The Arctic Aeromedical Laboratory's Thyroid Function Study

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Author :
Publisher : National Academies Press
ISBN 13 : 0309175925
Total Pages : 116 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Arctic Aeromedical Laboratory's Thyroid Function Study by : National Research Council

Download or read book The Arctic Aeromedical Laboratory's Thyroid Function Study written by National Research Council and published by National Academies Press. This book was released on 1996-01-26 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the 1950s, with the Cold War looming, military planners sought to know more about how to keep fighting forces fit and capable in the harsh Alaskan environment. In 1956 and 1957, the U.S. Air Force's former Arctic Aeromedical Laboratory conducted a study of the role of the thyroid in human acclimatization to cold. To measure thyroid function under various conditions, the researchers administered a radioactive medical trace, Iodine-131, to Alaska Natives and white military personnel; based on the study results, the researchers determined that the thyroid did not play a significant role in human acclimatization to cold. When this study of thyroid function was revisited at a 1993 conference on the Cold War legacy in the Arctic, serious questions were raised about the appropriateness of the activityâ€"whether it posed risks to the people involved and whether the research had been conducted within the bounds of accepted guidelines for research using human participants. In particular, there was concern over the relatively large proportion of Alaska Natives used as subjects and whether they understood the nature of the study. This book evaluates the research in detail, looking at both the possible health effects of Iodine-131 administration in humans and the ethics of human subjects research. This book presents conclusions and recommendations and is a significant addition to the nation's current reevaluation of human radiation experiments conducted during the Cold War.

Human Experimentation and Research

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Publisher : Routledge
ISBN 13 : 1351772384
Total Pages : 1160 pages
Book Rating : 4.3/5 (517 download)

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Book Synopsis Human Experimentation and Research by : George F. Tomossy

Download or read book Human Experimentation and Research written by George F. Tomossy and published by Routledge. This book was released on 2017-07-12 with total page 1160 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title was first published in 2003: As new medical technologies and treatments develop with increasing momentum, the legal and ethical implications of research involving human participants are being called into question as never before. Human Experimentation and Research explores the philosophical foundations of research ethics, ongoing regulatory dilemmas, and future challenges raised by the rapid globalisation and corporatisation of the research endeavour. This volume brings together some of the most significant published essays in the field. The editors also provide an informative introduction, summarizing the area and the relevance of the articles chosen.

Experimentation with Human Beings

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Author :
Publisher : Russell Sage Foundation
ISBN 13 : 1610448340
Total Pages : 1210 pages
Book Rating : 4.6/5 (14 download)

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Book Synopsis Experimentation with Human Beings by : Jay Katz

Download or read book Experimentation with Human Beings written by Jay Katz and published by Russell Sage Foundation. This book was released on 1972-07-24 with total page 1210 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, increasing concern has been voiced about the nature and extent of human experimentation and its impact on the investigator, subject, science, and society. This casebook represents the first attempt to provide comprehensive materials for studying the human experimentation process. Through case studies from medicine, biology, psychology, sociology, and law—as well as evaluative materials from many other disciplines—Dr. Katz examines the problems raised by human experimentation from the vantage points of each of its major participants—investigator, subject, professions, and state. He analyzes what kinds of authority should be delegated to these participants in the formulation, administration, and review of the human experimentation process. Alternative proposals, from allowing investigators a completely free hand to imposing centralized governmental control, are examined from both theoretical and practical perspectives. The conceptual framework of Experimentation with Human Beings is designed to facilitate not only the analysis of such concepts as "harm," "benefit," and "informed consent," but also the exploration of the problems raised by man's quest for knowledge and mastery, his willingness to risk human life, and his readiness to delegate authority to professionals and rely on their judgment.

The Ethics and Politics of Human Experimentation

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Author :
Publisher : CUP Archive
ISBN 13 : 9780521416276
Total Pages : 340 pages
Book Rating : 4.4/5 (162 download)

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Book Synopsis The Ethics and Politics of Human Experimentation by : Paul Murray McNeill

Download or read book The Ethics and Politics of Human Experimentation written by Paul Murray McNeill and published by CUP Archive. This book was released on 1993-05-28 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: The author finds that these committees are predominantly influenced by members of research institutions and by the researchers themselves. Yet researchers, and their institutions, stand to gain considerable benefits from the experiments they conduct. Dr McNeill argues that committees of review, as they are presently constituted, cannot be relied on to ensure an equitable balance between the interests of researchers and the interests of the human subjects experimented on. He proposes a radically different rationale and model for committee review.

In the Name of Science

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Publisher : St. Martin's Press
ISBN 13 : 1429997931
Total Pages : 648 pages
Book Rating : 4.4/5 (299 download)

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Book Synopsis In the Name of Science by : Andrew Goliszek

Download or read book In the Name of Science written by Andrew Goliszek and published by St. Martin's Press. This book was released on 2003-11-15 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: Science, as Andrew Goliszek proves in this compendious, chilling, and eye-opening book, has always had its dark side. Behind the bright promise of life-saving vaccines and life-enhancing technologies lies the true cost of the efforts to develop them. Knowledge has a price; often that price has been human suffering. The ethical limits governing use of the human body in experimentation have been breached, redefined, and breached again---from the moment the first plague-ridden corpse was heaved over the fortifications of a besieged medieval city to the use of cutting-edge gene therapy today. Those limits are in constant need of redefinition, for the goals and the techniques have become both more refined and more secretive. The German and Japanese human experiments of the 1930s and 1940s horrified the world when they came to light. These barbaric exercises in pseudoscience grew out of assumptions of racial superiority. The subjects were deemed subhuman; ordinary guidelines could therefore be suspended. What has happened in the decades since World War II has differed only in degree. Explicitly or implicitly, any organization or government that undertakes or sponsors scientific research applies some measure of human worth. Experimentation rests upon an equation that balances suffering against gain, the good of the collective against the rights of the individual, and the risk of unknown consequences against the rewards of scientific discovery. Everything depends upon who makes that equation. The sobering and gripping accumulation of evidence in this book proves exactly what has been justified in the name of science. The science of "eugenics" justified enforced sterilization. The need to gain an upper hand in the Cold War justified CIA experiments involving mind control and drugs. The desperate race to control nuclear proliferation was used to justify radiation experiments whose effects are still being felt today. Chemical warfare, gene therapy, molecular medicine: These subjects dominate headlines and even direct our government's foreign policy, yet the whole truth about the experimentation behind them has never been made public. Though not a cheering book, In the Name of Science is a crucially important one, and it deserves a wide audience. A biologist by training, Goliszek presents each topic clearly and explains fully its significance and implications. Connecting the history of scientific experimentation through time with the topics that are likely to dominate the future, he has performed an invaluable service. No other book on the market provides the research included here, or presents it with such persuasive force.

Subjected to Science

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Publisher : JHU Press
ISBN 13 : 9780801857096
Total Pages : 226 pages
Book Rating : 4.8/5 (57 download)

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Book Synopsis Subjected to Science by : Susan E. Lederer

Download or read book Subjected to Science written by Susan E. Lederer and published by JHU Press. This book was released on 1997-11-07 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Susan Lederer provides the first full-length history of early biomedical research with human subjects. Lederer offers detailed accounts of experiments conducted on both healthy and unhealthy men, women, and children, during the period from 1890 to 1940, including yellow fever experiments, Udo Wile's "dental drill" experiments on insane patients, and Hideyo Noguchi's syphilis experiments.

The Belmont Report

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Publisher :
ISBN 13 :
Total Pages : 614 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis The Belmont Report by : United States. National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research

Download or read book The Belmont Report written by United States. National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research and published by . This book was released on 1978 with total page 614 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Mind Wars

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Publisher : Bellevue Literary Press
ISBN 13 : 1934137502
Total Pages : 224 pages
Book Rating : 4.9/5 (341 download)

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Book Synopsis Mind Wars by : Jonathan D. Moreno

Download or read book Mind Wars written by Jonathan D. Moreno and published by Bellevue Literary Press. This book was released on 2012-05-01 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: “One of the most important thinkers describes the literally mind-boggling possibilities that modern brain science could present for national security.” —LAWRENCE J. KORB, former US Assistant Secretary of Defense “Fascinating and frightening.” —Bulletin of the Atomic Scientists The first book of its kind, Mind Wars covers the ethical dilemmas and bizarre history of cutting-edge technology and neuroscience developed for military applications. As the author discusses the innovative Defense Advanced Research Projects Agency (DARPA) and the role of the intelligence community and countless university science departments in preparing the military and intelligence services for the twenty-first century, he also charts the future of national security. Fully updated and revised, this edition features new material on deep brain stimulation, neuro hormones, and enhanced interrogation. With in-depth discussions of “psyops” mind control experiments, drugs that erase both fear and the need to sleep, microchip brain implants and advanced prosthetics, supersoldiers and robot armies, Mind Wars may read like science fiction or the latest conspiracy thriller, but its subjects are very real and changing the course of modern warfare. Jonathan D. Moreno has been a senior staff member for three presidential advisory commissions and has served on a number of Pentagon advisory committees. He is an ethics professor at the University of Pennsylvania and the editor-in-chief of the Center for American Progress’ online magazine Science Progress.

Human Guinea Pigs

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (124 download)

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Book Synopsis Human Guinea Pigs by : M. H. Pappworth

Download or read book Human Guinea Pigs written by M. H. Pappworth and published by . This book was released on 1967 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Research on Human Subjects

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Publisher : Routledge
ISBN 13 : 135131842X
Total Pages : 263 pages
Book Rating : 4.3/5 (513 download)

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Book Synopsis Research on Human Subjects by : Bernard Barber

Download or read book Research on Human Subjects written by Bernard Barber and published by Routledge. This book was released on 2018-04-24 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of human subjects in biomedical research has increased rapidly with scientific discoveries. However, the failure to achieve the highest - or even adequate - standards of professional moral concern and behavior is a serious side effect. Research on Human Subjects is based on four years of intensive research in which two studies were completed - one on a nationally representative sample of biomedical research institutions, the second on a sample of 350 researchers who actually used human subjects. The authors explore prevalent ethical norms, the actual ethical behavior of scientists, and the dilemma between the values of humane therapy and scientific discovery. They document the inadequate training that biomedical researchers receive in the ethics of research on human subjects, not only in medical schools but in post-graduate training as well. This landmark work makes very specific suggestions for policy change and reform for the biomedical research profession and its employment of human subjects.

Experimentation with Human Subjects

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Author :
Publisher : George Braziller
ISBN 13 :
Total Pages : 492 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Experimentation with Human Subjects by : Paul Abraham Freund

Download or read book Experimentation with Human Subjects written by Paul Abraham Freund and published by George Braziller. This book was released on 1970 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most of the essays appeared in the spring 1969 issue of Dædalus.

Animal Experimentation: Working Towards a Paradigm Change

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Publisher : BRILL
ISBN 13 : 9004391193
Total Pages : 749 pages
Book Rating : 4.0/5 (43 download)

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Book Synopsis Animal Experimentation: Working Towards a Paradigm Change by : Kathrin Herrmann

Download or read book Animal Experimentation: Working Towards a Paradigm Change written by Kathrin Herrmann and published by BRILL. This book was released on 2019-04-30 with total page 749 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animal experimentation has been one of the most controversial areas of animal use, mainly due to the intentional harms inflicted upon animals for the sake of hoped-for benefits in humans. Despite this rationale for continued animal experimentation, shortcomings of this practice have become increasingly more apparent and well-documented. However, these limitations are not yet widely known or appreciated, and there is a danger that they may simply be ignored. The 51 experts who have contributed to Animal Experimentation: Working Towards a Paradigm Change critically review current animal use in science, present new and innovative non-animal approaches to address urgent scientific questions, and offer a roadmap towards an animal-free world of science.

Medical Apartheid

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Publisher : Vintage
ISBN 13 : 076791547X
Total Pages : 530 pages
Book Rating : 4.7/5 (679 download)

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Book Synopsis Medical Apartheid by : Harriet A. Washington

Download or read book Medical Apartheid written by Harriet A. Washington and published by Vintage. This book was released on 2008-01-08 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: NATIONAL BOOK CRITICS CIRCLE AWARD WINNER • The first full history of Black America’s shocking mistreatment as unwilling and unwitting experimental subjects at the hands of the medical establishment. No one concerned with issues of public health and racial justice can afford not to read this masterful book. "[Washington] has unearthed a shocking amount of information and shaped it into a riveting, carefully documented book." —New York Times From the era of slavery to the present day, starting with the earliest encounters between Black Americans and Western medical researchers and the racist pseudoscience that resulted, Medical Apartheid details the ways both slaves and freedmen were used in hospitals for experiments conducted without their knowledge—a tradition that continues today within some black populations. It reveals how Blacks have historically been prey to grave-robbing as well as unauthorized autopsies and dissections. Moving into the twentieth century, it shows how the pseudoscience of eugenics and social Darwinism was used to justify experimental exploitation and shoddy medical treatment of Blacks. Shocking new details about the government’s notorious Tuskegee experiment are revealed, as are similar, less-well-known medical atrocities conducted by the government, the armed forces, prisons, and private institutions. The product of years of prodigious research into medical journals and experimental reports long undisturbed, Medical Apartheid reveals the hidden underbelly of scientific research and makes possible, for the first time, an understanding of the roots of the African American health deficit. At last, it provides the fullest possible context for comprehending the behavioral fallout that has caused Black Americans to view researchers—and indeed the whole medical establishment—with such deep distrust.

Dangerous Medicine

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Publisher : Yale University Press
ISBN 13 : 0300262450
Total Pages : 305 pages
Book Rating : 4.3/5 (2 download)

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Book Synopsis Dangerous Medicine by : Sydney A. Halpern

Download or read book Dangerous Medicine written by Sydney A. Halpern and published by Yale University Press. This book was released on 2021-11-23 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: The untold history of America’s mid-twentieth-century program of hepatitis infection research, its scientists’ aspirations, and the damage the project caused human subjects From 1942 through 1972, American biomedical researchers deliberately infected people with hepatitis. Government-sponsored researchers were attempting to discover the basic features of the disease and the viruses causing it, and to develop interventions that would quell recurring outbreaks. Drawing from extensive archival research and in-person interviews, Sydney Halpern traces the hepatitis program from its origins in World War II through its expansion during the initial Cold War years, to its demise in the early 1970s amid an outcry over research abuse. The subjects in hepatitis studies were members of stigmatized groups—conscientious objectors, prison inmates, the mentally ill, and developmentally disabled adults and children. The book reveals how researchers invoked military and scientific imperatives and the rhetoric of a common good to win support for the experiments and access to recruits. Halpern examines the participants’ long-term health consequences and raises troubling questions about hazardous human experiments aimed at controlling today’s epidemic diseases.

The Use of Human Beings in Research

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Publisher : Springer Science & Business Media
ISBN 13 : 9400927053
Total Pages : 301 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis The Use of Human Beings in Research by : S.F. Spicker

Download or read book The Use of Human Beings in Research written by S.F. Spicker and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume, which has developed from the Fourteenth Trans Disciplinary Symposium on Philosophy and Medicine, September 5-8, 1982, at Tel Aviv University, Israel, contains the contributions of a group of distinguished scholars who together examine the ethical issues raised by the advance of biomedical science and technology. We are, of course, still at the beginning of a revolution in our understanding of human biology; scientific medicine and clinical research are scarcely one hundred years old. Both the sciences and the technology of medicine until ten or fifteen years ago had the feeling of the 19th century about them; we sense that they belonged to an older time; that era is ending. The next twenty-five to fifty years of investigative work belong to neurobiology, genetics, and reproductive biology. The technologies of information processing and imaging will make diagnosis and treatment almost incomprehensible by my generation of physicians. Our science and technology will become so powerful that we shall require all of the art and wisdom we can muster to be sure that they remain dedicated, as Francis Bacon hoped four centuries ago, "to the uses of life." It is well that, as philosophers and physicians, we grapple with the issues now when they are relatively simple, and while the pace of change is relatively slow. We require a strategy for the future; that strategy must be worked out by scientists, philosophers, physicians, lawyers, theologians, and, I should like to add, artists and poets.

Acres of Skin

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Publisher : Routledge
ISBN 13 : 1134001649
Total Pages : 344 pages
Book Rating : 4.1/5 (34 download)

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Book Synopsis Acres of Skin by : Allen M. Hornblum

Download or read book Acres of Skin written by Allen M. Hornblum and published by Routledge. This book was released on 2013-05-13 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: At a time of increased interest and renewed shock over the Tuskegee syphilis experiments, Acres of Skin sheds light on yet another dark episode of American medical history. In this disturbing expose, Allen M. Hornblum tells the story of Philadelphia's Holmesburg Prison.

Against Their Will

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Publisher : St. Martin's Press
ISBN 13 : 1137363452
Total Pages : 284 pages
Book Rating : 4.1/5 (373 download)

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Book Synopsis Against Their Will by : Allen M. Hornblum

Download or read book Against Their Will written by Allen M. Hornblum and published by St. Martin's Press. This book was released on 2013-06-25 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the Cold War, an alliance between American scientists, pharmaceutical companies, and the US military pushed the medical establishment into ethically fraught territory. Doctors and scientists at prestigious institutions were pressured to produce medical advances to compete with the perceived threats coming from the Soviet Union. In Against Their Will, authors Allen Hornblum, Judith Newman, and Gregory Dober reveal the little-known history of unethical and dangerous medical experimentation on children in the United States. Through rare interviews and the personal correspondence of renowned medical investigators, they document how children—both normal and those termed "feebleminded"—from infants to teenagers, became human research subjects in terrifying experiments. They were drafted as "volunteers" to test vaccines, doused with ringworm, subjected to electric shock, and given lobotomies. They were also fed radioactive isotopes and exposed to chemical warfare agents. This groundbreaking book shows how institutional superintendents influenced by eugenics often turned these children over to scientific researchers without a second thought. Based on years of archival work and numerous interviews with both scientific researchers and former test subjects, this is a fascinating and disturbing look at the dark underbelly of American medical history.