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Author : 李鴻禧
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (891 download)
Download or read book In Vivo Diffusion Magnetic Resonance Imaging to Evaluate Microstructure of the Human Brain written by 李鴻禧 and published by . This book was released on 2014 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Heidi Johansen-Berg
Publisher : Academic Press
ISBN 13 : 0080878512
Total Pages : 507 pages
Book Rating : 4.0/5 (88 download)
Download or read book Diffusion MRI written by Heidi Johansen-Berg and published by Academic Press. This book was released on 2009-04-28 with total page 507 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diffusion MRI is a magnetic resonance imaging (MRI) method that produces in vivo images of biological tissues weighted with the local microstructural characteristics of water diffusion, providing an effective means of visualizing functional connectivities in the nervous system. This book is the first comprehensive reference promoting the understanding of this rapidly evolving and powerful technology and providing the essential handbook for designing, analyzing or interpreting diffusion MR experiments.The book presents diffusion imaging in the context of well-established, classical experimental techniques, so that readers will be able to assess the scope and limitations of the new imaging technology with respect to techniques available previously. All chapters are written by leading international experts and cover methodology, validation of the imaging technology, application of diffusion imaging to the study of variation and development of normal brain anatomy, and disruption to the white matter in neurological disease or psychiatric disorder. • Discusses all aspects of a diffusion MRI study from acquisition, through analysis, to interpretation, providing an essential reference text for scientists designing or interpreting diffusion MR experiments• Practical advice on running an experiment• Full color throughout
Author : Maira Tariq
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (116 download)
Download or read book In Vivo Quantification of Complex Neurite Configurations Using Magnetic Resonance Imaging written by Maira Tariq and published by . This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Nicole Seiberlich
Publisher : Academic Press
ISBN 13 : 0128170581
Total Pages : 1094 pages
Book Rating : 4.1/5 (281 download)
Download or read book Quantitative Magnetic Resonance Imaging written by Nicole Seiberlich and published by Academic Press. This book was released on 2020-11-18 with total page 1094 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quantitative Magnetic Resonance Imaging is a ‘go-to’ reference for methods and applications of quantitative magnetic resonance imaging, with specific sections on Relaxometry, Perfusion, and Diffusion. Each section will start with an explanation of the basic techniques for mapping the tissue property in question, including a description of the challenges that arise when using these basic approaches. For properties which can be measured in multiple ways, each of these basic methods will be described in separate chapters. Following the basics, a chapter in each section presents more advanced and recently proposed techniques for quantitative tissue property mapping, with a concluding chapter on clinical applications. The reader will learn: The basic physics behind tissue property mapping How to implement basic pulse sequences for the quantitative measurement of tissue properties The strengths and limitations to the basic and more rapid methods for mapping the magnetic relaxation properties T1, T2, and T2* The pros and cons for different approaches to mapping perfusion The methods of Diffusion-weighted imaging and how this approach can be used to generate diffusion tensor maps and more complex representations of diffusion How flow, magneto-electric tissue property, fat fraction, exchange, elastography, and temperature mapping are performed How fast imaging approaches including parallel imaging, compressed sensing, and Magnetic Resonance Fingerprinting can be used to accelerate or improve tissue property mapping schemes How tissue property mapping is used clinically in different organs Structured to cater for MRI researchers and graduate students with a wide variety of backgrounds Explains basic methods for quantitatively measuring tissue properties with MRI - including T1, T2, perfusion, diffusion, fat and iron fraction, elastography, flow, susceptibility - enabling the implementation of pulse sequences to perform measurements Shows the limitations of the techniques and explains the challenges to the clinical adoption of these traditional methods, presenting the latest research in rapid quantitative imaging which has the possibility to tackle these challenges Each section contains a chapter explaining the basics of novel ideas for quantitative mapping, such as compressed sensing and Magnetic Resonance Fingerprinting-based approaches
Author : Heidi Johansen-Berg
Publisher : Academic Press
ISBN 13 : 0124055095
Total Pages : 627 pages
Book Rating : 4.1/5 (24 download)
Download or read book Diffusion MRI written by Heidi Johansen-Berg and published by Academic Press. This book was released on 2013-11-04 with total page 627 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diffusion MRI remains the most comprehensive reference for understanding this rapidly evolving and powerful technology and is an essential handbook for designing, analyzing, and interpreting diffusion MR experiments. Diffusion imaging provides a unique window on human brain anatomy. This non-invasive technique continues to grow in popularity as a way to study brain pathways that could never before be investigated in vivo. This book covers the fundamental theory of diffusion imaging, discusses its most promising applications to basic and clinical neuroscience, and introduces cutting-edge methodological developments that will shape the field in coming years. Written by leading experts in the field, it places the exciting new results emerging from diffusion imaging in the context of classical anatomical techniques to show where diffusion studies might offer unique insights and where potential limitations lie. Fully revised and updated edition of the first comprehensive reference on a powerful technique in brain imaging Covers all aspects of a diffusion MRI study from acquisition through analysis to interpretation, and from fundamental theory to cutting-edge developments New chapters covering connectomics, advanced diffusion acquisition, artifact removal, and applications to the neonatal brain Provides practical advice on running an experiment Includes discussion of applications in psychiatry, neurology, neurosurgery, and basic neuroscience Full color throughout
Author : Gaëtan Olivier D. Rensonnet
Publisher :
ISBN 13 :
Total Pages : 143 pages
Book Rating : 4.:/5 (112 download)
Download or read book In Vivo Diffusion Magnetic Resonance Imaging of the White Matter Microstructure from Dictionaries Generated by Monte Carlo Simulations written by Gaëtan Olivier D. Rensonnet and published by . This book was released on 2019 with total page 143 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mots-clés de l'auteur: diffusion-weighted magnetic resonance imaging ; white matter ; brain ; microstructure ; Monte Carlo simulations ; fingerprinting ; dictionaries.
Author : Paul Tofts
Publisher : John Wiley & Sons
ISBN 13 : 0470869496
Total Pages : 650 pages
Book Rating : 4.4/5 (78 download)
Download or read book Quantitative MRI of the Brain written by Paul Tofts and published by John Wiley & Sons. This book was released on 2005-08-19 with total page 650 pages. Available in PDF, EPUB and Kindle. Book excerpt: 2004 BMA Medical Book Competition Winner (Radiology category) “This is an exciting book, with a new approach to use of the MRI scanner. It bridges the gap between clinical research and general neuro-radiological practice. It is accessible to the clinical radiologist, and yet thorough in its treatment of the underlying physics and of the science of measurement. It is likely to become a classic.” British Medical Association This indispensable 'how to' manual of quantitative MR is essential for anyone who wants to use the gamut of modern quantitative methods to measure the effects of neurological disease, its progression, and its response to treatment. It contains both the methodology and clinical applications, reflecting the increasing interest in quantitative MR in studying disease and its progression. The editor is an MR scientist with an international reputation for high quality research The contributions are written jointly by MR physicists and MR clinicians, producing a practical book for both the research and medical communities A practical book for both the research and medical communities “Paul Tofts has succeeded brilliantly in capturing the essence of what needs to become the future of radiology in particular, and medicine in general – quantitative measurements of disease.” Robert I. Grossman, M.D. New York, University School of Medicine (from the Foreword)
Author : Julien Valette
Publisher : Frontiers Media SA
ISBN 13 : 2889458415
Total Pages : 193 pages
Book Rating : 4.8/5 (894 download)
Download or read book Assessing Cellular Microstructure in Biological Tissues using In Vivo Diffusion-Weighted Magnetic Resonance written by Julien Valette and published by Frontiers Media SA. This book was released on 2019-05-16 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetic resonance imaging (MRI) and spectroscopy (MRS) techniques have opened new doors for examining biological tissues in vivo. By combining sensitization to diffusion using magnetic field gradients with a variety of imaging and localization schemes, diffusion-weighted MRI and diffusion-weighted MRS allow investigating translational diffusion of endogenous molecules, such as water or metabolites, in biological tissues, most commonly the brain but also other organs such as the prostate. The typical voxel resolution of MRI or MRS is in the millimeter to centimeter range, much lower than the cellular scale. However, as molecules are typically diffusing over just a few µm during the duration of the measurement (the “diffusion time”) and encounter numerous biological membranes at these scales, the average cellular microstructure has a critical influence on the measured diffusion signal. Hence, diffusion-weighted MRI and diffusion-weighted MRS are sensitive to tissue microstructure at a scale well below the nominal imaging resolution. However, the connection between diffusion properties and tissue microstructure remains indirect, so any attempt to quantify microstructure will rely on modeling. The goal of this Research Topic was to gather experts in various acquisition and modeling strategies and show how these approaches, despite their own strengths and weaknesses, can yield unique information about cellular microstructure, and sometimes complement each other.
Author : Nathan S. White
Publisher :
ISBN 13 :
Total Pages : 129 pages
Book Rating : 4.:/5 (525 download)
Download or read book Quantitative Diffusion Magnetic Resonance Imaging of the Brain written by Nathan S. White and published by . This book was released on 2010 with total page 129 pages. Available in PDF, EPUB and Kindle. Book excerpt: Owing to its exquisitely sensitive contrast mechanism, diffusion magnetic resonance imaging is a powerful non-invasive approach for studying the microstructural properties of the human brain in vivo. Magnetic resonance images are made sensitive to the microscopic displacements of water molecules that take place in brain tissue as part of the natural, physical diffusion process. Tissue water is used as an intrinsic probe, revealing important clues into the subtle architectural features of normal and pathologic brain tissue. Typical inferences include the intravoxel orientation distribution of neuronal fibers and changes in diffusion resulting from cell swelling in acute stroke. However, despite the many important advances made in the field of diffusion magnetic resonance imaging over the past decade, quantitative inference in the human brain remains somewhat limited due to the lack of direct quantitative validation against realistic biological architectures and practical limitations in data collection due to sub-optimal design parameters and artifacts caused by patient motion during scanning. In addition, current methods to resolve neuronal fiber orientations are unable to disambiguate fiber structures at different microscopic length (size) scales. In this dissertation I present a series of studies addressing each of these important limitations, starting with a general real-time image-based technique for motion correction in magnetic resonance images and ending with a series of studies on inferring complex fiber orientations from diffusion data, addressing issues such as quantitative histological validation, optimal acquisition, and improved multi-scale analysis.
Author : Andrea Fuster
Publisher : Springer
ISBN 13 : 3319285882
Total Pages : 236 pages
Book Rating : 4.3/5 (192 download)
Download or read book Computational Diffusion MRI written by Andrea Fuster and published by Springer. This book was released on 2016-04-08 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: These Proceedings of the 2015 MICCAI Workshop “Computational Diffusion MRI” offer a snapshot of the current state of the art on a broad range of topics within the highly active and growing field of diffusion MRI. The topics vary from fundamental theoretical work on mathematical modeling, to the development and evaluation of robust algorithms, new computational methods applied to diffusion magnetic resonance imaging data, and applications in neuroscientific studies and clinical practice. Over the last decade interest in diffusion MRI has exploded. The technique provides unique insights into the microstructure of living tissue and enables in-vivo connectivity mapping of the brain. Computational techniques are key to the continued success and development of diffusion MRI and to its widespread transfer into clinical practice. New processing methods are essential for addressing issues at each stage of the diffusion MRI pipeline: acquisition, reconstruction, modeling and model fitting, image processing, fiber tracking, connectivity mapping, visualization, group studies and inference. This volume, which includes both careful mathematical derivations and a wealth of rich, full-color visualizations and biologically or clinically relevant results, offers a valuable starting point for anyone interested in learning about computational diffusion MRI and mathematical methods for mapping brain connectivity, as well as new perspectives and insights on current research challenges for those currently working in the field. It will be of interest to researchers and practitioners in the fields of computer science, MR physics, and applied mathematics.
Author : Evren Özarslan
Publisher : Springer Nature
ISBN 13 : 3030562158
Total Pages : 284 pages
Book Rating : 4.0/5 (35 download)
Download or read book Anisotropy Across Fields and Scales written by Evren Özarslan and published by Springer Nature. This book was released on 2021 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book focuses on processing, modeling, and visualization of anisotropy information, which are often addressed by employing sophisticated mathematical constructs such as tensors and other higher-order descriptors. It also discusses adaptations of such constructs to problems encountered in seemingly dissimilar areas of medical imaging, physical sciences, and engineering. Featuring original research contributions as well as insightful reviews for scientists interested in handling anisotropy information, it covers topics such as pertinent geometric and algebraic properties of tensors and tensor fields, challenges faced in processing and visualizing different types of data, statistical techniques for data processing, and specific applications like mapping white-matter fiber tracts in the brain. The book helps readers grasp the current challenges in the field and provides information on the techniques devised to address them. Further, it facilitates the transfer of knowledge between different disciplines in order to advance the research frontiers in these areas. This multidisciplinary book presents, in part, the outcomes of the seventh in a series of Dagstuhl seminars devoted to visualization and processing of tensor fields and higher-order descriptors, which was held in Dagstuhl, Germany, on October 28-November 2, 2018.
Author : Susumu Mori
Publisher : Academic Press
ISBN 13 : 0123984076
Total Pages : 141 pages
Book Rating : 4.1/5 (239 download)
Download or read book Introduction to Diffusion Tensor Imaging written by Susumu Mori and published by Academic Press. This book was released on 2013-08-02 with total page 141 pages. Available in PDF, EPUB and Kindle. Book excerpt: The concepts behind diffusion tensor imaging (DTI) are commonly difficult to grasp, even for magnetic resonance physicists. To make matters worse, a many more complex higher-order methods have been proposed over the last few years to overcome the now well-known deficiencies of DTI. In Introduction to Diffusion Tensor Imaging: And Higher Order Models, these concepts are explained through extensive use of illustrations rather than equations to help readers gain a more intuitive understanding of the inner workings of these techniques. Emphasis is placed on the interpretation of DTI images and tractography results, the design of experiments, and the types of application studies that can be undertaken. Diffusion MRI is a very active field of research, and theories and techniques are constantly evolving. To make sense of this constantly shifting landscape, there is a need for a textbook that explains the concepts behind how these techniques work in a way that is easy and intuitive to understand—Introduction to Diffusion Tensor Imaging fills this gap. Extensive use of illustrations to explain the concepts of diffusion tensor imaging and related methods Easy to understand, even without a background in physics Includes sections on image interpretation, experimental design, and applications Up-to-date information on more recent higher-order models, which are increasingly being used for clinical applications
Author : Derek K Jones
Publisher : Oxford University Press
ISBN 13 : 0199708703
Total Pages : 784 pages
Book Rating : 4.1/5 (997 download)
Download or read book Diffusion MRI written by Derek K Jones and published by Oxford University Press. This book was released on 2010-11-11 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt: Professor Derek Jones, a world authority on diffusion MRI, has assembled most of the world's leading scientists and clinicians developing and applying diffusion MRI to produce an authorship list that reads like a "Who's Who" of the field and an essential resource for those working with diffusion MRI. Destined to be a modern classic, this definitive and richly illustrated work covers all aspects of diffusion MRI from basic theory to clinical application. Oxford Clinical Neuroscience is a comprehensive, cross-searchable collection of resources offering quick and easy access to eleven of Oxford University Press's prestigious neuroscience texts. Joining Oxford Medicine Online these resources offer students, specialists and clinical researchers the best quality content in an easy-to-access format.
Author : Madan M Kaila
Publisher : Elsevier
ISBN 13 : 0123847125
Total Pages : 517 pages
Book Rating : 4.1/5 (238 download)
Download or read book Quantum Magnetic Resonance Imaging Diagnostics of Human Brain Disorders written by Madan M Kaila and published by Elsevier. This book was released on 2010-06-21 with total page 517 pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetic resonance imaging (MRI) is a medical imaging technique used to visualize detailed internal structure of the body. This book discusses the recent developments in the field of MRI and its application to the diagnosis of human brain disorders. In addition, it reviews the newly emerging concepts and technology, based on the multi-coherence imaging (MQCI). It explains how computer packages can be used to generate images in diseased states and compare them to in vivo results. This will help improve the diagnosis of brain disorders based on the real-time events happening on atomic and molecular quantum levels. This is important since quantum-based MRI would enable clinicians to detect brain tumors at the very early stages. Uses practical examples to explain the techniques - making it easier to understand the concepts Uses diagrams to explain the physics behind the technique - avoiding the use of complicated mathematical formulae
Author : Guglielmo Genovese
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (123 download)
Download or read book Evaluation of Microstructural Alterations in the Human Brain and in Experimental Models with Diffusion-weighted Magnetic Resonance Spectroscopy written by Guglielmo Genovese and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diffusion-weighted magnetic resonance spectroscopy (DW-MRS) is a unique tool to investigate brain microstructure in a cell-specific manner, while neglecting phenomena related to the extracellular environment. In this thesis, we studied DW-MRS in several complementary ways in order to be able to apply this technique in later clinical studies: optimization of the acquisition pipeline and data analysis, reproducibility of the diffusion measures, and histological validation of the DW-MRS metrics as potential useful markers of brain diseases-related microstructural alterations. The thesis is composed of three parts. In the first part, we propose an optimization of the acquisition and of the post-processing procedures for single-voxel DW-MRS experiments in humans, and an evaluation of the feasibility of a DW-semi-LASER sequence for clinical studies at 3 T. Power calculations for the metabolite diffusion measures were reported in order to provide useful information for designing case-control studies in patients with brain diseases. In the second part, we focused on validating DW-MRS metrics using histological measures in two different mouse models of myelinopathy. A strong correlation was found between mIns diffusivity and the astrocyte area fraction confirming the hypothesis that mIns diffusivity can be used as a marker of astrocyte hypertrophy during the inflammatory process. In the last part, we studied the longitudinal evolution of axonal and glial alterations after ischemic stroke in the human brain. We observed the presence of inflammation due to glial reactivity about one month after ischemic stroke and astrocytic reactivity up to about three months after the ischemic stroke.
Author : Florian Beissner
Publisher : Frontiers E-books
ISBN 13 : 2889192474
Total Pages : 93 pages
Book Rating : 4.8/5 (891 download)
Download or read book Investigating the human brainstem with structural and functional MRI written by Florian Beissner and published by Frontiers E-books. This book was released on 2014-07-30 with total page 93 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brainstem is one of the least understood parts of the human brain despite its prime importance for the maintenance of basic vital functions. Owing to its role as a relay station between spinal cord, cerebellum and neocortex, the brainstem contains vital nodes of all functional systems in the central nervous system, including the visual, auditory, gustatory, vestibular, somatic and visceral senses, and the somatomotor as well as autonomic nervous systems. While the brainstem has been extensively studied in animals using invasive methods, human studies remain scarce. Magnetic resonance imaging (MRI) as a non-invasive and widely available method is one possibility to access the brainstem in humans and measure its structure as well as function. The close vicinity of the brainstem to large arteries and ventricles and the small size of the anatomical structures, however, place high demands on imaging as well as data analysis methods. Nevertheless, the field of brainstem-(f)MRI has significantly advanced in the past few years, largely due to the development of several new tools that facilitate studying this critical part of the human brain. Within this scope, the goal of this Research Topic is to compile work representing the state of the art in functional and structural MRI of the human brainstem.
Author : Valentino Braitenberg
Publisher : Springer Science & Business Media
ISBN 13 : 3662037335
Total Pages : 243 pages
Book Rating : 4.6/5 (62 download)
Download or read book Cortex: Statistics and Geometry of Neuronal Connectivity written by Valentino Braitenberg and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: By means of quantitative analysis of the tissue components in the cortex of the mouse, this book presents an overall picture of the cortical network which is then related to various theories on cortical function. Centering around the idea of a diffuse network in a fairly homogeneous population of excitatory neurons, that of the pyramidal cells, it shows that the whole organisation in the cortical skeleton of pryramidal cells corresponds well with the idea of an associative memory and with the theory of cell assemblies. Provides the reader with information on quantitative neuroanatomy and also on the methods used, in particular those that vary from the norm.
