Integrative Neuroscience and Personalized Medicine

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Author :
Publisher : Createspace Independent Publishing Platform
ISBN 13 : 9781723396991
Total Pages : 300 pages
Book Rating : 4.3/5 (969 download)

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Book Synopsis Integrative Neuroscience and Personalized Medicine by : Charlie Graham

Download or read book Integrative Neuroscience and Personalized Medicine written by Charlie Graham and published by Createspace Independent Publishing Platform. This book was released on 2018-03-21 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: The material provide a extensive written text appropriate as both a pithy guide to and a clear conclusion of the "science to solutions" procession in this creating field of Customized Medication and Integrative Neuroscience. The technology contains both actions of genetics using whole genome techniques and SNIPS as well as BRAINmarkers of direct thinking processes such as mind picture, biophysical changes and purpose intellectual and behavior dimensions. Customized Medication for Brain Problems will soon be a reality using the extensive quantitative and consistent ways to genomics, BRAINmarkers and intellectual operate. Each section provides a review of recent appropriate literature; show the alternatives obtained through integrative neuroscience and programs in individual good care thus offering a practical guide to the various readers. The timeliness of this book's content is propitious offering main point here information to inform exercising physicians, medical good care employees and scientists, and also a process for undergrad and graduate students interested in further their understanding of and participation in designed personal alternatives.

Integrative Neuroscience and Personalized Medicine

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Publisher : Oxford University Press
ISBN 13 : 0195393805
Total Pages : 346 pages
Book Rating : 4.1/5 (953 download)

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Book Synopsis Integrative Neuroscience and Personalized Medicine by : Evian Gordon

Download or read book Integrative Neuroscience and Personalized Medicine written by Evian Gordon and published by Oxford University Press. This book was released on 2011 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book takes an in depth and hard look at the current status and future direction of treatment predictive markers in Personalized Medicine for the brain from the perspectives of the researchers on the cutting edge and those involved in healthcare implementation. The contents provide a comprehensive text suitable as both a pithy introduction to and a clear summary of the "science to solutions" continuum in this developing field of Personalized Medicine and Integrative Neuroscience. The science includes both measures of genes using whole genome approaches and SNIPS as well as BRAINmarkers of direct brain function such as brain imaging, biophysical changes and objective cognitive and behavioral measurements. Personalized Medicine for Brain Disorders will soon be a reality using the comprehensive quantitative and standardized approaches to genomics, BRAINmarkers and cognitive function. Each chapter provides a review of recent relevant literature; show the solutions achieved through integrative neuroscience and applications in patient care thus providing a practical guide to the reader. The timeliness of this book's content is propitious providing bottom line information to educate practicing clinicians, health care workers and researchers, and also a pathway for undergraduate and graduates interested in further their understanding of and involvement in tailored personal solutions.

Personalized Medicine in Neuroscience: Molecular to System Approach

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Publisher : Frontiers Media SA
ISBN 13 : 2832541275
Total Pages : 169 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Personalized Medicine in Neuroscience: Molecular to System Approach by : Ali Yadollahpour

Download or read book Personalized Medicine in Neuroscience: Molecular to System Approach written by Ali Yadollahpour and published by Frontiers Media SA. This book was released on 2024-04-17 with total page 169 pages. Available in PDF, EPUB and Kindle. Book excerpt: Personalized or precision medicine (PM) is developing and adopting of the safest and most cost-effective therapeutic approach for each patient. PM approach aims to identify phenotypic and genotypic individual characteristics, observe how these parameters are correlated with the disease status, severity, and intervention responsiveness to predict the best personalized clinical protocol. On the other hand, the risk of severe toxicity and adverse effects might be related to the patient-specific characteristics.

Neurodegenerative Diseases: Integrative PPPM Approach as the Medicine of the Future

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Publisher : Springer Science & Business Media
ISBN 13 : 9400758669
Total Pages : 402 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Neurodegenerative Diseases: Integrative PPPM Approach as the Medicine of the Future by : Silvia Mandel

Download or read book Neurodegenerative Diseases: Integrative PPPM Approach as the Medicine of the Future written by Silvia Mandel and published by Springer Science & Business Media. This book was released on 2013-03-12 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will compile a collection of chapters dedicated to varied aspects of PPPM in neuropsychiatric and neurodegenerative diseases. Among the topics to be covered are: Recent advances in ALS research News about Clinical aspects and advanced therapy approaches in personalized treatment of ALS Schizophrenia: New treatments and clinical aspects Predictive, Preventive and Personalised Medicine in aging macular degeneration Advances in Multiple Sclerosis Pharmacogenetics, Tailoring Treatment Efficacy, Safety and Regimen Selection Multiple sclerosis related biomarkers: perspectives for clinical application Preventive clinical trials in brain aging: new trends & the need of guidelines MCI_ clinical guidelines in early diagnosis of dementia Alzheimer's disease: diagnostics, prognostics and the road to prevention Biomarkers for early diagnosis of Parkinson's and Alzheimer's diseases Synucleinopathies, tauopathies, TDP-43 proteinopathies and amyloidosis PSP, MSA and other parkinsonisms

Translational Medicine in CNS Drug Development

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Publisher : Academic Press
ISBN 13 : 0128031646
Total Pages : 458 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Translational Medicine in CNS Drug Development by : George G. Nomikos

Download or read book Translational Medicine in CNS Drug Development written by George G. Nomikos and published by Academic Press. This book was released on 2019-06-18 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Medicine in CNS Drug Development, Volume 29, is the first book of its kind to offer a comprehensive overview of the latest developments in translational medicine and biomarker techniques. With extensive coverage on all aspects of biomarkers and personalized medicine, and numerous chapters devoted to the best strategies for developing drugs that target specific disorders, this book presents an essential reference for researchers in neuroscience and pharmacology who need the most up-to-date techniques for the successful development of drugs to treat central nervous system disorders. Despite increases in the number of individuals suffering from CNS-related disorders, the development and approval of drugs for their treatment have been hampered by inefficiencies in advancing compounds from preclinical discovery to the clinic. However, in the past decades, game-changing strides have been made in our understanding of the pathophysiology of CNS disorders and the relationship of drug exposure in plasma and CNS to pharmacodynamic measures in both animals and humans. Includes comprehensive coverage of biomarker tools and the role of personalized medicine in CNS drug development Discusses strategies for drug development for a full range of CNS indications, with particular attention to neuropsychiatric and neurocognitive disorders Includes chapters written by international experts from industry and academia

Precision Medicine in Neurodegenerative Disorders

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Author :
Publisher : Elsevier
ISBN 13 : 032390064X
Total Pages : 290 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Precision Medicine in Neurodegenerative Disorders by :

Download or read book Precision Medicine in Neurodegenerative Disorders written by and published by Elsevier. This book was released on 2023-02-14 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Precision Medicine in Neurodegenerative Disorders, Part One, Volume 192 in the Handbook of Clinical Neurology deals with the "Why" in the approach to slow the progression of accelerated brain aging. This volume is intended to provide a scholarly background on the framework, basic science and conceptual pitfalls related to disease-modifying efforts in Parkinson's, Alzheimer's and other neurodegenerative disorders. Among topics covered are different models of precision medicine, the lumping-versus-splitting tension in biomarker development and therapeutics, and the rationale for replacing the convergence of the prevailing autopsy-based nosology of neurodegenerative diseases with the divergence of a systems biology approach to human diseases. Specific chapters are dedicated to the promise of genetic subtypes and the lessons in disease modification offered by the fields of oncology and cystic fibrosis that can be adapted to the field of neurodegeneration. Matching a biology-correcting therapy with those biologically suitable to benefit from such therapy represents the vision and mission of precision medicine, the highest level of personalized medicine. Summarizes theory and research on precision medicine in neurodegenerative disorders Covers basic biology, clinical trials and therapeutics Includes disease mechanisms, genetic subtypes, and more

Psychoneuroimmunology

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Publisher : Springer
ISBN 13 : 3319451111
Total Pages : 139 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Psychoneuroimmunology by : Qing Yan

Download or read book Psychoneuroimmunology written by Qing Yan and published by Springer. This book was released on 2016-10-03 with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of the cutting-edge discoveries and the systems approaches related to the multi-disciplinary field of psychoneuroimmunology (PNI), which may provide the scientific basis for mind-body relationships, and aid in the development of personalized medicine. Specifically, the book focuses on the systems biology studies of complex mechanisms, such as stress and inflammation. There is strong evidence supporting the close relationship between stress, inflammation, and disorders including obesity, cardiovascular disease, diabetes, skin diseases, and sleep disorders. As inflammation is a critical connection among different diseases, further elucidating this connection may contribute to the findings of systemic therapeutic targets. Translational medicine is also addressed, by applying PNI approaches in clinical practice. A major challenge in current bioscience is the translation of basic scientific discoveries into better clinical outcomes. With the understanding of the translational implications of PNI, integrative interventions can be applied to modulate stress responses and to promote healthier behaviors. As an important feature of this book, a broad overview of the PNI-associated integrative interventions is provided. These interventions include nutritional supplements, meditation, and other mind-body strategies. From basic concepts to systems methodologies, from theoretical sources to clinical applications, Psychoneuroimmunology contributes to the understanding and development of PNI toward the establishment of personalized and mind-body medicine.

Integrative Medicine and the Health of the Public

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Author :
Publisher : National Academies Press
ISBN 13 : 030914731X
Total Pages : 245 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Integrative Medicine and the Health of the Public by : Institute of Medicine

Download or read book Integrative Medicine and the Health of the Public written by Institute of Medicine and published by National Academies Press. This book was released on 2009-10-16 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: The last century witnessed dramatic changes in the practice of health care, and coming decades promise advances that were not imaginable even in the relatively recent past. Science and technology continue to offer new insights into disease pathways and treatments, as well as mechanisms of protecting health and preventing disease. Genomics and proteomics are bringing personalized risk assessment, prevention, and treatment options within reach; health information technology is expediting the collection and analysis of large amounts of data that can lead to improved care; and many disciplines are contributing to a broadening understanding of the complex interplay among biology, environment, behavior, and socioeconomic factors that shape health and wellness. On February 25 - 27, 2009, the Institute of Medicine (IOM) convened the Summit on Integrative Medicine and the Health of the Public in Washington, DC. The summit brought together more than 600 scientists, academic leaders, policy experts, health practitioners, advocates, and other participants from many disciplines to examine the practice of integrative medicine, its scientific basis, and its potential for improving health. This publication summarizes the background, presentations, and discussions that occurred during the summit.

Engineering-Medicine

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Publisher : CRC Press
ISBN 13 : 1351012258
Total Pages : 420 pages
Book Rating : 4.3/5 (51 download)

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Book Synopsis Engineering-Medicine by : Lawrence S. Chan

Download or read book Engineering-Medicine written by Lawrence S. Chan and published by CRC Press. This book was released on 2019-05-15 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: This transformative textbook, first of its kind to incorporate engineering principles into medical education and practice, will be a useful tool for physicians, medical students, biomedical engineers, biomedical engineering students, and healthcare executives. The central approach of the proposed textbook is to provide principles of engineering as applied to medicine and guide the medical students and physicians in achieving the goal of solving medical problems by engineering principles and methodologies. For the medical students and physicians, this proposed textbook will train them to “think like an engineer and act as a physician”. The textbook contains a variety of teaching techniques including class lectures, small group discussions, group projects, and individual projects, with the goals of not just helping students and professionals to understand the principles and methods of engineering, but also guiding students and professionals to develop real-life solutions. For the biomedical engineers and biomedical engineering students, this proposed textbook will give them a large framework and global perspective of how engineering principles could positively impact real-life medicine. To the healthcare executives, the goal of this book is to provide them general guidance and specific examples of applying engineering principles in implementing solution-oriented methodology to their healthcare enterprises. Overall goals of this book are to help improve the overall quality and efficiency of healthcare delivery and outcomes.

Pediatricians and Pharmacologically Trained Psychologists

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Publisher : Springer Science & Business Media
ISBN 13 : 1441977805
Total Pages : 317 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Pediatricians and Pharmacologically Trained Psychologists by : George M. Kapalka

Download or read book Pediatricians and Pharmacologically Trained Psychologists written by George M. Kapalka and published by Springer Science & Business Media. This book was released on 2011-01-20 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many factors affect treatment options for children and adolescents with mental health problems, including age, severity of symptoms, financial and time constraints, and access to qualified professionals. With the limitations of managed care plans and the shrinking pool of pediatric psychiatrists, the trend is toward pediatricians prescribing psychotropic medicines. Pharmacologically trained psychologists can offer valuable assistance to pediatricians caught in this predicament. Tackling fundamental questions of when to treat as well as when and why to refer young patients, the Pediatricians and Pharmacologically Trained Psychologists examines commonly occurring pediatric conditions requiring joint treatment; reviews theoretical models of consultation and collaboration; and spotlights professional issues typically arising from these team efforts. With pertinent clarity and detail, this volume offers in-depth discussion in these key areas: Collaborative treatment of mental health conditions, including mood, disruptive, anxiety, and eating disorders. Collaborative treatment of medical conditions, focusing on gastrointestinal disorders and diabetes. Changing clinical procedures in states that have enacted prescriptive authority for psychologists. Expanding roles for pharmacologically trained psychologists practicing in states that have not enacted prescriptive authority for psychologists. Medical psychology in the pediatric hospital. Integrative care in rural settings and on the reservation. The collaborative future: brain marker technology, training paradigms, and more. Pediatricians and Pharmacologically Trained Psychologists is a must-have reference for a broad range of researchers, professionals, and graduate students, including psychologists, pediatricians and other child mental health clinicians as well as nonphysician prescribers, such as nurses, physician assistants, and pharmacists.

The Road from Nanomedicine to Precision Medicine

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Publisher : CRC Press
ISBN 13 : 1000043320
Total Pages : 646 pages
Book Rating : 4.0/5 ( download)

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Book Synopsis The Road from Nanomedicine to Precision Medicine by : Shaker. A Mousa

Download or read book The Road from Nanomedicine to Precision Medicine written by Shaker. A Mousa and published by CRC Press. This book was released on 2020-01-06 with total page 646 pages. Available in PDF, EPUB and Kindle. Book excerpt: The enormous advances in nanomedicine and precision medicine in the past two decades necessitated this comprehensive reference, which can be relied upon by researchers, clinicians, pharmaceutical scientists, regulators, policymakers, and lawyers alike. This standalone, full-color resource broadly surveys innovative technologies and advances pertaining to nanomedicine and precision medicine. In addition, it addresses often-neglected yet crucial areas such as translational medicine, intellectual property law, ethics, policy, FDA regulatory issues, nano-nomenclature, and artificial nano-machines—all accomplished in a user-friendly, broad yet interconnected format. The book is essential reading for the novice and the expert alike in diverse fields such as medicine, law, pharmacy, genomics, biomedical sciences, ethics, and regulatory science. The book’s multidisciplinary approach will attract a global audience and serve as a valuable reference resource for industry, academia, and government.

Integrative Neuroscience

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Publisher : CRC Press
ISBN 13 : 0203304764
Total Pages : 269 pages
Book Rating : 4.2/5 (33 download)

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Book Synopsis Integrative Neuroscience by : Evian Gordon

Download or read book Integrative Neuroscience written by Evian Gordon and published by CRC Press. This book was released on 2003-09-02 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most brain related activity has focussed on specialized interests within individual disciplines. Recent multidisciplinary activity has provided the impetus to break down these boundaries and encourage a freer exchange of information across disciplines. This text reflects these developments. It spans the landscape of brain science to provide core information from 12 disciplines (including evolution, philosophy, anatomy, chemistry, computer science, brain dynamics, psychology, neurology, psychiatry, psychotherapy and brain imaging). In outlining how and why it is now possible to realistically model aspects of the brain's dynamics from such a wide range of intellectual endeavors, this book will prove itself useful to undergraduates, postgraduates and all those seeking a contemporary perspective and evaluation of the current status and future directions in the brain sciences.

Precision Medicine in Neurodegenerative Disorders

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Author :
Publisher : Elsevier
ISBN 13 : 0323900658
Total Pages : 394 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Precision Medicine in Neurodegenerative Disorders by :

Download or read book Precision Medicine in Neurodegenerative Disorders written by and published by Elsevier. This book was released on 2023-02-16 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: Precision Medicine in Neurodegenerative Disorders, Part Two, Volume 193 in the Handbook of Clinical Neurology deals with the "How" in the reconfiguration of our approach to slow accelerated brain aging. The book rethinks animal models on which therapies are tested, outlines the progress and expected changes in biological subtyping efforts using lysosomal, endosomal, mitochondrial, immune dysregulation, and inflammatory mechanisms of disease pathophysiology, and the growing role of microbiome in shaping disease. The volume separates the potentially disease-modifying neurorescue and neurorestoration, (e.g., gene therapy and cell replacement therapy) from true precision "medicine"–matching biology with the mechanism of intervention of interest. Specific chapters are dedicated to the promise and challenges of extracellular vesicles for both diagnosis and treatment, the growing application of digital measures and other evaluations of clinical response, the nuts and bolts of novel adaptive clinical trial designs, and the regulatory changes needed to facilitate drug development for disease-modification purposes. Summarizes theory and research on precision medicine in neurodegenerative disorders Covers basic biology, clinical trials and therapeutics Includes disease mechanisms, genetic subtypes, and more

Middleton's Allergy E-Book

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 0323546986
Total Pages : 1840 pages
Book Rating : 4.3/5 (235 download)

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Book Synopsis Middleton's Allergy E-Book by : A Wesley Burks

Download or read book Middleton's Allergy E-Book written by A Wesley Burks and published by Elsevier Health Sciences. This book was released on 2019-09-25 with total page 1840 pages. Available in PDF, EPUB and Kindle. Book excerpt: Through eight outstanding editions, Middleton’s Allergy: Principles and Practice has been the reference of choice for both clinicians and researchers as both a practical reference and an effective self-assessment tool for board preparation. The 9th Edition continues the tradition of excellence with comprehensive coverage of all basic science and clinical applications regarding allergy practice and disease mechanisms. It brings you fully up to date with recent innovations in the diagnosis, prevention, and management of allergic disorders, including emerging global issues, the advent of precision medicine, and new immunologic therapies. Offers unparalleled depth and up-to-date guidance on the full spectrum of allergy across the lifespan, with significant updates throughout. Contains new chapters on Innate Lymphoid Cells, Systems Biology, and Treatment of Primary Immunodeficiency Diseases. Discusses emerging topics such as epidemic thunderstorm asthma and precision medicine in allergic disorders. Features more than 730 full-color illustrations, including many new cellular and molecular drawings of disease mechanisms. Includes new Summary of Important Concepts boxes, plus new multiple-choice questions online with explanations and answers. Features a new team of expert editors and more international contributors for a global perspective of this complex field.

Kaplan and Sadock's Synopsis of Psychiatry: Behavioral Sciences/Clinical Psychiatry

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Author :
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1469883759
Total Pages : 3403 pages
Book Rating : 4.4/5 (698 download)

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Book Synopsis Kaplan and Sadock's Synopsis of Psychiatry: Behavioral Sciences/Clinical Psychiatry by : Benjamin J. Sadock

Download or read book Kaplan and Sadock's Synopsis of Psychiatry: Behavioral Sciences/Clinical Psychiatry written by Benjamin J. Sadock and published by Lippincott Williams & Wilkins. This book was released on 2014-09-22 with total page 3403 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synopsis of Psychiatry: Behavorial Sciences/Clinical Psychiatry, 11th Edition is the only authoritative textbook for clinicians, residents, and students covering all psychiatric conditions. It is a complete, concise overview of the entire field of psychiatry, for psychiatrists in training and practice and all others who study and provide mental health care. Its multidisciplinary approach encompasses the biological, psychological and sociological factors at work in health and disease. The latest information about specific diseases, psychopharmacotherapeutic and behavioral treatments and scientific research is incorporated into this revision. ICD (International Classification of Disease, World Health Organization) diagnostic criteria and numerical codes, used for reimbursement purposes, are included. Case studies throughout reinforce the clinical relevance of specific topics. The 11th edition is set apart from any other reference you have: • Contains DSM5 tables on every major psychiatric disorder • Use it to supplement the DSM5, offering current diagnostic and treatment protocols • Over 50 years of compounded knowledge in psychiatric medicine, offered by world-renowned experts

Personalized and Precision Integrative Cardiovascular Medicine

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Author :
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1975115295
Total Pages : 1201 pages
Book Rating : 4.9/5 (751 download)

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Book Synopsis Personalized and Precision Integrative Cardiovascular Medicine by : Mark Houston

Download or read book Personalized and Precision Integrative Cardiovascular Medicine written by Mark Houston and published by Lippincott Williams & Wilkins. This book was released on 2019-10-08 with total page 1201 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encompassing functional cardiology, integrative medicine, and metabolic medicine/cardiology, this unique reference offers an up-to-date, expert approach to heart health wellness and treating the diseased heart and blood vessels. It provides today’s practitioners with insight into various treatment options and alternatives to pharmaceutical care and surgery, incorporating new scientific information on metabolic and integrative cardiovascular medicine from peer-reviewed articles, evidence-based medicine, and human clinical research as a foundation for practical clinical information.

Preserving Brain Health in a Toxic Age

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Author :
Publisher : Rowman & Littlefield
ISBN 13 : 1538158086
Total Pages : 281 pages
Book Rating : 4.5/5 (381 download)

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Book Synopsis Preserving Brain Health in a Toxic Age by : Arnold R. Eiser

Download or read book Preserving Brain Health in a Toxic Age written by Arnold R. Eiser and published by Rowman & Littlefield. This book was released on 2021-10-11 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn how to reduce the impact of environmental toxins on brain development, functioning, and health. The human brain is a marvelously complex organ that has evolved great new capabilities over the past 250,000 years. During most of that period, daily life was vastly different from our lives today. Exercise was not optional - one literally had to run for one’s life, livelihood, and sustenance. The Stone Age diet was not a fad, but the only food available. Periods of fasting arose from food scarcity, and hence the earliest keto-diet was commonplace. Life changed greatly with the advent of agriculture and industry. Diseases that were previously unknown or uncommon began to surface as by-products of civilization’s advance. Changes in our ways of living have altered the nature of illness as well as its diagnosis and treatment. From the 1970s to the present, tens of thousands of chemicals with applications in all aspects of our lives have grown more than 40-fold. Exposure to these new substances has impacted many aspects of our health, especially the delicate parts of the brain and nervous system. In parallel with the changes in our environment, we have seen the growth of brain disorders including Alzheimer’s Disease and autism in previously unimaginable ways. Here, Arnold Eiser elucidates some features of diseases affecting the nervous system that are increasing in incidence with a focus on those disorders that appear related to environmental toxins that modern life has introduced. He takes readers behind the scenes of the science itself to discover the human stories involved in the discovery and management of these illnesses. Offering insights from a variety of scientific disciplines, Eiser clearly and succinctly illustrates the impact of toxins on our brains and how we might better protect ourselves from negative outcomes. With interviews from leading authorities in the field of neuroscience, environmental toxicology, integrative medicine, neurology, immunology, geriatrics, and microbiology (re the gut microbiome), this book offers a robust understanding of the complex threats to our brains, and the healthy brain’s dependence upon many other systems within our bodies. This is a voyage of discovery into the science, history, and human struggle regarding disorders challenging the brain as well as their possible prevention.