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Honorary Doctorate Dr Katalin Kariko
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Book Synopsis Honorary Doctorate Dr. Katalin Karikó by : Katalin Karikó
Download or read book Honorary Doctorate Dr. Katalin Karikó written by Katalin Karikó and published by Radboud University Press. This book was released on with total page 34 pages. Available in PDF, EPUB and Kindle. Book excerpt: On 20 October 2022, the day that Radboud University celebrated its 99th anniversary, Dr. Katalin Karikó received a Radboud honorary doctorate in recognition of her scientific contributions to developing mRNA-based vaccines. This edition includes the laudatio of the honorary supervisor and the speech of the honorary doctor. Karikó spent years researching medical applications of mRNA. Her dream was to develop synthetic mRNA and use this to cure cancer, strokes, and influenza. Eventually, after years of toil, rejection, and criticism from colleagues, she and fellow researcher Drew Weissman demonstrated that it is possible to trigger an immune response in the body with mRNA without the body turning against the mRNA itself. With this breakthrough, a new revolutionary technique was born. Thanks to Karikó’s scientific work, BioNTech/Pfizer and Moderna were able to develop the current mRNA vaccines against COVID-19. A prime example of the beneficial impact that fundamental research can eventually have on society.
Book Synopsis Breaking Through by : Katalin Karikó
Download or read book Breaking Through written by Katalin Karikó and published by Random House. This book was released on 2024-10-08 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: A powerful memoir from Katalin Karikó, winner of the 2023 Nobel Prize in Physiology or Medicine, whose decades-long research led to the COVID-19 vaccines “Katalin Karikó’s story is an inspiration.”—Bill Gates “Riveting . . . a true story of a brilliant biochemist who never gave up or gave in.”—Bonnie Garmus, author of Lessons in Chemistry A KIRKUS REVIEWS BEST BOOK OF THE YEAR Katalin Karikó has had an unlikely journey. The daughter of a butcher in postwar communist Hungary, Karikó grew up in an adobe home that lacked running water, and her family grew their own vegetables. She saw the wonders of nature all around her and was determined to become a scientist. That determination eventually brought her to the United States, where she arrived as a postdoctoral fellow in 1985 with $1,200 sewn into her toddler’s teddy bear and a dream to remake medicine. Karikó worked in obscurity, battled cockroaches in a windowless lab, and faced outright derision and even deportation threats from her bosses and colleagues. She balked as prestigious research institutions increasingly conflated science and money. Despite setbacks, she never wavered in her belief that an ephemeral and underappreciated molecule called messenger RNA could change the world. Karikó believed that someday mRNA would transform ordinary cells into tiny factories capable of producing their own medicines on demand. She sacrificed nearly everything for this dream, but the obstacles she faced only motivated her, and eventually she succeeded. Karikó’s three-decade-long investigation into mRNA would lead to a staggering achievement: vaccines that protected millions of people from the most dire consequences of COVID-19. These vaccines are just the beginning of mRNA’s potential. Today, the medical community eagerly awaits more mRNA vaccines—for the flu, HIV, and other emerging infectious diseases. Breaking Through isn’t just the story of an extraordinary woman. It’s an indictment of closed-minded thinking and a testament to one woman’s commitment to laboring intensely in obscurity—knowing she might never be recognized in a culture that is driven by prestige, power, and privilege—because she believed her work would save lives.
Book Synopsis Félix d`Herelle and the Origins of Molecular Biology by : William C. Summers
Download or read book Félix d`Herelle and the Origins of Molecular Biology written by William C. Summers and published by Yale University Press. This book was released on 1999-06-10 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: A self-taught scientist determined to bring science out of the laboratory and into the practical arena, French-Canadian Felix d’Herelle (1873-1949) made history in two different fields of biology. Not only was he first to demonstrate the use and application of bacteria for biological control of insect pests, he also became a seminal figure in the history of molecular biology. This engaging book is the first full biography of d’Herelle, a complex figure who emulated Louis Pasteur and influenced the course of twentieth-century biology, yet remained a controversial outsider to the scientific community. Drawing on family papers, archival sources, interviews, and d’Herelle’s published and unpublished writings, Dr. William C. Summers tells the fascinating story of the scientist’s life and the work that took him around the globe. In 1917, d’Herelle published the first paper describing the phenomenon of the bacteriophage and its biological nature. A series of more than 110 articles and 6 major books followed, in which d’Herelle established the foundation for the later work of the Phage Group in molecular biology. Yet d’Herelle sometimes inspired animosity in others--he was drummed out of the Pasteur Institute, he held only one brief permanent position in the scientific establishment (at Yale University from 1928 to 1933), and he was bewildered by the social nuances of the world of international science. His story is more than the biography of a single brilliant scientist; it is also a fascinating chapter in the history of biology.
Download or read book The Messenger written by Peter Loftus and published by Harvard Business Press. This book was released on 2022-07-26 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: The inside story of an unprecedented feat of science and business. At the start of 2020, Moderna was a biotech unicorn with dim prospects. Yes, there was the promise of its disruptive innovation that could transform medicine by using something called messenger RNA, one of the body's building blocks of life, to combat disease. But its stock was under water. There were reports of a toxic work culture. And despite ten years of work, the company was still years away from delivering its first product. Investors were getting antsy, or worse, skeptical. Then the pandemic hit, and Moderna, at first reluctantly, became a central player in a global drama—a David to Big Pharma's Goliaths—turning its technology toward breaking the global grip of the terrible disease. By year's end, with the virus raging, Moderna delivered one of the world's first Covid-19 vaccines, with a stunningly high rate of protection. The achievement gave the world a way out of a crippling pandemic while validating Moderna's technology, transforming the company into a global industry power. Biotech, and the venture capital community that fuels it, will never be the same. Wall Street Journal reporter Peter Loftus, veteran reporter covering the pharmaceutical and biotech industries and part of a Pulitzer Prize–finalist team, brings the inside story of Moderna, from its humble start at a casual lunch through its heady startup days, into the heart of the pandemic and beyond. With deep access to all of the major players, Loftus weaves a tale of science and business that brings to life Moderna's monumental feat of creating a vaccine that beat back a deadly virus and changed the business of medicine forever. The Messenger spans a decade and is full of heroic efforts by ordinary people, lucky breaks, and life-and-death decisions. It's the story of a revolutionary idea, the evolution of a cutting-edge American industry, and one of the great achievements of this century.
Book Synopsis An American Odyssey by : Mary Schmidt Campbell
Download or read book An American Odyssey written by Mary Schmidt Campbell and published by Oxford University Press. This book was released on 2018-08-06 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt: By the time of his death in 1988, Romare Bearden was most widely celebrated for his large-scale public murals and collages, which were reproduced in such places as Time and Esquire to symbolize and evoke the black experience in America. As Mary Schmidt Campbell shows us in this definitive, defining, and immersive biography, the relationship between art and race was central to his life and work -- a constant, driving creative tension. Bearden started as a cartoonist during his college years, but in the later 1930s turned to painting and became part of a community of artists supported by the WPA. As his reputation grew he perfected his skills, studying the European masters and analyzing and breaking down their techniques, finding new ways of applying them to the America he knew, one in which the struggle for civil rights became all-absorbing. By the time of the March on Washington in 1963, he had begun to experiment with the Projections, as he called his major collages, in which he tried to capture the full spectrum of the black experience, from the grind of daily life to broader visions and aspirations. Campbell's book offers a full and vibrant account of Bearden's life -- his years in Harlem (his studio was above the Apollo theater), to his travels and commissions, along with illuminating analysis of his work and artistic career. Campbell, who met Bearden in the 1970s, was among the first to compile a catalogue of his works. An American Odyssey goes far beyond that, offering a living portrait of an artist and the impact he made upon the world he sought both to recreate and celebrate.
Book Synopsis Fundamentals of Epidemiology by : Lauren Christiansen-Lindquist, PhD, MPH
Download or read book Fundamentals of Epidemiology written by Lauren Christiansen-Lindquist, PhD, MPH and published by Springer Publishing Company. This book was released on 2024-02-07 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamentals of Epidemiology is a foundational resource that equips students with a strong understanding of both the principles and real-world applications of the science of public health. Its applied approach, demonstrating epidemiological concepts in action in a variety of different settings, uniquely prepares students for the challenges and exciting opportunities of this dynamic field. This engaging textbook cultivates a strong knowledge base through an explanation of the history of epidemiology and its core concepts, while providing a framework for critical thinking about public health topics. Other foundational concepts are then described and explored in the context of the real world, including descriptive epidemiology and surveillance, analytic epidemiology, study designs, effect measure modification, systematic and random error, and data analysis and modeling. Building from chapter to chapter, the textbook reinforces key concepts and their applications to the field while also confronting head-on many common mistakes that new learners of epidemiology make. This textbook incorporates thoughtful public health examples, scenarios, and descriptions that foster the investigative mindset and problem-solving approach that is needed in epidemiology. With abundant illustrations, historical vignettes, case examples, and practice problems covering topics such as social determinants of health, infectious disease, applications of epidemiology to policy and more, this inviting textbook prepares students to think like an epidemiologist, equipping them with the fundamentals essential for careers in public health, medicine, nursing, and other health professions. Key Features Provides a more logical sequence for learning epidemiology, with iterative learning strategies aimed at reinforcing key concepts Includes an in-depth focus on surveillance and descriptive epidemiology Discusses causality, counterfactual thinking, and exchangeability at a level appropriate for new learners of epidemiology Provides problem-based learning examples that encompass diverse settings and populations, and links to other health disciplines (health policy, health economics, behavioral sciences, environmental health) Presents visuals in a consistent manner to foster a sound understanding of the core epidemiological principles Qualified instructors also have access to a full suite of instructor resources
Book Synopsis NO More Heart Disease by : Louis Ignarro
Download or read book NO More Heart Disease written by Louis Ignarro and published by St. Martin's Press. This book was released on 2006-01-24 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Louis Ignarro discovered "the atom" of cardiovascular health--a tiny molecule called Nitric Oxide. NO, as it is known by chemists, is a signaling molecule produced by the body, and is a vasodilator that helps control blood flow to every part of the body. Dr. Ignarro's findings led to the development of Viagra. Nitric Oxide has a beneficial effect on the cardiovascular system as well. NO relaxes and enlarges the blood vessels, prevents blood clots that trigger strokes and heart attacks, and regulates blood pressure and the accumulation of plaque in the blood vessels. Dr. Ignarro's current research indicates that Nitric Oxide may help lower cholesterol by facilitating the actions of statin drugs like Lipitor. The goal of the regimen presented in NO More Heart Disease is to age proof the cardiovascular system, keeping the vascular network clean and elastic through enhanced NO productivity. The plan is easy-to-follow without extreme lifestyle adjustments, involving taking supplements to stimulate Nitric Oxide production, incorporating NO friendly food into the diet, and a moderate exercise program.
Book Synopsis U.S. National Library of Medicine by : Jeffrey S. Reznick
Download or read book U.S. National Library of Medicine written by Jeffrey S. Reznick and published by Arcadia Publishing. This book was released on 2017-06-26 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: The US National Library of Medicine, on the campus of the National Institutes of Health in Bethesda, Maryland, has been a center of information innovation since its beginnings in the early 19th century. The world's largest medical library and a federal government agency, it maintains and makes publicly available a diverse and world-renowned collection of materials dating from the 11th to the 21st centuries, and it produces a variety of electronic resources that millions of people around the globe search billions of times each year. The library also supports and conducts research, development, and training in biomedical informatics and health information technology, and it coordinates the National Network of Libraries of Medicine that promotes and provides access to health information in communities across the United States. As the library anticipates its third century of public service, this book offers a visual history of its development from its earliest days through the late 20th century, as the institution has involved generations of visionary leaders and dedicated individuals who experienced the American Civil War, the world wars, the Cold War, and the dawn of the information age.
Book Synopsis What Inclusive Instructors Do by : Tracie Marcella Addy
Download or read book What Inclusive Instructors Do written by Tracie Marcella Addy and published by Taylor & Francis. This book was released on 2023-07-03 with total page 153 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inclusive instruction is teaching that recognizes and affirms a student's social identity as an important influence on teaching and learning processes, and that works to create an environment in which students are able to learn from the course, their peers, and the teacher while still being their authentic selves. It works to disrupt traditional notions of who succeeds in the classroom and the systemic inequities inherent in traditional educational practices.—Full-time Academic Professional, Doctorate-granting University, EducationThis book uniquely offers the distilled wisdom of scores of instructors across ranks, disciplines and institution types, whose contributions are organized into a thematic framework that progressively introduces the reader to the key dispositions, principles and practices for creating the inclusive classroom environments (in person and online) that will help their students succeed. The authors asked the hundreds of instructors whom they surveyed as part of a national study to define what inclusive teaching meant to them and what inclusive teaching approaches they implemented in their courses. The instructors’ voices ring loudly as the authors draw on their responses, building on their experiences and expertise to frame the conversation about what inclusive teachers do. The authors in addition describe their own insights and practices, integrating and discussing current literature relevant to inclusive teaching to ensure a research-supported approach.Inclusive teaching is no longer an option but a vital teaching competency as our classrooms fill with racially diverse, first generation, and low income and working class students who need a sense of belonging and recognition to thrive and contribute to the construction of knowledge.The book unfolds as an informal journey that allows the reader to see into other teachers’ practices. With questions for reflection embedded throughout the book, the authors provide the reader with an inviting and thoughtful guide to develop their own inclusive teaching practices.By utilizing the concepts and principles in this book readers will be able to take steps to transform their courses into spaces that are equitable and welcoming, and adopt practical strategies to address the various inclusion issues that can arise.The book will also appeal to educational developers and staff who support instructors in their inclusive teaching efforts. It should find a place in reflective workshops, book clubs and learning communities exploring this important topic.
Book Synopsis A Crack In Creation by : Jennifer A. Doudna
Download or read book A Crack In Creation written by Jennifer A. Doudna and published by HarperCollins. This book was released on 2017-06-13 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: BY THE WINNER OF THE 2020 NOBEL PRIZE IN CHEMISTRY | Finalist for the Los Angeles Times Book Prize “A powerful mix of science and ethics . . . This book is required reading for every concerned citizen—the material it covers should be discussed in schools, colleges, and universities throughout the country.”— New York Review of Books Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. That is, until 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the gene-editing tool CRISPR—a revolutionary new technology that she helped create—to make heritable changes in human embryos. The cheapest, simplest, most effective way of manipulating DNA ever known, CRISPR may well give us the cure to HIV, genetic diseases, and some cancers. Yet even the tiniest changes to DNA could have myriad, unforeseeable consequences, to say nothing of the ethical and societal repercussions of intentionally mutating embryos to create “better” humans. Writing with fellow researcher Sam Sternberg, Doudna—who has since won the Nobel Prize for her CRISPR research—shares the thrilling story of her discovery and describes the enormous responsibility that comes with the power to rewrite the code of life. “The future is in our hands as never before, and this book explains the stakes like no other.” — George Lucas “An invaluable account . . . We owe Doudna several times over.” — Guardian
Book Synopsis Losing the Nobel Prize: A Story of Cosmology, Ambition, and the Perils of Science's Highest Honor by : Brian Keating
Download or read book Losing the Nobel Prize: A Story of Cosmology, Ambition, and the Perils of Science's Highest Honor written by Brian Keating and published by W. W. Norton & Company. This book was released on 2018-04-24 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Riveting."—Science A Forbes, Physics Today, Science News, and Science Friday Best Science Book Of 2018 Cosmologist and inventor of the BICEP (Background Imaging of Cosmic Extragalactic Polarization) experiment, Brian Keating tells the inside story of the mesmerizing quest to unlock cosmology’s biggest mysteries and the human drama that ensued. We follow along on a personal journey of revelation and discovery in the publish-or-perish world of modern science, and learn that the Nobel Prize might hamper—rather than advance—scientific progress. Fortunately, Keating offers practical solutions for reform, providing a vision of a scientific future in which cosmologists may finally be able to see all the way back to the very beginning.
Book Synopsis Writings on the Wall by : Kareem Abdul-Jabbar
Download or read book Writings on the Wall written by Kareem Abdul-Jabbar and published by Time Inc. Books. This book was released on 2016-08-23 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt: A New York Times and Washington Post Bestseller Bestselling author, basketball legend and cultural commentator Kareem Abdul-Jabbar explores the heart of issues that affect Americans today. Since retiring from professional basketball as the NBA's all-time leading scorer, six-time MVP, and Hall of Fame inductee, Kareem Abdul-Jabbar has become a lauded observer of culture and society, a New York Times bestselling author, and a regular contributor to The Washington Post, TIME magazine and TIME.com. He now brings that keen insight to the fore in Writings on the Wall: Searching for a New Equality Beyond Black and White, his most incisive and important work of non-fiction in years. He uses his unique blend of erudition, street smarts and authentic experience in essays on the country's seemingly irreconcilable partisan divide - both racial and political, parenthood, and his own experiences as an athlete, African-American, and a Muslim. The book is not just a collection of expositions; he also offers keen assessments of and solutions to problems such as racism in sports while speaking candidly about his experiences on the court and off. Timed for publication as the nation debates whom to send to the White House, the combination of plain talk on issues, life lessons, and personal stories places Writings on the Wall squarely in the middle of the conversation, as many of Abdul-Jabbar's topics are at the top of the national agenda. Whether it is sparring with Donald Trump, within the pages of TIME magazine, or full-length features in the The New York Times Magazine, writers, critics, and readers have come to agree on what The Washington Post observed: Abdul-Jabbar "has become a vital, dynamic and unorthodox cultural voice."
Book Synopsis Pursuing Sustainability by : Pamela Matson
Download or read book Pursuing Sustainability written by Pamela Matson and published by Princeton University Press. This book was released on 2016-03-29 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential guide to sustainable development for students and practitioners Sustainability is a global imperative and a scientific challenge like no other. This concise guide provides students and practitioners with a strategic framework for linking knowledge with action in the pursuit of sustainable development, and serves as an invaluable companion to more narrowly focused courses dealing with sustainability in particular sectors such as energy, food, water, and housing, or in particular regions of the world. Written by leading experts, Pursuing Sustainability shows how more inclusive and interdisciplinary approaches and systems perspectives can help you achieve your sustainability objectives. It stresses the need for understanding how capital assets are linked to sustainability goals through the complex adaptive dynamics of social-environmental systems, how committed people can use governance processes to alter those dynamics, and how successful interventions can be shaped through collaborations among researchers and practitioners on the ground. The ideal textbook for undergraduate and graduate students and an invaluable resource for anyone working in this fast-growing field, Pursuing Sustainability also features case studies, a glossary, and suggestions for further reading. Provides a strategic framework for linking knowledge with action Draws on the latest cutting-edge science and practices Serves as the ideal companion text to more narrowly focused courses Utilizes interdisciplinary approaches and systems perspectives Illustrates concepts with a core set of case studies used throughout the book Written by world authorities on sustainability An online illustration package is available to professors
Download or read book Granite written by Susan Butcher and published by University of Alaska Press. This book was released on 2007 with total page 38 pages. Available in PDF, EPUB and Kindle. Book excerpt: During a raging Arctic blizzard, Granite helps Susan and the rest of the dogs brave the storm and win the Iditarod.
Book Synopsis Principles and Practice of Clinical Trials by : Steven Piantadosi
Download or read book Principles and Practice of Clinical Trials written by Steven Piantadosi and published by Springer Nature. This book was released on 2022-07-19 with total page 2573 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a comprehensive major reference work for our SpringerReference program covering clinical trials. Although the core of the Work will focus on the design, analysis, and interpretation of scientific data from clinical trials, a broad spectrum of clinical trial application areas will be covered in detail. This is an important time to develop such a Work, as drug safety and efficacy emphasizes the Clinical Trials process. Because of an immense and growing international disease burden, pharmaceutical and biotechnology companies continue to develop new drugs. Clinical trials have also become extremely globalized in the past 15 years, with over 225,000 international trials ongoing at this point in time. Principles in Practice of Clinical Trials is truly an interdisciplinary that will be divided into the following areas: 1) Clinical Trials Basic Perspectives 2) Regulation and Oversight 3) Basic Trial Designs 4) Advanced Trial Designs 5) Analysis 6) Trial Publication 7) Topics Related Specific Populations and Legal Aspects of Clinical Trials The Work is designed to be comprised of 175 chapters and approximately 2500 pages. The Work will be oriented like many of our SpringerReference Handbooks, presenting detailed and comprehensive expository chapters on broad subjects. The Editors are major figures in the field of clinical trials, and both have written textbooks on the topic. There will also be a slate of 7-8 renowned associate editors that will edit individual sections of the Reference.
Book Synopsis Tumor Immunology and Immunotherapy by : Robert C. Rees
Download or read book Tumor Immunology and Immunotherapy written by Robert C. Rees and published by Oxford University Press, USA. This book was released on 2014 with total page 469 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tumor immunology and immunotherapy provides a comprehensive account of cancer immunity and immunotherapy. Examining recent results, current areas of interest and the specific issues that are affecting the research and development of vaccines, this book provides insight into how these problems may be overcome as viewed by leaders in the field.
Book Synopsis Breaking Through by : Francisco Jiménez
Download or read book Breaking Through written by Francisco Jiménez and published by Cambridge University Press. This book was released on 2001 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Publisher Description
