Immunology of Ocular Tumors

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Author :
Publisher : CRC Press
ISBN 13 : 9789026519314
Total Pages : 284 pages
Book Rating : 4.5/5 (193 download)

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Book Synopsis Immunology of Ocular Tumors by : M. Jager

Download or read book Immunology of Ocular Tumors written by M. Jager and published by CRC Press. This book was released on 2002-01-01 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: The eye and the ocular adnexa may give rise to over three hundred histologically different tumors - by far the largest tumor variety of the human body. However, the immunological behavior of these tumors has only been explored in some cases, although it is well established that the eye is an immune-privileged site in which cells that express foreign antigens escape immune-mediated elimination. Human tumors also create an immune-privileged surrounding and thereby escape from anti-tumor immune responses. Highlighting aspects of ocular and general tumor, this text summarizes the role of the immune system and how tumor tissue can influence various parameters (T-cells, NK-cells, HLA-expression, apoptosis), leading to escape mechanisms used by the tumor. New therapeutic regimens urgently required by patients are also reviewed, and the immunological behavior of skin melanoma is compared to choroidal melanoma, whilst basal cell carcinoma of the ocular lid is compared to those of the skin.

Immunology, Inflammation and Diseases of the Eye

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Author :
Publisher : Academic Press
ISBN 13 : 0123819741
Total Pages : 452 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Immunology, Inflammation and Diseases of the Eye by : Darlene A. Dartt

Download or read book Immunology, Inflammation and Diseases of the Eye written by Darlene A. Dartt and published by Academic Press. This book was released on 2011-05-05 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: This selection of articles from the Encyclopedia of the Eye provides a comprehensive overview of immunological features, diseases and inflammation of the eye and its support structures and organs. Rather than taking an immunological focus that is strictly suitable for clinicians, the volume offers a considerable basic science background and addresses a broad range of topics - the immune system of the eye, its various disorders, mechanisms of inflammation of the eye and visual system, treatment, wound healing mechanisms, stem cells, and more. The first single volume to integrate comparative studies into a comprehensive resource on the neuroscience of ocular immunology Chapters are carefully selected from the Encyclopedia of the Eye by the world's leading vision researchers The best researchers in the field provide their conclusions in the context of the latest experimental results

Immune Response and the Eye

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Author :
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805568932
Total Pages : 239 pages
Book Rating : 4.8/5 (55 download)

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Book Synopsis Immune Response and the Eye by : J. Wayne Streilein

Download or read book Immune Response and the Eye written by J. Wayne Streilein and published by Karger Medical and Scientific Publishers. This book was released on 1999-01-01 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, the physiologic bases of ocular immune privilege and the distinctive systemic immune responses elicited by eye derived antigens are described. Several chapters discuss the pathogeneses of these disorders which arise from infections, autoimmunity, and neoplasms. Finally, chapters devoted to corneal and retinal transplantation describe attempts to exploit ocular immune privilege to promote graft survival and thereby cure blindness. Ophthalmologists, both clinicians and physician scientists, general and tumor immunologists, transplantation biologists and anyone seeking to understand the immunopathogenic diseases that threaten vision will appreciate the information presented in this book.

Ocular Immunology in Health and Disease

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Author :
Publisher :
ISBN 13 :
Total Pages : 212 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Ocular Immunology in Health and Disease by : Steven B. Koevary

Download or read book Ocular Immunology in Health and Disease written by Steven B. Koevary and published by . This book was released on 1999 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides detailed information about ocular immunity and the basis of ocular immune privilege, and elaborates on the role of immune effector mechanisms in specific ocular conditions. Offers a detailed overview of immune system function, discusses autoimmune diseases and allergic conditions affecting the eye and their treatment, reviews the immunology of corneal graft rejection, and discusses the immune system's role in ocular tumor elimination and corneal transplant. Annotation copyrighted by Book News, Inc., Portland, OR

Immunology of Uveitis and Ocular Tumors

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Author :
Publisher : Harcourt Health Sciences Group
ISBN 13 :
Total Pages : 152 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Immunology of Uveitis and Ocular Tumors by : Devron H. Char

Download or read book Immunology of Uveitis and Ocular Tumors written by Devron H. Char and published by Harcourt Health Sciences Group. This book was released on 1978 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Ocular Immunology

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Author :
Publisher : Little, Brown Medical Division
ISBN 13 :
Total Pages : 384 pages
Book Rating : 4.:/5 (44 download)

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Book Synopsis Ocular Immunology by : Gilbert Smolin

Download or read book Ocular Immunology written by Gilbert Smolin and published by Little, Brown Medical Division. This book was released on 1986 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Current Concepts in Uveal Melanoma

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Author :
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805597916
Total Pages : 196 pages
Book Rating : 4.8/5 (55 download)

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Book Synopsis Current Concepts in Uveal Melanoma by : L. Desjardins

Download or read book Current Concepts in Uveal Melanoma written by L. Desjardins and published by Karger Medical and Scientific Publishers. This book was released on 2011-10-24 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: Uveal melanoma is an aggressive form of cancer that can involve the iris, the ciliary body, and/or the choroid, which is the main location of this tumor. Patients often wish to be informed about treatment choices and the results of different approaches. Important current clinical questions are whether a biopsy should be taken of choroidal melanomas, what should be done with this biopsy, and whether high-risk patients should be screened regularly.This volume describes the clinical characteristics of uveal melanoma along with the different current techniques available for treatment, such as radioactive plaque treatment, proton beam therapy, and local tumor resection. Furthermore, techniques for taking biopsies and characterizing biopsy material are demonstrated. Future therapies such as anti-VEGF treatment and options for the treatment of metastases are also discussed. Residents with an interest in ocular oncology, ophthalmologists or physicians dealing with uveal melanoma, as well as patients wishing to know more about this malignancy will find a topical update on uveal melanoma in this publication.

Clinical Ophthalmic Oncology

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Publisher : Springer
ISBN 13 : 3030044890
Total Pages : 328 pages
Book Rating : 4.0/5 (3 download)

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Book Synopsis Clinical Ophthalmic Oncology by : Arun D. Singh

Download or read book Clinical Ophthalmic Oncology written by Arun D. Singh and published by Springer. This book was released on 2019-03-12 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by internationally renowned experts, the 3rd edition of this six volume textbook provides detailed practical guidance and advice on the diagnosis and management of the complete range of ocular cancers. Supplying the reader with state-of-the-art knowledge required in order to identify these cancers early and to treat them as effectively as possible, this book is divided into six volumes: Basic Principles, Eyelid and Conjunctival Tumors, Orbital Tumors, Uveal Tumors, Retinal Tumors, and Retinoblastoma. The information presented enables readers to provide effective patient care using the latest knowledge on ophthalmic oncology and to verify diagnostic conclusions based on comparison with numerous full-color clinical photographs from the authors' private collections, histopathologic microphotographs, imaging studies, and crisp illustrations. Clinical Ophthalmic Oncology's clinically focused and user-friendly format allows for rapid retrieval of information in daily practice and is written for residents, fellows, and any physician involved in the care of patients with ocular or orbital malignancies. Additionally, this six volume edition adds several hundred new images to improve comprehension of procedures and techniques. This volume provides essential information on cancer epidemiology, etiology, pathology, angiogenesis, immunology, genetics, and staging systems and explains the principles underlying different therapeutic approaches.​

Clinical Ophthalmic Oncology

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642404898
Total Pages : 239 pages
Book Rating : 4.6/5 (424 download)

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Book Synopsis Clinical Ophthalmic Oncology by : Arun D. Singh

Download or read book Clinical Ophthalmic Oncology written by Arun D. Singh and published by Springer Science & Business Media. This book was released on 2013-11-26 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by internationally renowned experts, Clinical Ophthalmic Oncology provides practical guidance and advice on the diagnosis and management of the complete range of ocular cancers. The book supplies all of the state-of-the-art knowledge required in order to identify these cancers early and to treat them as effectively as possible. Using the information provided, readers will be able to provide effective patient care using the latest knowledge on all aspects of ophthalmic oncology, to verify diagnostic conclusions based on comparison with numerous full-color clinical photographs, and to locate required information quickly owing to the clinically focused and user-friendly format. This volume provides essential information on cancer epidemiology, etiology, pathology, angiogenesis, immunology, genetics, and staging systems and explains the principles underlying different therapeutic approaches.​

Immuno-ophthalmology

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Author :
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805568630
Total Pages : 260 pages
Book Rating : 4.8/5 (55 download)

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Book Synopsis Immuno-ophthalmology by : Uwe Pleyer

Download or read book Immuno-ophthalmology written by Uwe Pleyer and published by Karger Medical and Scientific Publishers. This book was released on 1999-01-01 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although considerable light has been shed on the mechanisms of ocular immunity over the past 20 years, a complete understanding still eludes our grasp. To many ophthalmologists immunology itself is a comparatively new field. This volume will bring the latest findings in immunological research and the resulting new therapy methods to the ophthalmologist in practice. The scope of the topics goes from general principles of immuno-ophthalmology to more specific ones such as immunology of corneal transplantation or immune regulation of uveoretinal inflammation. With its broad scope of contributions, this publication will not only be significant to the ophthalmologist, but also to pediatricians, specialists in internal medicine as well as dermatologists confronted with eye diseases.

Immunology of Eye Diseases

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 9400924909
Total Pages : 178 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis Immunology of Eye Diseases by : S. Lightman

Download or read book Immunology of Eye Diseases written by S. Lightman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: The eye can become involved in immune-mediated diseases that affect it alone or as part of a multi-organ disease process. Much immunological attention has been focused on other organs affected by these processes and the subject of the immunology of eye diseases is a relatively new one. Many of these diseases that involve the eye are not life-threatening but can result in devastat ing loss of sight that if bilateral, will have major effects on the patient's life. Systemic immunological investigations are generally unhelpful in these patients and one of the major problems in this field has been the lack of diseased tissue available for examination to determine the pathological processes involved. Our poor understanding of basic mechanisms of disease in the eye has meant that treatment of many of these conditions is often inadequate. It has become possible to apply in the eye many ofthe techniques used to investigate the role of the immune system in other systems. Animal models of many of the disease processes have also allowed dissection of the immune response both within and outside the eye. It is my belief that a greater understanding of the mechanisms by which the structures in the eye become damaged will allow more specific and effective therapeutic strategies to be devised.

Advances in Tumor Immunology and Immunotherapy

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Publisher : Springer Science & Business Media
ISBN 13 : 1461488095
Total Pages : 369 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Advances in Tumor Immunology and Immunotherapy by : Joseph D. Rosenblatt

Download or read book Advances in Tumor Immunology and Immunotherapy written by Joseph D. Rosenblatt and published by Springer Science & Business Media. This book was released on 2013-10-25 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in understanding of fundamental immunology have created new insights into the dynamic interactions between tumors and the immune system. This includes new understanding of T- and B-cell interaction, immune inhibitory mechanisms including the biology of T regulatory cells, myeloid suppressor cells, and dendritic cell subsets. Enhanced understanding of mechanisms underlying T-cell anergy such as arginine deprivation, immunosuppressive cytokines, defective innate and interferon response pathways, and NKG2D downregulation have all provided new insight into suppression of anti-tumor immunity and tumor evasion. In addition to emerging understanding of tumor evasion, new immune targets such as CTLA4 blockade, NK stimulatory receptors, manipulation of the antigen processing and presentation, cytokine and costimulatory responses all provide new possibilities for enhancing anti-tumor immunity even in tumors previously felt to be resistant to immune attack. Several of these strategies have already been realized in the clinic. The volume will explore evolving paradigms in antigen presentation, dendritic cell biology, the innate response and immunosuppressive mechanisms, and emerging strategies for manipulation of the immune system for therapeutic benefit that have realized success in neuroblastoma, leukemia, melanoma, lung cancer, and allogeneic transplantation. Early successes as well as failures will be highlighted to provide a snapshot of the state of clinical immunotherapy with an eye to future possibilities such as combination therapies, adoptive T-cell transfer, and the retargeting of immune cells via T-cell receptor engineering.

Innate Immunity and the Eye

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Author :
Publisher : JP Medical Ltd
ISBN 13 : 9350903091
Total Pages : 246 pages
Book Rating : 4.3/5 (59 download)

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Book Synopsis Innate Immunity and the Eye by : Manfred Zierhut

Download or read book Innate Immunity and the Eye written by Manfred Zierhut and published by JP Medical Ltd. This book was released on 2013-04-30 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: The innate immune system comprises the cells and mechanisms that are the first line of defence against infection by other organisms. This book provides a comprehensive synopsis of eye diseases, their immunological mechanisms and the role of the immune cells and mediators. Beginning with an introduction to the role of the innate immune system, the following chapters discuss the different types of immune cells in the eye and their role in the etiopathogenesis of various diseases including glaucoma and age-related macular degeneration. Edited by Manfred Zierhut, recognised expert from the University of Tuebingen Germany, this book is presented in an easy to read format, enabling practitioners to understand even the most sophisticated eye disorders from an immunological perspective. Key points Comprehensive synopsis of the role of the innate immune system in eye diseases Covers different types of immune cells Edited by internationally recognised specialist in Germany

Immune Response and the Eye

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Author :
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805581874
Total Pages : 357 pages
Book Rating : 4.8/5 (55 download)

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Book Synopsis Immune Response and the Eye by : Jerry Y. Niederkorn

Download or read book Immune Response and the Eye written by Jerry Y. Niederkorn and published by Karger Medical and Scientific Publishers. This book was released on 2007-01-01 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: In memory of J. Wayne Streilein, the pioneer in ocular immunology The second edition of Immune Response and the Eye' highlights recent insights into the dangerous compromise' between the immune system and the eye, which protects the eye against pathogens while limiting inflammation and immune-mediated injury to ocular tissues with little or no regenerative potential. It discusses the broad spectrum of physiological, immunological, anatomical, and biochemical adaptations that conspire to closely regulate the tone and tenor of immune responses in the eye. This volume further describes immune-mediated diseases that occur when the compromise between the immune system and the eye is breached. This breakdown in immune privilege threatens the vision of millions each year. Finally, recent advances in ocular immunology are presented, which offer potential therapeutic applications in corneal and retinal transplantation and in the management of blinding autoimmune diseases of the eye. Eye researchers, ophthalmologists and immunologists will appreciate the state-of-the-art and authoritative information presented in Immune Response and the Eye'

Immunology and Immunopathology of the Eye

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Author :
Publisher :
ISBN 13 :
Total Pages : 408 pages
Book Rating : 4.:/5 (44 download)

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Book Synopsis Immunology and Immunopathology of the Eye by : Arthur M. Silverstein

Download or read book Immunology and Immunopathology of the Eye written by Arthur M. Silverstein and published by . This book was released on 1979 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Eye and Immunology

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Author :
Publisher :
ISBN 13 :
Total Pages : 240 pages
Book Rating : 4.:/5 (44 download)

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Book Synopsis The Eye and Immunology by : Mathea R. Allansmith

Download or read book The Eye and Immunology written by Mathea R. Allansmith and published by . This book was released on 1982 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Tumor Immunology

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Author :
Publisher : CRC Press
ISBN 13 : 0203301854
Total Pages : 224 pages
Book Rating : 4.2/5 (33 download)

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Book Synopsis Tumor Immunology by : Giorgio Parmiani

Download or read book Tumor Immunology written by Giorgio Parmiani and published by CRC Press. This book was released on 2002-04-25 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in immunology and molecular biology have resulted in new therapeutic approaches being generated and implemented in cancer clinics. The discovery of new antigens, mechanisms of antigen presentation, and interplay of cells involved in anti-tumor immunity have made the clinical control of some cancers more plausible than previously tho