In Vitro Studies of the Biochemical Toxicity of Perfluorooctane Sulfonic Acid and Its Possible Interaction with 2,3,7,8-tetrachlorodibenzo-p-dioxin

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Publisher :
ISBN 13 :
Total Pages : 164 pages
Book Rating : 4.3/5 (129 download)

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Book Synopsis In Vitro Studies of the Biochemical Toxicity of Perfluorooctane Sulfonic Acid and Its Possible Interaction with 2,3,7,8-tetrachlorodibenzo-p-dioxin by : Wen Yue Hu

Download or read book In Vitro Studies of the Biochemical Toxicity of Perfluorooctane Sulfonic Acid and Its Possible Interaction with 2,3,7,8-tetrachlorodibenzo-p-dioxin written by Wen Yue Hu and published by . This book was released on 2000 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Wildlife Ecotoxicology

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Publisher : Springer Science & Business Media
ISBN 13 : 0387894322
Total Pages : 476 pages
Book Rating : 4.3/5 (878 download)

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Book Synopsis Wildlife Ecotoxicology by : John E. Elliott

Download or read book Wildlife Ecotoxicology written by John E. Elliott and published by Springer Science & Business Media. This book was released on 2011-08-27 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many books have now been published in the broad field of environmental toxicology. However, to date, none of have presented the often fascinating stories of the wildlife science, and the steps along the way from discovery of problems caused by environmental pollutants to the regulatory and non-regulatory efforts to address the problems. This book provides case by case examinations of how toxic chemical effects on wildlife have brought about policy and regulatory decisions, and positive changes in environmental conditions. Wild animal stories, whether they are about the disappearance of charismatic top predators, or of grossly deformed embryos or frogs, provide powerful symbols that can and have captured the public's imagination and have resulted in increased awareness by decision makers. It is the intent of this book to present factual and balanced overviews and summaries of the science and the subsequent regulatory processes that followed to effect change (or not). We cover a variety of chemicals and topics beginning with an update of the classic California coastal DDT story of eggshell thinning and avian reproduction to more recent cases, such as the veterinarian pharmaceutical that has brought three species of Asian vultures to the brink of extinction. Researchers, regulators, educators, NGOs and the general public will find valuable insights into the processes and mechanisms involved both in environmental scientific investigation and in efforts to effect positive change.

Molecular, Clinical and Environmental Toxicology

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Publisher : Springer Science & Business Media
ISBN 13 : 3764383402
Total Pages : 580 pages
Book Rating : 4.7/5 (643 download)

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Book Synopsis Molecular, Clinical and Environmental Toxicology by : Andreas Luch

Download or read book Molecular, Clinical and Environmental Toxicology written by Andreas Luch and published by Springer Science & Business Media. This book was released on 2012-06-07 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: Environmental Toxicology is the third volume of a three-volume set on molecular, clinical and environmental toxicology that offers a comprehensive and in-depth response to the increasing importance and abundance of chemicals of daily life. By providing intriguing insights far down to the molecular level, this three-volume work covers the entire range of modern toxicology with special emphasis on recent developments and achievements. It is written for students and professionals in medicine, science, public health or engineering who are demanding reliable information on toxic or potentially harmful agents and their adverse effects on the human body.

Global Risk-Based Management of Chemical Additives II

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Publisher : Springer
ISBN 13 : 9783642345715
Total Pages : 478 pages
Book Rating : 4.3/5 (457 download)

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Book Synopsis Global Risk-Based Management of Chemical Additives II by : Bernd Bilitewski

Download or read book Global Risk-Based Management of Chemical Additives II written by Bernd Bilitewski and published by Springer. This book was released on 2013-02-25 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemical additives are used to enhance the properties of many industrial products. Since their release into the environment is a potential risk for man and nature, their fate and behavior have been investigated in the framework of the European Union-funded project RISKCYCLE. The results are presented in two volumes, Global Risk-Based Management of Chemical Additives I: Production, Usage and Environmental Occurrence and Global Risk-Based Management of Chemical Additives II: Risk-Based Assessment and Management Strategies. This book is the second of the two volumes and features two main parts. In the first part, experts in the field discuss different models related to the assessment of the potential risks posed by chemical additives and analyze their benefits and drawbacks. In the second part, specific case studies in which the models have been applied are presented and the reliability of the models is evaluated. This volume is an invaluable source of information for scientists and governmental agencies dealing with the risk assessment of chemicals on a global scale.

The EU Water Framework Directive

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Publisher : IWA Publishing
ISBN 13 : 9781900222129
Total Pages : 226 pages
Book Rating : 4.2/5 (221 download)

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Book Synopsis The EU Water Framework Directive by : P. Chave

Download or read book The EU Water Framework Directive written by P. Chave and published by IWA Publishing. This book was released on 2001-09-30 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Taking over 10 years to develop, the new EU Water Framework Directive is the most significant legal instrument in the water field to emerge from Brussels for some time and will have a profound effect on how water is managed in Europe over the next 25 years. The book outlines its basic features. It explains how the current approach to water management will have to change in order that European Member states and those countries currently in accession negotiations can meet the requirements of the directive, describing a number of examples of current practices as possible systems which could be used in the new approach. The concept of river basin management is outlined, and the potential institutional problems associated with implementing such a system are discussed including the problems associated with cross-border river basins, a common situation in Europe. Examples of existing river basin authorities and international collaboration are given as possible models. The directive requires the establishment of programmes of measures to improve water status. Some countries already use such a concept, and examples are quoted. As a result of its implementation, the directive aims to achieve good water status in all natural surface waters and groundwater in 15 years. For surface waters, the definition of 'good' is based on a new concept of 'ecological quality' taking into account biology, chemistry and their physical features. For groundwater, it includes quantitative status. The approach taken is an integrated one which has to consider all the naturally occurring and human factors which affect the waters. The difficulties of interpretation of the new concept of 'ecological water status' are discussed and some of the examples of current biological and chemical classification schemes that are used in Europe are examined. The directive also alters the way in which pollution is to be controlled - the 'combined' approach. This concept is explained. The EU Water Framework Directive: An Introduction is an invaluable source of guidance on the implementation of the Water Framework Directive for all those concerned with water management including water quality planners and scientists, pollution control and environmental staff in the water and wastewater industries and environmental regulators who all have to adapt to the new approach to their work. Contents Introduction The EU Water Framework Directive Principal Obligations of the Directive Implementation of the Directive River Basin Districts River Basin Characteristics Environmental Objectives Programme of Measures River Basin Plans Groundwater Waters Requiring Special Protection Priority Substances Monitoring Economic Instruments Recording and Reporting Summary Timescales and Future Developments

Reviews of Environmental Contamination and Toxicology Volume 213

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Publisher : Springer Science & Business Media
ISBN 13 : 1441998608
Total Pages : 176 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Reviews of Environmental Contamination and Toxicology Volume 213 by : David M. Whitacre

Download or read book Reviews of Environmental Contamination and Toxicology Volume 213 written by David M. Whitacre and published by Springer Science & Business Media. This book was released on 2011-05-04 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reviews of Environmental Contamination and Toxicology attempts to provide concise, critical reviews of timely advances, philosophy and significant areas of accomplished or needed endeavor in the total field of xenobiotics, in any segment of the environment, as well as toxicological implications.

Toxicologic Pathology

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Publisher : CRC Press
ISBN 13 : 1439872120
Total Pages : 987 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Toxicologic Pathology by : Pritam S. Sahota

Download or read book Toxicologic Pathology written by Pritam S. Sahota and published by CRC Press. This book was released on 2013-04-09 with total page 987 pages. Available in PDF, EPUB and Kindle. Book excerpt: As drug development shifts over time to address unmet medical needs and more targeted therapies are developed, previously unseen pharmacological or off-target effects may occur in treatment. Designed to provide practical information for the bench toxicologic pathologist working in pharmaceutical drug research, Toxicologic Pathology: Nonclinical Saf

Translational Toxicology

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Publisher : Humana Press
ISBN 13 : 331927449X
Total Pages : 384 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Translational Toxicology by : Claude L. Hughes

Download or read book Translational Toxicology written by Claude L. Hughes and published by Humana Press. This book was released on 2016-03-23 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bringing together a distinguished interdisciplinary team of contributors, this volume provides a comprehensive exploration of translational toxicology—a systematic approach to developing therapeutic interventions that can protect against, mitigate, or reverse the effects of exposures. In particular, the book addresses modes of action and biomarkers, developmental risks of exposures, and potential translational toxicology therapeutics. The result is a compelling application of developmental toxicology in a new therapeutic discipline that is destined to become part of standard medical practice. Translational Toxicology: Defining a New Therapeutic Discipline is an essential text for regulatory authorities, scientists, and physicians who are concerned with environmental exposures, public health, nutrition, and pharmaceutical research and development. Basic science, epidemiological, and clinical investigators will also find this book a significant resource.

A Comprehensive Guide to Toxicology in Preclinical Drug Development

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Publisher : Academic Press
ISBN 13 : 0123878160
Total Pages : 903 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis A Comprehensive Guide to Toxicology in Preclinical Drug Development by : Ali S. Faqi

Download or read book A Comprehensive Guide to Toxicology in Preclinical Drug Development written by Ali S. Faqi and published by Academic Press. This book was released on 2012-10-18 with total page 903 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Comprehensive Guide to Toxicology in Preclinical Drug Development is a resource for toxicologists in industry and regulatory settings, as well as directors working in contract resource organizations, who need a thorough understanding of the drug development process. Incorporating real-life case studies and examples, the book is a practical guide that outlines day-to-day activities and experiences in preclinical toxicology. This multi-contributed reference provides a detailed picture of the complex and highly interrelated activities of preclinical toxicology in both small molecules and biologics. The book discusses discovery toxicology and the international guidelines for safety evaluation, and presents traditional and nontraditional toxicology models. Chapters cover development of vaccines, oncology drugs, botanic drugs, monoclonal antibodies, and more, as well as study development and personnel, the role of imaging in preclinical evaluation, and supporting materials for IND applications. By incorporating the latest research in this area and featuring practical scenarios, this reference is a complete and actionable guide to all aspects of preclinical drug testing. - Chapters written by world-renowned contributors who are experts in their fields - Includes the latest research in preclinical drug testing and international guidelines - Covers preclinical toxicology in small molecules and biologics in one single source

Principles of Toxicology

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Publisher : John Wiley & Sons
ISBN 13 : 0471459232
Total Pages : 625 pages
Book Rating : 4.4/5 (714 download)

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Book Synopsis Principles of Toxicology by : Phillip L. Williams

Download or read book Principles of Toxicology written by Phillip L. Williams and published by John Wiley & Sons. This book was released on 2003-10-10 with total page 625 pages. Available in PDF, EPUB and Kindle. Book excerpt: A fully updated and expanded edition of the bestselling guide on toxicology and its practical application The field of toxicology has grown enormously since Industrial Toxicology: Safety and Health Applications in the Workplace was first published in 1985. And while the original edition was hugely popular among occupational health professionals, the time is ripe to address toxic agents not only in the industrial setting but also in the environment at large. Renamed Principles of Toxicology: Environmental and Industrial Applications, this new edition provides health protection professionals as well as environmental scientists with precise, up-to-date, practical information on how to apply the science of toxicology in both the occupational and environmental setting. Through contributions from leading experts in diverse fields, Principles of Toxicology, Second Edition features: Clear explanations of the fundamentals necessary for an understanding of the effects of chemical hazards on human health and ecosystems Coverage of occupational medicine and epidemiological issues The manifestation of toxic agents such as metals, pesticides, organic solvents, and natural toxins Special emphasis on the evaluation and control of toxic hazards Specific case histories on applying risk assessment methods in the modern workplace Ample figures, references, and a comprehensive glossary of toxicological terms

State of the Great Lakes, 2009

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Publisher :
ISBN 13 :
Total Pages : 16 pages
Book Rating : 4.:/5 (891 download)

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Book Synopsis State of the Great Lakes, 2009 by :

Download or read book State of the Great Lakes, 2009 written by and published by . This book was released on 2009 with total page 16 pages. Available in PDF, EPUB and Kindle. Book excerpt:

NS&T Program

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Publisher :
ISBN 13 :
Total Pages : 36 pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis NS&T Program by :

Download or read book NS&T Program written by and published by . This book was released on 1998 with total page 36 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Exposure Assessment in Environmental Epidemiology

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Publisher : Oxford University Press, USA
ISBN 13 : 0199378789
Total Pages : 417 pages
Book Rating : 4.1/5 (993 download)

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Book Synopsis Exposure Assessment in Environmental Epidemiology by : Mark J. Nieuwenhuijsen

Download or read book Exposure Assessment in Environmental Epidemiology written by Mark J. Nieuwenhuijsen and published by Oxford University Press, USA. This book was released on 2015 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: This completely updated edition of Exposure Assessment in Environmental Epidemiology offers a practical introduction to exposure assessment methodologies in environmental epidemiologic studies. In addition to methods for traditional methods -- questionnaires, biomonitoring -- this new edition is expanded to include geographic information systems, modeling, personal sensoring, remote sensing, and OMICs technologies. In addition, each of these methods is contextualized within a recent epidemiology study, maximizing illustration for students and those new to these to these techniques. With clear writing and extensive illustration, this book will be useful to anyone interested in exposure assessment, regardless of background.

Exposure Science in the 21st Century

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Publisher : National Academies Press
ISBN 13 : 0309264685
Total Pages : 210 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Exposure Science in the 21st Century by : National Research Council

Download or read book Exposure Science in the 21st Century written by National Research Council and published by National Academies Press. This book was released on 2012-10-28 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: From the use of personal products to our consumption of food, water, and air, people are exposed to a wide array of agents each day-many with the potential to affect health. Exposure Science in the 21st Century: A Vision and A Strategy investigates the contact of humans or other organisms with those agents (that is, chemical, physical, and biologic stressors) and their fate in living systems. The concept of exposure science has been instrumental in helping us understand how stressors affect human and ecosystem health, and in efforts to prevent or reduce contact with harmful stressors. In this way exposure science has played an integral role in many areas of environmental health, and can help meet growing needs in environmental regulation, urban and ecosystem planning, and disaster management. Exposure Science in the 21st Century: A Vision and A Strategy explains that there are increasing demands for exposure science information, for example to meet needs for data on the thousands of chemicals introduced into the market each year, and to better understand the health effects of prolonged low-level exposure to stressors. Recent advances in tools and technologies-including sensor systems, analytic methods, molecular technologies, computational tools, and bioinformatics-have provided the potential for more accurate and comprehensive exposure science data than ever before. This report also provides a roadmap to take advantage of the technologic innovations and strategic collaborations to move exposure science into the future.

Environmental Contaminants in Biota

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Publisher : CRC Press
ISBN 13 : 1420084062
Total Pages : 750 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Environmental Contaminants in Biota by : W. Nelson Beyer

Download or read book Environmental Contaminants in Biota written by W. Nelson Beyer and published by CRC Press. This book was released on 2011-02-23 with total page 750 pages. Available in PDF, EPUB and Kindle. Book excerpt: Examining tissue residues of contaminants in biota reveals the movement of contaminants within organisms and through food chains as well as the context for understanding and quantifying injuries to organisms and their communities. Yet tissue concentrations of some contaminants are especially challenging to interpret and the ability of today’s analytical chemists to provide reliable analytical data of most important environmental contaminants often surpasses the ability of ecotoxicologists to interpret those data. Offering guidance on the ecotoxicologically meaningful interpretation of tissue concentrations, Environmental Contaminants in Biota, Interpreting Tissue Concentrations, Second Edition is updated with current data and new ways of analyzing those data as well as additional contaminants not previously considered. Beginning with a history of wildlife toxicology and data interpretation, chapters cover a wide range of contaminants and their hazardous and lethal concentrations in various animals including DDT, Dioxins, PCBs, and PBDEs in aquatic organisms; methylmurcury, selenium, and trace metals in fishes and aquatic invertebrates; and pharmaceuticals and organic contaminants in marine mammals. The book considers the impact of Polychlorinated Biphenyls, Dibenzo-p-Dioxins and Dibenzofurans, and Polybrominated Diphenyl Ethers; cyclodiene; and other organochlorine pesticides in birds and mammals. Later chapters examine the effects and analysis of lead, cadmium, and radionuclides in biota. With thousands of published research papers reporting tissue concentrations each year, Environmental Contaminants in Biota, Interpreting Tissue Concentrations, Second Edition gives ecotoxicologists the ability to draw actionable value regarding the toxicological consequences of those concentrations and relate tissue concentrations quantitatively to injury: the core of ecotoxicology.

Perfluoroalkyl Substances in the Environment

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Publisher : CRC Press
ISBN 13 : 0429945027
Total Pages : 495 pages
Book Rating : 4.4/5 (299 download)

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Book Synopsis Perfluoroalkyl Substances in the Environment by : David M. Kempisty

Download or read book Perfluoroalkyl Substances in the Environment written by David M. Kempisty and published by CRC Press. This book was released on 2018-08-06 with total page 495 pages. Available in PDF, EPUB and Kindle. Book excerpt: Per- and polyfluorinated alkyl substances (PFAS), often referred to as per- (and poly) fluorinated compounds (PFCs), have been used for years in many everyday3⁄4 and some lifesaving3⁄4 products. However, their use has been linked to adverse health effects in humans, a problem compounded by their persistence in the environment. This book discusses the various challenges of PFAS in our environment today, including their historical use as well as their chemical and toxicological properties. It also presents robust discussion of analytical challenges and special considerations in sampling. The work goes on to give practical recommendations for dealing with these compounds in today's dynamic regulatory landscape and includes several chapters on various remediation techniques. Key Features: Comprehensive overview of per- and polyfluorinated alkyl substances (PFAS) historical use and chemical/physical properties which help us understand their persistence, transport, and transformation pathways in the environment In-depth analysis of PFAS toxicology Detailed descriptions of conventional and state-of-the-art remediation technologies Practical recommendations for dealing with PFAS in a dynamic regulatory landscape Robust discussion of important sampling and analytical considerations Perfluoroalkyl Substances in the Environment: Theory, Practice, and Innovation explores the challenges across the topical areas of regulation and management, toxicology, environmental remediation, and analytical sampling and analysis.Readers will find this text helpful in understanding complexities associated with PFAS and informing management strategies to effectively protect this and future generations.

EPA-100-B.

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Publisher :
ISBN 13 :
Total Pages : 74 pages
Book Rating : 4.E/5 ( download)

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Book Synopsis EPA-100-B. by :

Download or read book EPA-100-B. written by and published by . This book was released on 2001 with total page 74 pages. Available in PDF, EPUB and Kindle. Book excerpt: