I. The Design, Development and Application of New Reactions: Total Synthesis of (+)-aphanamol I and Transition Metal-catalyzed Multicomponent Reactions II. Synthesis of (-)-laulimalide and Analogues

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ISBN 13 :
Total Pages : 844 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis I. The Design, Development and Application of New Reactions: Total Synthesis of (+)-aphanamol I and Transition Metal-catalyzed Multicomponent Reactions II. Synthesis of (-)-laulimalide and Analogues by : Lei Zhang

Download or read book I. The Design, Development and Application of New Reactions: Total Synthesis of (+)-aphanamol I and Transition Metal-catalyzed Multicomponent Reactions II. Synthesis of (-)-laulimalide and Analogues written by Lei Zhang and published by . This book was released on 2002 with total page 844 pages. Available in PDF, EPUB and Kindle. Book excerpt:

American Doctoral Dissertations

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ISBN 13 :
Total Pages : 776 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis American Doctoral Dissertations by :

Download or read book American Doctoral Dissertations written by and published by . This book was released on 2002 with total page 776 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Multicomponent reactions, metal-catalyzed tandem reactions, and total synthesis: development and applications in drug discovery

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ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (911 download)

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Book Synopsis Multicomponent reactions, metal-catalyzed tandem reactions, and total synthesis: development and applications in drug discovery by :

Download or read book Multicomponent reactions, metal-catalyzed tandem reactions, and total synthesis: development and applications in drug discovery written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Multicomponent Reactions, Metal-catalyzed Tandem Reactions, and Total Synthesis

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ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (914 download)

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Book Synopsis Multicomponent Reactions, Metal-catalyzed Tandem Reactions, and Total Synthesis by : Mette Terp Petersen

Download or read book Multicomponent Reactions, Metal-catalyzed Tandem Reactions, and Total Synthesis written by Mette Terp Petersen and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Applications of Transition Metal Catalysis in Drug Discovery and Development

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Publisher : John Wiley & Sons
ISBN 13 : 0470631325
Total Pages : 386 pages
Book Rating : 4.4/5 (76 download)

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Book Synopsis Applications of Transition Metal Catalysis in Drug Discovery and Development by : Matthew L. Crawley

Download or read book Applications of Transition Metal Catalysis in Drug Discovery and Development written by Matthew L. Crawley and published by John Wiley & Sons. This book was released on 2012-07-03 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the drug discovery and development applications of transition metal catalyzed processes, which can efficiently create preclinical and clinical drug candidates as well as marketed drugs. The authors pay particular attention to the challenges of transitioning academically-developed reactions into scalable industrial processes. Additionally, the book lays the groundwork for how continued development of transition metal catalyzed processes can deliver new drug candidates. This work provides a unique perspective on the applications of transition metal catalysis in drug discovery and development – it is a guide, a historical prospective, a practical compendium, and a source of future direction for the field.

Application of Transition Metal Catalysts in Organic Synthesis

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Publisher : Springer Science & Business Media
ISBN 13 : 3642603289
Total Pages : 349 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Application of Transition Metal Catalysts in Organic Synthesis by : L. Brandsma

Download or read book Application of Transition Metal Catalysts in Organic Synthesis written by L. Brandsma and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: Homogeneous catalysis is an important strategy for the synthesis of high-valued chemicals. L. Brandsma has carefully selected and checked the experimental procedures illustrating the catalytic use of copper, nickel, and palladium compounds in organic synthesis. All procedures are on a preparative scale, make economic use of solvents and catalysts, avoid toxic substances and have high yields.

Strategic Applications of Named Reactions in Organic Synthesis

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Publisher : Elsevier
ISBN 13 : 0080575412
Total Pages : 808 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Strategic Applications of Named Reactions in Organic Synthesis by : Laszlo Kurti

Download or read book Strategic Applications of Named Reactions in Organic Synthesis written by Laszlo Kurti and published by Elsevier. This book was released on 2005-04-29 with total page 808 pages. Available in PDF, EPUB and Kindle. Book excerpt: Kurti and Czako have produced an indispensable tool for specialists and non-specialists in organic chemistry. This innovative reference work includes 250 organic reactions and their strategic use in the synthesis of complex natural and unnatural products. Reactions are thoroughly discussed in a convenient, two-page layout--using full color. Its comprehensive coverage, superb organization, quality of presentation, and wealth of references, make this a necessity for every organic chemist. - The first reference work on named reactions to present colored schemes for easier understanding - 250 frequently used named reactions are presented in a convenient two-page layout with numerous examples - An opening list of abbreviations includes both structures and chemical names - Contains more than 10,000 references grouped by seminal papers, reviews, modifications, and theoretical works - Appendices list reactions in order of discovery, group by contemporary usage, and provide additional study tools - Extensive index quickly locates information using words found in text and drawings

Transition Metal Reagents and Catalysts

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Publisher : John Wiley & Sons
ISBN 13 : 9780471560272
Total Pages : 500 pages
Book Rating : 4.5/5 (62 download)

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Book Synopsis Transition Metal Reagents and Catalysts by : Jiro Tsuji

Download or read book Transition Metal Reagents and Catalysts written by Jiro Tsuji and published by John Wiley & Sons. This book was released on 2002-08-16 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: Im Laufe der vergangenen 35 Jahre wurden unzahlige Synthesewege entwickelt, bei denen Ubergangsmetallkomplexe entweder als Reagenzien oder als Katalysatoren fungieren. Dieses Buch bietet besonders denjenigen Synthesechemikern interessante und moderne Einblicke, die bisher noch nicht mit den vielfaltigen Moglichkeiten der Organometallchemie mit Ubergangsmetallen vertraut sind. Zu wichtigen ubergangsmetallkatalysierten Reaktionen werden Anwendungsbeispiele diskutiert. (01/00)

Development of New Transition Metal Catalyzed C-C Bond Forming Reactions and Their Application Toward Natural Product Synthesis

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ISBN 13 :
Total Pages : 670 pages
Book Rating : 4.:/5 (774 download)

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Book Synopsis Development of New Transition Metal Catalyzed C-C Bond Forming Reactions and Their Application Toward Natural Product Synthesis by : Abbas Hassan

Download or read book Development of New Transition Metal Catalyzed C-C Bond Forming Reactions and Their Application Toward Natural Product Synthesis written by Abbas Hassan and published by . This book was released on 2011 with total page 670 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Michael J. Krische research group we are developing new transition metal catalyzed Carbon-Carbon (C-C) forming reactions focusing on atom economy and byproduct free, environmental friendly approaches. We have developed a broad family of C-C bond forming hydrogenations with relative and absolute stereocontrol which provide an alternative to stoichiometric organometallic reagents in certain carbonyl and imine additions. Inspiring from the group work my goal was to develop new reactions, extend the scope of our group chemistry and their application towards synthesis of biologically active natural products. I have been part of enantioselective Rh catalyzed Aldol reaction of vinyl ketones to different aldehydes. Also, we have found that iridium catalyzed transfer hydrogenation of allylic acetates in the presence of aldehydes or alcohols results in highly enantioselective carbonyl allylation under the conditions of transfer hydrogenative. Based on this reactivity a concise enantio- and diastereoselective synthesis of 1,3-polyols was achieved via iterative chain elongation and bidirectional iterative asymmetric allylation was performed, which enables the rapid assembly of 1,3-polyol substructures with exceptional levels of stereocontrol. The utility of this approach stems from the ability to avoid the use of chirally modified allylmetal reagents, which require multistep preparation, and the ability to perform chain elongation directly from the alcohol oxidation level. This approach was utilized for the total synthesis of (+)-Roxaticin from 1,3-propanediol in 20 longest linear steps and a total number of 29 manipulations. Further, advancements were made in iridium catalyzed C-C bond formation under transfer hydrogenation. While methallyl acetate does not serve as an efficient allyl donor, the use of more reactive leaving group in methallyl chloride compensate for the shorter lifetime of the more highly substituted olefin [pi]-complex. Based on this insight into the requirements of the catalytic process, highly enantioselective Grignard-Nozaki-Hiyama methallylation is achieved from the alcohol or aldehyde oxidation levels. Also, a catalytic method for enantioselective vinylogous Reformatsky- type aldol addition was developed in which asymmetric carbonyl addition occurs with equal facility from the alcohol or aldehyde oxidation level. Good to excellent levels of regioselectivity and uniformly high levels of enantioselectivity were observed across a range of alcohols and aldehydes.

Handbook of Transition Metal Polymerization Catalysts

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Publisher : John Wiley & Sons
ISBN 13 : 1119242134
Total Pages : 696 pages
Book Rating : 4.1/5 (192 download)

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Book Synopsis Handbook of Transition Metal Polymerization Catalysts by : Ray Hoff

Download or read book Handbook of Transition Metal Polymerization Catalysts written by Ray Hoff and published by John Wiley & Sons. This book was released on 2018-05-08 with total page 696 pages. Available in PDF, EPUB and Kindle. Book excerpt: Including recent advances and historically important catalysts, this book overviews methods for developing and applying polymerization catalysts – dealing with polymerization catalysts that afford commercially acceptable high yields of polymer with respect to catalyst mass or productivity. • Contains the valuable data needed to reproduce syntheses or use the catalyst for new applications • Offers a guide to the design and synthesis of catalysts, and their applications in synthesis of polymers • Includes the information essential for choosing the appropriate reactions to maximize yield of polymer synthesized • Presents new chapters on vanadium catalysts, Ziegler catalysts, laboratory homopolymerization, and copolymerization

Copper-Catalyzed Multi-Component Reactions

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Publisher : Springer Science & Business Media
ISBN 13 : 3642154735
Total Pages : 110 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Copper-Catalyzed Multi-Component Reactions by : Yusuke Ohta

Download or read book Copper-Catalyzed Multi-Component Reactions written by Yusuke Ohta and published by Springer Science & Business Media. This book was released on 2011-01-20 with total page 110 pages. Available in PDF, EPUB and Kindle. Book excerpt: A copper-catalyzed direct synthesis of 2-(aminomethyl)indoles by catalytic domino reaction including multi-component coupling was developed, and is the first example of a three-component indole formation without producing salts as a byproduct. Based on this reaction, a copper-catalyzed synthesis of 3-(aminomethyl)isoquinoline was accomplished which represents an unprecedented isoquinoline synthesis through a four-component coupling reaction. Following these results, extensive application studies using one-pot palladium-, acid-, or base-promoted cyclization revealed that indole- or isoquinoline-fused polycyclic compounds can be readily synthesized through multi-component reactions. As the concept of Green Chemistry becomes ever more important, these findings may provide efficient and atom-economical approaches to the diversity-oriented synthesis of bioactive compounds containing a complex structure. This could lead to development of promising drug leads with structural complexity. The work of this thesis will go on to inspire the synthetic research of many readers.

Design, Discovery, and Development of Novel Metal-catalyzed Reactions and Their Use in Synthesis

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ISBN 13 :
Total Pages : 406 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Design, Discovery, and Development of Novel Metal-catalyzed Reactions and Their Use in Synthesis by : Mitchell Peter Croatt

Download or read book Design, Discovery, and Development of Novel Metal-catalyzed Reactions and Their Use in Synthesis written by Mitchell Peter Croatt and published by . This book was released on 2007 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Stereocontrolled Palladium(0) Catalyzed Allylic Alkylations in the Total Synthesis of (+)-valienamine

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ISBN 13 :
Total Pages : 610 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Stereocontrolled Palladium(0) Catalyzed Allylic Alkylations in the Total Synthesis of (+)-valienamine by : Louis S. Chupak

Download or read book Stereocontrolled Palladium(0) Catalyzed Allylic Alkylations in the Total Synthesis of (+)-valienamine written by Louis S. Chupak and published by . This book was released on 1997 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Multicomponent Reactions

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ISBN 13 : 9781118863992
Total Pages : pages
Book Rating : 4.8/5 (639 download)

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Book Synopsis Multicomponent Reactions by : Raquel P. Herrera

Download or read book Multicomponent Reactions written by Raquel P. Herrera and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Multicomponent Reactions

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ISBN 13 :
Total Pages : 507 pages
Book Rating : 4.:/5 (914 download)

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Book Synopsis Multicomponent Reactions by :

Download or read book Multicomponent Reactions written by and published by . This book was released on 2015 with total page 507 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Nanocatalysis

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Publisher : John Wiley & Sons
ISBN 13 : 111814886X
Total Pages : 755 pages
Book Rating : 4.1/5 (181 download)

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Book Synopsis Nanocatalysis by : Vivek Polshettiwar

Download or read book Nanocatalysis written by Vivek Polshettiwar and published by John Wiley & Sons. This book was released on 2013-09-30 with total page 755 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exhibiting both homogeneous and heterogeneous catalytic properties, nanocatalysts allow for rapid and selective chemical transformations, with the benefits of excellent product yield and ease of catalyst separation and recovery. This book reviews the catalytic performance and the synthesis and characterization of nanocatalysts, examining the current state of the art and pointing the way towards new avenues of research. Moreover, the authors discuss new and emerging applications of nanocatalysts and nanocatalysis, from pharmaceuticals to fine chemicals to renewable energy to biotransformations. Nanocatalysis features contributions from leading research groups around the world. These contributions reflect a thorough review of the current literature as well as the authors’ first-hand experience designing and synthesizing nanocatalysts and developing new applications for them. The book’s nineteen chapters offer a broad perspective, covering: Nanocatalysis for carbon-carbon and carbon-heteroatom coupling reactions Nanocatalysis for various organic transformations in fine chemical synthesis Nanocatalysis for oxidation, hydrogenation, and other related reactions Nanomaterial-based photocatalysis and biocatalysis Nanocatalysts to produce non-conventional energy such as hydrogen and biofuels Nanocatalysts and nano-biocatalysts in the chemical industry Readers will also learn about the latest spectroscopic and microscopy tools used in advanced characterization methods that shed new light on nanocatalysts and nanocatalysis. Moreover, the authors offer expert advice to help readers develop strategies to improve catalytic performance. Summarizing and reviewing all the most important advances in nanocatalysis over the last two decades, this book explains the many advantages of nanocatalysts over conventional homogeneous and heterogeneous catalysts, providing the information and guidance needed for designing green, sustainable catalytic processes.

Design and Development of New Transition Metal-catalyzed Two-and Three-component Cycloaddition Reactions

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ISBN 13 :
Total Pages : 570 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Design and Development of New Transition Metal-catalyzed Two-and Three-component Cycloaddition Reactions by : Nicole Marie Deschamps

Download or read book Design and Development of New Transition Metal-catalyzed Two-and Three-component Cycloaddition Reactions written by Nicole Marie Deschamps and published by . This book was released on 2006 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: