Human Blood Cells Consequences Of Genetic Polymorphisms And Variations

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Human Blood Cells: Consequences Of Genetic Polymorphisms And Variations

Author : May-jean King
Publisher : World Scientific
ISBN 13 : 1911298933
Total Pages : 420 pages
Book Rating : 4.9/5 (112 download)

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Book Synopsis Human Blood Cells: Consequences Of Genetic Polymorphisms And Variations by : May-jean King

Download or read book Human Blood Cells: Consequences Of Genetic Polymorphisms And Variations written by May-jean King and published by World Scientific. This book was released on 2000-07-04 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: This important book uses selected molecules expressed on erythrocytes, lymphocytes, platelets and granulocytes to illustrate how genetic polymorphisms and variations in these molecules can affect their structure and function in mature human blood cells. The examples described tend to have a clinical association. Human blood group antigens and HLA antigens are classic examples of genetic polymorphism and they are important in blood transfusion and organ transplantation, respectively. In common with the blood group antigens, the polymorphic and variant antigens on platelets and granulocytes can be targets for antibodies in feto-maternal antigen incompatibility and transfusion reactions. Certain inherited haemolytic anaemias can be attributed to some of the polymorphic and variant forms of erythrocyte anion transport protein, spectrin, and glucose-6-phosphate dehydrogenase which exhibit abnormal structural or functional properties. Similarly, the study of cytokine gene polymorphism can provide a further understanding of the immune/inflammatory diseases and allogeneic transplantation./a

Human Blood Cells

Author : Mary-Jean King
Publisher : World Scientific Publishing Company
ISBN 13 : 9789810239374
Total Pages : 270 pages
Book Rating : 4.2/5 (393 download)

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Book Synopsis Human Blood Cells by : Mary-Jean King

Download or read book Human Blood Cells written by Mary-Jean King and published by World Scientific Publishing Company. This book was released on 1999-01-01 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: This important book uses selected molecules expressed on erythrocytes, lymphocytes, platelets and granulocytes to illustrate how genetic polymorphisms and variations in these molecules can affect their structure and function in mature human blood cells. The examples described tend to have a clinical association. Human blood group antigens and HLA antigens are classic examples of genetic polymorphism and they are important in blood transfusion and organ transplantation, respectively. In common with the blood group antigens, the polymorphic and variant antigens on platelets and granulocytes can be targets for antibodies in feto-maternal antigen incompatibility and transfusion reactions. Certain inherited haemolytic anaemias can be attributed to some of the polymorphic and variant forms of erythrocyte anion transport protein, spectrin, and glucose-6-phosphate dehydrogenase which exhibit abnormal structural or functional properties. Similarly, the study of cytokine gene polymorphism can provide a further understanding of the immune/inflammatory diseases and allogeneic transplantation.

The Recent Topics in Genetic Polymorphisms

Author : Mahmut Çalışkan
Publisher : BoD – Books on Demand
ISBN 13 : 1789858917
Total Pages : 149 pages
Book Rating : 4.7/5 (898 download)

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Book Synopsis The Recent Topics in Genetic Polymorphisms by : Mahmut Çalışkan

Download or read book The Recent Topics in Genetic Polymorphisms written by Mahmut Çalışkan and published by BoD – Books on Demand. This book was released on 2020-05-13 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book in your hands presents chapters revealing the magnitude of genetic polymorphisms that exist in different kinds of living beings. Natural populations contain a considerable amount of genetic change, which provides a genomic flexibility that can be used as a raw material for adaptation to changing environmental conditions. The analysis of genetic polymorphisms provides information about DNA sequence changes at a given locus. The increasing availability of PCR-based molecular markers allows for the detailed analyses and the detection of genetic changes influencing some important traits. The purpose of this book is to provide a glimpse into the dynamic process of genetic polymorphisms by presenting the thoughts of scientists engaged in the generation of new ideas and techniques employed for the assessment of genetic polymorphisms. The book should prove useful to students, researchers and experts in the area of molecular genetics.

Desk Reference for Hematology

Author : N.K. Shinton
Publisher : CRC Press
ISBN 13 : 142000512X
Total Pages : 1030 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Desk Reference for Hematology by : N.K. Shinton

Download or read book Desk Reference for Hematology written by N.K. Shinton and published by CRC Press. This book was released on 2007-12-19 with total page 1030 pages. Available in PDF, EPUB and Kindle. Book excerpt: A cross between a dictionary and an encyclopedia, Desk Reference for Hematology, Second Edition presents a concise yet thorough examination of hematology and its relationship with other systems and disorders. The 1500 alphabetically listed articles provide quick and easy access to expert information, the 150 tables put precise data at your f

Advances in Malaria Research

Author : Deepak Gaur
Publisher : John Wiley & Sons
ISBN 13 : 1118493796
Total Pages : 611 pages
Book Rating : 4.1/5 (184 download)

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Book Synopsis Advances in Malaria Research by : Deepak Gaur

Download or read book Advances in Malaria Research written by Deepak Gaur and published by John Wiley & Sons. This book was released on 2016-12-27 with total page 611 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thoroughly reviews our current understanding of malarial biology Explores the subject with insights from post-genomic technologies Looks broadly at the disease, vectors of infection, and treatment and prevention strategies A timely publication with chapters written by global researchers leaders

Infectious Disease and Host-Pathogen Evolution

Author : Krishna R. Dronamraju
Publisher : Cambridge University Press
ISBN 13 : 1139451693
Total Pages : 394 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Infectious Disease and Host-Pathogen Evolution by : Krishna R. Dronamraju

Download or read book Infectious Disease and Host-Pathogen Evolution written by Krishna R. Dronamraju and published by Cambridge University Press. This book was released on 2004-04-05 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, originally published in 2004, is concerned with the links between human evolution and infectious disease. It has long been recognised that an important factor in human evolution has been the struggle against infectious disease and, more recently, it was revealed that complex genetic polymorphisms are the direct result of that struggle.

The Blood of Sheep

Author : M.H. Blunt
Publisher : Springer Science & Business Media
ISBN 13 : 3642661157
Total Pages : 233 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis The Blood of Sheep by : M.H. Blunt

Download or read book The Blood of Sheep written by M.H. Blunt and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this monograph is to bring together in one volume some of the more recent knowledge of the cellular and biochemical constit uents of sheep's blood. Limitations of the space available have precluded a complete discus sion, but a number of good reviews have been published within the last few years on certain specific aspects and these have been referred to in the extensive bibliography. There is inevitably some overlap in the material discussed arising from duplication of interest and from the close association of the subject matter. The authors were asked to discuss normal values and the changes brought about in these by physiological stresses, particularly those imposed by pregnancy, age, lactation, and changing nutrition. In some cases, where it was considered suJtable, the response to certain pathological conditions have also been discussed. It is hoped that the monograph will be of value to those using sheep in comparative research into veterinary and human medicine as well as to students of ruminant physiology. Wellington/New Zealand, April 1975 M. H. BLUNT Table of Contents Distribution and Dynamics of Body Fluids in Sheep W.V. MACFARLANE. With 1 Figure .................................. . Introduction .................................................... .

Disorders of Hemoglobin

Author : Martin H. Steinberg
Publisher : Cambridge University Press
ISBN 13 : 0521875196
Total Pages : 883 pages
Book Rating : 4.5/5 (218 download)

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Book Synopsis Disorders of Hemoglobin by : Martin H. Steinberg

Download or read book Disorders of Hemoglobin written by Martin H. Steinberg and published by Cambridge University Press. This book was released on 2009-08-17 with total page 883 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised new edition of the definitive reference on disorders of hemoglobin.

Microbial Host-interaction

Author : Per Brandtzaeg
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805591675
Total Pages : 278 pages
Book Rating : 4.8/5 (55 download)

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Book Synopsis Microbial Host-interaction by : Per Brandtzaeg

Download or read book Microbial Host-interaction written by Per Brandtzaeg and published by Karger Medical and Scientific Publishers. This book was released on 2009 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most indigenous microbes occur in the intestinal tract, and their interactions with the host are largely unknown. Current understanding of host-microbe interactions links early microbial contact to the origin of disease, a theory that has its roots in the hygiene hypothesis. Modern life style appears to deprive the infant of conditions that provide adequate anti-inflammatory or tolerogenic stimuli upon antigen encounter. Thus, maturational signals from the environment and the diet are insufficient to adequately shape the immune system. This publication deals with the relationship between the gut microbiota as well as altered pattern of early microbial contact and the origin of human disease. New aspects of the original hygiene hypothesis are discussed in relation to disorders spanning from allergy and autoimmunity to obesity.The results presented suggest that all these disorders may be linked to aberrant antigen absorption and immune responses associated with dysfunction of mucosal defense. Researchers, clinicians and students interested in the interaction of the host with indigenous gut bacteria and the consequences for human health will find this publication of utmost interest.

Nature Encyclopedia of the Human Genome: Genome databases - Mitochondrial genome: Evolution

Author : David Neil Cooper
Publisher :
ISBN 13 :
Total Pages : 1072 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Nature Encyclopedia of the Human Genome: Genome databases - Mitochondrial genome: Evolution by : David Neil Cooper

Download or read book Nature Encyclopedia of the Human Genome: Genome databases - Mitochondrial genome: Evolution written by David Neil Cooper and published by . This book was released on 2003 with total page 1072 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Brenner's Encyclopedia of Genetics

Author : Stanley Maloy
Publisher : Academic Press
ISBN 13 : 0080961568
Total Pages : 4360 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Brenner's Encyclopedia of Genetics by : Stanley Maloy

Download or read book Brenner's Encyclopedia of Genetics written by Stanley Maloy and published by Academic Press. This book was released on 2013-03-03 with total page 4360 pages. Available in PDF, EPUB and Kindle. Book excerpt: The explosion of the field of genetics over the last decade, with the new technologies that have stimulated research, suggests that a new sort of reference work is needed to keep pace with such a fast-moving and interdisciplinary field. Brenner's Encyclopedia of Genetics, Second Edition, Seven Volume Set, builds on the foundation of the first edition by addressing many of the key subfields of genetics that were just in their infancy when the first edition was published. The currency and accessibility of this foundational content will be unrivalled, making this work useful for scientists and non-scientists alike. Featuring relatively short entries on genetics topics written by experts in that topic, Brenner's Encyclopedia of Genetics, Second Edition, Seven Volume Set provides an effective way to quickly learn about any aspect of genetics, from Abortive Transduction to Zygotes. Adding to its utility, the work provides short entries that briefly define key terms, and a guide to additional reading and relevant websites for further study. Many of the entries include figures to explain difficult concepts. Key terms in related areas such as biochemistry, cell, and molecular biology are also included, and there are entries that describe historical figures in genetics, providing insights into their careers and discoveries. This 7-volume set represents a 25% expansion from the first edition, with over 1600 articles encompassing this burgeoning field Thoroughly up-to-date, with many new topics and subfields covered that were in their infancy or not inexistence at the time of the first edition. Timely coverage of emergent areas such as epigenetics, personalized genomic medicine, pharmacogenetics, and genetic enhancement technologies Interdisciplinary and global in its outlook, as befits the field of genetics Brief articles, written by experts in the field, which not only discuss, define, and explain key elements of the field, but also provide definition of key terms, suggestions for further reading, and biographical sketches of the key people in the history of genetics

Ecology of parasite-vector interactions

Author : Willem Takken
Publisher : Springer
ISBN 13 : 9086867448
Total Pages : 275 pages
Book Rating : 4.0/5 (868 download)

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Book Synopsis Ecology of parasite-vector interactions by : Willem Takken

Download or read book Ecology of parasite-vector interactions written by Willem Takken and published by Springer. This book was released on 2013-03-15 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vector-borne diseases continue to be one of the most important determinants affecting human and animal health. Large numbers of people suffer from diseases like malaria, dengue, filariasis and leishmaniasis, especially in the tropics. Whereas these diseases were eradicated from the temperate climate zones, in recent years the rising incidence of 'emerging' vector-borne diseases such as bluetongue, West Nile Virus, Lyme disease, tick-borne encephalitis and the recent outbreaks of chikungunya and dengue in southern Europe provide evidence that these diseases are resilient and can disperse to other regions and continents where before they were not present or relevant. Many tools for the management of vector-borne diseases are currently under pressure because of increasing drug and insecticide resistance, as well as the realization of biological variation of parasites and vectors and their ecosystems. At the same time, progress in our understanding of genetics, immunology, population biology and epidemiology allow for a better understanding of parasite-vector interactions. Here the state-of-the-art of these interactions is being reviewed, and means for using this information for advanced strategies of vector-borne disease control are proposed. This 3rd edition of ECVD aims to provide a rapid overview of recent developments in the field of parasite-vector interactions and how this can be used for more effective and sustainable disease control.

Cancer Prevention

Author : H.-J. Senn
Publisher : Springer Science & Business Media
ISBN 13 : 3540376968
Total Pages : 243 pages
Book Rating : 4.5/5 (43 download)

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Book Synopsis Cancer Prevention by : H.-J. Senn

Download or read book Cancer Prevention written by H.-J. Senn and published by Springer Science & Business Media. This book was released on 2007-05-26 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains the main proceedings of the fourth international conference on "Cancer Prevention 2006," which was held during February 16–18, 2006, in St. Gallen, Switzerland. Written by international experts in the field, the book comprises a comprehensive update on the most recent developments in the upsurging fields of molecular biology and cancer genetics and their interactions with clinical epidemiology and cancer prevention at various levels.

Research Awards Index

Author :
Publisher :
ISBN 13 :
Total Pages : 1258 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Research Awards Index by :

Download or read book Research Awards Index written by and published by . This book was released on 1976 with total page 1258 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Human Genetic Diversity

Author : Julian C. Knight
Publisher : Oxford University Press on Demand
ISBN 13 : 0199227691
Total Pages : 501 pages
Book Rating : 4.1/5 (992 download)

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Book Synopsis Human Genetic Diversity by : Julian C. Knight

Download or read book Human Genetic Diversity written by Julian C. Knight and published by Oxford University Press on Demand. This book was released on 2009-08-06 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the remarkable progress which has been made in defining the extent and nature of human genetic variation. It provides a framework for understanding how research in this area is revolutionising our knowledge of human origins and the genetic basis of disease, as well as common traits such as obesity.

Arteriogenesis

Author : Wolfgang Schaper
Publisher : Springer Science & Business Media
ISBN 13 : 140208126X
Total Pages : 371 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Arteriogenesis by : Wolfgang Schaper

Download or read book Arteriogenesis written by Wolfgang Schaper and published by Springer Science & Business Media. This book was released on 2006-04-11 with total page 371 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emphasizes the research activities of Germany’s Nauheim Institute of the Max Planck Society and its group of investigators both past and present, in the field of collateral artery growth. Incorporates a multidisciplinary in vivo approach to the study of arteriogenesis that includes molecular approaches with classical physiology and immunohistochemistry. Full color throughout and well illustrated.

Textbook of Personalized Medicine

Author : Kewal K. Jain
Publisher : Humana Press
ISBN 13 : 1493925539
Total Pages : 762 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Textbook of Personalized Medicine by : Kewal K. Jain

Download or read book Textbook of Personalized Medicine written by Kewal K. Jain and published by Humana Press. This book was released on 2015-03-17 with total page 762 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in the technology used in personalized medicine and increased applications for clinical use have created a need for this expansion and revision of Kewal K. Jain’s Textbook of Personalized Medicine. As the first definitive work on this topic, this book reviews the fundamentals and development of personalized medicine and subsequent adoptions of the concepts by the biopharmaceutical industry and the medical profession. It also discusses examples of applications in key therapeutic areas, as well as ethical and regulatory issues, providing a concise and comprehensive source of reference for those involved in healthcare management, planning and politics. Algorithms are included as a guide to those involved in the management of important diseases where decision-making is involved due to the multiple choices available. Textbook of Personalized Medicine, Second Edition will serve as a convenient source of information for physicians, scientists, decision makers in the biopharmaceutical and healthcare industries and interested members of the public.