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Author : Roger Epton
Publisher :
ISBN 13 : 9780951573532
Total Pages : 414 pages
Book Rating : 4.5/5 (735 download)
Download or read book Innovation and Perspectives in Solid Phase Synthesis & Combinatorial Libraries 2000 written by Roger Epton and published by . This book was released on 2001 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Roger Epton
Publisher :
ISBN 13 :
Total Pages : 432 pages
Book Rating : 4.:/5 (18 download)
Download or read book Innovation and Perspectives in Solid Phase Synthesis & Combinatorial Libraries written by Roger Epton and published by . This book was released on 1999 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Roger Epton
Publisher :
ISBN 13 :
Total Pages : 376 pages
Book Rating : 4.F/5 ( download)
Download or read book Innovation and Perspectives in Solid Phase Synthesis & Combinatorial Libraries written by Roger Epton and published by . This book was released on 2004 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 :
Total Pages : 330 pages
Book Rating : 4.F/5 ( download)
Download or read book Innovation and Perspectives in Solid Phase Synthesis & Combinatorial Libraries, 2002 written by and published by . This book was released on 2003 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Innovation and Perspectives in Solid Phase Synthesis written by and published by . This book was released on 1990 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Bing Yan
Publisher : CRC Press
ISBN 13 : 1482271052
Total Pages : 408 pages
Book Rating : 4.4/5 (822 download)
Download or read book Optimization of Solid-Phase Combinatorial Synthesis written by Bing Yan and published by CRC Press. This book was released on 2001-12-04 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Addresses the key topic in combinatorial synthesis--how to optimize the quality of a combinatorial library--by determining the usefulness of synthesized compunds, the reliability of biological assay results, and analyzing acadmic and industrial applications, real-world examples, and case studies of successful and unsuccessful technologies."
Author : Pierfausto Seneci
Publisher : John Wiley & Sons
ISBN 13 : 0471460737
Total Pages : 653 pages
Book Rating : 4.4/5 (714 download)
Download or read book Solid-Phase Synthesis and Combinatorial Technologies written by Pierfausto Seneci and published by John Wiley & Sons. This book was released on 2003-05-28 with total page 653 pages. Available in PDF, EPUB and Kindle. Book excerpt: A unique, integrated look at solid-phase synthesis and advances in combinatorial chemistry and technologies The last decade has seen a rapid expansion in combinatorial technologies, a field where chemistry disciplines intersect with automation, statistics, and information science, as well as certain biological disciplines. Reflecting these multidisciplinary trends, this new work provides a comprehensive overview of the most important aspects of solid-phase synthesis (SPS), combinatorial chemistry, and related combinatorial technologies. It clearly demonstrates how SPS and combinatorial chemistry have extended their application from the pharmaceutical arena to new areas, including biotechnology, material sciences, catalysis, and agrochemical industries, and explores in detail strategies for planning, designing, preparing, and testing of combinatorial libraries in various disciplines. Designed to meet the needs of both experienced combinatorial chemists and newcomers to the field, Solid-Phase Synthesis and Combinatorial Technologies: * Surveys the most recent developments in SPS and combinatorial chemistry * Explains the entire process, from determining the need for a library to the details necessary for synthesis of the library * Discusses choice of format, size, and the rationale behind the design of each synthetic step * Surveys the analytical techniques and the purification methods used to characterize and purify combinatorial libraries * Employs a large number of examples to illustrate important concepts * Includes problems geared toward applying acquired knowledge and designing the steps to SPS/library synthesis * Describes the quality control and activity screening of combinatorial libraries for various applications * Features a detailed bibliography of more than 1,700 relevant sources
Author : Roger Epton
Publisher :
ISBN 13 :
Total Pages : 472 pages
Book Rating : 4.F/5 ( download)
Download or read book Innovation and Perspectives in Solid Phase Synthesis & Combinatorial Libraries, 1998 written by Roger Epton and published by . This book was released on 1999 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Roger Epton
Publisher :
ISBN 13 :
Total Pages : 540 pages
Book Rating : 4.:/5 (112 download)
Download or read book Innovation and Perspectives in Solid Phase Synthesis written by Roger Epton and published by . This book was released on 1992 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : D. Obrecht
Publisher : Elsevier
ISBN 13 : 9780080432571
Total Pages : 366 pages
Book Rating : 4.4/5 (325 download)
Download or read book Solid-supported Combinatorial and Parallel Synthesis of Small-molecular-weight Compound Libraries written by D. Obrecht and published by Elsevier. This book was released on 1998-10-16 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gives an overview of the current state of the art of combinatorial organic synthesis. While the main focus is on multicomponent and multigeneration strategies using polymeric supports, there is also a Chapter on solution strategies using polymer-grafted reagents which allow minimisation of work-up procedures. Some of the most important strategies and tools are presented and summarised, with an explanation of the pivotal role of organic synthesis in the creation of diversity.
Author : Jean-Philippe Goddard
Publisher : John Wiley & Sons
ISBN 13 : 111969504X
Total Pages : 162 pages
Book Rating : 4.1/5 (196 download)
Download or read book Biphasic Chemistry and The Solvent Case written by Jean-Philippe Goddard and published by John Wiley & Sons. This book was released on 2020-01-09 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biphasic Chemistry and The Solvent Case examines recent improvements in reaction conditions, in order to affirm the role of chemistry in the sustainable field. This book shows that those who work within the chemistry industry support limits for the use of toxic or flammable solvents, since it reduces the purifications to simple filtrations. Thanks to commercial scavengers, solid phase syntheses are now available to all. Fluorine biphasic catalysis enables extremely efficient catalyst recycling and has a high applicability potential at the industrial level. This book also reviews the many studies that have shown that water is a solvent of choice for most synthetic reactions. Particular traits can be obtained and the effects on thermodynamics make it possible to operate at lower temperatures, thereby achieving energy savings. Finally the great diversity of application of the reactions without solvents is illustrated.
Author : Günther Jung
Publisher : John Wiley & Sons
ISBN 13 : 352761351X
Total Pages : 634 pages
Book Rating : 4.5/5 (276 download)
Download or read book Combinatorial Chemistry written by Günther Jung and published by John Wiley & Sons. This book was released on 2008-07-11 with total page 634 pages. Available in PDF, EPUB and Kindle. Book excerpt: The story of success goes on and on - with a new book on combinatorial chemistry, edited by Gunther Jung! Combinatorial chemistry is a proven time- and resource-saving synthetic method of outstanding importance for industrial processes. Compound libraries help to save time and money, especially in the search for new drugs, and therefore play a pivotal role in solving the problem of the worldwide increasing demand for new and more active drugs. Not only substances, which are of interest for pharmaceutical chemistry, but also materials, catalysts, and biomolecules such as DNA or oligosaccharides are readily available with high structural diversities. The broad scope of combinatorial sciences is reflected by this book, edited by Gunther Jung: The synthetic methods discussed range from solid-phase to solution-phase synthesis, from preparations of small molecules such as amines or alcohols to those of complex biomolecules. Feasible methods, efficient techniques, new trends in automation, and state-of-the-art fast instrumental analytical and screening methods are presented with many practical tips and tricks for everybody working in combinatorial chemistry. This is the book written by specialists for specialists and for everyone aspiring to become an insider! It is an indispensible source of information for researchers working in organic synthesis, catalysis, biochemistry, and biotechnology, pharmaceutical and clinical chemistry, material sciences, and analytical chemistry.
Author : Patrick H. Toy
Publisher : John Wiley & Sons
ISBN 13 : 1118141636
Total Pages : 560 pages
Book Rating : 4.1/5 (181 download)
Download or read book Solid-Phase Organic Synthesis written by Patrick H. Toy and published by John Wiley & Sons. This book was released on 2012-01-10 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents both the fundamental concepts and the most recent applications in solid-phase organic synthesis With its emphasis on basic concepts, Solid-Phase Organic Synthesis guides readers through all the steps needed to design and perform successful solid-phase organic syntheses. The authors focus on the fundamentals of heterogeneous supports in the synthesis of organic molecules, explaining the use of a solid material to facilitate organic synthesis. This comprehensive text not only presents the fundamentals, but also reviews the most recent research findings and applications, offering readers everything needed to conduct their own state-of-the-art science experiments. Featuring chapters written by leading researchers in the field, Solid-Phase Organic Synthesis is divided into two parts: Part One, Concepts and Strategies, discusses the linker groups used to attach the synthesis substrate to the solid support, colorimetric tests to identify the presence of functional groups, combinatorial synthesis, and diversity-oriented synthesis. Readers will discover how solid-phase synthesis is currently used to facilitate the discovery of new molecular functionality. The final chapter discusses how using a support can change or increase reaction selectivity. Part Two, Applications, presents examples of the solid-phase synthesis of various classes of organic molecules. Chapters explore general asymmetric synthesis on a support, strategies for heterocyclic synthesis, and synthesis of radioactive organic molecules, dyes, dendrimers, and oligosaccharides. Each chapter ends with a set of conclusions that underscore the key concepts and methods. References in each chapter enable readers to investigate any topic in greater depth. With its presentation of basic concepts as well as recent findings and applications, Solid-Phase Organic Synthesis is the ideal starting point for students and researchers in organic, medicinal, and combinatorial chemistry who want to take full advantage of current solid-phase synthesis techniques.
Author : Fernando Albericio
Publisher : CRC Press
ISBN 13 : 1482270307
Total Pages : 849 pages
Book Rating : 4.4/5 (822 download)
Download or read book Solid-Phase Synthesis written by Fernando Albericio and published by CRC Press. This book was released on 2000-04-28 with total page 849 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides the information needed to synthesize peptides by solid-phase synthesis (SPS) - employing polymeric support (resins), anchoring linkages (handles), coupling reagents (activators), and protection schemes. It presents strategies for creating a wide variety of compounds for drug discovery and analyzes peptides, DNA, carbohydrates,
Author : Geoffrey W. Tregear
Publisher : Springer Science & Business Media
ISBN 13 : 9401728771
Total Pages : 440 pages
Book Rating : 4.4/5 (17 download)
Download or read book Relaxin 2000 written by Geoffrey W. Tregear and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first international forum on relaxin was a workshop held in Hawaii in 1980. This was followed by the Kroc Foundation conference in Santa Ynes, California in 1981 and then the First International Congress on the Hormone Relaxin in Florence in 1982. After a hiatus of several years, the Second International Congress on the Hormone Relaxin was held in Adelaide in 1994. Since that time, the enormous advances in molecular biology and protein chemistry have led to a stellar growth in relaxin research. Novel sites of action of the hormone have been elucidated, numerous new mammalian primary structures determined, more detailed mechanisms of action postulated, the control of relaxin secretion better understood, non-pregnant roles of the hormone identified, and, importantly, relaxin-related peptides (particularly INSL 3 and 5) identified and possible synergistic actions with relaxin proposed. A raft of novel clinical applications of relaxin has also been explored. Together, these exciting developments made the time ripe for a third international conference. We were therefore delighted to welcome many colleagues, old and new, at Relaxin 2000, the first international forum on relaxin and related peptides in the new Millennium. This conference, which we hope will now be held every four to five years, was held at the Cable Beach Inter-Continental Resort at the delightful old pearling town of Broome in the far north-west of Australia from 22-27 October, 2000.
Author : Armen M. Boldi
Publisher : CRC Press
ISBN 13 : 1000612015
Total Pages : 354 pages
Book Rating : 4.0/5 (6 download)
Download or read book Combinatorial Synthesis of Natural Product-Based Libraries written by Armen M. Boldi and published by CRC Press. This book was released on 2006-05-16 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traditionally, the search for new compounds from natural products has been a time- and resource-intensive process. The recent application of combinatorial methods and high-throughput synthesis has allowed scientists to generate a range of new molecular structures from natural products and observe how they interact with biological targets. Combinato
Author : John Howl
Publisher : Springer Science & Business Media
ISBN 13 : 1592598773
Total Pages : 263 pages
Book Rating : 4.5/5 (925 download)
Download or read book Peptide Synthesis and Applications written by John Howl and published by Springer Science & Business Media. This book was released on 2008-02-02 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hands-on experts describe in step-by-step detail the key methodologies of contemporary peptide synthesis and illustrate their numerous applications. The techniques presented include protocols for chemical ligation, the synthesis of cyclic and phosphotyrosine-containing peptides, lipoamino acid- and sugar-conjugated peptides, and peptide purification and analyses. Additional chapters detail methodologies and instrumentation for high-throughput peptide synthesis, many different applications of peptides as novel research tools and biological probes, and the design and application of fluorescent substrate-based peptides that can be used to determine the selectivity and activity of peptidases. A practical guide to the identification of proteins using mass spectrometric analyses of peptide mixtures is also included.
