measured as a marker of normal biological processes, disease processes or the response to a diagnostic or therapeutic intervention. Kidney diseases like acute kidney injury, chronic kidney disease, diabetic nephropathy, glomerular disease, renal cancer and preeclampsia still have a high morbidity. Measurement of biomarkers in the blood or urine that detect patients at risk of kidney diseases or that detect kidney diseases in the earliest stage may ultimately result in preventative or earlier or more effective treatments for kidney diseases. Biomarkers of Kidney Disease reviews the basic and clinical research on biomarkers of the common kidney diseases including acute kidney injury, chronic kidney disease, renal cancer, diabetic nephropathy, glomerular disease and preeclampsia. The characteristics of an ideal biomarker of kidney diseases and statistical analysis of biomarker studies is detailed. The latest techniques for biomarker detection like metabolomics and proteomics is covered in the book. This comprehensive book details the latest advances made in the field of biomarker research and development in kidney diseases. The book is an ideal companion for those interested in biomarker research and development, proteomics and metabolomics, kidney diseases, statistical analysis, transplantation and preeclampsia. Presents a comprehensive, translational source for all aspects of renal biomarkers in one reference work Experts in renal disease biomarkers (from all areas of academic and medical research) take readers from the bench research (cellular and molecular mechanism) to new therapeutic approaches

Chronic Kidney Disease

Author : Thomas Rath
Publisher : BoD – Books on Demand
ISBN 13 : 953513843X
Total Pages : 307 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Chronic Kidney Disease by : Thomas Rath

Download or read book Chronic Kidney Disease written by Thomas Rath and published by BoD – Books on Demand. This book was released on 2018-02-21 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: Known worldwide, chronic kidney disease (CKD) is a disease that affects up to 4% of the population with increasing figures also in the developing countries. Life expectancy of patients affected by CKD is shortened compared to the overall population, and only a minority of patients reach end-stage renal disease (ESRD) with the need for dialysis or renal transplantation; death overtakes dialysis. In the 13 chapters, this book sheds light on the different aspects related to pathophysiology and clinical aspects of CKD, providing interesting insights into not only inflammation and cardiovascular risk but also the interplay of hormones and the functional aspects of endothelial function. In addition, chapters dealing with genetic aspects of polycystic kidney disease and also the clinical handling of patients with CKD and peritoneal dialysis will be beneficial for the open-minded reader.

Diabetic Nephropathy

Author : Joris J. Roelofs
Publisher : Springer
ISBN 13 : 3319935216
Total Pages : 540 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis Diabetic Nephropathy by : Joris J. Roelofs

Download or read book Diabetic Nephropathy written by Joris J. Roelofs and published by Springer. This book was released on 2018-10-29 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an overview of the most up-to-date research on diabetic nephropathy and the current understanding of its pathogenesis, clinical features and socio-economic developments. Written by leading experts in the field, it provides a comprehensive synthesis of clinical and pathophysiological aspects from a mechanism-based point of view, and reviews evidence-based treatment modalities for the prevention and management of diabetic nephropathy. In addition, closely related areas such as diabesity, diabetic eye disease and macrovascular involvement in diabetes are addressed. Diabetic Nephropathy will be of interest for nephrologists, diabetologists, internists, transplant physicians, public health professionals, basic scientists, geneticists, epidemiologists, pathologists, and molecular and cell biologists working in the field of diabetes and its complications.

Biomarkers in Kidney Transplantation

Author : Dr Smita Pattanaik
Publisher : Academic Press
ISBN 13 : 9780128240694
Total Pages : 0 pages
Book Rating : 4.2/5 (46 download)

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Book Synopsis Biomarkers in Kidney Transplantation by : Dr Smita Pattanaik

Download or read book Biomarkers in Kidney Transplantation written by Dr Smita Pattanaik and published by Academic Press. This book was released on 2024-12-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomarkers in Kidney Transplantation: Clinical Aspects and Laboratory Determination provides a focused study on traditional and emerging biomarkers to predict early rejection of kidney transplants supporting appropriate therapeutic interventions. Coverage includes predictive and diagnostic biomarkers for different types of rejections, including biomarkers of acute, chronic/sub chronic rejection or clinical rejection, T-cell mediated rejection, antibody mediated rejection and mixed rejection. Comparisons are provided for broad classification of pharmacokinetic versus pharmacodynamic biomarkers, and differentiation is shown between the susceptibility, diagnostic, predictive, prognostic and monitoring biomarkers. Coverage of the analytical aspects of biomarker measurement, the process of biomarker discovery and their clinical validation addresses both the clinical features of biomarkers as well as the pitfalls of determining such biomarkers in clinical laboratories. By combining all current markers known for kidney transplant in one collection, this easy-to-use reference is perfect for pathologists, clinical pharmacologists, clinical laboratory scientists and all physicians involved in organ transplantation, including immunologists and transplant surgeons.

Biomarkers in Chronic Kidney Disease - The Linkage Between Inflammation, Ventricular Dysfunction and Overhydration

Author : Olimpia Ortega
Publisher :
ISBN 13 : 9789533073774
Total Pages : pages
Book Rating : 4.0/5 (737 download)

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Book Synopsis Biomarkers in Chronic Kidney Disease - The Linkage Between Inflammation, Ventricular Dysfunction and Overhydration by : Olimpia Ortega

Download or read book Biomarkers in Chronic Kidney Disease - The Linkage Between Inflammation, Ventricular Dysfunction and Overhydration written by Olimpia Ortega and published by . This book was released on 2011 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Advances in Nephropathy

Author : Thomas Rath
Publisher :
ISBN 13 : 9781789842364
Total Pages : 204 pages
Book Rating : 4.8/5 (423 download)

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Book Synopsis Advances in Nephropathy by : Thomas Rath

Download or read book Advances in Nephropathy written by Thomas Rath and published by . This book was released on 2018 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Oxford Textbook of Clinical Nephrology

Author : Neil N. Turner
Publisher : Oxford University Press
ISBN 13 : 0191017655
Total Pages : 3045 pages
Book Rating : 4.1/5 (91 download)

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Book Synopsis Oxford Textbook of Clinical Nephrology by : Neil N. Turner

Download or read book Oxford Textbook of Clinical Nephrology written by Neil N. Turner and published by Oxford University Press. This book was released on 2015-10-29 with total page 3045 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fourth edition of the Oxford Textbook of Clinical Nephrology builds on the success and international reputation of the publication as an important resource for the practising clinician in the field. It provides practical, scholarly, and evidence-based coverage of the full spectrum of clinical nephrology, written by a global faculty of experts. The most relevant and important reference to clinical nephrology, this is an authoritative and comprehensive textbook combining the clinical aspects of renal disease essential to daily clinical practice with extensive information about the underlying basic science and current evidence available. Each section of the textbook has been critically and comprehensively edited under the auspices of a leading expert in the field. This new edition has been significantly expanded and reapportioned to reflect developments and new approaches to topics, and includes treatment algorithms to aid and enhance patient care where possible. The fourth edition offers increased focus on the medical aspects of transplantation, HIV-associated renal disease, and infection and renal disease, alongside entirely new sections on genetic topics and clinical and physiological aspects of fluid/electrolyte and tubular disorders. The emphasis throughout is on marrying advances in scientific research with clinical management. Richly illustrated throughout in full colour, this is a truly modern and attractive edition which reinforces the Oxford Textbook of Clinical Nephrology's position as an indispensable reference work of consistent quality and reliability. Enriched and refined by careful revision, this new edition continues the tradition of excellence. This print edition of The Oxford Textbook of Clinical Nephrology comes with a year's access to the online version on Oxford Medicine Online. By activating your unique access code, you can read and annotate the full text online, follow links from the references to primary research materials, and view, enlarge and download all the figures and tables. Oxford Medicine Online is mobile optimized for access when and where you need it.

Nephrology and Public Health Worldwide

Author : G.B. Silva Junior
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 331806937X
Total Pages : 369 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Nephrology and Public Health Worldwide by : G.B. Silva Junior

Download or read book Nephrology and Public Health Worldwide written by G.B. Silva Junior and published by Karger Medical and Scientific Publishers. This book was released on 2021-11-02 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nephrology is one of the fastest growing specialties in medicine. Nevertheless, kidney disease is one of the most serious unmet health needs in many countries. To provide healthcare access with the desirable equity worldwide, the nephrology community needs to discuss this public health issue and take part in decisions for elaboration of public health policies with more justice and equity. This book brings together key current public health problems that affect kidney function and illuminates them in contributions by an international group of nephrologists and general practitioners. The chapters review current knowledge and provide guidelines to manage these conditions and decrease the disease burden. At the end, developments in the digital era and their application to kidney disease treatment are synthesized, and a broader outlook on the future of nephrology is given. Ultimately, the publication aims to gather nephrology and public health expertise from researchers from all over the world, providing a broad vision of issues that must be discussed and overcome to guarantee a better treatment for patients with kidney diseases in the world today.

Controversies in Acute Kidney Injury

Author : John A. Kellum
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805598106
Total Pages : 267 pages
Book Rating : 4.8/5 (55 download)

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Book Synopsis Controversies in Acute Kidney Injury by : John A. Kellum

Download or read book Controversies in Acute Kidney Injury written by John A. Kellum and published by Karger Medical and Scientific Publishers. This book was released on 2011 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: A timely update Acute kidney injury (AKI) is a serious and as yet incompletely understood disorder in which sudden impairment of kidney function occurs secondary to one or more of a variety of underlying conditions. This disorder is very common in (elderly) ICU patients and is associated with very high mortality. Many of those who survive suffer from permanent kidney failure and other long-term morbidities, which may include cardiovascular disease and immune dysfunction. Epidemiologic evidence suggests that AKI is not a single disease, but a syndrome comprised of multiple, often coexisting, etiologies. Being usually part of multiorgan failure syndrome, it calls for multiple organ support therapy. The publication at hand contains sections on prerenal azotemia syndromes, dying of' or with' AKI, pathophysiology of sepsis- induced acute kidney injury, developments in prevention / treatment / rehabilitation, and renal support. Reporting the latest recommendations from experts, it provides valuable information for those that are interested in understanding the disorder and its treatment options.

Cancer Biomarkers: Clinical Aspects and Laboratory Determination

Author : Lakshmi V. Ramanathan
Publisher : Elsevier
ISBN 13 : 0128243031
Total Pages : 476 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Cancer Biomarkers: Clinical Aspects and Laboratory Determination by : Lakshmi V. Ramanathan

Download or read book Cancer Biomarkers: Clinical Aspects and Laboratory Determination written by Lakshmi V. Ramanathan and published by Elsevier. This book was released on 2022-06-07 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer Biomarkers: Clinical Aspects and Laboratory Determination provides a comprehensive overview of current biomarkers for cancer detection, monitoring and recurrence, focusing on emerging technologies, impacts on the field, and selected biomarkers currently used in clinical practice. The content highlights current laboratory tests used in the management of adult and pediatric cancer patients. In addition, it investigates the role of Circulating Tumor Cells and circulating tumor DNA as biomarkers in cancer management as well as cytokines in monitoring response to CAR T therapies. This title is a perfect reference for clinical pathologists, laboratory scientists, medical technologists, physicians specializing in oncology, internal medicine, family practice and transplant medicine, resident physicians, medical students, nurse practitioners and clinical chemists. Provides insights into the overall complexity that the cancer patient presents and how laboratory tests are used in the management of care Discusses current and new technologies applicable to cancer biomarker evaluation, including the use of non-traditional specimens like saliva, fluids and uterine lavage Reviews current trends in liquid biopsy and cancer biomarkers Provides a roadmap for bringing new technologies and markers from the bench to the bedside in the quest for finding the ideal tumor marker

Uremic Toxins

Author : Severin Ringoir
Publisher : Springer Science & Business Media
ISBN 13 : 1468454455
Total Pages : 292 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Uremic Toxins by : Severin Ringoir

Download or read book Uremic Toxins written by Severin Ringoir and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present book contains the Proceedings of a two day Symposium on Uremic Toxins organized at the University of Ghent in Belgium. A series of guest lectures, free communications and posters have been presented. An international audience of 163 scientists from 16 nationalities listened to and discussed extensively a spectrum of topics brought forward by colleagues and researchers who worked for many years in the field of Uremic Toxins. There is a striking contrast between all the new dialysis strategies available in the work to "clean" the uremic patients and the almost non-progression of our knowledge on uremic toxins in the past decade. In this sense the symposium was felt by all participants as a new start for the research in the biochemical field of the definition of uremia. If the present volume would stimulate new work in this field in order to define uremia, or identify the uremic toxins, the purpose of the organizers would be maximally fulfilled.

IgG4-Related Kidney Disease

Author : Takao Saito
Publisher : Springer
ISBN 13 : 4431556877
Total Pages : 298 pages
Book Rating : 4.4/5 (315 download)

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Book Synopsis IgG4-Related Kidney Disease by : Takao Saito

Download or read book IgG4-Related Kidney Disease written by Takao Saito and published by Springer. This book was released on 2016-11-09 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a detailed review of the pathological and imaging features, diagnosis and treatment of IgG4-Related Kidney Disease (IgG4-RKD). IgG4-related disease (IgG4-RD), which is characterized by an elevated serum IgG4 level and infiltration of systemic organs by IgG4 positive plasma cells, is a newly recognized systemic disease. Diverse renal manifestations including specific tubulointerstitial nephritis, membranous nephropathy, and tumor-like urological diseases extending to the pelvis and urinary tract in IgG4-RD have been reported and are recently attracting attention as IgG4-RKD. In this book, leading researchers in the field present the latest insights into the broad spectrum of IgG4-RKD characteristics. In addition, they provide a detailed explanation of the pathology of IgG4-RKD including comparisons between the kidney and other affected organs, such as the lacrimal, salivary glands and pancreas in the histopathological section. IgG4-Related Kidney Disease will have a major impact on future immunological and nephrological studies and offers a useful resource not only for nephrologists but also general physicians and investigators in related fields.

Monitoring Metabolic Status

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309091594
Total Pages : 469 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Monitoring Metabolic Status by : Institute of Medicine

Download or read book Monitoring Metabolic Status written by Institute of Medicine and published by National Academies Press. This book was released on 2004-08-29 with total page 469 pages. Available in PDF, EPUB and Kindle. Book excerpt: The U.S. military's concerns about the individual combat service member's ability to avoid performance degradation, in conjunction with the need to maintain both mental and physical capabilities in highly stressful situations, have led to and interest in developing methods by which commanders can monitor the status of the combat service members in the field. This report examines appropriate biological markers, monitoring technologies currently available and in need of development, and appropriate algorithms to interpret the data obtained in order to provide information for command decisions relative to the physiological "readiness" of each combat service member. More specifically, this report also provides responses to questions posed by the military relative to monitoring the metabolic regulation during prolonged, exhaustive efforts, where nutrition/hydration and repair mechanisms may be mismatched to intakes and rest, or where specific metabolic derangements are present.

The Detection of Biomarkers

Author : Sibel A. Ozkan
Publisher : Academic Press
ISBN 13 : 0128230754
Total Pages : 615 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis The Detection of Biomarkers by : Sibel A. Ozkan

Download or read book The Detection of Biomarkers written by Sibel A. Ozkan and published by Academic Press. This book was released on 2021-12-05 with total page 615 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reliable, precise and accurate detection and analysis of biomarkers remains a significant challenge for clinical researchers. Methods for the detection of biomarkers are rather complex, requiring pre-treatment steps before analysis can take place. Moreover, comparing various biomarker assays and tracing research progress in this area systematically is a challenge for researchers. The Detection of Biomarkers presents developments in biomarker detection, including methods tools and strategies, biosensor design, materials, and applications. The book presents methods, materials and procedures that are simple, precise, sensitive, selective, fast and economical, and therefore highly practical for use in clinical research scenarios. This volume situates biomarker detection in its research context and sets out future prospects for the area. Its 20 chapters offer a comprehensive coverage of biomarkers, including progress on nanotechnology, biosensor types, synthesis, immobilization, and applications in various fields. The book also demonstrates, for students, how to synthesize and immobilize biosensors for biomarker assay. It offers researchers real alternative and innovative ways to think about the field of biomarker detection, increasing the reliability, precision and accuracy of biomarker detection. Locates biomarker detection in its research context, setting out present and future prospects Allows clinical researchers to compare various biomarker assays systematically Presents new methods, materials and procedures that are simple, precise, sensitive, selective, fast and economical Gives innovative biomarker assays that are viable alternatives to current complex methods Helps clinical researchers who need reliable, precise and accurate biomarker detection methods

Continuous Renal Replacement Therapy

Author : John A. Kellum
Publisher : Oxford University Press
ISBN 13 : 019022553X
Total Pages : 329 pages
Book Rating : 4.1/5 (92 download)

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Book Synopsis Continuous Renal Replacement Therapy by : John A. Kellum

Download or read book Continuous Renal Replacement Therapy written by John A. Kellum and published by Oxford University Press. This book was released on 2016 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: Continuous Renal Replacement Therapy provides concise, evidence-based, bedside guidance for the management of critically ill patients with acute renal failure, offering quick reference answers to clinicians' questions about treatments and situations encountered in daily practice.