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Immediate Early Genes In The Central Nervous System
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Book Synopsis Immediate-Early Genes in the Central Nervous System by : T.R. Tölle
Download or read book Immediate-Early Genes in the Central Nervous System written by T.R. Tölle and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 171 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immediate-early genes are believed to be involved in the neuron's ability to con vert short-term synaptic stimulation into long-lasting responses and thus contribute to the adaptive alterations involved in neuronal plasticity. Cellular immediate-early genes share a close structural homology with some viral oncogenes. Recent advances in cellular biology have identified the activation and deactivation of immediate-early genes as molecular mechanisms to control regulated and deregulated growth, cellular differentiation and development. In this view immediate-early genes may function as third messengers in a stimulus transcription cascade transferring extracellular information into changes in target gene transcription, thereby changing the phenotype of neurons. Immediate-Early Genes in the Central Nervous System provides a comprehensive up-to-date overview of current methodology in the research of immediate-early genes and includes a wide range of neurobiological topics, such as regeneration, memory formation, epilepsia and nociception. The contributors to this book have been selected from among the leading experts in their field of research. T.R. TOLLE J. SCHADRACK W. ZIEGLGANSBERGER Contents Immediate-early genes -how immmediate and why early? G./. Evan .............................................. . Immediate-early gene activation as a window on mechanism in the nervous system S.P. Hunt, L.A. McNaughton, R. Jenkins, and W. Wisden. . . . . . . . . .. . . . 18 of immediate-early genes during Differential expression synaptic plasticity, seizures and brain injury suggests specific functions for these molecules in brain neurons M. Dragunow . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. . . . 35 . . . . . . . . . .
Book Synopsis Immediate Early Genes and Inducible Transcription Factors in Mapping of the Central Nervous System Function and Dysfunction by : L. Kaczmarek
Download or read book Immediate Early Genes and Inducible Transcription Factors in Mapping of the Central Nervous System Function and Dysfunction written by L. Kaczmarek and published by Gulf Professional Publishing. This book was released on 2002-07 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings together information about the most widely studied IEG/ITF involved in a variety of neuronal activation. Written by a prominent group of authors, it attempts to unravel the complexity of the phenomena of gene expression in the central nervous system.
Book Synopsis Immediate Early Genes and Inducible Transcription Factors in Mapping of the Central Nervous System Function and Dysfunction by :
Download or read book Immediate Early Genes and Inducible Transcription Factors in Mapping of the Central Nervous System Function and Dysfunction written by and published by . This book was released on 2002 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Immediate Early Genes in Sensory Processing, Cognitive Performance and Neurological Disorders by : Raphael Pinaud
Download or read book Immediate Early Genes in Sensory Processing, Cognitive Performance and Neurological Disorders written by Raphael Pinaud and published by Springer Science & Business Media. This book was released on 2006-11-22 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a compilation of the most up-to-date literature on the topic of immediate early genes (IEGs). It reviews and details experiments and theories that challenge the reader to expand their view on how IEG research is currently being used to advance our understanding of static and active brain circuits. In addition, the book explores roles of IEGs in clinical neuropathology.
Book Synopsis Involvement of the Immediate Early Genes NGFI-A and Arc in Enriched Environment-induced Plasticity in the Central Nervous System by : Raphael Ribeiro Pinaud
Download or read book Involvement of the Immediate Early Genes NGFI-A and Arc in Enriched Environment-induced Plasticity in the Central Nervous System written by Raphael Ribeiro Pinaud and published by . This book was released on 2001 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: The phenomenon of neural plasticity has been postulated to reflect changes in central nervous system circuitry in order to optimize the collection and/or interpretation of environmental information. The expression of immediate early genes (EEGs) is the first genomic response to environmental cues for change. Many EEGs act as transcription factors, in which case they could regulate the genetic mechanisms involved in more stable changes. Generally, long-term changes in circuit performance are mediated by proteins that result from the expression of late genes. The IEGs, nerve growth factor induced gene-A (NGFI-A) and activity regulated cytoskeletal protein (Arc) are currently under investigation as candidate-plasticity genes. NGFI-A is a nuclear protein that serves as a transcription factor for the Synapsins, a family of genes that has been strongly implicated as markers for neural plasticity. Arc has been hypothesized to mediate locally executed dendritic reconfigurations in response to changes in activity levels. In the present thesis, the response profiles for both these IEGs, along with the late genes growth associated protein-43 (GAP-43) and synapsin I, were evaluated for their role in mediating neural plasticity.
Book Synopsis Immediate Early Gene Expression in Plasticity and Pathology in the Central Nervous System by : Aileen J. Anderson
Download or read book Immediate Early Gene Expression in Plasticity and Pathology in the Central Nervous System written by Aileen J. Anderson and published by . This book was released on 1995 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Role of "Immediate Early Genes" in the Central Nervous System of Susceptible and Resistant Mouse Strains During Theiler's Murine Encephalomyelitis by : Ingo Gerhauser
Download or read book The Role of "Immediate Early Genes" in the Central Nervous System of Susceptible and Resistant Mouse Strains During Theiler's Murine Encephalomyelitis written by Ingo Gerhauser and published by . This book was released on 2007 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :Raphael Pinaud Publisher :National Library of Canada = Bibliothèque nationale du Canada ISBN 13 :9780612665842 Total Pages :242 pages Book Rating :4.6/5 (658 download)
Book Synopsis Involvement of the Immediate Early Genes NGFI-A and Arc in Enriched Environment-induced Plasticity in the Central Nervous System [microform] by : Raphael Pinaud
Download or read book Involvement of the Immediate Early Genes NGFI-A and Arc in Enriched Environment-induced Plasticity in the Central Nervous System [microform] written by Raphael Pinaud and published by National Library of Canada = Bibliothèque nationale du Canada. This book was released on 2001 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Neurotransmitter-regulated Expression of Immediate-early Genes Within the Nervous System by : Paul Hughes
Download or read book Neurotransmitter-regulated Expression of Immediate-early Genes Within the Nervous System written by Paul Hughes and published by . This book was released on 1994 with total page 626 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Handbook of Chemical Neuroanatomy: Immediate early genes and inducible transcription factors in mapping ot the central nervous system function and dysfunction by : Anders Björklund
Download or read book Handbook of Chemical Neuroanatomy: Immediate early genes and inducible transcription factors in mapping ot the central nervous system function and dysfunction written by Anders Björklund and published by . This book was released on 1983 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Mouse Nervous System by : Charles Watson
Download or read book The Mouse Nervous System written by Charles Watson and published by Academic Press. This book was released on 2011-11-28 with total page 815 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Mouse Nervous System provides a comprehensive account of the central nervous system of the mouse. The book is aimed at molecular biologists who need a book that introduces them to the anatomy of the mouse brain and spinal cord, but also takes them into the relevant details of development and organization of the area they have chosen to study. The Mouse Nervous System offers a wealth of new information for experienced anatomists who work on mice. The book serves as a valuable resource for researchers and graduate students in neuroscience. Systematic consideration of the anatomy and connections of all regions of the brain and spinal cord by the authors of the most cited rodent brain atlases A major section (12 chapters) on functional systems related to motor control, sensation, and behavioral and emotional states A detailed analysis of gene expression during development of the forebrain by Luis Puelles, the leading researcher in this area Full coverage of the role of gene expression during development and the new field of genetic neuroanatomy using site-specific recombinases Examples of the use of mouse models in the study of neurological illness
Book Synopsis Microinjection by : Juan Carlos Lacal
Download or read book Microinjection written by Juan Carlos Lacal and published by Birkhäuser. This book was released on 2013-12-01 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: This manual describes the methodology and applications of microinjection, a powerful technique for transposing material into living cells through needle injection. Information is presented on the techniques principles, the required equipment, preparation of receiving cells and injected material, and the analysis of results. Detailed protocols for a wide range of applications in different cellular systems are included. A large part of the book is also dedicated to the Xenopus laevis oocyte system.
Book Synopsis Genetic Manipulation of the Nervous System by :
Download or read book Genetic Manipulation of the Nervous System written by and published by Elsevier. This book was released on 1995-11-24 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroscience Perspectives provides multidisciplinary reviews of topics in one of the most diverse and rapidly advancing fields in the life sciences. Whether you are a new recruit to neuroscience, or an established expert, look to this series for 'one-stop' sources of the historical, physiological, pharmacological, biochemical, molecular biological and therapeutic aspects of chosen research areas. The recent development of Gene Therapy procedures which allow specific genes to be delivered to human patients who lack functional copies of them is of major therapeutic importance. In addition such gene delivery methods can be used in other organisms to define the function of particular genes. These studies are of particular interest in the nervous system where there are many incurable diseases like Alzheimer's and Parkinson's diseases which may benefit from therapies of this kind. Unfortunately gene delivery methods for use in the nervous system have lagged behind those in other systems due to the fact that the methods developed in other systems are often not applicable to cells like neurons which do not divide. This book discusses a wide range of methods which have now been developed to overcome these problems and allow safe and efficient delivery of particular genes to the brain. Methods discussed include virological methods, physical methods (such as liposomes) and the transplantation of genetically modified cells. In a single volume therefore this book provides a complete view of these methods and indicates how they can be applied to the development of therapies for treating previously incurable neurological disorders.
Book Synopsis Gene Expression in the Central Nervous System by : Albert C. H. Yu
Download or read book Gene Expression in the Central Nervous System written by Albert C. H. Yu and published by . This book was released on 1995 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Gene Expression in the Central Nervous System by :
Download or read book Gene Expression in the Central Nervous System written by and published by . This book was released on 1995 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Characterization of NGFI-A and the Dendritic Immediate-early Gene Arc in the Hippocampus of Rapidly Kindled Rats by : Marsha Rae Penner
Download or read book Characterization of NGFI-A and the Dendritic Immediate-early Gene Arc in the Hippocampus of Rapidly Kindled Rats written by Marsha Rae Penner and published by . This book was released on 2001 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuronal plasticity in the adult central nervous system is essential for dealing with environmental stimuli and injury-related changes. Kindling refers to the process whereby repeated, electrical stimulations of the brain leads to long-lasting or permanent changes in brain function. Kindling is typically established over several weeks using once daily stimulation, so called traditional kindling. It has been hypothesized that kindling may also be established within hours using different stimulation parameters, so called rapid kindling. However, studies investigating this possibility have provided conflicting results. In addition, while there has been intensive investigation into the mechanisms that mediate the pathological plasticity associated with kindling, much still remains to be elucidated. The expression of immediate-early genes (IEGs) is considered the first genomic response to underlie plastic changes in the CNS. Nerve growth factor induced gene-A (NGFI-A) and activity regulated cytoskeletal protein (ARC) are IEGs whose expression has been implicated in the transition from short-term to long-term synaptic plasticity. Based on these findings, the ability of rapid kindling to establish a kindled state and the response profiles of NGFI-A and ARC associated with rapid kindling were assessed.
Book Synopsis From Neurons to Neighborhoods by : National Research Council
Download or read book From Neurons to Neighborhoods written by National Research Council and published by National Academies Press. This book was released on 2000-11-13 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: How we raise young children is one of today's most highly personalized and sharply politicized issues, in part because each of us can claim some level of "expertise." The debate has intensified as discoveries about our development-in the womb and in the first months and years-have reached the popular media. How can we use our burgeoning knowledge to assure the well-being of all young children, for their own sake as well as for the sake of our nation? Drawing from new findings, this book presents important conclusions about nature-versus-nurture, the impact of being born into a working family, the effect of politics on programs for children, the costs and benefits of intervention, and other issues. The committee issues a series of challenges to decision makers regarding the quality of child care, issues of racial and ethnic diversity, the integration of children's cognitive and emotional development, and more. Authoritative yet accessible, From Neurons to Neighborhoods presents the evidence about "brain wiring" and how kids learn to speak, think, and regulate their behavior. It examines the effect of the climate-family, child care, community-within which the child grows.
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