Immunobiology of the Complement System

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Publisher :
ISBN 13 :
Total Pages : 296 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Immunobiology of the Complement System by : Gordon D. Ross

Download or read book Immunobiology of the Complement System written by Gordon D. Ross and published by . This book was released on 1986 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunobiology of the Complement System: An Introduction for Research and Clinical Medicine provides an introduction to the complement system. The intention was to create a primer that would provide the basic knowledge of complement required for either research or clinical medicine in diseases involving the complement system. The book begins with a historical background of complement research; it introduces certain key investigators from the past who have made important contributions. Separate chapters on the basic aspects of complement function are followed by chapters on the molecular genet ...

Innate Immunity of Plants, Animals and Humans

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Publisher : Springer Science & Business Media
ISBN 13 : 3540739300
Total Pages : 248 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Innate Immunity of Plants, Animals and Humans by : Holger Heine

Download or read book Innate Immunity of Plants, Animals and Humans written by Holger Heine and published by Springer Science & Business Media. This book was released on 2007-12-07 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book has been cunningly designed to provide an overview of our current knowledge about the innate immune systems of these three types of organisms. It not only covers the innate immune mechanisms and responses of such diverse organisms as plants, Cnidaria, Drosophila, urochordates and zebrafish, but also the major receptor systems in mammalians and humans. It delves too into the central defense mechanisms, antimicrobial peptides and the complement system.

Janeway's Immunobiology

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Publisher : Garland Science
ISBN 13 : 9780815344575
Total Pages : pages
Book Rating : 4.3/5 (445 download)

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Book Synopsis Janeway's Immunobiology by : Kenneth Murphy

Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Immunobiology of the Complement System

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Publisher : Academic Press
ISBN 13 : 1483276392
Total Pages : 286 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Immunobiology of the Complement System by : Gordon D. Ross

Download or read book Immunobiology of the Complement System written by Gordon D. Ross and published by Academic Press. This book was released on 2014-06-28 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunobiology of the Complement System: An Introduction for Research and Clinical Medicine provides an introduction to the complement system. The intention was to create a primer that would provide the basic knowledge of complement required for either research or clinical medicine in diseases involving the complement system. The book begins with a historical background of complement research; it introduces certain key investigators from the past who have made important contributions. Separate chapters on the basic aspects of complement function are followed by chapters on the molecular genetics of complement and the role of complement in different diseases. Key topics discussed include the activation of complement via the classical pathway and the alternative pathway; complement mediators of inflammation; opsonization and membrane complement receptors; assembly and functions of the terminal components; and complement-dependent mechanisms of virus neutralization. This book has been written primarily for students and scientists who have not been specifically trained in complement research.

The Complement System

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Publisher : Springer Science & Business Media
ISBN 13 : 3642970389
Total Pages : 549 pages
Book Rating : 4.6/5 (429 download)

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Book Synopsis The Complement System by : Klaus Rother

Download or read book The Complement System written by Klaus Rother and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 549 pages. Available in PDF, EPUB and Kindle. Book excerpt: Upon contemplating an updated version of the 1974 edition of this book and envisioning its possible organization, it immediately became evident that the new version could no longer be written by one, two, or even three authors. The field has experienced an explosive expansion in various directions, and the wealth of newer data which has been accumulated over the last decade can hardly be presented by a single author in a critical and coherent manner. On the other hand, it appears worthwhile not to abandon the attempt to come foreward with a review which describes as comprehensively as possible the progress and the state of knowledge. It is the aim of this volume to present a general and comprehensive review on complement. It is intended not only for individuals working in this area, but also for those who are less familiar with the field. Several chapters in the book describe state-of-the-art experimental methods which are helpful to critically evaluate the experimental data. Simultaneously, they may provide the necessary technical tools for those who wish to enter this highly provocative and exciting field.

Immunobiology of the Complement System

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Publisher : American Medical Publishers
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.8/5 (874 download)

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Book Synopsis Immunobiology of the Complement System by : Adah Blair

Download or read book Immunobiology of the Complement System written by Adah Blair and published by American Medical Publishers. This book was released on 2023-09-19 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The complement system is a part of the immune system which improves the capability of phagocytic cells and antibodies to take out damaged cells and microbes from the organism's body. Complement control proteins, which are found in a higher concentration in the blood plasma as compared to complement proteins, regulate the complement system. Some of the complement control proteins are found on the membranes of self-cells that protect them from attack by the complement system. This system is considered to be focused on killing bacteria that infect the host organism. Furthermore, it acts as an innate immune surveillance system, which has a significant role to play in host homeostasis, defense against pathogens and inflammation. The dysfunction of the complement system is a major reason of diseases caused in the central nervous system, such as neurodegenerative conditions like spinal cord injuries and Alzheimer's disease. C3 glomerulopathy and atypical hemolytic uremic syndrome have been found linked with mutations in the genes of complement regulators specifically factor H. The readers would gain knowledge that would broaden their perspective about the complement system and its immunobiology through this book. It will help the readers in keeping pace with the rapid changes in this area of study.

Molecular Biology of the Cell

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Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of the Cell by :

Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Complement System

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Publisher : Springer Science & Business Media
ISBN 13 : 1402080565
Total Pages : 566 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis The Complement System by : Janos Szebeni

Download or read book The Complement System written by Janos Szebeni and published by Springer Science & Business Media. This book was released on 2007-05-08 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt: As a phylogenetically old system complement is now regarded as a part of innate immunity. But it is much more than that. It bridges innate and adapted immunity, participates not only in host defense but also in many essential physiological processes, old and new diseases and adverse conditions. Indeed, complement became a term that almost defies categorization. What was for a long time a subject for a limited number of specialists has now moved into the mainstream of experimental and clinical immunology. In 1973 I visited the Basel Institute of Immunology and met its director, the eminent scientist and Nobel laureate Nils Jerne. When I entered his office he greeted me with the following words: “Complement, does that really exist?” I was never certain whether he wanted only to tease me or whether he sincerely believed that the complement system was an unimportant biological curiosity, a misstep of evolution. But, of course, missteps do not survive the evolutionary process. Little did I foresee the dramatic developments of recent years when Hans J. Müller-Eberhard and I started to unravel the specifics of the action of the cobra venom factor on the complement system in 1968 and defined a new pathway to its activation. An elucidation of the role of the system in diseases and its control for therapeutic reasons is now getting closer to actual realization in the clinic although many problems, in particular those of highly specificinhibition free of side effects, have still to be resolved.

Origin and Evolution of the Vertebrate Immune System

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Publisher : Springer Science & Business Media
ISBN 13 : 3642596746
Total Pages : 324 pages
Book Rating : 4.6/5 (425 download)

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Book Synopsis Origin and Evolution of the Vertebrate Immune System by : L. Du Pasquier

Download or read book Origin and Evolution of the Vertebrate Immune System written by L. Du Pasquier and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: The comparative approach to immunology can be traced to the era of Pasteur and Metchnikov in which observations regarding foreign recognition in invertebrates was a factor in the develop ment of the principal concepts that created the foundation of what now is the broad field of immunology. With each major experimental and conceptual breakthrough, the classical, albeit essential, question has been asked "are the immune systems of phylogenetically primitive vertebrates and invertebrates similar to that of mammals?" Somewhat surprisingly for the jawed verte brates, the general answer has been a qualified form of "yes", whereas for agnathans and invertebrate phyla it has been "no" so far. The apparent abruptness in the appearance of the immune system of vertebrates is linked to the introduction of the somatic generation of the diversity of its antigen specific receptors. Therefore the questions regarding the origin and evolution of the specific immune system revolve around this phenomenon. With respect to the origin of the system (aside from the or igin of the rearranging machinery itself, the study of which is still in its infancy) one can ask questions about the cellular and mo lecular contexts in which the mechanism was introduced.

The Third Component of Complement

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Publisher : Springer Science & Business Media
ISBN 13 : 3642749771
Total Pages : 254 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis The Third Component of Complement by : John D. Lambris

Download or read book The Third Component of Complement written by John D. Lambris and published by Springer Science & Business Media. This book was released on 2013-03-12 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third component of complement, C3, is one of the most versatile proteins and an important participant in immune surveillance and immune response pathways. Its multifunctio nality is based on its ability to interact specifically with multiple serum complement proteins, cell surface receptors, and mem brant;-associated regulatory proteins. One of its most intriguing strategies of interaction with cell surfaces is the covalent binding of activated C3 through the internal thioester. The field has expanded over the past 10 years and a wealth of information has accumulated. C3 from various species and many of the human C3 binding proteins have been cloned and expressed. Numerous cellular responses mediated by the diffe rent fragments of C3 have been described. The findings that C3 interacts in a ligand-receptor-like fashion with proteins of nonself origin such as the gC of herpes simplex virus, a 70-kDa protein from Candida albicans, proteins from Epstein-Barr virus, etc. has opened a new field of investigation. The papers assembled in this volume summarize the wealth of data on the various aspects of the C3 interactions; together they bring to the reader new information on the chemistry, molecular gene tics, biology, and pathophysiology of C3 and C3-binding proteins. Emphasis is given to structural features as they relate to functions. Spring 1989 JOHN D. LAMBRIS, HANS J. MULLER-EBERHARD Table of Contents J. E. VOLANAKIS: Participation of C3 and Its Ligands in Complement Activation . . . . . . . . . . . 1 S. R. BARNUM, G. FEY, and B. F. TACK: Biosynthesis and Genetics of C3 . . . . . . . . . . . . .

Complement in Health and Disease

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Publisher : Springer Science & Business Media
ISBN 13 : 9401122148
Total Pages : 385 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis Complement in Health and Disease by : K. Whaley

Download or read book Complement in Health and Disease written by K. Whaley and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the first edition of Complement in Health and Disease was published in 1986, significant advances have been made. The cDNAs for all of the components and some of the receptors have been cloned and sequenced. The chromosomal localization and the structural organization of a number of these genes have now been determined. These advances are now facilitating research into the structure of the complement proteins, the nature of the complement deficiency syndromes, the regulation of complement gene expression and the role of complement in different diseases. This edition contains contributions from both basic and clinical scientists in a format which we hope will appeal to both immunologists and physicians who wish to know more about this fascinating and important host defence system. The introductory chapter by John Weiler presents a historical background to research on the complement system and describes the biochemical events occurring during activation of the system. In Chapter 2 Alastair Dodds and Tony Day discuss the phylogeny and evolution of the complement system. The techniques of protein chemistry and molecular biology have provided powerful insights into the modular structure of complement proteins and the evolution of the complement system. The structure and organisation of the complement genes is described in Chapter 3 by Ken Reid and Duncan Campbell. This chapter describes the modular structure of the complement proteins and some of the mutations which are responsible for deficiencies of individual components.

Immunobiology of the Shark

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Publisher : CRC Press
ISBN 13 : 1466595744
Total Pages : 328 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Immunobiology of the Shark by : Sylvia L. Smith

Download or read book Immunobiology of the Shark written by Sylvia L. Smith and published by CRC Press. This book was released on 2014-12-04 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunity studies in sharks over the past three decades have produced some remarkable discoveries. If one message rings true, it is that alternative animal model systems, such as sharks and their relatives, have contributed very substantially to a better understanding of the development evolution of our own immune system. Immunobiology of the Shark describes the cellular, genetic, and molecular specifics of immune systems in sharks. Diverse approaches were employed to study the immunobiology of the shark from basic microscopic observations to detailed genome annotation. The book also raises a series of fascinating questions, which can be addressed experimentally using today’s technology. This book will be a valuable resource for mainstream immunologists, comparative immunologists, geneticists, ecologists, evolutionary biologists, and investigators engaged in shark research. The book also aims to illustrate the magnificence of these animals as model systems and underscores the importance of their study to further understand their complex, and often enigmatic, biology.

Fungal Immunology:

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Publisher : Springer Science & Business Media
ISBN 13 : 0387254455
Total Pages : 506 pages
Book Rating : 4.3/5 (872 download)

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Book Synopsis Fungal Immunology: by : Paul L. Fidel

Download or read book Fungal Immunology: written by Paul L. Fidel and published by Springer Science & Business Media. This book was released on 2006-04-09 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive review of all known immune mechanisms for medically important fungal pathogens from the organ perspectives of the human body. This authoritative guide is organized by organ system, as one particular fungus can have several different effects.

Military Strategies for Sustainment of Nutrition and Immune Function in the Field

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Publisher : National Academies Press
ISBN 13 : 0309173183
Total Pages : 722 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Military Strategies for Sustainment of Nutrition and Immune Function in the Field by : Institute of Medicine

Download or read book Military Strategies for Sustainment of Nutrition and Immune Function in the Field written by Institute of Medicine and published by National Academies Press. This book was released on 1999-05-13 with total page 722 pages. Available in PDF, EPUB and Kindle. Book excerpt: Every aspect of immune function and host defense is dependent upon a proper supply and balance of nutrients. Severe malnutrition can cause significant alteration in immune response, but even subclinical deficits may be associated with an impaired immune response, and an increased risk of infection. Infectious diseases have accounted for more off-duty days during major wars than combat wounds or nonbattle injuries. Combined stressors may reduce the normal ability of soldiers to resist pathogens, increase their susceptibility to biological warfare agents, and reduce the effectiveness of vaccines intended to protect them. There is also a concern with the inappropriate use of dietary supplements. This book, one of a series, examines the impact of various types of stressors and the role of specific dietary nutrients in maintaining immune function of military personnel in the field. It reviews the impact of compromised nutrition status on immune function; the interaction of health, exercise, and stress (both physical and psychological) in immune function; and the role of nutritional supplements and newer biotechnology methods reported to enhance immune function. The first part of the book contains the committee's workshop summary and evaluation of ongoing research by Army scientists on immune status in special forces troops, responses to the Army's questions, conclusions, and recommendations. The rest of the book contains papers contributed by workshop speakers, grouped under such broad topics as an introduction to what is known about immune function, the assessment of immune function, the effect of nutrition, and the relation between the many and varied stresses encountered by military personnel and their effect on health.

The Evolution of the Immune System

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Publisher : Academic Press
ISBN 13 : 012802013X
Total Pages : 384 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis The Evolution of the Immune System by : Davide Malagoli

Download or read book The Evolution of the Immune System written by Davide Malagoli and published by Academic Press. This book was released on 2016-05-24 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Evolution of the Immune System: Conservation and Diversification is the first book of its kind that prompts a new perspective when describing and considering the evolution of the immune system. Its unique approach summarizes, updates, and provides new insights on the different immune receptors, soluble factors, and immune cell effectors. - Helps the reader gain a modern idea of the evolution of the immune systems in pluricellular organisms - Provides a complete overview of the most studied and hot topics in comparative and evolutionary immunology - Reflects the organisation of the immune system (cell-based, humoral [innate], humoral [adaptive]) without introducing further and misleading levels of organization - Brings concepts and ideas on the evolution of the immune system to a wide readership

The Human Complement System in Health and Disease

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Publisher : CRC Press
ISBN 13 : 9780824798987
Total Pages : 672 pages
Book Rating : 4.7/5 (989 download)

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Book Synopsis The Human Complement System in Health and Disease by : John E. Volanakis

Download or read book The Human Complement System in Health and Disease written by John E. Volanakis and published by CRC Press. This book was released on 1998-02-25 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt: This authoritative, single-source reference provides comprehensive examinations of the complement system-offering recent findings in basic science on the structure, biology, physiology, and pathophysiology of complement proteins and the latest therapeutic approaches towards the control of complement-mediated diseases. Written by over 40 international experts from North America, Europe, and Asia, The Human Complement System in Health and Disease describes the molecular architecture of the complement system details the structure of complement genes discusses gene organization as well as the topology and chemistry of ligand-binding sites and catalytic centers of complement proteins analyzes complement organization and activation, including phylogeny and the newly discovered lectin pathway elucidates the regulation of complement gene expression and the structure and function of bioactive peptides explicates opsonic and immunoregulatory properties of complement fragments, endothelial responses, and interactions with viruses and bacteria and more!

Complement Regulatory Proteins

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Publisher : Academic Press
ISBN 13 : 0080529569
Total Pages : 397 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Complement Regulatory Proteins by : B. Paul Morgan

Download or read book Complement Regulatory Proteins written by B. Paul Morgan and published by Academic Press. This book was released on 1999-02-18 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: From small beginnings in the early 1970s, the study of complement regulatory proteins has grown in the last decade to the point where it dominates the complement field. This growth has been fueled by the discovery of new regulators, the cloning of old and new regulators, the discovery that many of the regulators are structurally and evolutionarily related to each other and the development of recombinant forms for use in therapy. There are now more proteins known to be involved in controlling the complement system than there are components of the system and the list continues to grow. The time is ripe for a comprehensive review of our current knowledge of these intriguing proteins. This book does just that. The first few chapters discuss the "nuts-and-bolts" of the complement regulators, describing their structures, functional roles and modes of action. The roles of the complement regulators in vivo are then described, focusing on the consequences of deficiency, roles in the reproductive system, interactions with pathogens and exploitation for therapy. The interesting developments in defining the complement regulators expressed in other species are also discussed. The book is written as a monograph, albeit by two people. The text is as readable as possible without compromising on scientific accuracy and completeness. The conversational style very evident in some sections is deliberate! Placing all references in a single bibliography at the end of the text further improves readability. The reader will go to the book to discover a specific fact but be persuaded to read more and derive pleasure from the process. The authors' enthusiasm for the subject comes over strongly in the text, and this enthusiasm proves infectious. - Complement regulators--structure, functional roles and mode of action - Comprehensive reviews of each of the individual regulators - Roles of Complement regulators in vivo,in health and disease: - Consequences of deficiency - Roles in the reproductive system - Interactions with pathogens - Exploitation for therapy - Complement regulators in other species