In Search of Mechanisms

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Author :
Publisher : University of Chicago Press
ISBN 13 : 022603982X
Total Pages : 251 pages
Book Rating : 4.2/5 (26 download)

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Book Synopsis In Search of Mechanisms by : Carl F. Craver

Download or read book In Search of Mechanisms written by Carl F. Craver and published by University of Chicago Press. This book was released on 2013-10-03 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroscientists investigate the mechanisms of spatial memory. Molecular biologists study the mechanisms of protein synthesis and the myriad mechanisms of gene regulation. Ecologists study nutrient cycling mechanisms and their devastating imbalances in estuaries such as the Chesapeake Bay. In fact, much of biology and its history involves biologists constructing, evaluating, and revising their understanding of mechanisms. With In Search of Mechanisms, Carl F. Craver and Lindley Darden offer both a descriptive and an instructional account of how biologists discover mechanisms. Drawing on examples from across the life sciences and through the centuries, Craver and Darden compile an impressive toolbox of strategies that biologists have used and will use again to reveal the mechanisms that produce, underlie, or maintain the phenomena characteristic of living things. They discuss the questions that figure in the search for mechanisms, characterizing the experimental, observational, and conceptual considerations used to answer them, all the while providing examples from the history of biology to highlight the kinds of evidence and reasoning strategies employed to assess mechanisms. At a deeper level, Craver and Darden pose a systematic view of what biology is, of how biology makes progress, of how biological discoveries are and might be made, and of why knowledge of biological mechanisms is important for the future of the human species.

In Search of the Causes of Evolution

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Author :
Publisher : Princeton University Press
ISBN 13 : 0691146950
Total Pages : 410 pages
Book Rating : 4.6/5 (911 download)

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Book Synopsis In Search of the Causes of Evolution by : Peter R. Grant

Download or read book In Search of the Causes of Evolution written by Peter R. Grant and published by Princeton University Press. This book was released on 2010-11-21 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: Evolutionary biology has witnessed breathtaking advances in recent years. Some of its most exciting insights have come from the crossover of disciplines as varied as paleontology, molecular biology, ecology, and genetics. This book brings together many of today's pioneers in evolutionary biology to describe the latest advances and explain why a cross-disciplinary and integrated approach to research questions is so essential. Contributors discuss the origins of biological diversity, mechanisms of evolutionary change at the molecular and developmental levels, morphology and behavior, and the ecology of adaptive radiations and speciation. They highlight the mutual dependence of organisms and their environments, and reveal the different strategies today's researchers are using in the field and laboratory to explore this interdependence. Peter and Rosemary Grant--renowned for their influential work on Darwin's finches in the Galápagos--provide concise introductions to each section and identify the key questions future research needs to address. In addition to the editors, the contributors are Myra Awodey, Christopher N. Balakrishnan, Rowan D. H. Barrett, May R. Berenbaum, Paul M. Brakefield, Philip J. Currie, Scott V. Edwards, Douglas J. Emlen, Joshua B. Gross, Hopi E. Hoekstra, Richard Hudson, David Jablonski, David T. Johnston, Mathieu Joron, David Kingsley, Andrew H. Knoll, Mimi A. R. Koehl, June Y. Lee, Jonathan B. Losos, Isabel Santos Magalhaes, Albert B. Phillimore, Trevor Price, Dolph Schluter, Ole Seehausen, Clifford J. Tabin, John N. Thompson, and David B. Wake.

Evaluating Evidence of Mechanisms in Medicine

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Author :
Publisher : Springer
ISBN 13 : 3319946102
Total Pages : 131 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis Evaluating Evidence of Mechanisms in Medicine by : Veli-Pekka Parkkinen

Download or read book Evaluating Evidence of Mechanisms in Medicine written by Veli-Pekka Parkkinen and published by Springer. This book was released on 2018-07-13 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is open access under a CC BY license. This book is the first to develop explicit methods for evaluating evidence of mechanisms in the field of medicine. It explains why it can be important to make this evidence explicit, and describes how to take such evidence into account in the evidence appraisal process. In addition, it develops procedures for seeking evidence of mechanisms, for evaluating evidence of mechanisms, and for combining this evaluation with evidence of association in order to yield an overall assessment of effectiveness. Evidence-based medicine seeks to achieve improved health outcomes by making evidence explicit and by developing explicit methods for evaluating it. To date, evidence-based medicine has largely focused on evidence of association produced by clinical studies. As such, it has tended to overlook evidence of pathophysiological mechanisms and evidence of the mechanisms of action of interventions. The book offers a useful guide for all those whose work involves evaluating evidence in the health sciences, including those who need to determine the effectiveness of health interventions and those who need to ascertain the effects of environmental exposures.

The Routledge Handbook of Mechanisms and Mechanical Philosophy

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Author :
Publisher : Taylor & Francis
ISBN 13 : 131755230X
Total Pages : 495 pages
Book Rating : 4.3/5 (175 download)

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Book Synopsis The Routledge Handbook of Mechanisms and Mechanical Philosophy by : Stuart Glennan

Download or read book The Routledge Handbook of Mechanisms and Mechanical Philosophy written by Stuart Glennan and published by Taylor & Francis. This book was released on 2017-07-06 with total page 495 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientists studying the burning of stars, the evolution of species, DNA, the brain, the economy, and social change, all frequently describe their work as searching for mechanisms. Despite this fact, for much of the twentieth century philosophical discussions of the nature of mechanisms remained outside philosophy of science. The Routledge Handbook of Mechanisms and Mechanical Philosophy is an outstanding reference source to the key topics, problems, and debates in this exciting subject and is the first collection of its kind. Comprising over thirty chapters by a team of international contributors, the Handbook is divided into four Parts: Historical perspectives on mechanisms The nature of mechanisms Mechanisms and the philosophy of science Disciplinary perspectives on mechanisms. Within these Parts central topics and problems are examined, including the rise of mechanical philosophy in the seventeenth century; what mechanisms are made of and how they are organized; mechanisms and laws and regularities; how mechanisms are discovered and explained; dynamical systems theory; and disciplinary perspectives from physics, chemistry, biology, biomedicine, ecology, neuroscience, and the social sciences. Essential reading for students and researchers in philosophy of science, the Handbook will also be of interest to those in related fields, such as metaphysics, philosophy of psychology, and history of science.

Making Things Move DIY Mechanisms for Inventors, Hobbyists, and Artists

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Author :
Publisher : McGraw Hill Professional
ISBN 13 : 0071741682
Total Pages : 369 pages
Book Rating : 4.0/5 (717 download)

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Book Synopsis Making Things Move DIY Mechanisms for Inventors, Hobbyists, and Artists by : Dustyn Roberts

Download or read book Making Things Move DIY Mechanisms for Inventors, Hobbyists, and Artists written by Dustyn Roberts and published by McGraw Hill Professional. This book was released on 2010-12-06 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: Get Your Move On! In Making Things Move: DIY Mechanisms for Inventors, Hobbyists, and Artists, you'll learn how to successfully build moving mechanisms through non-technical explanations, examples, and do-it-yourself projects--from kinetic art installations to creative toys to energy-harvesting devices. Photographs, illustrations, screen shots, and images of 3D models are included for each project. This unique resource emphasizes using off-the-shelf components, readily available materials, and accessible fabrication techniques. Simple projects give you hands-on practice applying the skills covered in each chapter, and more complex projects at the end of the book incorporate topics from multiple chapters. Turn your imaginative ideas into reality with help from this practical, inventive guide. Discover how to: Find and select materials Fasten and join parts Measure force, friction, and torque Understand mechanical and electrical power, work, and energy Create and control motion Work with bearings, couplers, gears, screws, and springs Combine simple machines for work and fun Projects include: Rube Goldberg breakfast machine Mousetrap powered car DIY motor with magnet wire Motor direction and speed control Designing and fabricating spur gears Animated creations in paper An interactive rotating platform Small vertical axis wind turbine SADbot: the seasonally affected drawing robot Make Great Stuff! TAB, an imprint of McGraw-Hill Professional, is a leading publisher of DIY technology books for makers, hackers, and electronics hobbyists.

Mechanisms in Ancient Chinese Books with Illustrations

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3319020099
Total Pages : 310 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis Mechanisms in Ancient Chinese Books with Illustrations by : Kuo-Hung Hsiao

Download or read book Mechanisms in Ancient Chinese Books with Illustrations written by Kuo-Hung Hsiao and published by Springer Science & Business Media. This book was released on 2013-12-12 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a unique approach for studying mechanisms and machines with drawings that were depicted unclearly in ancient Chinese books. The historical, cultural and technical backgrounds of the mechanisms are explained, and various mechanisms described and illustrated in ancient books are introduced. By utilizing the idea for the conceptual design of modern mechanisms, all feasible designs of ancient mechanisms with uncertain members and joints that meet the technical standards of the subjects’ time periods are synthesized systematically. Ancient Chinese crossbows (the original crossbow and repeating crossbows), textile mechanisms (silk-reeling mechanism, spinning mechanisms, and looms), and many other artisan's tool mechanisms are used as illustrated examples. Such an approach provides a logical method for the reconstruction designs of ancient mechanisms with uncertain structures. It also provides an innovative direction for researchers to further identify the original structures of mechanisms and machines with drawings in ancient literature. This book can be used as a textbook and/or supplemental reading material for courses related to history of ancient (Chinese) machinery and creative mechanism design for senior and graduate students.

Molecular Mechanisms of Autonomy in Biological Systems

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Author :
Publisher : Springer
ISBN 13 : 3319918249
Total Pages : 142 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis Molecular Mechanisms of Autonomy in Biological Systems by : Tara Karimi

Download or read book Molecular Mechanisms of Autonomy in Biological Systems written by Tara Karimi and published by Springer. This book was released on 2018-07-28 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a novel molecular description for understanding the regulatory mechanisms behind the autonomy and self-organization in biological systems. Chapters focus on defining and explaining the regulatory molecular mechanisms behind different aspects of autonomy and self-organization in the sense of autonomous coding, data processing, structure (mass) formation and energy production in a biological system. Subsequent chapters discuss the cross-talk among mechanisms of energy, and mass and information, transformation in biological systems. Other chapters focus on applications regarding therapeutic approaches in regenerative medicine. Molecular Mechanisms of Autonomy in Biological Systems is an indispensable resource for scientists and researchers in regenerative medicine, stem cell biology, molecular biology, tissue engineering, developmental biology, biochemistry, biophysics, bioinformatics, as well as big data sciences, complexity and soft computing.

Classical and Modern Mechanisms for Engineers and Inventors

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Author :
Publisher : CRC Press
ISBN 13 : 9780824785277
Total Pages : 630 pages
Book Rating : 4.7/5 (852 download)

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Book Synopsis Classical and Modern Mechanisms for Engineers and Inventors by : Jensen

Download or read book Classical and Modern Mechanisms for Engineers and Inventors written by Jensen and published by CRC Press. This book was released on 1991-08-02 with total page 630 pages. Available in PDF, EPUB and Kindle. Book excerpt: Jensen (mechanical engineering, Mankato State U., Minn.) is a prolific designer/interpreter/reporter of mechanisms for the user of mechanical movements. This collection offers solutions or inspirations in some 20 areas including the slider crank, cycloid, screw and clamping mechanisms, antibacklash

Compliant Mechanisms

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Publisher : John Wiley & Sons
ISBN 13 : 9780471384786
Total Pages : 484 pages
Book Rating : 4.3/5 (847 download)

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Book Synopsis Compliant Mechanisms by : Larry L. Howell

Download or read book Compliant Mechanisms written by Larry L. Howell and published by John Wiley & Sons. This book was released on 2001-08-03 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Compliant Mechanisms" beschreibt eine besonders exakte, flexible und zuverlässige Entwurfsmethode im Maschinenbau, vorgestellt von einem international anerkannten Experten. Einem allgemeinen Überblick folgt die Erläuterung fortgeschrittener, moderner, zum Teil hochspezialisierter Anwendungen.

Mechanisms and Consciousness

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Author :
Publisher : Routledge
ISBN 13 : 1000480739
Total Pages : 232 pages
Book Rating : 4.0/5 (4 download)

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Book Synopsis Mechanisms and Consciousness by : Marek Pokropski

Download or read book Mechanisms and Consciousness written by Marek Pokropski and published by Routledge. This book was released on 2021-11-29 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book develops a new approach to naturalizing phenomenology. The author proposes to integrate phenomenology with the mechanistic framework that offers new methodological perspectives for studying complex mental phenomena such as consciousness. While mechanistic explanatory models are widely applied in cognitive science, their approach to describing subjective phenomena is limited. The author argues that phenomenology can fill this gap. He proposes two novel ways of integrating phenomenology and mechanism. First, he presents a new reading of phenomenological analyses as functional analyses. Such functional phenomenology delivers a functional sketch of a target system and provides constraints on the space of possible mechanisms. Second, he develops the neurophenomenological approach in the direction of dynamic modeling of experience. He shows that neurophenomenology can deliver dynamical constraints on mechanistic models and thus inform the search for an underlying mechanism. Mechanisms and Consciousness will be of interest to scholars and advanced students working in phenomenology, philosophy of mind, and the cognitive sciences.

A Brief Illustrated History of Machines and Mechanisms

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 904812512X
Total Pages : 228 pages
Book Rating : 4.0/5 (481 download)

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Book Synopsis A Brief Illustrated History of Machines and Mechanisms by : Emilio Bautista Paz

Download or read book A Brief Illustrated History of Machines and Mechanisms written by Emilio Bautista Paz and published by Springer Science & Business Media. This book was released on 2010-08-02 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Machines have always gone hand-in-hand with the cultural development of m- kind throughout time. A book on the history of machines is nothing more than a specific way of bringing light to human events as a whole in order to highlight some significant milestones in the progress of knowledge by a complementary persp- tive into a general historical overview. This book is the result of common efforts and interests by several scholars, teachers, and students on subjects that are connected with the theory of machines and mechanisms. In fact, in this book there is a certain teaching aim in addition to a general historical view that is more addressed to the achievements by “homo faber” than to those by “homo sapiens”, since the proposed history survey has been developed with an engineering approach. The brevity of the text added to the fact that the authors are probably not com- tent to tackle historical studies with the necessary rigor, means the content of the book is inevitably incomplete, but it nevertheless attempts to fulfil three basic aims: First, it is hoped that this book may provide a stimulus to promote interest in the study of technical history within a mechanical engineering context. Few are the co- tries where anything significant is done in this area, which means there is a general lack of knowledge of this common cultural heritage.

Mechanisms, Linkages and Mechanical Controls

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Author :
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (111 download)

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Book Synopsis Mechanisms, Linkages and Mechanical Controls by : Nicholas P. Chironis

Download or read book Mechanisms, Linkages and Mechanical Controls written by Nicholas P. Chironis and published by . This book was released on 1978 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Social Mechanisms

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Publisher : Cambridge University Press
ISBN 13 : 9780521596879
Total Pages : 356 pages
Book Rating : 4.5/5 (968 download)

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Book Synopsis Social Mechanisms by : Peter Hedström

Download or read book Social Mechanisms written by Peter Hedström and published by Cambridge University Press. This book was released on 1998-01-13 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: The advancement of social theory requires an analytical approach that systematically seeks to explicate the social mechanisms that generate and explain observed associations between events. These essays, written by prominent social scientists, advance criticisms of current trends in social theory and suggest alternative approaches. The mechanism approach calls attention to an intermediary level of analysis in between pure description and story-telling, on the one hand, and grand theorizing and universal social laws, on the other. For social theory to be of use for the working social scientist, it must attain a high level of precision and provide a toolbox from which middle range theories can be constructed.

Mechanisms of Gene Regulation

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Author :
Publisher : Springer
ISBN 13 : 9401777411
Total Pages : 219 pages
Book Rating : 4.4/5 (17 download)

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Book Synopsis Mechanisms of Gene Regulation by : Carsten Carlberg

Download or read book Mechanisms of Gene Regulation written by Carsten Carlberg and published by Springer. This book was released on 2016-06-06 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook aims to describe the fascinating area of eukaryotic gene regulation for graduate students in all areas of the biomedical sciences. Gene expression is essential in shaping the various phenotypes of cells and tissues and as such, regulation of gene expression is a fundamental aspect of nearly all processes in physiology, both in healthy and in diseased states. This pivotal role for the regulation of gene expression makes this textbook essential reading for students of all the biomedical sciences, in order to be better prepared for their specialized disciplines. A complete understanding of transcription factors and the processes that alter their activity is a major goal of modern life science research. The availability of the whole human genome sequence (and that of other eukaryotic genomes) and the consequent development of next-generation sequencing technologies have significantly changed nearly all areas of the biological sciences. For example, the genome-wide location of histone modifications and transcription factor binding sites, such as provided by the ENCODE consortium, has greatly improved our understanding of gene regulation. Therefore, the focus of this book is the description of the post-genome understanding of gene regulation. The purpose of this book is to provide, in a condensed form, an overview on the present understanding of the mechanisms of gene regulation. The authors are not aiming to compete with comprehensive treatises, but rather focus on the essentials. Therefore, the authors have favored a high figure-to-text ratio following the rule stating that “a picture tells more than thousand words”. The content of the book is based on the lecture course, which is given by Prof. Carlberg since 2001 at the University of Eastern Finland in Kuopio. The book is subdivided into 4 sections and 13 chapters. Following the Introduction there are three sections, which take a view on gene regulation from the perspective of transcription factors, chromatin and non-coding RNA, respectively. Besides its value as a textbook, Mechanisms of Gene Regulation will be a useful reference for individuals working in biomedical laboratories.

Fundamentals of Machine Theory and Mechanisms

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Author :
Publisher : Springer
ISBN 13 : 3319319701
Total Pages : 415 pages
Book Rating : 4.3/5 (193 download)

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Book Synopsis Fundamentals of Machine Theory and Mechanisms by : Antonio Simón Mata

Download or read book Fundamentals of Machine Theory and Mechanisms written by Antonio Simón Mata and published by Springer. This book was released on 2016-05-27 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book develops the basic content for an introductory course in Mechanism and Machine Theory. The text is clear and simple, supported by more than 350 figures. More than 60 solved exercises have been included to mark the translation of this book from Spanish into English. Topics treated include: dynamic analysis of machines; introduction to vibratory behavior; rotor and piston balanced; critical speed for shafts; gears and train gears; synthesis for planar mechanisms; and kinematic and dynamic analysis for robots. The chapters in relation to kinematics and dynamics for planar mechanisms can be studied with the help of WinMecc software, which allows the reader to study in an easy and intuitive way, but exhaustive at the same time. This computer program analyzes planar mechanisms of one-degree of freedom and whatever number of links. The program allows users to build a complex mechanism. They can modify any input data in real time changing values in a numeric way or using the computer mouse to manipulate links and vectors while mechanism is moving and showing the results. This powerful tool does not only show the results in a numeric way by means of tables and diagrams but also in a visual way with scalable vectors and curves.

Translation Mechanisms and Control

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Author :
Publisher :
ISBN 13 : 9781621821861
Total Pages : 499 pages
Book Rating : 4.8/5 (218 download)

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Book Synopsis Translation Mechanisms and Control by : Michael B. Mathews

Download or read book Translation Mechanisms and Control written by Michael B. Mathews and published by . This book was released on 2018-09-30 with total page 499 pages. Available in PDF, EPUB and Kindle. Book excerpt: A subject collection from Cold Spring Harbor Perspectives in Biology.

Mechanisms in Bioenergetics

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (879 download)

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Book Synopsis Mechanisms in Bioenergetics by : Efraim Racker

Download or read book Mechanisms in Bioenergetics written by Efraim Racker and published by . This book was released on 1967 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: