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Immunology In Diabetes
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Book Synopsis Pathophysiology and Complications of Diabetes Mellitus by : Oluwafemi Oguntibeju
Download or read book Pathophysiology and Complications of Diabetes Mellitus written by Oluwafemi Oguntibeju and published by BoD – Books on Demand. This book was released on 2012-11-14 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes mellitus is a complex, progressive disease, which is accompanied by multiple complications. It is a metabolic disorder of the endocrine system and listed among the most common disorders in both developed and developing countries. It has a global metabolic epidemic and it is estimated that the number of people affected by the disease will rise from the current 150 to 230 million by 2025. Hyperglycaemia is a characteristic feature of diabetes mellitus and chronic hyperglycaemia could lead to long-term complications in the eyes, kidneys, nerves, heart and blood vessels. Interestingly, this book examines the pathophysiology and selected complications in diabetes mellitus.
Book Synopsis Immunology of Diabetes by : William James Irvine
Download or read book Immunology of Diabetes written by William James Irvine and published by . This book was released on 1980 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Immunotherapy of Type 1 Diabetes by : Domenico Andreani
Download or read book Immunotherapy of Type 1 Diabetes written by Domenico Andreani and published by John Wiley & Sons. This book was released on 1989 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent national, European and international diabetes meetings have seen controversial discussions on the potential benefit and also on ethical aspects of immune intervention in patients with Type 1 diabetes or in persons with a high risk of developing the disease.
Book Synopsis Frontiers in Clinical Drug Research - Diabetes and Obesity by : Atta-ur-Rahman
Download or read book Frontiers in Clinical Drug Research - Diabetes and Obesity written by Atta-ur-Rahman and published by Bentham Science Publishers. This book was released on 2016-06-07 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: Frontiers in Clinical Drug Research – Diabetes and Obesity is an eBook series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of two metabolic diseases – diabetes and obesity. The scope of the eBook series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs affecting endocrine and metabolic processes linked with diabetes and obesity. Reviews in this series also include research on specific receptor targets and pre-clinical / clinical findings on novel pharmaceutical agents. Frontiers in Clinical Drug Research – Diabetes and Obesity is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of diabetes and obesity research. The second volume of this series features 7 reviews presenting updates on hormones and several classes of drugs: -Osteocalcin action in glucose metabolism -Sodium-glucose co-transporter 2 (SGLT2) inhibitors -Glucagon-like peptide-1 (GLP-1) mimetics -Dipeptidyl peptidase 4 (DPP-4) inhibitors -New drugs in clinical trial and commercial phases
Book Synopsis Type I Diabetes by : George S. Eisenbarth
Download or read book Type I Diabetes written by George S. Eisenbarth and published by . This book was released on 1996 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Type I diabetes is rapidly becoming one of the most studied autoimmune disorders. The existence of two spontaneous animal models, transgenic models which both create or suppress disease, coupled with the clinical importance of the illness with millions affected and thousands killed each year, has led to enormous efforts by an international groups of investigators to understand, treat and prevent type I diabetes. This timely new book presents a synthesis of the molecular and cellular immunology of type I diabetes by basic immunologists and physician investigators at the Barbara Davis Center for Childhood Diabetes. At this center, T cell clones able to produce diabetes were discovered, the first antigen with which they react characterized, combinatorial, biochemical autoantibody screening for diabetes risk was recently published and multiple trials for the prevention of type I diabetes were carried out. This volume discusses the latest research in this rapidly developing field, including diagnostic strategies and therapies being developed to prevent this disease.
Download or read book Endocrine Immunology written by W. Savino and published by Karger Medical and Scientific Publishers. This book was released on 2017-02-28 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last decades, several in vitro and in vivo studies have revealed the existence of a very complex network between the neuroendocrine and immune system. Important molecular mechanisms underlying these interactions, in both physiological and pathological conditions, have also been described. Indeed, hormones play a pivotal role in the development and functional regulation of the immune system – both innate and acquired responses. Immune system cells present specific hormone receptors and themselves produce some hormones, thus influencing hormone secretion. More recently, the modulation of hormone secretion has been attempted for treating associated autoimmune disorders, further supporting the strong interplay between the endocrine and immune system. Distinguished experts, who have published extensively in their fields, have contributed comprehensive chapters to this volume. The focus is on the various aspects of endocrine-neuro-immune connections, providing an updated panorama - from basics to clinical applications - of current knowledge and still debated issues.
Book Synopsis The Beautiful Cure by : Daniel M. Davis
Download or read book The Beautiful Cure written by Daniel M. Davis and published by University of Chicago Press. This book was released on 2021-03-19 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: “A terrific book by a consummate storyteller and scientific expert considers the past and future of the body’s ability to fight disease and heal itself.” —Adam Rutherford, The Guardian The immune system holds the key to human health. In The Beautiful Cure, leading immunologist Daniel M. Davis describes how the scientific quest to understand how the immune system works—and how it is affected by stress, sleep, age, and our state of mind—is now unlocking a revolutionary new approach to medicine and well-being. The body’s ability to fight disease and heal itself is one of the great mysteries and marvels of nature. But in recent years, painstaking research has resulted in major advances in our grasp of this breathtakingly beautiful inner world: a vast and intricate network of specialist cells, regulatory proteins, and dedicated genes that are continually protecting our bodies. Far more powerful than any medicine ever invented, the immune system plays a crucial role in our daily lives. We have found ways to harness these natural defenses to create breakthrough drugs and so-called immunotherapies that help us fight cancer, diabetes, arthritis, and many age-related diseases, and we are starting to understand whether activities such as mindfulness might play a role in enhancing our physical resilience. Written by a researcher at the forefront of this adventure, The Beautiful Cure tells a dramatic story of scientific detective work and discovery, of puzzles solved and mysteries that linger, of lives sacrificed and saved. With expertise and eloquence, Davis introduces us to this revelatory new understanding of the human body and what it takes to be healthy. “Visceral.” —The Wall Street Journal “Illuminating.” —Publishers Weekly “Heroic.” —Science
Book Synopsis Janeway's Immunobiology by : Kenneth Murphy
Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Book Synopsis Targeting a Cure for Type 1 Diabetes: How Long Will We Have to Wait? by : Lisa S. Rotenstein
Download or read book Targeting a Cure for Type 1 Diabetes: How Long Will We Have to Wait? written by Lisa S. Rotenstein and published by American Diabetes Association. This book was released on 2013-04-17 with total page 147 pages. Available in PDF, EPUB and Kindle. Book excerpt: Will type 1 diabetes ever be cured? Everyone whose lives are touched by type 1 diabetes hopes for a cure but hard facts are difficult to find. Targeting a Cure for Type 1 Diabetes chronicles the diverse efforts now underway to answer this critical question. The writers from diaTribe (www.diaTribe.org), an award-winning free online newsletter about diabetes, have collaborated with the American Diabetes Association to explain the research and to lay out their objective assessment of each therapy—giving readers a clear understanding of the potential each treatment holds and the optimism each deserves. Highlighting the opportunities and obstacles, this book focuses on the four most promising research areas: immune therapeutics, islet and pancreas transplantation, beta-cell regeneration and survival agents, and the artificial pancreas. As a person who has lived with type 1 diabetes for 26 years and an expert on the business of diabetes therapies, diaTribe editor-in-chief Kelly Close understands the weight of this all-important question and provides her personal commentary on where we stand in the search for a cure. The book features a foreword by Dr. Robert Ratner, Chief Scientific and Medical Officer for the American Diabetes Association, and an introduction from Dr. Aaron Kowalski, Vice President, Treatment Therapies, for JDRF. As they remind us, the search for the cure is ultimately about patients, and this book is written to give you true hope—one that is strengthened by data and facts. After reading about Kelly Close and her teams’ incredible journey of discovery, we cannot only continue to dream, but we can open our eyes each morning to a reality that brings us closer, inch by inch, discovery by discovery, to a day when glucose control will be automatic and people with type 1 diabetes will be “cured.” —Dr. Francine Kaufman, Chief Medical Officer and Vice President, Medtronic Diabetes
Book Synopsis Understanding the Host Immune Response Against Mycobacterium tuberculosis Infection by : Vishwanath Venketaraman
Download or read book Understanding the Host Immune Response Against Mycobacterium tuberculosis Infection written by Vishwanath Venketaraman and published by Springer. This book was released on 2018-09-26 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: According to the World Health Organization, approximately one third of the world’s population is latently infected with Mycobacterium tuberculosis (M. tb [LTBI]), of whom about 9 million have active tuberculosis (TB). It is estimated that approximately 2 million individuals die each year from active TB. An estimated 14.4% of these individuals have HIV and M. tb co-infection. TB has long been known to be one of the leading causes of death in HIV-infected individuals. Recent evidence now indicates that individuals with type 2 diabetes, the elderly, and chronic smokers are also increasingly susceptible to TB infection, the ability of their immune system to fight off active TB infection having been compromised by their condition. This book therefore aims to provide a detailed review of recent advances in the research that involves characterizing the host’s immune responses against TB infection in conditions such as HIV, diabetes, chronic cigarette smoking and aging, and strategies to restore favorable immune responses against this deadly pathogen.
Book Synopsis Stem Cells – From Hype to Real Hope by : Khawaja Husnain Haider
Download or read book Stem Cells – From Hype to Real Hope written by Khawaja Husnain Haider and published by Walter de Gruyter GmbH & Co KG. This book was released on 2018-12-17 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a compilation of the bench experience of leading experts from various research labs involved in the cutting edge area of research. The authors describe the use of stem cells both as part of the combinatorial therapeutic intervention approach and as tools (disease model) during drug development, highlighting the shift from a conventional symptomatic treatment strategy to addressing the root cause of the disease process. The book is a continuum of the previously published book entitled "Stem Cells: from Drug to Drug Discovery" which was published in 2017.
Book Synopsis Idiotypes in Medicine: Autoimmunity, Infection and Cancer by : R.C. Kennedy
Download or read book Idiotypes in Medicine: Autoimmunity, Infection and Cancer written by R.C. Kennedy and published by Elsevier. This book was released on 1997-11-19 with total page 557 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the most comprehensive review of the idiotypic network available. All the current knowledge of idiotypes of the various antibodies is incorporated in this volume. The pathogenic role of idiotypes in autoimmunity and cancer is reviewed in depth. The therapeutic part focusses on harnessing anti-idiotypes for treating autoimmunological disorders, and on the employment of idiotypes for vaccines in cancer and infectious diseases, as well as explaining the manipulation of the idiotypic network in autoimmunity and cancer idiotypes and vaccines.
Book Synopsis Diabetes Mellitus by : Derek LeRoith
Download or read book Diabetes Mellitus written by Derek LeRoith and published by Lippincott Williams & Wilkins. This book was released on 2004 with total page 1608 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thoroughly revised and updated, this Third Edition encompasses the most recent advances in molecular and cellular research and describes the newest therapeutic modalities for type 1 and type 2 diabetes mellitus. Chapters by leading experts integrate the latest basic science and clinical research on diabetes mellitus and its complications. The text is divided into ten major sections, including extensive sections on therapeutics, diabetes during pregnancy, and complications. New chapters cover stem cell therapy for type 1 diabetes; genetics and treatment of obesity; new therapies to promote insulin action; vasculopathy; islet cell protocols; triglycerides in muscle; hypoglycemia in the adult; and the Diabetes Prevention Program.
Book Synopsis Current Topics in Diabetes Research by : Francesco Belfiore
Download or read book Current Topics in Diabetes Research written by Francesco Belfiore and published by . This book was released on 1993 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Features up-to-date reviews of the most advanced clinical methods currently being used to evaluate the metabolic and biological alterations accompanying diabetic disease. Additionally, the volume analyzes the complex plurimetabolic syndrome, commonly known as syndrome X.
Book Synopsis Collaborative Framework for Care and Control of Tuberculosis and Diabetes by : World Health Organization
Download or read book Collaborative Framework for Care and Control of Tuberculosis and Diabetes written by World Health Organization and published by . This book was released on 2011 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Given the absence of international guidelines on the joint management and control of TB and diabetes, the World Health Organization (WHO) and the International Union Against Tuberculosis and Lung Disease (the Union) identified key questions to be answered and commissioned systematic reviews of studies addressing those questions. A series of expert consultations were organized to assess the findings of the systematic reviews and a guideline group was established to develop this provisional collaborative framework. The framework aims to guide national programmes, clinicians and others engaged in care of patients and prevention and control of diabetes and TB on how to establish a coordinated response to both diseases, at organizational and clinical levels. The framework is based on evidence collated from systematic reviews and existing guidelines on the diagnosis and management of TB and diabetes. The systematic reviews confirmed the weak evidence base for the effectiveness and cost-effectiveness of collaborative interventions. The framework is therefore provisional; several of its recommendations are provisional pending better evidence. In order to provide advice on how to fill the knowledge gaps, the framework includes a list of priority research areas."--Page vii-viii.
Book Synopsis HLA and MHC by : Michael J. Browning
Download or read book HLA and MHC written by Michael J. Browning and published by Taylor & Francis. This book was released on 1996 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a review of the major histocompatibility complex (MHC), and the role it plays in the immune response and in disease. The emphasis throughout is on the human MHC, but relevant animal studies are inclded to give a comprehensive review of the subject.
Download or read book Diabetes written by Carla J Greenbaum and published by CRC Press. This book was released on 2019-08-30 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes has garnered worldwide attention and research funding as clinicians and researchers seek to better understand its pathogenesis, prevention, complications management, and impact and relationship to other diseases (heart disease, kidney disease, infections, and inflammation). Clinicians are overwhelmed with rapidly evolving developments regarding the science and clinical management of diabetes and are struggling to understand and apply new diabetes information. Diabetes: Translating Research into Practice will provide a concise interpretation of translational diabetes research for the purpose of preparing clinicians to understand and effectively deploy new strategies and therapeutics into the clinical care of diabetes patients by examining: the contrast between existing information in the clinical practice versus the basis and need for future clinical trials breakthroughs within clinical trials and methods to incorporate bench to bedside material for the clinical practice the synthesis and interpretation of the scientific principles, trial results, and clinical implications of emerging and translational therapies, and the management strategies for diabetic patients the entire scope of translational diabetes research from biology to screening and prognosis, new therapeutics, insulin, transplantation, and complications management new therapeutic strategies to knowledgeably and effectively equip the practicing clinician assembles information that is scattered throughout the diabetic community into one concise single reference
