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Innate Immunity
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Book Synopsis Janeway's Immunobiology by : Kenneth Murphy
Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Innate Immunity: Resistance and Disease-Promoting Principles by : G. Hartmann
Download or read book Innate Immunity: Resistance and Disease-Promoting Principles written by G. Hartmann and published by Karger Medical and Scientific Publishers. This book was released on 2013-06-05 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our understanding of the complex innate immune response is increasing rapidly. Its role in the protection against viral or bacterial pathogens is essential for the survival of an organism. However, it is equally important to avoid unregulated inflammation because innate immune responses can cause or promote chronic autoinflammatory diseases such as gout, atherosclerosis, type 2 diabetes or certain aspects of the metabolic syndrome. In this book leading international experts in the field of innate immunity share their findings, define the ‚state of the art‘ in this field and evaluate how insight into the molecular basis of these diseases could help in the design of new therapies. A tremendous amount of work on the innate immune response has been done over the last fifteen years, culminating in the 2011 Nobel Prize in Physiology/Medicine awarded for the discoveries of Toll genes in immunity in flies, membrane-bound Toll-like receptors in mammals, and dendritic cells as initiators of adaptive immunity.
Book Synopsis Innate Immunity and Inflammation by : Ruslan Medzhitov
Download or read book Innate Immunity and Inflammation written by Ruslan Medzhitov and published by Cold Spring Harbor Perspective. This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "A subject collection from Cold Spring Harbor perspectives in biology."
Book Synopsis The Innate Immune System by : Tomi Monie
Download or read book The Innate Immune System written by Tomi Monie and published by Academic Press. This book was released on 2017-02-20 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Innate Immune System: A Compositional and Functional Perspective focuses on the components and functionality of the innate immune system, detailing how they work in their own right, and then progressing to cover their relevance to disease and how they interface with the adaptive response. Despite the growing appreciation of the importance of the innate immune system, many classical immunology books still focus predominantly on the adaptive immune response. Not only is this unbalanced, but it fails to reflect the growing synergy between the activation and function of the innate response and the final nature of adaptive response. This book fills the gap in knowledge that is needed to fully understand and appreciate the topic.
Download or read book Antibody Fc written by Margaret Ackerman and published by Academic Press. This book was released on 2013-08-06 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antibody Fc is the first single text to synthesize the literature on the mechanisms underlying the dramatic variability of antibodies to influence the immune response. The book demonstrates the importance of the Fc domain, including protective mechanisms, effector cell types, genetic data, and variability in Fc domain function. This volume is a critical single-source reference for researchers in vaccine discovery, immunologists, microbiologists, oncologists and protein engineers as well as graduate students in immunology and vaccinology. Antibodies represent the correlate of protection for numerous vaccines and are the most rapidly growing class of drugs, with applications ranging from cancer and infectious disease to autoimmunity. Researchers have long understood the variable domain of antibodies, which are responsible for antigen recognition, and can provide protection by blocking the function of their target antigen. However, recent developments in our understanding of the protection mediated by antibodies have highlighted the critical nature of the antibody constant, or Fc domain, in the biological activity of antibodies. The Fc domain allows antibodies to link the adaptive and innate immune systems, providing specificity to a wide range of innate effector cells. In addition, they provide a feedback loop to regulate the character of the immune response via interactions with B cells and antigen-presenting cells. - Clarifies the different mechanisms of IgG activity at the level of the different model systems used, including human genetic, mouse, and in vitro - Covers the role of antibodies in cancer, infectious disease, and autoimmunity and in the setting of monoclonal antibody therapy as well as naturally raised antibodies - Color illustrations enhance explanations of the immune system
Book Synopsis Switching on Plant Innate Immunity Signaling Systems by : P. Vidhyasekaran
Download or read book Switching on Plant Innate Immunity Signaling Systems written by P. Vidhyasekaran and published by Springer. This book was released on 2016-01-23 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the ways and means to switch on plant immune signaling systems using PAMP-PIMP-PRR signaling complex for crop disease management. It also describes bioengineering approaches to develop transgenic plants expressing enhanced disease resistance using genes encoding PAMPs, PRRs and transcription factors and genes involved in generation of PIMPs/HAMPs. It also discusses recent commercial development of PAMP products to switch on plant innate immunity for crop disease management. These unique approaches have been described with more than 100 figures and illustrations and these would make this book attractive for researchers and students to buy this book.
Book Synopsis Mouse Models of Innate Immunity by : Irving C. Allen
Download or read book Mouse Models of Innate Immunity written by Irving C. Allen and published by Humana. This book was released on 2016-08-27 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The innate immune system represents a critical arm of the immune response by providing immediate and robust host defense; however, human studies of its function are often limited by ethical, logistical, and technical obstacles. In Mouse Models of Innate Immunity: Methods and Protocols, experts in the field explore the design and execution of experiments used to thoroughly evaluate critical elements associated with the host innate immune response. The volume opens with methods that are essential for collecting and assessing various primary cells that are highly relevant to innate immunity, and it continues with in vivo protocols commonly used to evaluate the innate immune response in the mouse, including mouse models of respiratory infection, gastrointestinal inflammation, fungal and parasitic diseases, sepsis, and HIV-1 infection. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and easy to use, Mouse Models of Innate Immunity: Methods and Protocols will serve the research community by providing expert advice and protocols that allow both experienced and novice investigators to successfully plan, implement, and assess disease processes associated with the innate immune response.
Book Synopsis The Innate Immune Response to Noninfectious Stressors by : Massimo Amadori
Download or read book The Innate Immune Response to Noninfectious Stressors written by Massimo Amadori and published by Academic Press. This book was released on 2016-02-23 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Innate Immune Response to Non-infectious Stressors: Human and Animal Models highlights fundamental mechanisms of stress response and important findings on how the immune system is affected, and in turn affects such a response. In addition, this book covers the crucial link between stress response and energy metabolism, prompts a re-appraisal of some crucial issues, and helps to define research priorities in this fascinating, somehow elusive field of investigation. - Provides insights into the fundamental homeostatic processes vis-à-vis stressors to help in investigation - Illustrates the depicted tenets and how to offset them against established models of response to physical and psychotic stressors in both animals and humans - Covers the crucial issue of the immune response to endocrine disruptors - Includes immunological parameters as reporter system of environmental adaptation - Provides many illustrative examples to foster reader understanding
Book Synopsis Fundamentals of Inflammation by : Charles N. Serhan
Download or read book Fundamentals of Inflammation written by Charles N. Serhan and published by Cambridge University Press. This book was released on 2010-04-26 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: The acute inflammatory response is the body's first system of alarm signals that are directed toward containment and elimination of microbial invaders. Uncontrolled inflammation has emerged as a pathophysiologic basis for many widely occurring diseases in the general population that were not initially known to be linked to the inflammatory response, including cardiovascular disease, asthma, arthritis, and cancer. To better manage treatment, diagnosis, and prevention of these wide-ranging diseases, multidisciplinary research efforts are underway in both academic and industry settings. This book provides an introduction to the cell types, chemical mediators, and general mechanisms of the host's first response to invasion. World-class experts from institutions around the world have written chapters for this introductory text. The text is presented as an introductory springboard for graduate students, medical scientists, and researchers from other disciplines wishing to gain an appreciation and working knowledge of current cellular and molecular mechanisms fundamental to inflammation.
Book Synopsis Experimental Approaches For The Investigation Of Innate Immunity: The Human Innate Immunity Handbook by : Richard Bucala
Download or read book Experimental Approaches For The Investigation Of Innate Immunity: The Human Innate Immunity Handbook written by Richard Bucala and published by World Scientific. This book was released on 2016-01-15 with total page 181 pages. Available in PDF, EPUB and Kindle. Book excerpt: The recent explosion of information in innate immune pathways for recognition, effect or responses, and genetic regulation has given impetus to investigations into analogous pathways in the human immune response, which in turn has produced attendant insights into both normal physiology and immunopathology. This volume presents a compendium of methods and protocols for the investigation of human innate immunity with application to the study of normal immune function, immunosenescence, autoimmunity and infectious diseases. Among the topics covered are quantitative flow cytometry for Toll-like receptor expression and function; multidimensional single cell mass cytometry (CyTOF) in complex immune interactions and tumor immunity; imaging techniques such as Imagestream high resolution microscopy coupled to flow cytometry, immune cell infiltration of organotypic, biomimetic organs; high-throughput single cell secretion profiling; multiplexed transcriptomic profiling; microsatellite and microRNA methodologies, RNA interference; and the latest bioinformatics and biostatistical methodologies, including in-depth statistical modeling, genetic mapping, and systems approaches.
Book Synopsis Toll-Like Receptors (TLRs) and Innate Immunity by : Stefan Bauer
Download or read book Toll-Like Receptors (TLRs) and Innate Immunity written by Stefan Bauer and published by Springer Science & Business Media. This book was released on 2007-12-11 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: Overall recent research on TLRs has led to tremendous increase in our understanding of early steps in pathogen recognition and will presumably lead to potent TLR targeting therapeutics in the future. This book reviews and highlights our recent understanding on the function and ligands of TLRs as well as their role in autoimmunity, dendritic cell activation and target structures for therapeutic intervention.
Book Synopsis Invertebrate Immunity by : Kenneth Söderhäll
Download or read book Invertebrate Immunity written by Kenneth Söderhäll and published by Springer Science & Business Media. This book was released on 2011-06-28 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: It can be seen that the insects are the still attracting most research and researchers. However, an increasing interest is emerging to study new invertebrate groups, especially those where the genome is known. Even though Drosophila has been and still is an excellent model for immune studies, it is now clear that there are great differences between immune responses in Drosophila and that of several other invertebrates, which indeed calls for more research on other invertebrates
Book Synopsis Concepts of Biology by : Samantha Fowler
Download or read book Concepts of Biology written by Samantha Fowler and published by . This book was released on 2023-05-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Black & white print. Concepts of Biology is designed for the typical introductory biology course for nonmajors, covering standard scope and sequence requirements. The text includes interesting applications and conveys the major themes of biology, with content that is meaningful and easy to understand. The book is designed to demonstrate biology concepts and to promote scientific literacy.
Book Synopsis Plant Innate Immunity Signals and Signaling Systems by : P. Vidhyasekaran
Download or read book Plant Innate Immunity Signals and Signaling Systems written by P. Vidhyasekaran and published by Springer Nature. This book was released on 2020-04-15 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: The volume III of the book presents the ways and means to manipulate the signals and signaling system to enhance the expression of plant innate immunity for crop disease management. It also describes bioengineering approaches to develop transgenic plants expressing enhanced disease resistance using plant immunity signaling genes. It also discusses recent commercial development of biotechnological products to manipulate plant innate immunity for crop disease management. Engineering durable nonspecific resistance to phytopathogens is one of the ultimate goals of plant breeding. However, most of the attempts to reach this goal fail as a result of rapid changes in pathogen populations and the sheer diversity of pathogen infection mechanisms. Recently several bioengineering and molecular manipulation technologies have been developed to activate the ‘sleeping’ plant innate immune system, which has potential to detect and suppress the development of a wide range of plant pathogens in economically important crop plants. Enhancing disease resistance through altered regulation of plant immunity signaling systems would be durable and publicly acceptable. Strategies for activation and improvement of plant immunity aim at enhancing host’s capability of recognizing invading pathogens, boosting the executive arsenal of plant immunity, and interfering with virulence strategies employed by microbial pathogens. Major advances in our understanding of the molecular basis of plant immunity and of microbial infection strategies have opened new ways for engineering durable resistance in crop plants.
Book Synopsis Innate Immunity in Health and Disease by : Shailendra K. Saxena
Download or read book Innate Immunity in Health and Disease written by Shailendra K. Saxena and published by BoD – Books on Demand. This book was released on 2021-08-25 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book focuses on various aspects and properties of innate immunity, whose deep understanding is integral for safeguarding the human race from further loss of resources and economies due to innate immune response-mediated diseases. Throughout this book, we examine the individual mechanisms by which the innate immune response acts to protect the host from pathogenic infectious agents and other non-communicable diseases. Written by experts in the field, the volume discusses the significance of macrophages in infectious disease, tumor metabolism, and muscular disorders. Chapters cover such topics as the fate of differentiated macrophages and the molecular pathways that are important for the pathologic role of macrophages.
Book Synopsis Immunomodulation of Innate Immune Cells by : Catarina R. Almeida
Download or read book Immunomodulation of Innate Immune Cells written by Catarina R. Almeida and published by Frontiers Media SA. This book was released on 2020-03-23 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt:
