Hysteresis Phenomena in Biology

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Publisher : Springer Science & Business Media
ISBN 13 : 3642382185
Total Pages : 51 pages
Book Rating : 4.6/5 (423 download)

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Book Synopsis Hysteresis Phenomena in Biology by : Hamid Reza Noori

Download or read book Hysteresis Phenomena in Biology written by Hamid Reza Noori and published by Springer Science & Business Media. This book was released on 2013-11-27 with total page 51 pages. Available in PDF, EPUB and Kindle. Book excerpt: The occurrence of hysteresis phenomena has been traditionally associated with mechanical and magnetic properties of materials. However, recent studies on the dynamics of biological processes suggest switch-like behavior that could be described by mathematical models of hysteresis. This book presents the milestones and perspectives of biological hysteresis and provides a comprehensive and application-oriented introduction to this subject. The target audience primarily comprises researchers but the book may also be beneficial for graduate students.

Noise-Driven Phenomena in Hysteretic Systems

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Publisher : Springer Science & Business Media
ISBN 13 : 1461413745
Total Pages : 240 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Noise-Driven Phenomena in Hysteretic Systems by : Mihai Dimian

Download or read book Noise-Driven Phenomena in Hysteretic Systems written by Mihai Dimian and published by Springer Science & Business Media. This book was released on 2013-11-04 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Noise-Driven Phenomena in Hysteretic Systems provides a general approach to nonlinear systems with hysteresis driven by noisy inputs, which leads to a unitary framework for the analysis of various stochastic aspects of hysteresis. This book includes integral, differential and algebraic models that are used to describe scalar and vector hysteretic nonlinearities originating from various areas of science and engineering. The universality of the authors approach is also reflected by the diversity of the models used to portray the input noise, from the classical Gaussian white noise to its impulsive forms, often encountered in economics and biological systems, and pink noise, ubiquitous in multi-stable electronic systems. The book is accompanied by HysterSoft© - a robust simulation environment designed to perform complex hysteresis modeling – that can be used by the reader to reproduce many of the results presented in the book as well as to research both disruptive and constructive effects of noise in hysteretic systems.

Systems with Hysteresis

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Publisher : Springer Science & Business Media
ISBN 13 : 3642613020
Total Pages : 429 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Systems with Hysteresis by : Mark A. Krasnosel'skii

Download or read book Systems with Hysteresis written by Mark A. Krasnosel'skii and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hysteresis phenomena are common in numerous physical, mechanical, ecological and biological systems. They reflect memory effects and process irreversibility. The use of hysteresis operators (hysterons) offers an approach to macroscopic modelling of the dynamics of phase transitions and rheological systems. The applications cover processes in electromagnetism, elastoplasticity and population dynamics in particular. Hysterons are also typical elements of control systems where they represent thermostats and other discontinuous controllers with memory. The book offers the first systematic mathematical treatment of hysteresis nonlinearities. Construction procedures are set up for hysterons in various function spaces, in continuous and discontinuous cases. A general theory of variable hysterons is developed, including identification and stability questions. Both deterministic and non-deterministic hysterons are considered, with applications to the study of feedback systems. Many of the results presented - mostly obtained by the authors and their scientific group - have not been published before. The book is essentially self contained and is addressed both to researchers and advanced students.

Nonlinear Phenomena in Physics and Biology

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Publisher : Springer Science & Business Media
ISBN 13 : 146844106X
Total Pages : 609 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Nonlinear Phenomena in Physics and Biology by : Richard H. Enns

Download or read book Nonlinear Phenomena in Physics and Biology written by Richard H. Enns and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 609 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Advanced Study Institute (ASI) on Nonlinear Phenomena-in Physics and Biology was held at the Banff Centre, Banff, Alberta, Canada, from 17 - 29 August, 1980. The Institute was made possible through funding by the North Atlantic Treaty Organization (who sup plied the major portion of the financial aid), the National Research and Engineering Council of Canada, and Simon Fraser University. The availability of the Banff Centre was made possible through the co sponsorship (with NATO) of the ASI by the Canadian Association of Physicists. 12 invited lecturers and 82 other participants attended the Institute. Except for two lectures on nonlinear waves by Norman Zabusky, which were omitted because it was felt that they already had been exhaustively treated in the available literature, this volume contains the entire text of the invited lectures. In addition, short reports on some of the contributed talks have also been included. The rationale for the ASI and this resulting volume was that many of the hardest problems and most interesting phenomena being studied by scientists today ar.e nonlinear in nature. The nonlinear models involved often span several different disciplines, °a simple example being the Volterra-type model in population dynamics which has its analogue in nonlinear optics and plasma physics (the 3-wave problem), in the discussion of the social behavior of animals, and in biological competition and selection at the molecular level.

Hysteresis

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Publisher : Nova Science Publishers
ISBN 13 : 9781633213364
Total Pages : 0 pages
Book Rating : 4.2/5 (133 download)

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Book Synopsis Hysteresis by : José Carlos Dias

Download or read book Hysteresis written by José Carlos Dias and published by Nova Science Publishers. This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of complex hysteresis problems has become increasingly important in recent years, since the hysteresis phenomenon affects significantly the decisions that have to be rendered in a wide range of real-world practical applications. For example, the so-called hysteresis effects may influence substantially some fields not directly related to the natural sciences such as finance, economy, or fiscal policy. In addition, such phenomenon is also typically present in many engineering and physics applications of interest such as in magnetism, spin-valve technology, semiconductors, surface physics, aeronautical and civil engineering aerodynamics, complex battery systems, biology, etc. This book focuses on the most recent attempts for modeling a diverse variety of complex hysteresis problems faced in economics, engineering, and physics. The chapters of this book provide a self-contained, rigorous, and clear treatment of the different types and sources of hysteresis under a large spectrum of applications. The book also highlights how stochastic control and other mathematical tools as well as econometric techniques can be applied for analyzing the complex properties of hysteresis problems. This authoritative book is a definitive guide on how to understand the newest designs for modeling hysteresis in highly complex systems and thus it will be an essential reading for graduate students and researchers in economics, engineering, and physics.

Electricity and Magnetism in Biology and Medicine

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Publisher : Springer Science & Business Media
ISBN 13 : 1461548675
Total Pages : 961 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Electricity and Magnetism in Biology and Medicine by : Ferdinando Bersani

Download or read book Electricity and Magnetism in Biology and Medicine written by Ferdinando Bersani and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 961 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, a selection of the papers presented at the 2nd World Congress for Electricity and Magnetism, provides state-of-the-art information on applications of electricity and electromagnetic fields on living organisms, especially man.

The Biology of Acinetobacter

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Publisher : Springer Science & Business Media
ISBN 13 : 1489935533
Total Pages : 450 pages
Book Rating : 4.4/5 (899 download)

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Book Synopsis The Biology of Acinetobacter by : K.J. Towner

Download or read book The Biology of Acinetobacter written by K.J. Towner and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 1st International Workshop on Acinetobacter was held on 6th September, 1986, in Manchester, England, in association with the 14th International Congress of Microbiology. That occasion was so well attended and productive that there were soon discussions about how, when and where the next meeting should be held. This time, however, there was sufficient confidence to think of a more substantial meeting and to plan for the proceedings to be published. It emerged that there was wide agreement that the time was ripe to take stock of the entire biology of Acinetobacter: its occurrence and taxonomy; its molecular biology, biochemistry and physiology; its clinical importance and its industrial and commercial applications. The 2nd International Workshop on Acinetobacter took place from 6th to 7th September, 1990, at the Institut Pasteur, Paris, and was sponsored by the Federation of European Microbiological Societies. There were about 100 participants from 19 countries. The backbone of the meeting consisted of 23 plenary lectures. There were 28 posters and the meeting closed with a general discussion which went on long after the official finishing time despite all the counter-attractions of a sunny Parisian Friday afternoon. Indeed discussions continued while cruising along the Seine and while dining at the top of the Tour Montparnasse. However, the vitality and usefulness of even the most successful meeting is difficult to transmit by the printed word.

Metal-Organic and Organic Molecular Magnets

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Publisher : Royal Society of Chemistry
ISBN 13 : 1847551394
Total Pages : 333 pages
Book Rating : 4.8/5 (475 download)

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Book Synopsis Metal-Organic and Organic Molecular Magnets by : Peter Day

Download or read book Metal-Organic and Organic Molecular Magnets written by Peter Day and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traditionally, magnetic materials have been metals or, if inorganic compounds such as oxides, of continuous lattice type. However, in recent years chemists have synthesized increasing numbers of crystalline solids based on molecular building blocks in the form of coordination and organometallic complexes or purely organic molecules, which exhibit spontaneous magnetization. In striking contrast to conventional magnets, these materials are made from solutions close to room temperature rather than by metallurgical or ceramic methods. This book, which originates from contributions to a Discussion Meeting of The Royal Society of London, brings together many of the leading international practitioners in the field, who survey their own recent work and place it in the context of the wider fields of magnetism and supramolecular chemistry. All aspects of molecular-based magnets are addressed, including synthesis, structure-property relations and physical properties. Contents include details of the characterization of the first purely organic ferromagnet, the synthesis of high coercivity materials and a unique description of new materials with Curie temperatures well above ambient. A coherent survey of this rapidly developing field for the more general reader, Metal-Organic and Organic Molecular Magnets will also be welcomed by researchers and lecturers in materials science and inorganic or solid state chemistry.

Fluid Dynamics in Biology

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Publisher : American Mathematical Soc.
ISBN 13 : 0821851489
Total Pages : 602 pages
Book Rating : 4.8/5 (218 download)

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Book Synopsis Fluid Dynamics in Biology by : Angela Y. Cheer

Download or read book Fluid Dynamics in Biology written by Angela Y. Cheer and published by American Mathematical Soc.. This book was released on 1993 with total page 602 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains nearly all the papers presented at the AMS-IMS-SIAM Joint Summer Research Conference on Biofluiddynamics, held in July 1991, at the University of Washington, Seattle. The lead paper, by Sir James Lighthill, presents a comprehensive review of external flows in biology. The other papers on external and internal flows illuminate developments in the protean field of biofluiddynamics from diverse viewpoints, reflecting the field's multidisciplinary nature. For this reason, the work should be useful to mathematicians, biologists, engineers, physiologists, cardiologists and oceanographers alike. The papers highlight a number of problems that have remained largely unexplored due to the difficulty of addressing biological flow motions, which are often governed by large systems of nonlinear differential equations and involve complex geometries. However, recent advances in computational fluid dynamics have expanded opportunities to solve such problems. These developments have increased interest in areas such as the mechanisms of blood and air flow in humans, the dynamic ecology of the oceans, animal swimming and flight, to name a few.

Introduction to Systems Biology

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Publisher : Open Book Publishers
ISBN 13 : 1800644124
Total Pages : 172 pages
Book Rating : 4.8/5 (6 download)

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Book Synopsis Introduction to Systems Biology by : Thomas Sauter

Download or read book Introduction to Systems Biology written by Thomas Sauter and published by Open Book Publishers. This book was released on 2023-03-09 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an introduction to the language of systems biology, which is spoken among many disciplines, from biology to engineering. Authors Thomas Sauter and Marco Albrecht draw on a multidisciplinary background and evidence-based learning to facilitate the understanding of biochemical networks, metabolic modeling and system dynamics. Their pedagogic approach briefly highlights core ideas of concepts in a broader interdisciplinary framework to guide a more effective deep dive thereafter. The learning journey starts with the purity of mathematical concepts, reveals its power to connect biological entities in structure and time, and finally introduces physics concepts to tightly align abstraction with reality. This workbook is all about self-paced learning, supports the flipped-classroom concept, and kick-starts with scientific evidence on studying. Each chapter comes with links to external YouTube videos, learning checklists, and Integrated real-world examples to gain confidence in thinking across scientific perspectives. The result is an integrated approach that opens a line of communication between theory and application, enabling readers to actively learn as they read. This overview of capturing and analyzing the behavior of biological systems will interest adherers of systems biology and network analysis, as well as related fields such as bioinformatics, biology, cybernetics, and data science.

An Introduction to Mathematical Modeling in Physiology, Cell Biology, and Immunology

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Publisher : American Mathematical Soc.
ISBN 13 : 0821828169
Total Pages : 194 pages
Book Rating : 4.8/5 (218 download)

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Book Synopsis An Introduction to Mathematical Modeling in Physiology, Cell Biology, and Immunology by : James Sneyd

Download or read book An Introduction to Mathematical Modeling in Physiology, Cell Biology, and Immunology written by James Sneyd and published by American Mathematical Soc.. This book was released on 2002 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: In many respects, biology is the new frontier for applied mathematicians. This book demonstrates the important role mathematics plays in the study of some biological problems. It introduces mathematicians to the biological sciences and provides enough mathematics for bioscientists to appreciate the utility of the modelling approach. The book presents a number of diverse topics, such as neurophysiology, cell biology, immunology, and human genetics. It examines how research is done, what mathematics is used, what the outstanding questions are, and how to enter the field. Also given is a brief historical survey of each topic, putting current research into perspective. The book is suitable for mathematicians and biologists interested in mathematical methods in biology.

Hysteresis And Neural Memory

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Publisher : World Scientific
ISBN 13 : 9811209529
Total Pages : 292 pages
Book Rating : 4.8/5 (112 download)

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Book Synopsis Hysteresis And Neural Memory by : Mayergoyz Isaak D

Download or read book Hysteresis And Neural Memory written by Mayergoyz Isaak D and published by World Scientific. This book was released on 2019-08-20 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a concise and rigorous exposition of Preisach hysteresis models and their applications to the modeling of neural memory. It demonstrates that memory of Preisach hysteresis models mimics such properties as: selective nature of neural memories extracted from sensory inputs, distributed nature of neural memories and their engrams, neural memory formation as an emerging property of sparse connectivity, neural memory stability with respect to protein turnover, neural memory storage plasticity and neural memory recalls and their effect on storage.The text is designed to be accessible and appealing to a broad audience of neuroscientists, biologists, bioengineers, electrical engineers, applied mathematicians and physicists interested in neural memory and its molecular basis.

Biological Processes in Living Systems

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Publisher : Routledge
ISBN 13 : 1351297155
Total Pages : 312 pages
Book Rating : 4.3/5 (512 download)

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Book Synopsis Biological Processes in Living Systems by : C. H. Waddington

Download or read book Biological Processes in Living Systems written by C. H. Waddington and published by Routledge. This book was released on 2017-09-08 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological Processes in Living Systems is the fourth and final volume of the Toward a Theoretical Biology series. It contains essays that deal in detail with particular biological processes: morphogenesis of pattern, the development of neuronal networks, evolutionary processes, and others. The main thrust of this volume brings relevance to the general underlying nature of living systems. Faced with trying to understand how the complexity of molecular microstates leads to the relative simplicity of phenome structures, Waddington-on behalf of his colleagues-stresses on the structure of language as a paradigm for a theory of general biology. This is language in an imperative mood: a set of symbols, organized by some form of generative grammar, making possible the conveyance of commands for action to produce effects on the surroundings of the emitting and the receiving entities. "Biology," he writes, "is concerned with algorithm and program." Among the contributions in this volume are: "The Riemann-Hugoniot Catastrophe and van der Waals Equation," David H. Fowler; "Differential Equations for the Heartbeat and Nerve Impulse," E. Christopher Zeeman; "Structuralism and Biology," Rene Thom; "The Concept of Positional Information and Pattern Formation," Lewis Wolpert; "Pattern Formation in Fibroblast Cultures," Tom Elsdale; "Form and Information," C. H. Waddington; "Organizational Principles for Theoretical Neurophysiology," Michael A. Arbib; "Stochastic Models of Neuroelectric Activity," Jack D. Cowan. Biological Processes in Living Systems is a pioneering volume by recognized leaders in an ever-growing field.

Unsolved Problems of Noise and Fluctuations

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Publisher : Springer Science & Business Media
ISBN 13 : 9780735401273
Total Pages : 644 pages
Book Rating : 4.4/5 (12 download)

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Book Synopsis Unsolved Problems of Noise and Fluctuations by : Sergey M. Bezrukov

Download or read book Unsolved Problems of Noise and Fluctuations written by Sergey M. Bezrukov and published by Springer Science & Business Media. This book was released on 2003-06-02 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt: All papers in this proceedings volume were peer reviewed. The purview of this third conference was shifted toward biology and medicine. Among the topics covered were: the constructive role of noise in the central nervous system, neuronal networks, and sensory transduction (hearing in humans, photo- and electroreception in marine animals), encoding of information into nerve pulse trains, single molecules and noise (including single molecule detection and characterization by nanopores - molecular "Coulter counting"), concepts of noise in neurophysiology (randomness and order in brain and heart electrical activities under normal conditions and in pathology), the role of noise in genetic regulation and gene expression, biosensors, etc.

Homeostasis and Allostasis of Thyroid Function

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Publisher : Frontiers Media SA
ISBN 13 : 288945570X
Total Pages : 107 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Homeostasis and Allostasis of Thyroid Function by : Johannes W. Dietrich

Download or read book Homeostasis and Allostasis of Thyroid Function written by Johannes W. Dietrich and published by Frontiers Media SA. This book was released on 2018-08-29 with total page 107 pages. Available in PDF, EPUB and Kindle. Book excerpt: The discovery of the negative feedback of thyroid hormones on pituitary thyroid-stimulating hormone (TSH) secretion, a classical endocrine feedback control system, has shaped diagnosis and treatment of thyroid disease for the last decades. Based on this concept, a unique diagnostic category of subclinical thyroid disorders was introduced, being defined exclusively by an abnormal TSH response in the presence of thyroid hormone concentrations within the reference range. Although this approach was able to deliver a conceptually straightforward disease definition problems surfaced in clinical practice as neither the diagnostic reference range nor the appropriate threshold for initiating substitution treatment are universally agreed upon for subclinical thyroid disorders. The situation is further aggravated by the so-called syndrome T, which comprises a substantial but heterogeneous group of L-T4 treated patients with hypothyroidism with reduced quality of life despite “normal” TSH values. A limited understanding of the physiological relationships between TSH and thyroid hormones may be a main reason for clinical difficulties in dealing with the causes of syndrome T and tailoring substitution therapy for hypothyroid patients with subclinical thyroid disorders. Feedback regulation has recently been shown to be much more complex than previously assumed. The concept of homeostatic control has also been extended to include the lesser known but equally important allostatic thyroid regulation.The latter aims at adaptive homeostasis or stability through changing setpoints and modulating structural parameters of feedback control, as may be appropriate to adapt to a vast array of conditions spanning from fetal life, aging, pregnancy, exercise, starvation, obesity, psychiatric disorders to the severe non-thyroidal illness syndrome. A better understanding of homeostatic and allostatic mechanisms, which govern the behaviour of pituitary-thyroid feedback control, is on the horizon. This promises to improve the diagnostic utility of laboratory methods, laying the foundation for personalised methods to optimise dosage and modality of substitution therapy. The emerging new world of thyroid physiology is reflected on the side of clinical medicine in a new, relational paradigm for diagnosis and treatment. Considerable progress has been made in this respect in the following key areas: • the significance of complementary information processing structures within the feedback loop, in particular ultrashort feedback of TSH on its own secretion and the action of a TSH-T3 shunt unburdening the thyroid from T4 synthesis in imminent thyroid failure, • the unravelling of spatio-temporal dynamics of hormone concentrations ranging from ultradian to circannual rhythms and including hysteresis effects, • the emergence of “non-canonical” mechanisms of thyroid hormone signalling beyond transcriptional control of gene expression, • the physiological actions of thyronine metabolites, which have been previously regarded as biologically inactive, such as thyronamines and iodothyroacetates, • the characterisation of distinct patterns in the adaptive processes to stress and strain and their conclusive explanation through reactions to type 1 and type 2 allostatic load. This collective volume contains the contributions to the Research Topic “Homeostasis and Allostasis of Thyroid Function”, which was originally published by the journal Frontiers in Endocrinology. Authored by an international team of experts from three continents ,the book provides a comprehensive overview on thyroid control from recent research in basic, computational and clinical thyroidology. Many aspects addressed here can be expected to stimulate future research. A more comprehensive view and better integration of in-vitro, in-silico and in-vivo investigations will be invaluable in paving the way to this new world of thyroidology.

Ecohydrology & Hydrobiology

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Publisher :
ISBN 13 :
Total Pages : 116 pages
Book Rating : 4./5 ( download)

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Book Synopsis Ecohydrology & Hydrobiology by :

Download or read book Ecohydrology & Hydrobiology written by and published by . This book was released on 2005 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: The international journal Ecohydrology & Hydrobiology (E&H) has been created to promote the concept of Ecohydrology, which is defined as the study of the functional interrelations between hydrology and biota at the catchment scale. Ecohydrology extends from the molecular level to catchment-scale processes and is based on three principles: • framework (hydrological principle) - quantification and integration of hydrological and ecological processes at a basin scale; • target (ecological principle) - necessity of enhancing ecosystem absorbing capacity and ecosystem services; and • management tool (ecological engineering) – the use of ecosystem properties for regulation the interplay between hydrology and biota. The journal encourages the submission of manuscripts which adopt an integrative approach to aquatic sciences, explaining ecological and hydrological processes at a river-basin scale or propose practical applications of this knowledge. It will also consider papers in other hydrobiological fields. Especially welcome are papers on regulatory mechanism within biocenosis and the resistance and resilience of freshwater and costal zones ecosystems. There is no page charge for published papers. All submitted papers, written exclusively in English, should be original works, unpublished and not under consideration for publication elsewhere. All papers are peer-reviewed. The following types of papers are considered for publication in E&H: • original research papers • invited or submitted review papers, • short communications

Reproducibility in Biomedical Research

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Publisher : Elsevier
ISBN 13 : 0443138303
Total Pages : 464 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Reproducibility in Biomedical Research by : Erwin B. Montgomery Jr.

Download or read book Reproducibility in Biomedical Research written by Erwin B. Montgomery Jr. and published by Elsevier. This book was released on 2024-04-29 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reproducibility in Biomedical Research: Epistemological and Statistical Problems, 2nd Ed. explores the ideas and conundrums inherent in scientific research. Reproducibility is one of the biggest challenges in biomedical research. It affects not only the ability to replicate results, but the very trust in the findings. Since published in 2019, Reproducibility of Biomedical Research: Epistemological and Statistical Problems established itself as a solid ethical reference in the area, leading to significant reflection on biomedical research. The second edition addresses new challenges to reproducibility in biosciences, namely reproducibility of machine learning Artificial Intelligence (AI), reproducibility of translation from research to medical care, and the fundamental challenges to reproducibility. All current chapters will be expanded to cover advances in the topics previously addressed. Reproducibility in Biomedical Research: Epistemological and Statistical Problems, 2nd Ed. provides biomedical researchers with a framework to better understand the reproducibility challenges in the area. Newly introduced interactive exercises and updated case studies help students understand the fundamental concepts involved in the area. - Includes four new chapters and updates across the book, covering recent developments of issues affecting reproducibility in biomedical research - Covers reproducibility of results from machine learning AI algorithms - Presents new case studies to illustrate challenges in related fields - Includes a companion website with interactive exercises and summary tables