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Investigation Of Experimental And Computational Approaches To Optimize The Bacterial Three Hybrid Assay
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Book Synopsis Computational Intelligence Paradigms for Optimization Problems Using MATLAB®/SIMULINK® by : S. Sumathi
Download or read book Computational Intelligence Paradigms for Optimization Problems Using MATLAB®/SIMULINK® written by S. Sumathi and published by CRC Press. This book was released on 2018-09-03 with total page 612 pages. Available in PDF, EPUB and Kindle. Book excerpt: Considered one of the most innovative research directions, computational intelligence (CI) embraces techniques that use global search optimization, machine learning, approximate reasoning, and connectionist systems to develop efficient, robust, and easy-to-use solutions amidst multiple decision variables, complex constraints, and tumultuous environments. CI techniques involve a combination of learning, adaptation, and evolution used for intelligent applications. Computational Intelligence Paradigms for Optimization Problems Using MATLAB®/ Simulink® explores the performance of CI in terms of knowledge representation, adaptability, optimality, and processing speed for different real-world optimization problems. Focusing on the practical implementation of CI techniques, this book: Discusses the role of CI paradigms in engineering applications such as unit commitment and economic load dispatch, harmonic reduction, load frequency control and automatic voltage regulation, job shop scheduling, multidepot vehicle routing, and digital image watermarking Explains the impact of CI on power systems, control systems, industrial automation, and image processing through the above-mentioned applications Shows how to apply CI algorithms to constraint-based optimization problems using MATLAB® m-files and Simulink® models Includes experimental analyses and results of test systems Computational Intelligence Paradigms for Optimization Problems Using MATLAB®/ Simulink® provides a valuable reference for industry professionals and advanced undergraduate, postgraduate, and research students.
Book Synopsis Novel Approaches in Microbiome Analyses and Data Visualization by : Jessica Galloway-Peña
Download or read book Novel Approaches in Microbiome Analyses and Data Visualization written by Jessica Galloway-Peña and published by Frontiers Media SA. This book was released on 2019-02-06 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: High-throughput sequencing technologies are widely used to study microbial ecology across species and habitats in order to understand the impacts of microbial communities on host health, metabolism, and the environment. Due to the dynamic nature of microbial communities, longitudinal microbiome analyses play an essential role in these types of investigations. Key questions in microbiome studies aim at identifying specific microbial taxa, enterotypes, genes, or metabolites associated with specific outcomes, as well as potential factors that influence microbial communities. However, the characteristics of microbiome data, such as sparsity and skewedness, combined with the nature of data collection, reflected often as uneven sampling or missing data, make commonly employed statistical approaches to handle repeated measures in longitudinal studies inadequate. Therefore, many researchers have begun to investigate methods that could improve incorporating these features when studying clinical, host, metabolic, or environmental associations with longitudinal microbiome data. In addition to the inferential aspect, it is also becoming apparent that visualization of high dimensional data in a way which is both intelligible and comprehensive is another difficult challenge that microbiome researchers face. Visualization is crucial in both the analysis and understanding of metagenomic data. Researchers must create clear graphic representations that give biological insight without being overly complicated. Thus, this Research Topic seeks to both review and provide novels approaches that are being developed to integrate microbiome data and complex metadata into meaningful mathematical, statistical and computational models. We believe this topic is fundamental to understanding the importance of microbial communities and provides a useful reference for other investigators approaching the field.
Book Synopsis Issues in Computation: 2011 Edition by :
Download or read book Issues in Computation: 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 1318 pages. Available in PDF, EPUB and Kindle. Book excerpt: Issues in Computation / 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Computation. The editors have built Issues in Computation: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Computation in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Computation / 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Book Synopsis Multi-objective Swarm Intelligence by : Satchidananda Dehuri
Download or read book Multi-objective Swarm Intelligence written by Satchidananda Dehuri and published by Springer. This book was released on 2015-03-10 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this book is to understand the state-of-the-art theoretical and practical advances of swarm intelligence. It comprises seven contemporary relevant chapters. In chapter 1, a review of Bacteria Foraging Optimization (BFO) techniques for both single and multiple criterions problem is presented. A survey on swarm intelligence for multiple and many objectives optimization is presented in chapter 2 along with a topical study on EEG signal analysis. Without compromising the extensive simulation study, a comparative study of variants of MOPSO is provided in chapter 3. Intractable problems like subset and job scheduling problems are discussed in chapters 4 and 7 by different hybrid swarm intelligence techniques. An attempt to study image enhancement by ant colony optimization is made in chapter 5. Finally, chapter 7 covers the aspect of uncertainty in data by hybrid PSO.
Book Synopsis Natural Computing in Computational Finance by : Anthony Brabazon
Download or read book Natural Computing in Computational Finance written by Anthony Brabazon and published by Springer Science & Business Media. This book was released on 2008-05-09 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural Computing in Computational Finance is a innovative volume containing fifteen chapters which illustrate cutting-edge applications of natural computing or agent-based modeling in modern computational finance. Following an introductory chapter the book is organized into three sections. The first section deals with optimization applications of natural computing demonstrating the application of a broad range of algorithms including, genetic algorithms, differential evolution, evolution strategies, quantum-inspired evolutionary algorithms and bacterial foraging algorithms to multiple financial applications including portfolio optimization, fund allocation and asset pricing. The second section explores the use of natural computing methodologies such as genetic programming, neural network hybrids and fuzzy-evolutionary hybrids for model induction in order to construct market trading, credit scoring and market prediction systems. The final section illustrates a range of agent-based applications including the modeling of payment card and financial markets. Each chapter provides an introduction to the relevant natural computing methodology as well as providing a clear description of the financial application addressed. The book was written to be accessible to a wide audience and should be of interest to practitioners, academics and students, in the fields of both natural computing and finance.
Book Synopsis Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays by : Franz J. Hock
Download or read book Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays written by Franz J. Hock and published by Springer Nature. This book was released on 2025-02 with total page 2751 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many aspects of drug safety have become an outstanding and even persistent issue and may occur during the process of both drug discovery and development. Until 15 years ago, drug discovery and evaluation was primarily a sequential process starting with the selection of the most pharmacologically active compound from a series of newly synthesized small molecule chemical series by means of distinctive pharmacological assays. Safety aspects were addressed by evaluation of the selected compound at high doses in a series of specific studies directed at indications other than the intended indication of the new compound. These tests are then followed by pharmacokinetic studies, which are primarily conducted to confirm whether the selected compound possesses a suitable half-life for sufficient exposure and efficacy and, whether it has the desired properties specificity to the intended route of administration. Safety aspects relied predominantly on the conduct of single and repeat toxicologydose studies, which inform changes in organ structure rather than organ function. Both toxicological and pharmacokinetic studies are adapted to the progress of studies in clinical pharmacology and clinical trials. The new edition of this well and broadly accepted reference work contains several innovative and distinguished chapters. This "sequential" strategy has been abandoned with this new version of the book for several reasons: - Of the possible multitude of negative effects that novel drugs may impart on organ function, e.g. ventricular tachy-arrhythmia, many are detected too late in non-clinical studies to inform clinicians. On the other hand, negative findings in chronic toxicity studies in animals may turn out to be irrelevant for human beings. - New scientific approaches, e.g. high-throughput screening, human pluripotent stem cells, transgenic animals, knock-out animals, in silico models, pharmaco-genomics and pharmaco-proteomics, as well as Artificial Intelligence (AI) methods offered new possibilities. - There are several examples, that show that the "druggability" of compounds was considerably underestimated when the probability of success of a new project was assessed. The success rate in the pharmaceutical industry and the introduction of new chemical entities to the market per year dropped dramatically, whereas the development time for a new compound increased, sometimes exceeding the patent protection. Research and development scientists, involving the following changes, therefore adopted a change of strategy: - Parallel instead of sequential involvement of the various disciplines (multidimensional compound optimization). - The term "Safety Pharmacology" was coined. The International Conference on Harmonization (ICH) founded a Safety Pharmacology Working Group and the Safety Pharmacology Society (SPS) was launched. The discipline provided for evaluation, development and validation of a multitude of safety tests outlined in the 'Core Battery of Studies'. - Characterizing the exposure profile of a drug by conducting pharmacokinetic studies that evaluates the absorption, distribution, metabolism and excretion should to be investigated at an early stage of development as results contribute to the selection of a compound for further development. Advancements in Toxicology were achieved by the introduction of new methods, e.g., in silico methods, genetic toxicology, computational toxicology and AI. The book is a landmark in the continuously changing world of drug research and developments. As such, it is essential reading for many groups: not only for all students of pharmacology and toxicology but also for industry scientists and physicians, especially those involved in clinical trials of drugs, and for pharmacists who must know the safety requirements of drugs. The book is essential for scientists and managers in the pharmaceutical industry who are involved in drug discovery, drug development and decision making in the development process. In particular, the book will be of use to government institutions and committees working on official guidelines for drug evaluation worldwide.
Book Synopsis Handbook of Research on Soft Computing and Nature-Inspired Algorithms by : Shandilya, Shishir K.
Download or read book Handbook of Research on Soft Computing and Nature-Inspired Algorithms written by Shandilya, Shishir K. and published by IGI Global. This book was released on 2017-03-10 with total page 649 pages. Available in PDF, EPUB and Kindle. Book excerpt: Soft computing and nature-inspired computing both play a significant role in developing a better understanding to machine learning. When studied together, they can offer new perspectives on the learning process of machines. The Handbook of Research on Soft Computing and Nature-Inspired Algorithms is an essential source for the latest scholarly research on applications of nature-inspired computing and soft computational systems. Featuring comprehensive coverage on a range of topics and perspectives such as swarm intelligence, speech recognition, and electromagnetic problem solving, this publication is ideally designed for students, researchers, scholars, professionals, and practitioners seeking current research on the advanced workings of intelligence in computing systems.
Book Synopsis Practice of Optimisation Theory in Geotechnical Engineering by : Zhen-Yu Yin
Download or read book Practice of Optimisation Theory in Geotechnical Engineering written by Zhen-Yu Yin and published by Springer. This book was released on 2019-04-25 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the development of an optimization platform for geotechnical engineering, which is one of the key components in smart geotechnics. The book discusses the fundamentals of the optimization algorithm with constitutive models of soils. Helping readers easily understand the optimization algorithm applied in geotechnical engineering, this book first introduces the methodology of the optimization-based parameter identification, and then elaborates the principle of three newly developed efficient optimization algorithms, followed by the ideas of a variety of laboratory tests and formulations of constitutive models. Moving on to the application of optimization methods in geotechnical engineering, this book presents an optimization-based parameter identification platform with a practical and concise interface based on the above theories. The book is intended for undergraduate and graduate-level teaching in soil mechanics and geotechnical engineering and other related engineering specialties. It is also of use to industry practitioners, due to the inclusion of real-world applications, opening the door to advanced courses on both modeling and algorithm development within the industrial engineering and operations research fields.
Book Synopsis Foundations of Theoretical Approaches in Systems Biology by : Alberto Marin-Sanguino
Download or read book Foundations of Theoretical Approaches in Systems Biology written by Alberto Marin-Sanguino and published by Frontiers Media SA. This book was released on 2019-01-11 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: If biology in the 20th century was characterized by an explosion of new technologies and experimental methods, that of the 21st has seen an equally exuberant proliferation of mathematical and computational methods that attempt to systematize and explain the abundance of available data. As we live through the consolidation of a new paradigm where experimental data goes hand in hand with computational analysis, we contemplate the challenge of fusing these two aspects of the new biology into a consistent theoretical framework. Whether systems biology will survive as a field or be washed away by the tides of future fads will ultimately depend on its success to achieve this type of synthesis. The famous quote attributed to Kurt Lewin comes to mind: "there is nothing more practical than a good theory". This book presents a wide assortment of articles on systems biology in an attempt to capture the variety of current methods in systems biology and show how they can help to find answers to the challenges of modern biology.
Book Synopsis Handbook of Research on Swarm Intelligence in Engineering by : Bhattacharyya, Siddhartha
Download or read book Handbook of Research on Swarm Intelligence in Engineering written by Bhattacharyya, Siddhartha and published by IGI Global. This book was released on 2015-04-30 with total page 770 pages. Available in PDF, EPUB and Kindle. Book excerpt: Swarm Intelligence has recently emerged as a next-generation methodology belonging to the class of evolutionary computing. As a result, scientists have been able to explain and understand real-life processes and practices that previously remained unexplored. The Handbook of Research on Swarm Intelligence in Engineering presents the latest research being conducted on diverse topics in intelligence technologies such as Swarm Intelligence, Machine Intelligence, Optical Engineering, and Signal Processing with the goal of advancing knowledge and applications in this rapidly evolving field. The enriched interdisciplinary contents of this book will be a subject of interest to the widest forum of faculties, existing research communities, and new research aspirants from a multitude of disciplines and trades.
Book Synopsis Advances in Metaheuristics by : Timothy Ganesan
Download or read book Advances in Metaheuristics written by Timothy Ganesan and published by CRC Press. This book was released on 2016-11-28 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Metaheuristics: Applications in Engineering Systems provides details on current approaches utilized in engineering optimization. It gives a comprehensive background on metaheuristic applications, focusing on main engineering sectors such as energy, process, and materials. It discusses topics such as algorithmic enhancements and performance measurement approaches, and provides insights into the implementation of metaheuristic strategies to multi-objective optimization problems. With this book, readers can learn to solve real-world engineering optimization problems effectively using the appropriate techniques from emerging fields including evolutionary and swarm intelligence, mathematical programming, and multi-objective optimization. The ten chapters of this book are divided into three parts. The first part discusses three industrial applications in the energy sector. The second focusses on process optimization and considers three engineering applications: optimization of a three-phase separator, process plant, and a pre-treatment process. The third and final part of this book covers industrial applications in material engineering, with a particular focus on sand mould-systems. It also includes discussions on the potential improvement of algorithmic characteristics via strategic algorithmic enhancements. This book helps fill the existing gap in literature on the implementation of metaheuristics in engineering applications and real-world engineering systems. It will be an important resource for engineers and decision-makers selecting and implementing metaheuristics to solve specific engineering problems.
Book Synopsis Foundations of Computational Intelligence Volume 3 by : Ajith Abraham
Download or read book Foundations of Computational Intelligence Volume 3 written by Ajith Abraham and published by Springer Science & Business Media. This book was released on 2009-04-27 with total page 531 pages. Available in PDF, EPUB and Kindle. Book excerpt: Global optimization is a branch of applied mathematics and numerical analysis that deals with the task of finding the absolutely best set of admissible conditions to satisfy certain criteria / objective function(s), formulated in mathematical terms. Global optimization includes nonlinear, stochastic and combinatorial programming, multiobjective programming, control, games, geometry, approximation, algorithms for parallel architectures and so on. Due to its wide usage and applications, it has gained the attention of researchers and practitioners from a plethora of scientific domains. Typical practical examples of global optimization applications include: Traveling salesman problem and electrical circuit design (minimize the path length); safety engineering (building and mechanical structures); mathematical problems (Kepler conjecture); Protein structure prediction (minimize the energy function) etc. Global Optimization algorithms may be categorized into several types: Deterministic (example: branch and bound methods), Stochastic optimization (example: simulated annealing). Heuristics and meta-heuristics (example: evolutionary algorithms) etc. Recently there has been a growing interest in combining global and local search strategies to solve more complicated optimization problems. This edited volume comprises 17 chapters, including several overview Chapters, which provides an up-to-date and state-of-the art research covering the theory and algorithms of global optimization. Besides research articles and expository papers on theory and algorithms of global optimization, papers on numerical experiments and on real world applications were also encouraged. The book is divided into 2 main parts.
Book Synopsis Computational Systems Biology of Cancer by : Emmanuel Barillot
Download or read book Computational Systems Biology of Cancer written by Emmanuel Barillot and published by CRC Press. This book was released on 2012-08-25 with total page 461 pages. Available in PDF, EPUB and Kindle. Book excerpt: The future of cancer research and the development of new therapeutic strategies rely on our ability to convert biological and clinical questions into mathematical models-integrating our knowledge of tumour progression mechanisms with the tsunami of information brought by high-throughput technologies such as microarrays and next-generation sequencin
Book Synopsis Fused Deposition Modeling Based 3D Printing by : Harshit K. Dave
Download or read book Fused Deposition Modeling Based 3D Printing written by Harshit K. Dave and published by Springer Nature. This book was released on 2021-04-21 with total page 517 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers 3D printing activities by fused deposition modeling process. The two introductory chapters discuss the principle, types of machines and raw materials, process parameters, defects, design variations and simulation methods. Six chapters are devoted to experimental work related to process improvement, mechanical testing and characterization of the process, followed by three chapters on post-processing of 3D printed components and two chapters addressing sustainability concerns. Seven chapters discuss various applications including composites, external medical devices, drug delivery system, orthotic inserts, watertight components and 4D printing using FDM process. Finally, six chapters are dedicated to the study on modeling and optimization of FDM process using computational models, evolutionary algorithms, machine learning, metaheuristic approaches and optimization of layout and tool path.
Book Synopsis Handbook of Research on Smart Computing for Renewable Energy and Agro-Engineering by : Kharchenko, Valeriy
Download or read book Handbook of Research on Smart Computing for Renewable Energy and Agro-Engineering written by Kharchenko, Valeriy and published by IGI Global. This book was released on 2019-12-06 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: The rise in population and the concurrently growing consumption rate necessitates the evolution of agriculture to adopt current computational technologies to increase production at a faster and smoother scale. While existing technologies may help in crop processing, there is a need for studies that seek to understand how modern approaches like artificial intelligence, fuzzy logic, and hybrid algorithms can aid the agricultural process while utilizing energy sources efficiently. The Handbook of Research on Smart Computing for Renewable Energy and Agro-Engineering is an essential publication that examines the benefits and barriers of implementing computational models to agricultural production and energy sources as well as how these models can produce more cost-effective and sustainable solutions. Featuring coverage on a wide range of topics such as bacterial foraging, swarm intelligence, and combinatorial optimization, this book is ideally designed for agricultural engineers, farmers, municipal union leaders, computer scientists, information technologists, sustainable developers, managers, environmentalists, industry professionals, academicians, researchers, and students.
Book Synopsis Scientific and Technical Aerospace Reports by :
Download or read book Scientific and Technical Aerospace Reports written by and published by . This book was released on 1991 with total page 912 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Secretary's Annual Report to Congress by : United States. Department of Energy
Download or read book Secretary's Annual Report to Congress written by United States. Department of Energy and published by . This book was released on 1987 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt:
