Issues In Medical Chemistry 2013 Edition

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Issues in Medical Chemistry: 2013 Edition

Author :
Publisher : ScholarlyEditions
ISBN 13 : 1490107568
Total Pages : 1225 pages
Book Rating : 4.4/5 (91 download)

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Book Synopsis Issues in Medical Chemistry: 2013 Edition by :

Download or read book Issues in Medical Chemistry: 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-05-01 with total page 1225 pages. Available in PDF, EPUB and Kindle. Book excerpt: Issues in Medical Chemistry / 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Physiology and Biochemistry. The editors have built Issues in Medical Chemistry: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Physiology and Biochemistry in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Medical Chemistry: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Basic Concepts in Medicinal Chemistry

Author : Marc Harrold
Publisher : ASHP
ISBN 13 : 1585283649
Total Pages : 405 pages
Book Rating : 4.5/5 (852 download)

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Book Synopsis Basic Concepts in Medicinal Chemistry by : Marc Harrold

Download or read book Basic Concepts in Medicinal Chemistry written by Marc Harrold and published by ASHP. This book was released on 2013-01-18 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicinal chemistry is a complex topic. Written in an easy to follow and conversational style, Basic Concepts in Medicinal Chemistry focuses on the fundamental concepts that govern the discipline of medicinal chemistry as well as how and why these concepts are essential to therapeutic decisions. The book emphasizes functional group analysis and the basics of drug structure evaluation. In a systematic fashion, learn how to identify and evaluate the functional groups that comprise the structure of a drug molecule and their influences on solubility, absorption, acid/base character, binding interactions, and stereochemical orientation. Relevant Phase I and Phase II metabolic transformations are also discussed for each functional group. Key features include: • Discussions on the roles and characteristics of organic functional groups, including the identification of acidic and basic functional groups. • How to solve problems involving pH, pKa, and ionization; salts and solubility; drug binding interactions; stereochemistry; and drug metabolism. • Numerous examples and expanded discussions for complex concepts. • Therapeutic examples that link the importance of medicinal chemistry to pharmacy and healthcare practice. • An overview of structure activity relationships (SARs) and concepts that govern drug design. • Review questions and practice problems at the end of each chapter that allow readers to test their understanding, with the answers provided in an appendix. Whether you are just starting your education toward a career in a healthcare field or need to brush up on your organic chemistry concepts, this book is here to help you navigate medicinal chemistry. About the Authors Marc W. Harrold, BS, Pharm, PhD, is Professor of Medicinal Chemistry at the Mylan School of Pharmacy, Duquesne University, Pittsburgh, PA. Professor Harrold is the 2011 winner of the Omicron Delta Kappa "Teacher of the Year" award at Duquesne University. He is also the two-time winner of the "TOPS" (Teacher of the Pharmacy School) award at the Mylan School of Pharmacy. Robin M. Zavod, PhD, is Associate Professor for Pharmaceutical Sciences at the Chicago College of Pharmacy, Midwestern University, Downers Grove, IL, where she was awarded the 2012 Outstanding Faculty of the Year award. Professor Zavod also serves on the adjunct faculty for Elmhurst College and the Illinois Institute of Technology. She currently serves as Editor-in-Chief of the journal Currents in Pharmacy Teaching and Learning.

Issues in Cardiovascular Medicine: 2013 Edition

Author :
Publisher : ScholarlyEditions
ISBN 13 : 1490106278
Total Pages : 1189 pages
Book Rating : 4.4/5 (91 download)

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Book Synopsis Issues in Cardiovascular Medicine: 2013 Edition by :

Download or read book Issues in Cardiovascular Medicine: 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-05-01 with total page 1189 pages. Available in PDF, EPUB and Kindle. Book excerpt: Issues in Cardiovascular Medicine / 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Cardiovascular Toxicology. The editors have built Issues in Cardiovascular Medicine: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Cardiovascular Toxicology in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Cardiovascular Medicine: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

The Organic Chemistry of Drug Design and Drug Action

Author : Richard B. Silverman
Publisher : Elsevier
ISBN 13 : 0080513379
Total Pages : 650 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis The Organic Chemistry of Drug Design and Drug Action by : Richard B. Silverman

Download or read book The Organic Chemistry of Drug Design and Drug Action written by Richard B. Silverman and published by Elsevier. This book was released on 2012-12-02 with total page 650 pages. Available in PDF, EPUB and Kindle. Book excerpt: Standard medicinal chemistry courses and texts are organized by classes of drugs with an emphasis on descriptions of their biological and pharmacological effects. This book represents a new approach based on physical organic chemical principles and reaction mechanisms that allow the reader to extrapolate to many related classes of drug molecules. The Second Edition reflects the significant changes in the drug industry over the past decade, and includes chapter problems and other elements that make the book more useful for course instruction. - New edition includes new chapter problems and exercises to help students learn, plus extensive references and illustrations - Clearly presents an organic chemist's perspective of how drugs are designed and function, incorporating the extensive changes in the drug industry over the past ten years - Well-respected author has published over 200 articles, earned 21 patents, and invented a drug that is under consideration for commercialization

HIV-1 Integrase

Author : Nouri Neamati
Publisher : John Wiley & Sons
ISBN 13 : 1118015363
Total Pages : 710 pages
Book Rating : 4.1/5 (18 download)

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Book Synopsis HIV-1 Integrase by : Nouri Neamati

Download or read book HIV-1 Integrase written by Nouri Neamati and published by John Wiley & Sons. This book was released on 2011-08-10 with total page 710 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book comprehensively covers the mechanisms of action and inhibitor design for HIV-1 integrase. It serves as a resource for scientists facing challenging drug design issues and researchers in antiviral drug discovery. Despite numerous review articles and isolated book chapters dealing with HIV-1 integrase, there has not been a single source for those working to devise anti-AIDS drugs against this promising target. But this book fills that gap and offers a valuable introduction to the field for the interdisciplinary scientists who will need to work together to design drugs that target HIV-1 integrase.

Chemistry Problems

Author : David E. Newton
Publisher : Walch Publishing
ISBN 13 : 9780825142666
Total Pages : 224 pages
Book Rating : 4.1/5 (426 download)

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Book Synopsis Chemistry Problems by : David E. Newton

Download or read book Chemistry Problems written by David E. Newton and published by Walch Publishing. This book was released on 2001 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edition includes acid-base chemistry and thermochemistry. Chemistry Problems is the authoritative resource for practice problems covering all the essentials. Includes: Atomic structure Stoichiometry Solutions chemistry, and Electrochemistry. Literally thousands of problems in this compendium build proficiency, analytical skills, and math skills. The text includes a complete answer key and reference to applicable web sites.

Foye's Principles of Medicinal Chemistry

Author : Thomas L. Lemke
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1609133455
Total Pages : 1521 pages
Book Rating : 4.6/5 (91 download)

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Book Synopsis Foye's Principles of Medicinal Chemistry by : Thomas L. Lemke

Download or read book Foye's Principles of Medicinal Chemistry written by Thomas L. Lemke and published by Lippincott Williams & Wilkins. This book was released on 2012-01-24 with total page 1521 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acclaimed by students and instructors alike, Foye's Principles of Medicinal Chemistry is now in its Seventh Edition, featuring updated chapters plus new material that meets the needs of today's medicinal chemistry courses. This latest edition offers an unparalleled presentation of drug discovery and pharmacodynamic agents, integrating principles of medicinal chemistry with pharmacology, pharmacokinetics, and clinical pharmacy. All the chapters have been written by an international team of respected researchers and academicians. Careful editing ensures thoroughness, a consistent style and format, and easy navigation throughout the text.

Issues in Cancer Drugs and Therapies: 2013 Edition

Author :
Publisher : ScholarlyEditions
ISBN 13 : 1490106197
Total Pages : 282 pages
Book Rating : 4.4/5 (91 download)

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Book Synopsis Issues in Cancer Drugs and Therapies: 2013 Edition by :

Download or read book Issues in Cancer Drugs and Therapies: 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-05-01 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: Issues in Cancer Drugs and Therapies / 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Gene Therapy. The editors have built Issues in Cancer Drugs and Therapies: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Gene Therapy in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Cancer Drugs and Therapies: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Comprehensive Inorganic Chemistry II

Author :
Publisher : Newnes
ISBN 13 : 0080965296
Total Pages : 7694 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Comprehensive Inorganic Chemistry II by :

Download or read book Comprehensive Inorganic Chemistry II written by and published by Newnes. This book was released on 2013-07-23 with total page 7694 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Inorganic Chemistry II, Nine Volume Set reviews and examines topics of relevance to today’s inorganic chemists. Covering more interdisciplinary and high impact areas, Comprehensive Inorganic Chemistry II includes biological inorganic chemistry, solid state chemistry, materials chemistry, and nanoscience. The work is designed to follow on, with a different viewpoint and format, from our 1973 work, Comprehensive Inorganic Chemistry, edited by Bailar, Emeléus, Nyholm, and Trotman-Dickenson, which has received over 2,000 citations. The new work will also complement other recent Elsevier works in this area, Comprehensive Coordination Chemistry and Comprehensive Organometallic Chemistry, to form a trio of works covering the whole of modern inorganic chemistry. Chapters are designed to provide a valuable, long-standing scientific resource for both advanced students new to an area and researchers who need further background or answers to a particular problem on the elements, their compounds, or applications. Chapters are written by teams of leading experts, under the guidance of the Volume Editors and the Editors-in-Chief. The articles are written at a level that allows undergraduate students to understand the material, while providing active researchers with a ready reference resource for information in the field. The chapters will not provide basic data on the elements, which is available from many sources (and the original work), but instead concentrate on applications of the elements and their compounds. Provides a comprehensive review which serves to put many advances in perspective and allows the reader to make connections to related fields, such as: biological inorganic chemistry, materials chemistry, solid state chemistry and nanoscience Inorganic chemistry is rapidly developing, which brings about the need for a reference resource such as this that summarise recent developments and simultaneously provide background information Forms the new definitive source for researchers interested in elements and their applications; completely replacing the highly cited first edition, which published in 1973

Medicinal Chemistry

Author : Erland Stevens
Publisher : Prentice Hall
ISBN 13 : 9780321710482
Total Pages : 418 pages
Book Rating : 4.7/5 (14 download)

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Book Synopsis Medicinal Chemistry by : Erland Stevens

Download or read book Medicinal Chemistry written by Erland Stevens and published by Prentice Hall. This book was released on 2014 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emphasizing applications of chemistry while reinforcing theory – especially in the areas of organic and physical chemistry – this new text prepares readers for career success in the pharmaceutical, medical, and biotech industries. Medicinal Chemistry: The Modern Drug Discovery Process delivers a comprehensive introduction to medicinal chemistry at an appropriate level of detail for a diverse range of readers. By highlighting the concepts and skills related to drug discovery, Stevens deepens readers' understanding of the knowledge and techniques necessary for their careers.

Clinical Chemistry

Author : Wendy L Arneson
Publisher : F.A. Davis
ISBN 13 : 0803618611
Total Pages : 605 pages
Book Rating : 4.8/5 (36 download)

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Book Synopsis Clinical Chemistry by : Wendy L Arneson

Download or read book Clinical Chemistry written by Wendy L Arneson and published by F.A. Davis. This book was released on 2007-01-25 with total page 605 pages. Available in PDF, EPUB and Kindle. Book excerpt: Meet the learning needs of today’s students with a brand-new style of textbook—designed to excite your students’ interest in clinical chemistry! Organized almost entirely around organ systems—to parallel the way physicians order tests—this groundbreaking text teaches the concepts and principles of clinical chemistry through realistic situations and scenarios. By integrating pathophysiology, biochemistry, and analytical chemistry for each major system, students clearly see the relevance of what they are learning to their future careers. This practical approach encourages them how to apply theoretical principles in the laboratory and to develop important critical-thinking skills.

Bioisosteres in Medicinal Chemistry

Author : Nathan Brown
Publisher : John Wiley & Sons
ISBN 13 : 3527654321
Total Pages : 249 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Bioisosteres in Medicinal Chemistry by : Nathan Brown

Download or read book Bioisosteres in Medicinal Chemistry written by Nathan Brown and published by John Wiley & Sons. This book was released on 2012-06-18 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written with the practicing medicinal chemist in mind, this is the first modern handbook to systematically address the topic of bioisosterism. As such, it provides a ready reference on the principles and methods of bioisosteric replacement as a key tool in preclinical drug development. The first part provides an overview of bioisosterism, classical bioisosteres and typical molecular interactions that need to be considered, while the second part describes a number of molecular databases as sources of bioisosteric identification and rationalization. The third part covers the four key methodologies for bioisostere identification and replacement: physicochemical properties, topology, shape, and overlays of protein-ligand crystal structures. In the final part, several real-world examples of bioisosterism in drug discovery projects are discussed. With its detailed descriptions of databases, methods and real-life case studies, this is tailor-made for busy industrial researchers with little time for reading, while remaining easily accessible to novice drug developers due to its systematic structure and introductory section.

Inorganic Chemistry

Author : J. E. House
Publisher : Academic Press
ISBN 13 : 0123851106
Total Pages : 848 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Inorganic Chemistry by : J. E. House

Download or read book Inorganic Chemistry written by J. E. House and published by Academic Press. This book was released on 2012-10-30 with total page 848 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook provides essential information for students of inorganic chemistry or for chemists pursuing self-study. The presentation of topics is made with an effort to be clear and concise so that the book is portable and user friendly. Inorganic Chemistry 2E is divided into five major themes (structure, condensed phases, solution chemistry, main group and coordination compounds) with several chapters in each. There is a logical progression from atomic structure to molecular structure to properties of substances based on molecular structures, to behavior of solids, etc. The author emphasizes fundamental principles-including molecular structure, acid-base chemistry, coordination chemistry, ligand field theory, and solid state chemistry -and presents topics in a clear, concise manner. There is a reinforcement of basic principles throughout the book. For example, the hard-soft interaction principle is used to explain hydrogen bond strengths, strengths of acids and bases, stability of coordination compounds, etc. The book contains a balance of topics in theoretical and descriptive chemistry. New to this Edition: New and improved illustrations including symmetry and 3D molecular orbital representationsExpanded coverage of spectroscopy, instrumental techniques, organometallic and bio-inorganic chemistryMore in-text worked-out examples to encourage active learning and to prepare students for their exams . Concise coverage maximizes student understanding and minimizes the inclusion of details students are unlikely to use. . Discussion of elements begins with survey chapters focused on the main groups, while later chapters cover the elements in greater detail. . Each chapter opens with narrative introductions and includes figures, tables, and end-of-chapter problem sets.

Essentials of Organic Chemistry

Author : Paul M. Dewick
Publisher : John Wiley & Sons
ISBN 13 : 1118681967
Total Pages : 711 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Essentials of Organic Chemistry by : Paul M. Dewick

Download or read book Essentials of Organic Chemistry written by Paul M. Dewick and published by John Wiley & Sons. This book was released on 2013-03-20 with total page 711 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essentials of Organic Chemistry is an accessible introduction to the subject for students of Pharmacy, Medicinal Chemistry and Biological Chemistry. Designed to provide a thorough grounding in fundamental chemical principles, the book focuses on key elements of organic chemistry and carefully chosen material is illustrated with the extensive use of pharmaceutical and biochemical examples. In order to establish links and similarities the book places prominence on principles and deductive reasoning with cross-referencing. This informal text also places the main emphasis on understanding and predicting reactivity rather than synthetic methodology as well as utilising a mechanism based layout and featuring annotated schemes to reduce the need for textual explanations. * tailored specifically to the needs of students of Pharmacy Medical Chemistry and Biological Chemistry * numerous pharmaceutical and biochemical examples * mechanism based layout * focus on principles and deductive reasoning This will be an invaluable reference for students of Pharmacy Medicinal and Biological Chemistry.

Clinical Toxicology, An Issue of Emergency Medicine Clinics of North America

Author : Daniel M Lugassy
Publisher : Elsevier Health Sciences
ISBN 13 : 032326655X
Total Pages : 297 pages
Book Rating : 4.3/5 (232 download)

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Book Synopsis Clinical Toxicology, An Issue of Emergency Medicine Clinics of North America by : Daniel M Lugassy

Download or read book Clinical Toxicology, An Issue of Emergency Medicine Clinics of North America written by Daniel M Lugassy and published by Elsevier Health Sciences. This book was released on 2014-02-28 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Emergency Medicine Clinics focuses on Clinical Toxicology and is edited by Drs. Daniel Lugassy and Silas Smith and includes such topics as Emerging Drugs of Abuse, Pediatric Toxicology; Dosing and Medical Errors and Child Abuse,The Approach to Toxin-Induced Coagulopathy,The Approach to Toxin-Induced Cardiovascular Failure, The Approach to Toxin-Induced Metabolic Acidosis, The Approach to Withdrawal Syndromes, The Approach to Radiation Exposure, and more.

Novel PET Radiotracers with Potential Clinical Applications, An Issue of PET Clinics

Author : Neil Vasdev
Publisher : Elsevier Health Sciences
ISBN 13 : 0323531458
Total Pages : 121 pages
Book Rating : 4.3/5 (235 download)

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Book Synopsis Novel PET Radiotracers with Potential Clinical Applications, An Issue of PET Clinics by : Neil Vasdev

Download or read book Novel PET Radiotracers with Potential Clinical Applications, An Issue of PET Clinics written by Neil Vasdev and published by Elsevier Health Sciences. This book was released on 2017-06-08 with total page 121 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of PET Clinics focuses on Radiotracers, and is edited by Drs. Neil Vasdev and Abass Alavi. Articles will include: PET/CT detection of HER2-positive metastases in patients with 89Zr-DFO-trastuzumab; uPAR-PET with 68Ga-NOTA-AE105: first clinical experience with a novel PET ligand; 64Cu-FBP8: A fibrin-targeted probe for imaging of thrombus; Imaging of synaptic density in the brain via synaptic vesicle glycoprotein 2A (SV2A) with a novel biomarker [11C]UCB-J; Neuroimaging of stress sensitive and neuroinflammatory targets in mood disorders; Impact of MR-based PET motion correction on the quantification of PET kinetic parameters in simultaneous cardiac PET-MR; Multimodal studies of the contributions of amyloid and tau burden to neurodegeneration in AD, FTD and Non-AD tauopathies; Imaging of prostate-specific membrane antigen (PSMA) using [18F]DCFPyL; Ga-68 GRPR antagonist imaging; and more!

Scalable Green Chemistry

Author : Stefan Koenig
Publisher : CRC Press
ISBN 13 : 9814364819
Total Pages : 378 pages
Book Rating : 4.8/5 (143 download)

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Book Synopsis Scalable Green Chemistry by : Stefan Koenig

Download or read book Scalable Green Chemistry written by Stefan Koenig and published by CRC Press. This book was released on 2013-09-11 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: Packed with real-world examples, this book illustrates the 12 principles of green chemistry. These diverse case studies demonstrate to scientists and students that beyond the theory, the challenges of green chemistry in pharmaceutical discovery and development remain an ongoing endeavor. By informing and welcoming additional practitioners to this m