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Author : Katy Rezvani
Publisher : Frontiers Media SA
ISBN 13 : 2832531997
Total Pages : 226 pages
Book Rating : 4.8/5 (325 download)
Download or read book Insights in cancer immunity and immunotherapy: 2022 written by Katy Rezvani and published by Frontiers Media SA. This book was released on 2023-08-17 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Manel Juan
Publisher : Frontiers Media SA
ISBN 13 : 2832537316
Total Pages : 229 pages
Book Rating : 4.8/5 (325 download)
Download or read book Methods in Cancer Immunity and Immunotherapy: 2022 written by Manel Juan and published by Frontiers Media SA. This book was released on 2023-10-27 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Research Topic is part of the “Methods in Immunology” series. Please submit your article to the Research Topic that best suits the focus of your research. Introduction and general guidelines: This series aims to highlight the latest experimental techniques and methods used to investigate fundamental questions in Immunology research, with a focus on Cancer Immunity and Immunotherapy.
Author : Robert C. Rees
Publisher : Oxford University Press, USA
ISBN 13 : 0199676860
Total Pages : 469 pages
Book Rating : 4.1/5 (996 download)
Download or read book Tumor Immunology and Immunotherapy written by Robert C. Rees and published by Oxford University Press, USA. This book was released on 2014 with total page 469 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tumor immunology and immunotherapy provides a comprehensive account of cancer immunity and immunotherapy. Examining recent results, current areas of interest and the specific issues that are affecting the research and development of vaccines, this book provides insight into how these problems may be overcome as viewed by leaders in the field.
Author : Lisa H. Butterfield
Publisher :
ISBN 13 : 9781620700976
Total Pages : 0 pages
Book Rating : 4.7/5 (9 download)
Download or read book Cancer Immunotherapy Principles and Practice written by Lisa H. Butterfield and published by . This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part 1: Intratumoral Signatures Associated With Immune Responsiveness
Author : Catherine Sautes-Fridman
Publisher : Frontiers Media SA
ISBN 13 : 283252544X
Total Pages : 148 pages
Book Rating : 4.8/5 (325 download)
Download or read book A year in review: Discussions in cancer immunity and immunotherapy written by Catherine Sautes-Fridman and published by Frontiers Media SA. This book was released on 2023-06-07 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 : 9789811532672
Total Pages : 657 pages
Book Rating : 4.5/5 (326 download)
Download or read book Regulation of Cancer Immune Checkpoints written by and published by . This book was released on 2020 with total page 657 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book systematically reviews the most important findings on cancer immune checkpoints, sharing essential insights into this rapidly evolving yet largely unexplored research topic. The past decade has seen major advances in cancer immune checkpoint therapy, which has demonstrated impressive clinical benefits. The family of checkpoints for mediating cancer immune evasion now includes CTLA-4, PD-1/PD-L1, CD27/CD70, FGL-1/LAG-3, Siglec-15, VISTA (PD-1L)/VSIG3, CD47/SIRPA, APOE/LILRB4, TIGIT, and many others. Despite these strides, most patients do not show lasting remission, and some cancers have been completely resistant to the therapy. The potentially lethal adverse effects of checkpoint blockade represent another major challenge, the mechanisms of which remain poorly understood. Compared to the cancer signaling pathways, such as p53 and Ras, mechanistic studies on immune checkpoint pathways are still in their infancy. To improve the responses to checkpoint blockade therapy and limit the adverse effects, it is essential to understand the molecular regulation of checkpoint molecules in both malignant and healthy cells/tissues. This book begins with an introduction to immune checkpoint therapy and its challenges, and subsequently describes the regulation of checkpoints at different levels. In closing, it discusses recent therapeutic developments based on mechanistic findings, and outlines goals for future translational studies. The book offers a valuable resource for researchers in the cancer immunotherapy field, helping to form a roadmap for checkpoint regulation and develop safer and more effective immunotherapies.
Author : Mary Poupot-Marsan
Publisher : Frontiers Media SA
ISBN 13 : 2832548040
Total Pages : 256 pages
Book Rating : 4.8/5 (325 download)
Download or read book New insights into innate immune cell-based immunotherapies in cancer written by Mary Poupot-Marsan and published by Frontiers Media SA. This book was released on 2024-04-17 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Charles Graeber
Publisher : Hachette+ORM
ISBN 13 : 145556849X
Total Pages : 314 pages
Book Rating : 4.4/5 (555 download)
Download or read book The Breakthrough written by Charles Graeber and published by Hachette+ORM. This book was released on 2015-12-01 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: Follow along as this New York Times bestselling author details the astonishing scientific discovery of the code to unleashing the human immune system to fight in this "captivating and heartbreaking" book (The Wall Street Journal). For decades, scientists have puzzled over one of medicine's most confounding mysteries: Why doesn't our immune system recognize and fight cancer the way it does other diseases, like the common cold? As it turns out, the answer to that question can be traced to a series of tricks that cancer has developed to turn off normal immune responses -- tricks that scientists have only recently discovered and learned to defeat. The result is what many are calling cancer's "penicillin moment," a revolutionary discovery in our understanding of cancer and how to beat it. In The Breakthrough, New York Times bestselling author of The Good Nurse Charles Graeber guides readers through the revolutionary scientific research bringing immunotherapy out of the realm of the miraculous and into the forefront of twenty-first-century medical science. As advances in the fields of cancer research and the human immune system continue to fuel a therapeutic arms race among biotech and pharmaceutical research centers around the world, the next step -- harnessing the wealth of new information to create modern and more effective patient therapies -- is unfolding at an unprecedented pace, rapidly redefining our relationship with this all-too-human disease. Groundbreaking, riveting, and expertly told, The Breakthrough is the story of the game-changing scientific discoveries that unleash our natural ability to recognize and defeat cancer, as told through the experiences of the patients, physicians, and cancer immunotherapy researchers who are on the front lines. This is the incredible true story of the race to find a cure, a dispatch from the life-changing world of modern oncological science, and a brave new chapter in medical history.
Author : Xiao Liang
Publisher : Frontiers Media SA
ISBN 13 : 2832522467
Total Pages : 191 pages
Book Rating : 4.8/5 (325 download)
Download or read book Community series in novel insights into immunotherapy targeting tumor microenvironment in ovarian cancer, volume I written by Xiao Liang and published by Frontiers Media SA. This book was released on with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : William J. Liu
Publisher : Frontiers Media SA
ISBN 13 : 2832520510
Total Pages : 204 pages
Book Rating : 4.8/5 (325 download)
Download or read book Crystal clear: Visualizing the immune recognition for the mechanism and intervention written by William J. Liu and published by Frontiers Media SA. This book was released on 2023-04-12 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Takaji Matsutani
Publisher : Frontiers Media SA
ISBN 13 : 283254794X
Total Pages : 343 pages
Book Rating : 4.8/5 (325 download)
Download or read book Novel biomarkers in tumor immunity and immunotherapy written by Takaji Matsutani and published by Frontiers Media SA. This book was released on 2024-07-26 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immune checkpoint inhibitors (ICIs) such as anti-PD-1 and anti-PD-L1 antibodies are highly effective against many types of cancer, yet durable responses are limited to a subset of patients highlighting the need for the development of effective biomarkers to predict prognosis and efficacy. Currently, PD-L1 expression in tumors, microsatellite instability (MSI) or mismatch repair deficiency (dMMR), and tumor mutation burden (TMB) are known as biomarkers for cancer immunotherapy but are not sufficient. Combination therapy with immune checkpoint inhibitors and chemotherapy or radiation therapy, as well as diverse therapies targeting intra-tumoral regulatory T cells have been described, but there are currently no unifying biomarkers that are applicable to clinically, a simple, fast, non-invasive method that can yield biomarkers of disease with a minimal adverse effect on patients is desirable. Recent findings suggest that the balancing of effector T cells and regulatory cells in the tumor microenvironment is associated with cancer progression and prognosis. Cells and molecules involved in the control of cancer are complex, and a better understanding of the tumor immune environment will lead to the development of truly effective biomarkers. This topic will focus on novel biomarkers that predict efficacy, prognosis, or the development of adverse events in various cancer immunotherapies, and extensive basic research leading to the development of biomarkers. Manuscripts consisting solely of bioinformatics or computational analysis of public genomic or transcriptomic databases which are not accompanied by robust and relevant validation (clinical cohort or biological validation in vitro or in vivo) are out of scope for this topic. We expect a wide range of research, not only in serology, genetics, and immunocytochemistry but also in bacterial flora. Research on the development of novel assays and bioinformatics methods is also welcome: • Non-invasive biomarkers for cancer immunotherapy. • Bulk RNA-seq, scRNA-seq, or Rep-seq methods. • Correlation of tumor immune cells with gut microbiota in tumor immunotherapy. • Impact of Teff and Treg balance in the tumor microenvironment on tumor prognosis. • Inflammatory and immune signatures associated with drug response versus resistance in cancer.
Author : Glenn Dranoff
Publisher : Springer Science & Business Media
ISBN 13 : 3642141366
Total Pages : 313 pages
Book Rating : 4.6/5 (421 download)
Download or read book Cancer Immunology and Immunotherapy written by Glenn Dranoff and published by Springer Science & Business Media. This book was released on 2011-04-11 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: The interplay between tumors and their immunologic microenvironment is complex, difficult to decipher, but its understanding is of seminal importance for the development of novel prognostic markers and therapeutic strategies. The present review discusses tumor-immune interactions in several human cancers that illustrate various aspects of this complexity and proposes an integrated scheme of the impact of local immune reactions on clinical outcome. Current active immunotherapy trials have shown durable tumor regressions in a fraction of patients. However, clinical efficacy of current vaccines is limited, possibly because tumors skew the immune system by means of myeloid-derived suppressor cells, inflammatory type 2 T cells and regulatory T cells (Tregs), all of which prevent the generation of effector cells. To improve the clinical efficacy of cancer vaccines in patients with metastatic disease, we need to design novel and improved strategies that can boost adaptive immunity to cancer, help overcome Tregs and allow the breakdown of the immunosuppressive tumor microenvironment.
Author : Denise L. Doolan
Publisher : Frontiers Media SA
ISBN 13 : 283252446X
Total Pages : 160 pages
Book Rating : 4.8/5 (325 download)
Download or read book Insights in vaccines and molecular therapeutics: 2021 written by Denise L. Doolan and published by Frontiers Media SA. This book was released on 2023-05-31 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Adriana Albini
Publisher : Frontiers Media SA
ISBN 13 : 2832553869
Total Pages : 136 pages
Book Rating : 4.8/5 (325 download)
Download or read book Women in Cancer Immunity and Immunotherapy written by Adriana Albini and published by Frontiers Media SA. This book was released on 2024-08-30 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt: At present, less than 30% of researchers worldwide are women. Long-standing biases and gender stereotypes are discouraging girls and women away from science-related fields, and STEM research in particular. Science and gender equality are, however, essential to ensure sustainable development as highlighted by UNESCO. In order to change traditional mindsets, gender equality must be promoted, stereotypes defeated, and girls and women should be encouraged to pursue STEM careers. Therefore, Frontiers in Immunology is proud to offer this platform to promote the work of women scientists, across all fields of Cancer Immunity and Immunotherapy.
Author : Qian Xiao
Publisher : Frontiers Media SA
ISBN 13 : 2832513344
Total Pages : 303 pages
Book Rating : 4.8/5 (325 download)
Download or read book Immune Modulation in Tumor Microenvironment: New Perspectives for Cancer Immunotherapy written by Qian Xiao and published by Frontiers Media SA. This book was released on 2023-02-01 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Xuelei Ma
Publisher : Frontiers Media SA
ISBN 13 : 283253015X
Total Pages : 264 pages
Book Rating : 4.8/5 (325 download)
Download or read book Community series in immunotherapy with checkpoint inhibitors for non-small cell lung cancer, colon cancer and esophageal cancer, volume II written by Xuelei Ma and published by Frontiers Media SA. This book was released on 2023-07-27 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Peter Bailey
Publisher : Frontiers Media SA
ISBN 13 : 2889760049
Total Pages : 256 pages
Book Rating : 4.8/5 (897 download)
Download or read book Translational Insights Into Pancreatic Ductal Adenocarcinoma written by Peter Bailey and published by Frontiers Media SA. This book was released on 2022-04-26 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt:
