Immune Responses in the Nervous System

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Author :
Publisher : Taylor & Francis
ISBN 13 :
Total Pages : 264 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Immune Responses in the Nervous System by : Nancy Rothwell

Download or read book Immune Responses in the Nervous System written by Nancy Rothwell and published by Taylor & Francis. This book was released on 1995 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many molecules and mechanisms traditionally associated with the peripheral immune system have been found to be active within the central nervous system. The investigation of immune activation is a rapidly expanding field of research, particularly since it is directly related to acute neuronal damage and in degenerative disorders of the nervous system such as Alzheimer's disease and multiple sclerosis. This volume brings together a team of internationally recognized experts who address topics such as neuronal transplantation, leukocyte migration, the role of inflammation and immune responses in neurological diseases and brain injury, and the potential benefits of treatment with modulators of cytokine action. It will be of interest to all researchers and clinicians involved in the understanding, diagnosis and treatment of neuroimmune diseases.

Immune Responses in the Nervous System. Part 1

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Author :
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (641 download)

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Book Synopsis Immune Responses in the Nervous System. Part 1 by :

Download or read book Immune Responses in the Nervous System. Part 1 written by and published by . This book was released on 1992 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Immune responses in the nervous system

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Author :
Publisher :
ISBN 13 :
Total Pages : 50 pages
Book Rating : 4.:/5 (18 download)

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Book Synopsis Immune responses in the nervous system by :

Download or read book Immune responses in the nervous system written by and published by . This book was released on 1992 with total page 50 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Protective and Pathological Immune Responses in the CNS

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3662095254
Total Pages : 285 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis Protective and Pathological Immune Responses in the CNS by : B. Dietzschold

Download or read book Protective and Pathological Immune Responses in the CNS written by B. Dietzschold and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: In spite of the protection of the CNS there are situations where immune responses occur due to different disease processes. While antigen-specific cells of the adaptive immune response are not normally functional in the CNS tissue, CNS resident cells respond to infection or insult. One mechanisms is through the induction of apoptosis in virus infected neurons, which may be protective or pathogenic depending on the extent of cell death.

Induction of Central Nervous System Disease by the Adaptive Immune Response

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889453472
Total Pages : 143 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Induction of Central Nervous System Disease by the Adaptive Immune Response by : Robert Weissert

Download or read book Induction of Central Nervous System Disease by the Adaptive Immune Response written by Robert Weissert and published by Frontiers Media SA. This book was released on 2017-11-23 with total page 143 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last years it has become evident that many neurological diseases of the central nervous system (CNS) are induced by a specific adaptive immune response directed against molecules expressed on CNS-resident cells. Well-recognized examples are anti-N-Methyl-D-Aspartate Receptor (NMDAR) encephalitis which is characterized by the presence of antibodies against neuron-expressed NMDAR, or neuromyelitis optica (NMO), induced by antibodies to astrocyte-expressed aquaporin-4. Many more examples exist, and antibodies, and T or/and B cells have increasingly been associated with CNS disease. Often the symptoms of these diseases have not been typically reported to have an immune aetiology. Beside classical neurological symptoms like ataxia, vision disturbance, and motor or sensory symptoms, these can include cognitive disturbances, behavioral abnormalities, or/and epileptic seizures. Although much has been learned regarding the pathophysiology of prototypic examples of these disorders, there are still major gaps in our understanding of their biology. This may be due to the fact that they are rare diseases, and their therapies are still very limited. This research topic includes contributions addressing the analysis of the adaptive immune response driving disease including target antigens, molecular epitope mapping, and factors involved in the disease pathogenesis such as complement activation cascades, genetic and genomic regulation, as well as environmental triggers. Diagnostic criteria and methods, and treatment are also discussed. The overall aim of the volume is to review progress in our pathophysiological understanding of immune-mediated CNS disorders in order to advance diagnostic and therapeutic approaches, and ultimately improve outcomes for patients.

Immunoneurology

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Publisher : Springer Science & Business Media
ISBN 13 : 3642611915
Total Pages : 265 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Immunoneurology by : Michel Chofflon

Download or read book Immunoneurology written by Michel Chofflon and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: A considerable amount of information has been gathered in the field of immunoneurology over recent years. This knowledge about modifications in the pathways of neuroimmune diseases has enabled the development of new therapies. In this volume leading experts present the state of the art in the field, covering all aspects from basic science to the development of better therapies.

Immune Responses in the Nervous System

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Author :
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (598 download)

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Book Synopsis Immune Responses in the Nervous System by :

Download or read book Immune Responses in the Nervous System written by and published by . This book was released on 1992 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Psychoneuroimmunology, Stress, and Infection

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Author :
Publisher : CRC Press
ISBN 13 : 1000722554
Total Pages : 312 pages
Book Rating : 4.0/5 (7 download)

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Book Synopsis Psychoneuroimmunology, Stress, and Infection by : Herman Friedman

Download or read book Psychoneuroimmunology, Stress, and Infection written by Herman Friedman and published by CRC Press. This book was released on 2020-02-03 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Psychoneuroimmunology is the emerging science devoted to studying the two-way relationship between the nervous and immune systems. Psychoneuroimmunology, Stress, and Infection highlights the latest information concerning microbial infections in both man and animals as related to stress and especially stress hormones. The volume focuses on psychoneuroimmunology as it impacts the immune system in general and also the relationship between neurological events which influence susceptibility and/or resistance to infectious agents such as bacteria, fungi and viruses, as well as parasites. Prominent researchers describe the involvement of the hypothalamus-pituitary-adrenal (HPA) axis on immunity as a function of the nervous system. The text discusses hormones such as prolactin and growth hormone and steroid induced susceptibility to infection and neuropeptides, including vasoactive intestinal peptide, and substance P. The effects of catacholamines on immunity and susceptibility to infection are also covered. This reference also details the involvement of immune cells in the synthesis of neuropeptides, including hormones and endorphins, their effect on the brain as well as the effects of interleukins and tumor necrosis factor on the central nervous system. The book concludes with an interesting look at the relationship between aging, psychoneuroimmunology, and infection. Although there is much new knowledge concerning the nature and mechanism of immune responses, including the mediators involved, Psychoneuroimmunology, Stress, and Infection also presents important discussions and reviews that are long overdue and provide a major contribution to the area of biomedical knowledge in general and psychoneuroimmunology in particular.

Innate Immune Responses in CNS Inflammation

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Publisher : Frontiers Media SA
ISBN 13 : 2889717429
Total Pages : 256 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Innate Immune Responses in CNS Inflammation by : Mireia Guerau-de-Arellano

Download or read book Innate Immune Responses in CNS Inflammation written by Mireia Guerau-de-Arellano and published by Frontiers Media SA. This book was released on 2021-11-30 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Neural Plasticity and Memory

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Publisher : CRC Press
ISBN 13 : 1420008412
Total Pages : 368 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Neural Plasticity and Memory by : Federico Bermudez-Rattoni

Download or read book Neural Plasticity and Memory written by Federico Bermudez-Rattoni and published by CRC Press. This book was released on 2007-04-17 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive, multidisciplinary review, Neural Plasticity and Memory: From Genes to Brain Imaging provides an in-depth, up-to-date analysis of the study of the neurobiology of memory. Leading specialists share their scientific experience in the field, covering a wide range of topics where molecular, genetic, behavioral, and brain imaging techniq

The Brain and Host Defense

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Publisher : Elsevier
ISBN 13 : 0444535454
Total Pages : 362 pages
Book Rating : 4.4/5 (445 download)

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Book Synopsis The Brain and Host Defense by :

Download or read book The Brain and Host Defense written by and published by Elsevier. This book was released on 2009-12-24 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is now well recognized that the brain, and especially the hypothalamus, plays an important role in the regulation of immune reactions and inflammation. This book aims to review our current state of knowledge of this important field. Key historical findings are presented, and the reciprocal interactions between the brain and the immune system are examined. Particular emphasis is placed on inflammation, a critical host defense reaction that serves as an effector response for both the adaptive and innate immune systems. Mechanisms implicated in brain defense, as well as in more general host defense, are discussed. The regulatory influences of the brain on inflammatory responses are included with particular reference to the role of the hypothalamus, which is also the main director the hormonal regulation of immune/inflammatory. Gender-related differences in immune responsiveness, circadian modulator of immune responses, and evidence that behavioral conditioning (e.g. reward) of immune responses is possible are used as examples to reinforce the notion that the neuroendocrine system exerts a fundamental and complex regulatory influence on the immune system. Presents timely issues such as immunological aspects of the blood-brain-barrier and the role of inflammatory mediators in the evolution of strokes and degenerative diseases Includes analysis of the role of the brain in the adaptive responses to disease Evaluates the argument that further knowledge of the influence of the brain on the immune system will provide new insights to the pathophysiology infectious and autoimmune diseases

Handbook of Human Stress and Immunity

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Author :
Publisher : Academic Press
ISBN 13 : 1483295125
Total Pages : 436 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Handbook of Human Stress and Immunity by : Ronald Glaser

Download or read book Handbook of Human Stress and Immunity written by Ronald Glaser and published by Academic Press. This book was released on 2014-06-28 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1964, George Solomon coined the term psychoneuroimmunology. In the intervening 30 years, this term has emerged into a dynamic field of study which investigates the unique interactions between the nervous, endocrine, and immune systems. The Handbook of Human Stress and Immunity is a comprehensive reference for this dynamic new field. Focusing on how stressors impact the central nervous system and the resulting changes in immune responses, the Handbook is the first to describehow stress specifically affects human immune systems. It discusses how stress generally makes people more susceptible to infection, how personal support systems can counteract the physiological effects of stress, and how stress, or lack of stress, affects the aging process. Chapters are authored by the leading names in the field and cover such diseases as autoimmune disease, viral pathogenesis, herpes, HIV, and AIDS.

Janeway's Immunobiology

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Author :
Publisher : Garland Science
ISBN 13 : 9780815344575
Total Pages : pages
Book Rating : 4.3/5 (445 download)

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Book Synopsis Janeway's Immunobiology by : Kenneth Murphy

Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

The Immune System and the Developing Brain

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Publisher : Morgan & Claypool Publishers
ISBN 13 : 1615043519
Total Pages : 131 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis The Immune System and the Developing Brain by : Jaclyn M. Schwarz

Download or read book The Immune System and the Developing Brain written by Jaclyn M. Schwarz and published by Morgan & Claypool Publishers. This book was released on 2012 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt: The developing brain is exquisitely sensitive to both endogenous and exogenous signals which direct or significantly alter the developmental trajectory of cells, neural circuits, and associated behavioral outcomes for the life of the individual. Contrary to initial dogma that the brain is one of the few organs within the body that is immune-privileged, evidence indicates that the immune system has a critical role in brain function during development as well as during sickness and health in adulthood. Microglia are the primary immune cells within the brain, and they are in constant communication with the peripheral immune system and surrounding cell types within the brain. We describe the important role of the immune system, including microglia, during brain development, and discuss some of the many ways in which immune activation during early brain development can affect the later-life outcomes of neural function, immune function, and cognition. Growing evidence indicates that there is a strong link between many neuropsychiatric disorders and immune dysfunction, with a distinct etiology in neurodevelopment. Thus, understanding the role of the immune system and immune activation during the critical period of brain development is a necessary step toward understanding the potential origins of these devastating disorders. Table of Contents: Introduction / The Immune Response / Brain-Immune Communication / Microglia Are Immune Cells of the Brain / The Functional Role of Microglia and Immune Molecules in Neurodevelopment / Early-Life Programming of Brain and Behavior: A Critical Role for the Immune System / Commonly Used Models of Early Life Immune Activation in the Rodent / Early Life Immune Activation and Cognitive Impairment in Adulthood / Mechanisms Underlying the Enduring Changes in Neuroimmune Function Caused by Early Life Infection / Toll-Like Receptors and Immune Activation During Early Brain Development / Environmental Triggers of TLR Activation: Long-Term Programming of Brain and Behavior / Future Directions to Understanding Immune Function and Brain Development / References

Immune and Inflammatory Responses in the Nervous System

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Author :
Publisher :
ISBN 13 :
Total Pages : 202 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Immune and Inflammatory Responses in the Nervous System by : Nancy Rothwell

Download or read book Immune and Inflammatory Responses in the Nervous System written by Nancy Rothwell and published by . This book was released on 2002 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new edition covers recent advances in understanding immunological and inflammatory responses in the nervous system, research driven by the potential to use knowledge of the molecules and mechanisms involved to intervene in, and arrest, neurodegenerative disease processes.Immune and Inflammatory Responses in the Nervous System covers developmental aspects of immune/inflammatory responses in the CNS, basic aspects of glial function, as well as inflammatory mediators, their mechanisms of action, clinical importance and sites of infection. There is also coverage of themajor diseases of the CNS, including stroke, brain injury, multiple sclerosis and Alzheimer's disease. Throughout, the focus is on the underlying basic neuroscience, clinical relevance and the potential for therapeutic interventions.This will be an invaluable aid to understanding and improving the diagnosis of neuroimmune diseases and determining therapeutic measures.The contributors are all leading experts in the field and the content will be of interest to neuroscientists, neurologists, neuropathologists, neurosurgeons and immunologists.

Insect Immunology

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Publisher : Academic Press
ISBN 13 : 0080556337
Total Pages : 367 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Insect Immunology by : Nancy E. Beckage

Download or read book Insect Immunology written by Nancy E. Beckage and published by Academic Press. This book was released on 2011-04-28 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work is the first book-length publication on the topic of insect immunology since 1991, complementing earlier works by offering a fresh perspective on current research. Interactions of host immune systems with both parasites and pathogens are presented in detail, as well as the genomics and proteomics, approaches which have been lacking in other publications. Beckage provides comprehensive coverage of topics important to medical researchers, including Drosophila as a model for studying cellular and humoral immune mechanisms, biochemical mediators of immunity, and insect blood cells and their functions. Encompasses the most important topics of insect immunology including mechanisms, genes, proteins, evolution and phylogeny Provides comprehensive coverage of topics important to medical researchers including Drosophila as a model for studying cellular and humoral immune mechanisms, biochemical mediators of immunity, and insect blood cells and their functions Most up-to-date information published with contributions from international leaders in the field

Neuroimmune Pharmacology

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Author :
Publisher : Springer
ISBN 13 : 3319440225
Total Pages : 1045 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Neuroimmune Pharmacology by : Tsuneya Ikezu

Download or read book Neuroimmune Pharmacology written by Tsuneya Ikezu and published by Springer. This book was released on 2016-12-22 with total page 1045 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of Neuroimmune Pharmacology bridges the disciplines of neuroscience, immunology and pharmacology from the molecular to clinical levels with particular thought made to engage new research directives and clinical modalities. Bringing together the foremost field authorities from around the world, Neuroimmune Pharmacology will serve as an invaluable resource for the basic and applied scientists of the current decade and beyond.