Insulin In Clinical Practice

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Human Insulin

Author : D.R. Owens
Publisher : Springer Science & Business Media
ISBN 13 : 9780852009512
Total Pages : 318 pages
Book Rating : 4.0/5 (95 download)

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Book Synopsis Human Insulin by : D.R. Owens

Download or read book Human Insulin written by D.R. Owens and published by Springer Science & Business Media. This book was released on 1986-05-31 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since insulin became available for the treatment of diabetes in 1922 a number of major advances have been made, which include the modification of insulin to vary its timing of action, its purification, and latterly, the production of human insulin. Human insulin in quantities sufficiently large for therapy has been made available by two techniques developed in parallel during the late 1970s. These involve either (i) formulation in E. coli bacteria suitably encoded by DNA recombinant methods of the A- and B-chains of human insulin followed by a chain combination reaction ('biosynthetic' human insulin) or (ii) enzymatic conversion (transpeptidation) of porcine insulin brought to react with a threonine ester by porcine trypsin in a mixture of water and organic solvents, yielding human insulin ('semi-synthetic' human insulin). This book includes the first clinical-pharmacological studies of each of the highly purified 'semi-synthetic' human insulin preparations: Actrapid ® HM; Monotard® HM; Protaphane® HM; Actraphane® HM; and Ultratard® HM (Novo Industri A/S, Copenhagen). The preliminary studies established their safety and efficacy relative to their porcine and bovine counterparts emphasising the relevance of species and formulation on the pharmacokinetics and biological responses to insulin. Additional investigations with human insulin demonstrated the influence of insulin concentration, site of administration, the addition of aprotinin to insulin and the mixing of 'short-' and 'intermediate-acting' formulations on insulin 'bioavailability'. Examination of the 'within' and 'between' subject day-to-day variation in absorption and the effect of subcutaneous insulin also demonstrates the dominating influence of insulin responsiveness.

Insulin Action

Author : Ashok K. Srivastava
Publisher : Springer Science & Business Media
ISBN 13 : 9780792381136
Total Pages : 206 pages
Book Rating : 4.3/5 (811 download)

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Book Synopsis Insulin Action by : Ashok K. Srivastava

Download or read book Insulin Action written by Ashok K. Srivastava and published by Springer Science & Business Media. This book was released on 1998-05-31 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1996 the 75th anniversary of the discovery of insulin was celebrated at the University of Toronto, the scene of that discovery in 1921. This volume was stimulated by the scientific program which was staged at that time and brought together much of the world's best talent to discuss and analyze the most recent developments in our understanding of pancreatic function, insulin secretion, the interaction of insulin with its target tissues, the mechanism of insulin action at the cellular level, and the defects which underlie both Type I (insulin-dependent diabetes mellitus, IDDM) and Type II (noninsulin-dependent diabetes mellitus, NIDDM) forms of the disease. We have chosen to focus the present volume on work related to insulin action.

Managing Diabetes and Hyperglycemia in the Hospital Setting

Author : Boris Draznin
Publisher : American Diabetes Association
ISBN 13 : 1580406572
Total Pages : 338 pages
Book Rating : 4.5/5 (84 download)

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Book Synopsis Managing Diabetes and Hyperglycemia in the Hospital Setting by : Boris Draznin

Download or read book Managing Diabetes and Hyperglycemia in the Hospital Setting written by Boris Draznin and published by American Diabetes Association. This book was released on 2016-05-20 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the number of patients with diabetes increases annually, it is not surprising that the number of patients with diabetes who are admitted to the hospital also increases. Once in the hospital, patients with diabetes or hyperglycemia may be admitted to the Intensive Care Unit, require urgent or elective surgery, enteral or parenteral nutrition, intravenous insulin infusion, or therapies that significantly impact glycemic control (e.g., steroids). Because many clinical outcomes are influenced by the degree of glycemic control, knowledge of the best practices in inpatient diabetes management is extremely important. The field of inpatient management of diabetes and hyperglycemia has grown substantially in the last several years. This body of knowledge is summarized in this book, so it can reach the audience of hospitalists, endocrinologists, nurses and other team members who take care of hospitalized patients with diabetes and hyperglycemia.

Hypoglycemia in Diabetes

Author : Philip Cryer
Publisher : American Diabetes Association
ISBN 13 : 1580406491
Total Pages : 194 pages
Book Rating : 4.5/5 (84 download)

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Book Synopsis Hypoglycemia in Diabetes by : Philip Cryer

Download or read book Hypoglycemia in Diabetes written by Philip Cryer and published by American Diabetes Association. This book was released on 2016-07-12 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intended for diabetes researchers and medical professionals who work closely with patients with diabetes, this newly updated and expanded edition provides new perspectives and direct insight into the causes and consequences of this serious medical condition from one of the foremost experts in the field. Using the latest scientific and medical developments and trends, readers will learn how to identify, prevent, and treat this challenging phenomenon within the parameters of the diabetes care regimen.

Diabetes: from Research to Clinical Practice

Author : Md. Shahidul Islam
Publisher : Springer Nature
ISBN 13 : 3030510891
Total Pages : 577 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Diabetes: from Research to Clinical Practice by : Md. Shahidul Islam

Download or read book Diabetes: from Research to Clinical Practice written by Md. Shahidul Islam and published by Springer Nature. This book was released on 2020-11-06 with total page 577 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes mellitus is a major public health problem affecting over 415 million people in the world. Extensive research over the decades and the recent discovery of new medicines have revolutionized our understanding and treatment of both type 2 diabetes and type 1 diabetes mellitus. This book contains selected topics that describe recent advances in research, and state of the art treatment of the two types of diabetes mellitus and their complications. The topics encompass epidemiology and pathogenesis of diabetes, clinical features, diagnosis and treatment of diabetes and related complications. The chapters contain essential background materials, as well as recent advances in researches in different aspects of diabetes mellitus. The books is expected to be useful for researchers, research students, as well as for the clinicians engaged in diabetes care and diabetes research.

Mechanisms of Insulin Action

Author : Alan R. Saltiel
Publisher : Springer Science & Business Media
ISBN 13 : 0387722041
Total Pages : 223 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Mechanisms of Insulin Action by : Alan R. Saltiel

Download or read book Mechanisms of Insulin Action written by Alan R. Saltiel and published by Springer Science & Business Media. This book was released on 2007-10-05 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: More than 18 million people in the United States have diabetes mellitus, and about 90% of these have the type 2 form of the disease. This book attempts to dissect the complexity of the molecular mechanisms of insulin action with a special emphasis on those features of the system that are subject to alteration in type 2 diabetes and other insulin resistant states. It explores insulin action at the most basic levels, through complex systems.

The Discovery of Insulin

Author : Michael Bliss
Publisher : University of Toronto Press
ISBN 13 : 1487516746
Total Pages : 524 pages
Book Rating : 4.4/5 (875 download)

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Book Synopsis The Discovery of Insulin by : Michael Bliss

Download or read book The Discovery of Insulin written by Michael Bliss and published by University of Toronto Press. This book was released on 2017-06-22 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt: The discovery of insulin at the University of Toronto in 1921-22 was one of the most dramatic events in the history of the treatment of disease. Insulin was a wonder-drug with ability to bring patients back from the very brink of death, and it was no surprise that in 1923 the Nobel Prize for Medicine was awarded to its discoverers, the Canadian research team of Banting, Best, Collip, and Macleod. In this engaging and award-winning account, historian Michael Bliss recounts the fascinating story behind the discovery of insulin – a story as much filled with fiery confrontation and intense competition as medical dedication and scientific genius. Originally published in 1982 and updated in 1996, The Discovery of Insulin has won the City of Toronto Book Award, the Jason Hannah Medal of the Royal Society of Canada, and the William H. Welch Medal of the American Association for the History of Medicine.

Medical Management of Type 1 Diabetes

Author : Cecilia C. Low Wang
Publisher : American Diabetes Association
ISBN 13 : 1580406777
Total Pages : 253 pages
Book Rating : 4.5/5 (84 download)

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Book Synopsis Medical Management of Type 1 Diabetes by : Cecilia C. Low Wang

Download or read book Medical Management of Type 1 Diabetes written by Cecilia C. Low Wang and published by American Diabetes Association. This book was released on 2016-11-15 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: Type 1 diabetes, formerly known as juvenile diabetes, is a complex disorder that requires a great deal of patient-guided self-care. In recent years, advances in diabetes treatment have dramatically shifted potential outcomes in the favor of the patient with diabetes. The challenge for health care professionals is to realize this potential through an individualized, flexible, and responsive treatment plan for patients with type 1 diabetes. Now in its seventh edition, Medical Management of Type 1 Diabetes offers health care providers the newest information and guidelines for the treatment of type 1 diabetes. Built on the foundation of multiple daily insulin injections and insulin pump therapy, this book guides health care providers in helping their patients continually strive for optimal blood glucose control. This new edition focuses on the latest molecular advances, new treatment methods, recent clinical trials, and the American Diabetes Association's Standards of Care. Key topics also include new insulins and administration protocols, advanced carbohydrate counting, and emphasis on continuing patient education. Individual sections address all of the topics in managing type 1 diabetes, including diagnosis and classification/pathogenesis, diabetes standards and education, tools of therapy, special situations, psychosocial factors affecting adherence, quality of life, and well-being and complications. Medical Management of Type 1 Diabetes is an essential addition to any clinician's library for the treatment and understanding of type 1 diabetes.

Insulin Therapy

Author : Mark W. J. Strachan
Publisher : Springer Science & Business Media
ISBN 13 : 144714760X
Total Pages : 86 pages
Book Rating : 4.4/5 (471 download)

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Book Synopsis Insulin Therapy by : Mark W. J. Strachan

Download or read book Insulin Therapy written by Mark W. J. Strachan and published by Springer Science & Business Media. This book was released on 2013-02-20 with total page 86 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this book is to provide clear and concise information about the safe prescribing of insulin both subcutaneously and intravenously. It provides information on the different types of insulin, the delivery devices, side effects of insulin and, most importantly, on rational dose adjustment.

Diabetes in Clinical Practice

Author : Evanthia Diakoumopoulou
Publisher : John Wiley & Sons
ISBN 13 : 0470059133
Total Pages : 482 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Diabetes in Clinical Practice by : Evanthia Diakoumopoulou

Download or read book Diabetes in Clinical Practice written by Evanthia Diakoumopoulou and published by John Wiley & Sons. This book was released on 2007-04-30 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dealing with all the aspects of diabetes in clinical practice, this book offers a comprehensive, easy-to-use guide to help healthcare professionals achieve their target of optimal management and treatment of their patients. Diabetes in Clinical Practice: Questions and Answers from Case Studies is presented in the form of questions concerning diabetes diagnosis, management and therapy based on real-life case studies. Each question is answered in a clear, easy to follow style. The authors begin with general questions regarding diabetes, its pathophysiology and diagnostic tests. They then cover all the major complications that can arise in a patient with poorly controlled diabetes. The authors also discuss special groups, such as adolescents and the elderly. The book features useful information for patients and their healthcare professionals on daily activities such as exercise, nutrition, driving, travelling and sick day rules. Diabetes in Clinical Practice: Questions and Answers from Case Studies is an indispensable resource for all members of the diabetes team, in primary and secondary care: physicians, diabetes specialist nurses, diabetes educators, dieticians, podiatrists, endocrinologists and postgraduate medical students.

Medical Management of Diabetes Mellitus

Author : William T. Cefalu
Publisher : CRC Press
ISBN 13 : 9781420001631
Total Pages : 776 pages
Book Rating : 4.0/5 (16 download)

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Book Synopsis Medical Management of Diabetes Mellitus by : William T. Cefalu

Download or read book Medical Management of Diabetes Mellitus written by William T. Cefalu and published by CRC Press. This book was released on 2000-02-17 with total page 776 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a how-to manual for practicing physicians and health care providers, nurse educators, nutritionists, and physicians in training in the management of persons with diabetes mellitus. Experts with strong clinical and teaching backgrounds provide up-to-date recom-mendations and rationale of the most effective diagnostic and therapeutic approaches to diabetes mellitus and its multiorgan micro- and macrovascular complications for patients of all ages.Gives five practical guidelines for nutrition therapy that supplies realistic recommendations!With contributions from nearly 60 clinicians who reveal a constellation of disorders with different signs, symptoms, clinical characteristics, and therapies, Medical Management of Diabetes Mellitusreviews the autoimmune process and genetics of type 1 and type 2 diabetes offers an overview of the medications that impair glucose metabolism causing hypo- or hyperglycemia covers pathogenesis, clinical presentation, and diagnosis with specialized laboratory tests surveys therapeutic modalities, their mechanisms of action, and rationale for use focuses on outcomes and how they are tracked stresses early detection and therapy of end-organ complications discusses the effect of intensive diabetes management on reducing retinopathy, nephropathy, and neuropathy considers incorporating psychiatric techniques into the treatment of diabetes compares and contrasts diabetes in children, adults, and the elderly and more!Containing over 850 references, tables, drawings, and photographs, Medical Management of Diabetes Mellitus is a cross-disciplinary reference perfect for family practice physicians, internists, pediatricians, endocrinologists, pharmacologists, nutritionists, physiologists, dietitians, obesity specialists, psychiatrists, and medical school students in these disciplines.

Galenics of Insulin

Author : Jens Brange
Publisher : Springer Science & Business Media
ISBN 13 : 3662025264
Total Pages : 108 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis Galenics of Insulin by : Jens Brange

Download or read book Galenics of Insulin written by Jens Brange and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: Galenical pharmacy or galenics is the science dealing with the pro duction of drug substances from raw materials, the purity of such substances, their formulation into pharmaceutical preparations with the desired effects and safety in use, and the quality control, stability and storage of the preparations. The field has taken its name from the Greek physician Galen (131-201 A.D.), who had a profound influence on medicine for many centuries because he collected and systematized the medicinal knowledge of his time. The discovery of insulin is attributed to Banting and Best who, in 1921, prepared an extract of the pancreas of the fetal calf and showed that the extract was capable of reducing the blood sugar level of a diabetic dog. This outstanding discovery gave rise to the rapid develop ment of the manufacture of insulin of bovine and porcine origin. By 1925, two Danish manufacturers of insulin preparations were established; both have since been in the forefront ofthe development of insulin preparations, the latest achievement being the marketing of human insulin by Novo in 1982. The development of highly purified human insulin produced semisynthetically from porcine insulin or by DNA recombinant methods are significant contributions to safe and efficient insulin therapy. Insulin is a protein which is destroyed in the gastrointestinal tract.

Diabetes Mellitus in Children

Author : Mark A. Sperling
Publisher :
ISBN 13 : 9781416027539
Total Pages : 0 pages
Book Rating : 4.0/5 (275 download)

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Book Synopsis Diabetes Mellitus in Children by : Mark A. Sperling

Download or read book Diabetes Mellitus in Children written by Mark A. Sperling and published by . This book was released on 2005 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Diabetes in Practice

Author : Boris Draznin
Publisher : American Diabetes Association
ISBN 13 : 1580407803
Total Pages : 329 pages
Book Rating : 4.5/5 (84 download)

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Book Synopsis Diabetes in Practice by : Boris Draznin

Download or read book Diabetes in Practice written by Boris Draznin and published by American Diabetes Association. This book was released on 2022-10-26 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes clinical practice is a life-long learning experience, and the insights presented in Diabetes in Practice will facilitate a deeper knowledge of the complex nature of diabetes and its comorbidities for physicians, nurse practitioners, registered dietitians, diabetes educators, and students. Diabetes in Practice offers a deep look into years of the professional practice of clinical diabetes. The 49 case studies Boris Draznin, MD, PhD, has assembled cover a wide array of diabetes cases involving atypical presentations to those addressing ketoacidosis and hypoglycemia, continuous glucose monitoring and insulin pumps, and diabetes co-occurring with cancer and autoimmune conditions. Each case study includes expert review from long-term diabetes practitioners to help you in your daily interactions with patients and enhance your understanding of diabetes diagnosis and treatment challenges.

Insulin Therapy Made Easy

Author : Sanjay Kalra
Publisher : Jaypee Brothers Medical Publishers
ISBN 13 : 938958793X
Total Pages : 125 pages
Book Rating : 4.3/5 (895 download)

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Book Synopsis Insulin Therapy Made Easy by : Sanjay Kalra

Download or read book Insulin Therapy Made Easy written by Sanjay Kalra and published by Jaypee Brothers Medical Publishers. This book was released on 2020-05-31 with total page 125 pages. Available in PDF, EPUB and Kindle. Book excerpt: Insulin is a protein hormone that is used as a medication to treat high blood glucose. This includes in diabetes mellitus type 1, diabetes mellitus type 2, gestational diabetes, and complications of diabetes. This book is a concise guide to the basics and clinical pharmacology of insulin, and the practical aspects of its use. Beginning with an overview of the development of insulins and normal physiology and metabolism, the next section examines different types of insulin (rapid-acting, short-acting, intermediate-acting, long-acting, and mixed). The following sections cover insulin therapy in type 1 diabetes, type 2 diabetes and in specific population groups. The book concludes with discussion on practical aspects of insulin therapy. Authored primarily for postgraduate medical students, the practical text is further enhanced by clinical images and diagrams to assist learning. Key points Concise guide to the prescription and use of insulin therapy for postgraduate students Explains different types of insulin and their specific uses Covers type 1 and type 2 diabetes mellitus, and specific population groups Clinical images and diagrams further enhance learning

Diabetes and Insulin

Author :
Publisher :
ISBN 13 :
Total Pages : 16 pages
Book Rating : 4.3/5 (121 download)

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Book Synopsis Diabetes and Insulin by :

Download or read book Diabetes and Insulin written by and published by . This book was released on 1988 with total page 16 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The American Diabetes Association/JDRF Type 1 Diabetes Sourcebook

Author : Anne L. Peters
Publisher : American Diabetes Association
ISBN 13 : 1580405061
Total Pages : 729 pages
Book Rating : 4.5/5 (84 download)

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Book Synopsis The American Diabetes Association/JDRF Type 1 Diabetes Sourcebook by : Anne L. Peters

Download or read book The American Diabetes Association/JDRF Type 1 Diabetes Sourcebook written by Anne L. Peters and published by American Diabetes Association. This book was released on 2013-03-29 with total page 729 pages. Available in PDF, EPUB and Kindle. Book excerpt: The American Diabetes Association/JDRF Type 1 Diabetes Sourcebook serves as both an evidence-based reference work and consensus report outlining the most critical components of care for individuals with type 1 diabetes throughout their lifespan. The volume serves not only as a comprehensive guide for clinicians, but also reviews the evidence supporting these components of care and provides a perspective on the critical areas of research that are needed to improve our understanding of type 1 diabetes diagnosis and treatment. The volume focuses specifically on the needs of patients with type 1 diabetes and provides clear and detailed guidance on the current standards for the optimal treatment of type 1 diabetes from early childhood to later life. To accomplish the book’s editorial goals, Editors-in-Chief, Drs. Anne Peters and Lori Laffel, assembled an editorial steering committee of prominent research physicians, clinicians, and educators to develop the topical coverage. In addition, a Managing Editor was brought on to help the authors write and focus their chapters.