Insulin Resistance - ECAB

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Publisher : Elsevier Health Sciences
ISBN 13 : 8131232212
Total Pages : 131 pages
Book Rating : 4.1/5 (312 download)

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Book Synopsis Insulin Resistance - ECAB by : Gita Ganguly Mukherjee

Download or read book Insulin Resistance - ECAB written by Gita Ganguly Mukherjee and published by Elsevier Health Sciences. This book was released on 2010-10-26 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt: The insulin resistance syndrome can be defined as insulin resistance, compensatory hyperinsulinemia, and their associated co-morbidities. Clinically, the term insulin resistance syndrome describes a constellation of abnormalities such as obesity, hypertension, dyslipidemia, type 2 diabetes/hyperglycemia, and coronary artery disease. Insulin is responsible for glucose uptake into the body cells and tissues. The response of the cells to insulin varies from individual to individual. In some individuals, the tissue response to insulin may be diminished. This means that even with adequate levels of insulin, the glucose uptake into the cells and tissues is not optimal. This results in a compensatory over-secretion of insulin from the pancreas. The persistence of high levels of insulin in the blood or hyperinsulinemia is thought to be responsible for some of the abnormalities associated with this condition. However, the exact causal association of the condition with these disorders and the pathophysiology of their evolution are unclear. The most common underlying mechanism proposed is increased free fatty acids from abdominal fat in individuals with central obesity. This leads to deranged insulin signaling, reduced muscular glucose uptake, increased triglyceride synthesis, and hepatic gluconeogenesis. A genetic basis of the disease as well as several other factors such as tumor necrosis factor-a, adiponectin, leptin, Interleukin-6, and some adipokines have also been implicated. Insulin resistance syndrome is of clinical significance because of its association with potentially debilitating conditions that contribute to long-term morbidity and even mortality of the individual. People with insulin resistance syndrome are at an increased risk of developing type 2 diabetes, hypertension, dyslipidemia, myocardial infarction, polycystic ovarian disease, and fatty liver. In this book, we have tried to collate the experiences of the pioneers of this field on the subject and provide the reader a comprehensive view on the topic along with practical management points, which we are sure will benefit the physicians in their clinical practice. The contributors have focused on the condition as is prevalent in our subcontinent and have tried to give an insight on the issues pertaining to the same with a topical flavor.

Hotspots in Diabetes - ECAB

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Publisher : Elsevier Health Sciences
ISBN 13 : 8131232174
Total Pages : 129 pages
Book Rating : 4.1/5 (312 download)

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Book Synopsis Hotspots in Diabetes - ECAB by : Ambady Ramachandran

Download or read book Hotspots in Diabetes - ECAB written by Ambady Ramachandran and published by Elsevier Health Sciences. This book was released on 2013-07-12 with total page 129 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes is one of the most important non-communicable lifestyle diseases. Diabetes is a multifaceted disorder which possibly influences and impacts body pathophysiology by different mechanisms and in varied ways. Diabetes has a very distinguished impact on cardiovascular system and plays a detrimental role in development of cardiovascular disorders. Metabolic memory is used to describe the impact of exposure to glucotoxicity, lipotoxicity and other metabolic disturbances, either as an adverse or a beneficial cell response which determines the later development of vascular complications. Terms such as metabolic imprint, legacy effect, glycemic memory or latent hyperglycemic damage are also used. Diabetes has significant impact on different facets of life. Diabetes has a distinguished but significant impact on development of various cancers. Diabetes has a positive, negative and even neutral impact on pathogenesis and progression of cancer depending upon the tumor site. On the contrary, cancer also has a significant effect on diabetes development and management. These facets tend to get overlooked in the study of diabetes development and management. All these aspects are being thoroughly covered in this project so as to facilitate better management of diabetics.

Cardiometabolic Risk in India - ECAB

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Publisher : Elsevier Health Sciences
ISBN 13 : 8131232107
Total Pages : 120 pages
Book Rating : 4.1/5 (312 download)

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Book Synopsis Cardiometabolic Risk in India - ECAB by : KM Prasanna Kumar

Download or read book Cardiometabolic Risk in India - ECAB written by KM Prasanna Kumar and published by Elsevier Health Sciences. This book was released on 2009-02-15 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiometabolic disease is the leading cause of death in many parts of the world. There are many potentially modifiable and non-modifiable risk factors associated with the same. Although with the recent advances in management and preventive strategies the mortality rates have reduced, but no patient actually achieves an adequate control of the CVD risk factors with the declining quality of life. In addition, growing obesity and DM in younger age groups has further undermined the improvements achieved in CVD. Diabetes and CVD share a "common soil" in their etiology and the causative factors for these diseases are termed as "cardiometabolic risk factors." Cardiometabolic risk (CMR) is the global risk of developing type 2 diabetes and CVD. CMR factors include overweight or obesity, high blood glucose, HTN, dyslipidemia, inflammation and hypercoagulation, physical inactivity, smoking, age, race and ethnicity, gender, and family history. Among these, age, race/ethnicity, gender, and family history are non-modifiable risk factors. The remaining are modifiable risk factors and closely interrelated. Recently, systematic prospective studies have shown evidences that moderate lifestyle modifications help in reducing the metabolic risk factors. The major principles include cessation of smoking, enhanced physical activity, and reduction of excess weight. Healthy diet also has a major role in controlling overweight and maintaining ideal weight. Each of the risk factors poses a danger to good health; the propensity increases with multiple risk factors. It is also shown that the CMR factors tend to cluster as the metabolic syndrome. This book is designed to address such questions with supportive typical clinical scenarios, with which all readers will be able to identify. Thus it provides an excellent opportunity to widen one’s perspective in this area.

Polycystic Ovary Syndrome - ECAB

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Publisher : Elsevier Health Sciences
ISBN 13 : 8131232220
Total Pages : 159 pages
Book Rating : 4.1/5 (312 download)

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Book Synopsis Polycystic Ovary Syndrome - ECAB by : Gita Ganguly Mukherjee

Download or read book Polycystic Ovary Syndrome - ECAB written by Gita Ganguly Mukherjee and published by Elsevier Health Sciences. This book was released on 2012-07-05 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt: PCOS is a complex endocrinopathy with wide-ranging variations and clinical manifestations. In the field of gynecology, the clinician is called upon to treat problems of menstrual irregularity, acne and hirsutism, infertility, obesity, and for education on long-term consequences. The mainstay of pharmacological treatment aims at ovarian suppression of androgen secretion. The most effective medical therapy for hirsutism in these cases thus appears to be antiandrogen drugs. The patients need to undergo the therapies for long periods and also understand the need of maintenance. Electrolysis and laser photothermolysis are considered the most effective cosmetic procedures. PCOS is a heterogeneous disorder and no single etiological factor fully accounts for the whole spectrum of the abnormalities in this condition. Only a few genes and mutations show considerable evidence of association with PCOS. Variable manifestation observed within PCOS patients may be due to the interaction with environmental factors with protective genomic variant and predisposing genes. The eminent authors of "Polycystic Ovary Syndrome" have enumerated the various options available described in detail their experiences regarding the various aspects of the condition.

Unconventional Organ Damage in Diabetes - ECAB

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Publisher : Elsevier Health Sciences
ISBN 13 : 813123214X
Total Pages : 112 pages
Book Rating : 4.1/5 (312 download)

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Book Synopsis Unconventional Organ Damage in Diabetes - ECAB by : Samar Banerjee

Download or read book Unconventional Organ Damage in Diabetes - ECAB written by Samar Banerjee and published by Elsevier Health Sciences. This book was released on 2012-09-14 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell health depends on a steady supply of fuel from glucose and free fatty acids. Both these major fuels are regulated by insulin. Cells in the muscle, liver, and fat need insulin to receive glucose, and hence do not become exposed to high blood glucose levels when the blood sugars are high and insulin levels are low. The lack of insulin slows the movement of glucose into these cells, and probably spares them from damage when blood sugars are high. However, other cells such as those in the brain, nervous system, heart, blood vessels and kidneys pick up glucose directly from the blood without using insulin. These cells, except the brain, are more prone to damage from high blood sugars because they become exposed to high internal levels of glucose. This to quite an extent explains why damage tends to occur in specific organs such as in nerve and kidney cells, and in small blood vessels like those in the eyes. This project on the organ damage in diabetes is an attempt to elaborate on the various factors to be considered in managing these patients, the pointers for early diagnosis and prevention of the same.

Recent Advances in Metabolic Syndrome – I - ECAB

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Publisher : Elsevier Health Sciences
ISBN 13 : 8131232182
Total Pages : 207 pages
Book Rating : 4.1/5 (312 download)

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Book Synopsis Recent Advances in Metabolic Syndrome – I - ECAB by : R R Kasliwal

Download or read book Recent Advances in Metabolic Syndrome – I - ECAB written by R R Kasliwal and published by Elsevier Health Sciences. This book was released on 2012-06-08 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt: India in particular and South-Asia in general have witnessed a rapid increase in the prevalence and incidence of cardiovascular disease over the past 25 years. Lifestyles changes, unhealthy diet, lack of regular physical exercise, and obesity have all led to rising prevalence of metabolic syndrome. It is of no wonder that metabolic syndrome is being increasingly recognized as a clinical entity which is believed to be associated with increased risk of cardiovascular disease beyond individual risk factors, though this is at times debated. This monograph addresses the total nuance of metabolic syndrome in its entirety and answers questions frequently asked on this subject. The authors are internationally respected investigators in their own right having made major contributions in the particular field and are revered teachers as well. The book itself has clear sections which makes it very user friendly and divided into two volumes. The first volume has the evaluation of metabolic syndrome and the vastness of the problem and how it leads to smouldering dysfunctional endothelium making such a patient vulnerable to vascular disease. It purely deals with clinical issues we face daily in metabolic syndrome and patients. It is fairly broad-based to answer most of the queries which arise in a busy clinician’s head while dealing with metabolic syndrome on a day-to-day basis. Of special interest are chapters on metabolic syndrome in children, non-alcoholic fatty liver disease and hypogonadism.

Non-Alcoholic Fatty Liver Disease - ECAB

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Publisher : Elsevier Health Sciences
ISBN 13 : 8131231909
Total Pages : 142 pages
Book Rating : 4.1/5 (312 download)

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Book Synopsis Non-Alcoholic Fatty Liver Disease - ECAB by : Sudeep Khanna

Download or read book Non-Alcoholic Fatty Liver Disease - ECAB written by Sudeep Khanna and published by Elsevier Health Sciences. This book was released on 2013-04-15 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: Non-alcoholic fatty liver disease is a common cause of chronic liver disease, and its incidence is rising worldwide. Understanding its pathogenesis, biochemical parameters, histological grading and staging, and its management is a vital issue in today’s clinical practice. It appears to be linked directly to the growing epidemic of obesity in adults as well as in children. Thus, in a sense, NAFLD is a self-inflicted liver disease, much like alcoholic liver disease. The exact causes responsible for the development of NAFLD have not been established yet. However, some researchers consider that cluster of disorders that increases the risk of developing heart disease, diabetes, and stroke may be the factor behind development of NAFLD. Most patients with NAFLD have no symptoms or signs of liver disease at the time of diagnosis. In these patients, abnormal liver function tests are often discovered incidentally. Non-alcoholic steatohepatitis (NASH) is that stage of the spectrum that involves fat accumulation (steatosis), inflammation (hepatitis), and scarring (fibrosis) in the liver. Those who have fatty liver or hepatic steatosis with non-specific inflammation as fatty liver with non-specific inflammation generally have a benign longterm prognosis, whereas those who have NASH can progress to cirrhosis. NASH-related cirrhosis may have similar prognosis as cirrhosis from other causes. Hepatocellular carcinoma (HCC) is part of the spectrum of NAFLD, and screening for HCC seems reasonable in patients who have NASH-related cirrhosis. No established treatment is available for NAFLD. Some empiric treatment strategies have been suggested. Presumably, weight loss through exercise and diet modification along with insulinsensitizing agents will help reverse fatty infiltration of the liver. Its incidence is reportedly on the rise the world over as well as in India. Realizing its significance, there is now greater understanding of its etiology, pathogenesis, and management. The efforts of Elsevier have been directed toward addressing these aspects. Elsevier has thus pooled its existing resources with those of the internationally acclaimed Gastroenterologists of India who have chosen to share their rich clinical knowledge, experience, and expertize to serve the practitioners and patient community.

Recent Advances in Metabolic Syndrome – II - ECAB

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Publisher : Elsevier Health Sciences
ISBN 13 : 8131232190
Total Pages : 136 pages
Book Rating : 4.1/5 (312 download)

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Book Synopsis Recent Advances in Metabolic Syndrome – II - ECAB by : R R Kasliwal

Download or read book Recent Advances in Metabolic Syndrome – II - ECAB written by R R Kasliwal and published by Elsevier Health Sciences. This book was released on 2012-06-11 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt: India in particular and South-Asia in general have witnessed a rapid increase in the prevalence and incidence of cardiovascular disease over the past 25 years. Lifestyles changes, unhealthy diet, lack of regular physical exercise, and obesity have all led to rising prevalence of metabolic syndrome. It is of no wonder that metabolic syndrome is being increasingly recognized as a clinical entity which is believed to be associated with increased risk of cardiovascular disease beyond individual risk factors, though this is at times debated. This monograph addresses the total nuance of metabolic syndrome in its entirety and answers questions frequently asked on this subject. The authors are internationally respected investigators in their own right having made major contributions in the particular field and are revered teachers as well. The book itself has clear sections which makes it very user friendly and divided into two volumes. The book rightfully deals with management of the syndrome and lays emphases not only on lifestyle measures (which are a cornerstone) but also judicious use of pharmacotherapy and also surgical techniques currently in use.

ECAB Non-alcoholic Fatty Liver Disease - E-Book

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Publisher : Elsevier Health Sciences
ISBN 13 : 8131239594
Total Pages : 102 pages
Book Rating : 4.1/5 (312 download)

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Book Synopsis ECAB Non-alcoholic Fatty Liver Disease - E-Book by : Gourdas Choudhuri

Download or read book ECAB Non-alcoholic Fatty Liver Disease - E-Book written by Gourdas Choudhuri and published by Elsevier Health Sciences. This book was released on 2013-01-31 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt: ECAB Non-alcoholic Fatty Liver Disease - E-Book

Critical Issues and Diabetes - ECAB - E-Book

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Publisher : Elsevier Health Sciences
ISBN 13 : 8131239241
Total Pages : 124 pages
Book Rating : 4.1/5 (312 download)

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Book Synopsis Critical Issues and Diabetes - ECAB - E-Book by : Samar Banerjee

Download or read book Critical Issues and Diabetes - ECAB - E-Book written by Samar Banerjee and published by Elsevier Health Sciences. This book was released on 2014-12-12 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt: Critical Issues and Diabetes - ECAB - E-Book

Lipids in Diabetes - ECAB

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Publisher : Elsevier Health Sciences
ISBN 13 : 8131232131
Total Pages : 134 pages
Book Rating : 4.1/5 (312 download)

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Book Synopsis Lipids in Diabetes - ECAB by : S V Madhu

Download or read book Lipids in Diabetes - ECAB written by S V Madhu and published by Elsevier Health Sciences. This book was released on 2013-07-23 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: Type 2 diabetes mellitus is associated with a greater risk of developing atherosclerotic macrovascular diseases like myocardial infarction, stroke, and peripheral vascular disease. There is 2- to 4-fold increased risk of atherosclerotic heart disease and stroke in diabetic patients compared to non-diabetic patients. As the prevalence of type 2 diabetes is increasing rapidly, this diabetes related atherosclerotic disease is predicted to be a major public health problem. Atherosclerosis is a complex process and in diabetic patients, it behaves differently with increased lesion progression and severity. This accelerated atherosclerotic process in diabetics is explained on the basis of several risk factors like hyperglycemia, dyslipidemia, accelerated formation of advanced glycation end products, increased oxidative stress, and genetic factors. It is difficult to establish precisely the elements responsible for this atherosclerosis in diabetics, but by epidemiological, clinical, and by animal studies, it has been possible to get an idea of this problem in diabetics. Of the several risk factors for atherosclerosis in diabetes, dyslipidemia is the leading one, and an insight into the pathophysiologic relation of isolated triglyceridemia in Indian diabetics with the identification of the targets for control of lipids in diabetes (practical vs. ideal) needs to be well understood by the treating physician. This book is designed to address such issues with supportive typical clinical scenarios, with which the readers will be able to identify. Thus, it provides an excellent opportunity to widen one’s perspective in this area.

End Stage Renal Disease - ECAB

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Publisher : Elsevier Health Sciences
ISBN 13 : 8131232018
Total Pages : 205 pages
Book Rating : 4.1/5 (312 download)

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Book Synopsis End Stage Renal Disease - ECAB by : Ravi Raju Tatapudi

Download or read book End Stage Renal Disease - ECAB written by Ravi Raju Tatapudi and published by Elsevier Health Sciences. This book was released on 2013-07-16 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the increase in lifestyle-related diseases like diabetes and hypertension the prevalence of Chronic Kidney Disease (CKD) is increasing exponentially and with it is increasing the burden of its ominous consequence, End Stage Renal Disease (ESRD). While ESRD is no longer a death sentence with the advent of efficient renal replacement therapies and the success of renal transplantation, factors such as high cost of these procedures, limited availability of donated kidneys and not enough number of centers equipped with these facilities puts the effective management of ESRD beyond the reach of an average person many-a-times. Additionally the presence of co-existing diseases that contribute to and sometimes complicate the renal impairment as well as delayed referral of the patients to nephrologists also makes matters worse. ESRD is not just a medical but also a social and economic condition that devastates the person and his/her entire family. Hence, early detection and effective prevention of progression of CKD in early stages to advanced CKD and ESRD is the call of the day. In fact, understanding the pathophysiology of the condition and adopting methods of primordial prevention in populations at risk may be desirable to ensure reduction in the incidence of CKD. In those with established CKD, a proactive approach to manage the disease manifestations and limit the ravages of other comorbidities is desirable. For those in advanced stages of CKD, the institution of an appropriate renal replacement therapy individually suited to the patient keeping in view the medical status, lifestyle requirements, economic viability and social acceptability should be advised. This book will help the reader understand the intricacies of the aspects mentioned above and guide the practitioner to diagnose and manage End Stage Renal Disease with special reference to practical experience of the same in India. The authors have put together the most relevant facts about the disease for an easy comprehension and understanding of the same by practitioners and students across the specialty.

ECAB clinical update Diabetology Mar-April Issue2

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Publisher : Elsevier India
ISBN 13 :
Total Pages : 113 pages
Book Rating : 4.0/5 (465 download)

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Book Synopsis ECAB clinical update Diabetology Mar-April Issue2 by : Dr. Zargar

Download or read book ECAB clinical update Diabetology Mar-April Issue2 written by Dr. Zargar and published by Elsevier India. This book was released on with total page 113 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Oral Hypoglycemic Agents - ECAB

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Publisher : Elsevier Health Sciences
ISBN 13 : 8131232166
Total Pages : 111 pages
Book Rating : 4.1/5 (312 download)

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Book Synopsis Oral Hypoglycemic Agents - ECAB by : Abdul Hamid Zargar

Download or read book Oral Hypoglycemic Agents - ECAB written by Abdul Hamid Zargar and published by Elsevier Health Sciences. This book was released on 2009-09-25 with total page 111 pages. Available in PDF, EPUB and Kindle. Book excerpt: Even though we have many advances in the development of oral hypoglycemic agents, an ideal drug for treating type 2 diabetes is still a distant reality. Today, physicians can choose from a variety of medications targeting numerous facets of disease, but each drug class poses some limitations. The age-old molecules, such as sulfonylureas and biguanides, are still valued because of their well-studied mode of action, safety, tolerability, and predictable pharmacodynamic effects. This book attempts to describe the historical aspects and advances in the arena of oral hypoglycemic agents, extended- and sustained-release formulations of glipizide and metformin (both of which have great promise in the treatment of type 2 diabetes mellitus) as well as evaluates the role of the group in diabetic foot infections.

Medical Disorders in Pregnancy - ECAB

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Publisher : Elsevier Health Sciences
ISBN 13 : 8131232271
Total Pages : 194 pages
Book Rating : 4.1/5 (312 download)

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Book Synopsis Medical Disorders in Pregnancy - ECAB by : Hema Divakar

Download or read book Medical Disorders in Pregnancy - ECAB written by Hema Divakar and published by Elsevier Health Sciences. This book was released on 2009-11-15 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: The management of medical disorders in pregnancy has undergone significant changes in the recent years. The pattern of disease has changed with improvements in socio-economic conditions. For example, the incidence of antenatal anemia has decreased progressively in the past few decades, and pulmonary tuberculosis (which used to be prevalent) is now seen only rarely. Chronic rheumatic heart disease has also become less common. On the other hand, gestational diabetes has become more common. This may be due partly to the setting up of screening services for gestational diabetes in many hospitals. The four most common medical disorders complicating pregnancy are anemia, diabetes mellitus, cardiac disease, and thyroid disorders. In addition, because of the improvements in the medical, obstetric, and anesthetic management of pregnancy, many women with medical disorders can go through a pregnancy without major problems. There has also been a progressive decrease in the perinatal mortality associated with some medical disorders, such as diabetes. It is important for all healthcare professionals involved in the management of pregnant women with medical disorders to be conversant with the latest developments in order to provide the best care to these women. The chapters in this issue are certainly helpful in this respect. The eminent authors for the various chapters have discussed the various options available describing in detail their experiences regarding the various aspects of the condition.

ECAB Probiotics in Prevention of Lifestyle Disorders - E-Book

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 8131239667
Total Pages : 133 pages
Book Rating : 4.1/5 (312 download)

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Book Synopsis ECAB Probiotics in Prevention of Lifestyle Disorders - E-Book by : B S Ramakrishna

Download or read book ECAB Probiotics in Prevention of Lifestyle Disorders - E-Book written by B S Ramakrishna and published by Elsevier Health Sciences. This book was released on 2014-12-11 with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt: ECAB Probiotics in Prevention of Lifestyle Disorders - E-Book

Microvascular Disorders In Diabetes

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Publisher : Elsevier Health Sciences
ISBN 13 : 8131221725
Total Pages : 147 pages
Book Rating : 4.1/5 (312 download)

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Book Synopsis Microvascular Disorders In Diabetes by : Seshiah

Download or read book Microvascular Disorders In Diabetes written by Seshiah and published by Elsevier Health Sciences. This book was released on 2009 with total page 147 pages. Available in PDF, EPUB and Kindle. Book excerpt: