Ikaros

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Author :
Publisher : Page Publishing Inc
ISBN 13 : 1642149780
Total Pages : 274 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Ikaros by : Harley Brattain

Download or read book Ikaros written by Harley Brattain and published by Page Publishing Inc. This book was released on 2022-05-04 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the world of Deja Pascal aEUR" one of beauty, hope, and endless perfectionaEUR"lurked a darkness. The bloody, cold reality of World War II and its unnumbered shattered lives lay just beyond the trees of their home. Death and loss were unreal to her in the blissful isolation of French hillside until the day a black car carrying a man in a black suit arrived. Watching from a hiding place in the woods, Deja looked on hopelessly as her parents were thrown into the back of a Nazi truck. Pallid and weak, her father, Luc, returned two years later. She never saw her mother again. Compounding the loss of her mother and the effect of the camps on her father, Deja lost her closest friend and confidant in college some years later. Deja's spirit broke from loss, and she became depressed, finally culminating in her taking her own life. Despondent and without hope, Luc, a scientist by trade, decided to use his greatest invention, a device he coined, the Spirit Box, to save her soul from death and bring her back to the world as a timeaEUR"traveling, robotic being suffering for a second chance at a real life, one with meaning and love. Adventuring through ancient Greece, native America, and other fantastical times, she evolved into something more, something greateraEUR"a spirit with purpose. The Deja who left the world a saddened young woman came back strong and potent. She came back as Ikaros.

The Flight of Ikaros

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Author :
Publisher : Paul Dry Books
ISBN 13 : 158988261X
Total Pages : 280 pages
Book Rating : 4.5/5 (898 download)

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Book Synopsis The Flight of Ikaros by : Kevin Andrews

Download or read book The Flight of Ikaros written by Kevin Andrews and published by Paul Dry Books. This book was released on 2010-05-01 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: "One of the great and lasting books about Greece."—Patrick Leigh Fermor "An intense and compelling account of an educated, sensitive archaeologist wandering the back country during the civil war. Half a century on, still one of the best books on Greece as it was before 'development.'"—The Rough Guide to the Greek Islands "He also is in love with the country…but he sees the other side of that dazzling medal or moon…If you want some truth about Greece, here it is."—Louis MacNeice, The Observer "One of the best and most honest books about the modern Greeks."—E. R. Dodds "Kevin Andrews experienced the dangers of the countryside during the civil war. The Flight of Ikaros, the book he produced from his travels, remains not only one of the greatest we have about postwar Greece—memorializing a village culture that has almost vanished—but also one of the most moving accounts I have ever read of people caught up in political turmoil…Flightwas first published in 1959 and last reprinted by Penguin in 1984. For too many years, this rare account has languished out of print."—Wall Street Journal In 1947, at the age of twenty-three, Kevin Andrews received a Fulbright Fellowship to study medieval fortresses in the Peloponnese. Andrews spent the long summers of 1948 to 1951 traveling through the region and the winters writing in Athens. This opportunity to travel through little-frequented areas during Greece’s postwar civil war—and before the advent of tourism, industrialization, or easy communications—brought Andrews into immediate contact with village populations, shepherd clans, and the paramilitary vigilantes who kept their own kind of order in the provinces, as well as with the displaced peasants of the Athenian slums. The close experience of all these lives took shape in The Flight of Ikaros, first published in 1959. Paul Dry Books is pleased to return to print this modern travel classic.

Transcription Factors

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Publisher : John Wiley & Sons
ISBN 13 : 0471461067
Total Pages : 640 pages
Book Rating : 4.4/5 (714 download)

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Book Synopsis Transcription Factors by : Katya Ravid

Download or read book Transcription Factors written by Katya Ravid and published by John Wiley & Sons. This book was released on 2003-11-04 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transcription Factors Normal and Malignant Development of Blood Cells Katya Ravid and Jonathan Licht The role of transcription factors in activating specific genes in blood cells is an important facet of hematopoiesis. Equally important, however, is the pursuit of genes rearranged and aberrantly activated in leukemias (blood malignancies). Transcription Factors: Normal and Malignant Development of Blood Cells focuses on those major transcription factors involved in activation of lineage-specific gene expression during normal versus malignant development of specific blood lineages, as revealed from gene promoter studies, knockout of transcription factors in mice models, and the identification and characterization of chromosomal rearrangement in human blood leukemias. This complete digest of current transcription factor data offers comprehensive coverage of the myriad of transcription factors in blood cell development, composed by established experts in the field. In addition to updating the reader on the connection between chromosomal translocations involving transcription factors and cellular transformation leading to leukemia, Transcription Factors also reviews such subjects as: * Transcription factors and the megakaryocytic, myeloid, and erythroid lineages * Leukemias due to chromosomal translocations involving gene encoding transcription factors * Oncogenesis and hematopoiesis * In vivo studies of transcription factors implicated in hematopoiesis * And much more Appealing to both the researcher and the clinician in the field of hematology, Transcription Factors is a timely presentation of cell lineage development and sheds light on the processes involved in the development of specific leukemias. Providing insight into the study of transcription factors, readers will gain an understanding of mechanisms that lead to normal lineage commitment and terminal differentiation.

Hematopoiesis

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Author :
Publisher : Oxford University Press
ISBN 13 : 9780199771752
Total Pages : 864 pages
Book Rating : 4.7/5 (717 download)

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Book Synopsis Hematopoiesis by : Leonard I. Zon

Download or read book Hematopoiesis written by Leonard I. Zon and published by Oxford University Press. This book was released on 2001-04-12 with total page 864 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hematopoiesis, or the process of blood formation, has been extensively studied at both basic and clinical levels. Human diseases such as thalassemia, immunodeficiency, and leukemia represent defects in this process. Approaches to treat these disorders have required a basic understanding of the biology of blood cells. For instance, hemapoietic stem cell replacement or bone marrow transplantation has been used to ameliorate disease. This volume focuses on hematopoiesis at a cellular and molecular level, and establishes the basis for clinical manipulation of hematopoietic cells for therapeutic benefit. In Part I, the cellular characteristics of progenitors and stem cells are explored. Emphasis is placed on purification of stem cells and both in vitro and in vivo assays. The regulation of normal and leukemis stem cells is illustrated. An excellent discussion of potential use of these cells for gene therapy concludes this section. Hemapoiesis is easily studied during embryogenesis. Part II develops the concept of the waves of hemapoiesis during development. Comparative hematology is making a major comeback as a field in the 1990's. One hope is that general principles of hematopoiesis will be established by studying many models and systems. Part III delves into critical factors that regulate hematopoiesis, including both intracellular and extracellular signals. Part IV and V describe lineage programs for myeloid and lymphoid lineages. These chapters are meant to be illustrative of the different cell fates, but are not exhaustive. Part VI examines the genetics of hematopoisis, particularly in animal models. The hematopoietic system is in constant contact with stromal cells and endothelial cells during development and in the adult. Evidence suggests that endothelial cells and blood cells may arise from a common progenitor, the hemangioblast. Part VII and VIII discuss the stromal and endothelial cells with the emphasis on their interaction with hematopoietic cells.

Yearbook of Pediatric Endocrinology 2005

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Author :
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805579969
Total Pages : 242 pages
Book Rating : 4.8/5 (55 download)

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Book Synopsis Yearbook of Pediatric Endocrinology 2005 by : Jean-Claude Carel

Download or read book Yearbook of Pediatric Endocrinology 2005 written by Jean-Claude Carel and published by Karger Medical and Scientific Publishers. This book was released on 2005-01-01 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: The body of knowledge in most medical specialties is rapidly expanding, making it virtually impossible to follow all advances in clinical and basic sciences that are relevant to a given field. This is particularly true in pediatric endocrinology, at the cross-road of pediatrics, endocrinology, development and genetics. The 2005 Yearbook of Pediatric Endocrinology brings you a selection of articles that report the year's breakthrough developments in basic sciences and evidence-based new knowledge in clinical research and clinical practice that are relevant to the field. Covering the medical literature published from July 2004 through June 2005, the editors and associate editors selected from several thousand papers those that brought the most meaningful new information, summarized them and provided comments to put them into perspective. The papers are classified into those that identify new genes involved in diseases, new hormones, concepts revised or recentered, important observations for clinical practice, large-scale clinical trials, new mechanisms, new paradigms, important review articles, new fears and new hopes. This is the second volume of the Yearbook of Pediatric Endocrinology, and it is already regarded as a tradition by experts in the field. The Yearbook of Pediatric Endocrinology is endorsed by the European Society for Paediatric Endocrinology (ESPE). We hope that the Yearbook of Pediatric Endocrinology 2005 will help busy clinicians and scientists, pediatric endocrinologists, and also pediatricians and endocrinologists keep informed on new advances in our field.

T-Cell Leukemia

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 9533074000
Total Pages : 247 pages
Book Rating : 4.5/5 (33 download)

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Book Synopsis T-Cell Leukemia by : Olga Babusikova

Download or read book T-Cell Leukemia written by Olga Babusikova and published by BoD – Books on Demand. This book was released on 2011-10-26 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this book is to provide a comprehensive review of the scientific advances in T-cell malignancies and to highlight the most relevant findings that will help the reader understand both basic mechanisms of the disease and future directions that are likely to lead to novel therapies. In order to assure a thorough approach to these problems, contributors include basic scientists, translational researchers and clinicians who are experts in this field. Thus, the target audience for this book includes both basic scientists who will use this book as a review of the advances in our fundamental knowledge of the molecular mechanisms of T-cell malignancies, as well as clinicians who will use this book as a tool to understand rationales for the development of novel treatments for these diseases.

Zinc Finger Proteins

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 0387274219
Total Pages : 291 pages
Book Rating : 4.3/5 (872 download)

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Book Synopsis Zinc Finger Proteins by : Shiro Iuchi

Download or read book Zinc Finger Proteins written by Shiro Iuchi and published by Springer Science & Business Media. This book was released on 2007-03-06 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the early 1980s, a few scientists started working on a Xenopus transcription factor, TFIIIA. They soon discovered a novel domain associated with zinc, and named this domain "zinc finger. " Th e number of proteins with similar zinc fingers grew quickly and these proteins are now called C2H2, Cys2His2 or classical zinc finger proteins. To date, about 24,000 C2H2 zinc finger proteins have been recognized. Approximately 700 human genes, or more than 2% of the genome, have been estimated to encode C2H2 finger proteins. From the beginning these proteins were thought to be numerous, but no one could have predicted such a huge number. Perhaps thousands of scientists are now working on C2H2 zinc finger proteins fi-om variou s viewpoints. This field is a good example of how a new science begins with the insight of a few scientists and how it develops by efforts of numerous independent scientists, in contrast to a policy-driven scientific project, such as the Human Genome Project, with goals clearly set at its inception and with work performed by a huge collaboration throughout the world. As more zinc finger proteins were discovered, several subfamilies, such as C2C2, CCHC, CCCH, LIM, RING, TAZ, and FYVE emerged, increasing our understanding of zinc fingers. The knowledge was overwhelming. Moreover, scientists began defining the term "zinc finger" differently and using various names for identical zinc fingers. These complications may explain why no single comprehensive resource of zinc finger proteins was available before this publication.

The Functional Nucleus

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Publisher : Springer
ISBN 13 : 3319388827
Total Pages : 501 pages
Book Rating : 4.3/5 (193 download)

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Book Synopsis The Functional Nucleus by : David P. Bazett-Jones

Download or read book The Functional Nucleus written by David P. Bazett-Jones and published by Springer. This book was released on 2016-10-17 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gives an in-depth overview on nuclear structure and function. It clearly shows that the epigenome and the three-dimensional organization of the nucleus are not independent properties. The intimate relationship between the location and the epigenetic modifications of gene loci is highlighted. Finally, it shows that the complex three-dimensional organization of the nucleus is not just of academic interest: The structure, composition and function of virtually all of the sub-nuclear compartments identified so far can be implicated to a list of human genetic diseases. Hence, a detailed elucidation of how these domains are assembled and function will provide new opportunities for therapeutic intervention in clinical practice.

The Flight of Ikaros

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Author :
Publisher : Penguin Group
ISBN 13 :
Total Pages : 194 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis The Flight of Ikaros by : Kevin Andrews

Download or read book The Flight of Ikaros written by Kevin Andrews and published by Penguin Group. This book was released on 1984 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: "On a chance commission to study medieval fortresses, Kevin Andrews found himself travelling, in the late forties, through Greece in the turmoil of a bloody civil war. His ... book is neither about fortresses nor about politics. Instead it reads like a novel and provides perhaps the first, certainly the most vivid, candid and memorable picture of modern Greek peasant life..."--Book jacket.

Tumor microenvironment in cancer hallmarks and therapeutics

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Publisher : Frontiers Media SA
ISBN 13 : 2832522815
Total Pages : 842 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Tumor microenvironment in cancer hallmarks and therapeutics by : Na Luo

Download or read book Tumor microenvironment in cancer hallmarks and therapeutics written by Na Luo and published by Frontiers Media SA. This book was released on 2023-06-05 with total page 842 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Analysis of the Ikaros Family of Proteins in Thymocyte Development

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Author :
Publisher :
ISBN 13 :
Total Pages : 368 pages
Book Rating : 4.:/5 ( download)

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Book Synopsis Analysis of the Ikaros Family of Proteins in Thymocyte Development by : Rupa Sridharan

Download or read book Analysis of the Ikaros Family of Proteins in Thymocyte Development written by Rupa Sridharan and published by . This book was released on 2006 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Molecular Biology of B Cells

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Publisher : Elsevier
ISBN 13 : 0123984904
Total Pages : 587 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Molecular Biology of B Cells by : Tasuku Honjo

Download or read book Molecular Biology of B Cells written by Tasuku Honjo and published by Elsevier. This book was released on 2014-10-09 with total page 587 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Biology of B Cells, Second Edition is a comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production. All of these developmental and stimulatory processes are described in molecular, immunological, and genetic terms to give a clear understanding of complex phenotypes. Molecular Biology of B Cells, Second Edition offers an integrated view of all aspects of B cells to produce a normal immune response as a constant, and the molecular basis of numerous diseases due to B cell abnormality. The new edition continues its success with updated research on microRNAs in B cell development and immunity, new developments in understanding lymphoma biology, and therapeutic targeting of B cells for clinical application. With updated research and continued comprehensive coverage of all aspects of B cell biology, Molecular Biology of B Cells, Second Edition is the definitive resource, vital for researchers across molecular biology, immunology and genetics. - Covers signaling mechanisms regulating B cell differentiation - Provides information on the development of therapeutics using monoclonal antibodies and clinical application of Ab - Contains studies on B cell tumors from various stages of B lymphocytes - Offers an integrated view of all aspects of B cells to produce a normal immune response

Characterization of Transcription Factor LyF-1/Ikaros

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Author :
Publisher :
ISBN 13 :
Total Pages : 382 pages
Book Rating : 4.:/5 ( download)

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Book Synopsis Characterization of Transcription Factor LyF-1/Ikaros by : Kyungmin Benjamin Hahm

Download or read book Characterization of Transcription Factor LyF-1/Ikaros written by Kyungmin Benjamin Hahm and published by . This book was released on 1997 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Ikaros, the Hellenistic Settlements

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Author :
Publisher : Jutland Archaeological Society
ISBN 13 :
Total Pages : 130 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Ikaros, the Hellenistic Settlements by : Hans Erik Mathiesen

Download or read book Ikaros, the Hellenistic Settlements written by Hans Erik Mathiesen and published by Jutland Archaeological Society. This book was released on 1982 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: Failaka/Ikaros -- The Hellenistic Settlements, Volume 3 - Danish Archaeological Investigations in Kuwait -- The Sacred Enclosure in the Early Hellenistic Period

Ikaros, the Hellenistic Settlements

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Author :
Publisher :
ISBN 13 : 9788788415025
Total Pages : 152 pages
Book Rating : 4.4/5 (15 download)

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Book Synopsis Ikaros, the Hellenistic Settlements by : Lise Hannestad

Download or read book Ikaros, the Hellenistic Settlements written by Lise Hannestad and published by . This book was released on 1983 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Ikaros

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Author :
Publisher : Wordtech Communications
ISBN 13 : 9781932339338
Total Pages : 100 pages
Book Rating : 4.3/5 (393 download)

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Book Synopsis Ikaros by : Constantine Contogenis

Download or read book Ikaros written by Constantine Contogenis and published by Wordtech Communications. This book was released on 2004 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Ikaros--the Hellenistic Settlements: no. 1. The Hellenistic pottery from Failaka : with a survey of Hellenistic pottery in the Near East

Download Ikaros--the Hellenistic Settlements: no. 1. The Hellenistic pottery from Failaka : with a survey of Hellenistic pottery in the Near East PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : 136 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Ikaros--the Hellenistic Settlements: no. 1. The Hellenistic pottery from Failaka : with a survey of Hellenistic pottery in the Near East by : Hans Erik Mathiesen

Download or read book Ikaros--the Hellenistic Settlements: no. 1. The Hellenistic pottery from Failaka : with a survey of Hellenistic pottery in the Near East written by Hans Erik Mathiesen and published by . This book was released on 1983 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt: