Highly Selective Separations In Biotechnology

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Highly Selective Separations in Biotechnology

Author : G. Street
Publisher : Springer Science & Business Media
ISBN 13 : 940111322X
Total Pages : 242 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis Highly Selective Separations in Biotechnology by : G. Street

Download or read book Highly Selective Separations in Biotechnology written by G. Street and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Success in meeting the challenge to produce the commercial products anticipated by the exploitation of biological processes depends upon provid ing effective separation protocols. Effectiveness can be measured in terms of selectivity, purity, resolution and validatory success. The major processing problems are associated with either the selective recovery of molecules which are present in low concentrations from complex mixtures or the selective removal of contaminants from the desired molecule. Central to the evolution of processes satisfying this demand are the regulatory requirements being imposed by governments on the purity of a product, especially in the health care market. Synthetic organic chemists are increasingly finding it advantageous to conduct one or more steps using either enzymic biotransformations where molecules with a single and consistent stereochemistry or chirality are required. The underlying princi ples behind the methods, techniques and processes currently being used and developed commercially rely upon the biospecific nature and properties of the desired molecule. When these factors are married to the more traditional techniques of precipitation, chromatography, liquid-liquid extraction and membrane processes, powerful tools emerge, allowing highly selective separations to be designed. The logical extension of these combinations is to apply genetic engineering techniques to influence the separations at a more fundamental and structural level by modifying the target protein at source, during its synthesis, to facilitate its separation in a given, selective manner, leading to the distinct possibility of producing 'designer' separation programmes.

Separation Processes

Author : R. A. Betts
Publisher :
ISBN 13 : 9781870669658
Total Pages : 32 pages
Book Rating : 4.6/5 (696 download)

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Book Synopsis Separation Processes by : R. A. Betts

Download or read book Separation Processes written by R. A. Betts and published by . This book was released on 1988 with total page 32 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Separations for Biotechnology 2

Author : D. Leo Pyle
Publisher : Springer Science & Business Media
ISBN 13 : 9400907834
Total Pages : 659 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis Separations for Biotechnology 2 by : D. Leo Pyle

Download or read book Separations for Biotechnology 2 written by D. Leo Pyle and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 659 pages. Available in PDF, EPUB and Kindle. Book excerpt: The challenge of bioseparations is to isolate and purify identified products from the dilute product broth produced from cell culture. Innovation in bioseparations technology is increasingly driven by the requirements imposed by the growing importance of production on a process scale of injectable-grade products, and economic pressures to improve the efficiency of downstream processing. As in other areas of technical change, science does not necessarily precede new technology: progress results from a complex and messy mixture of advances in understanding, ingenious ideas, novel techniques and chance discoveries. What is certain is that close interaction between academics and practitioners, biological scientists and process engineers is needed to solve the problems of bioseparations. The Second International Conference on Separations for Biotechnology at Reading, UK, in September 1990 set out to provide a critical multidisciplinary forum for the discussion of bioseparations. This volume contains the papers presented at the meeting. The meeting was organised around six themes with oral and poster presentations on the science and practice of bioseparations technology, and the same structure has been kept for this book. We have also included the texts of the keynote review paper by Professor Alan Michaels and the introductory review papers specially commissioned for the conference. Within each part of this book the review paper is followed by the contributed papers grouped alphabetically by their first author. All the original papers published here were accepted for publication after scientific refereeing.

Methods for Affinity-Based Separations of Enzymes and Proteins

Author : Munishwar N. Gupta
Publisher : Birkhäuser
ISBN 13 : 3034881274
Total Pages : 234 pages
Book Rating : 4.0/5 (348 download)

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Book Synopsis Methods for Affinity-Based Separations of Enzymes and Proteins by : Munishwar N. Gupta

Download or read book Methods for Affinity-Based Separations of Enzymes and Proteins written by Munishwar N. Gupta and published by Birkhäuser. This book was released on 2013-12-01 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: One major concern of biotechnology is either using enzymes or producing them. Enzyme/protein production is therefore an important starting point for biotechnology. Bioseparation or Downstream Processing constitutes about 40-90% of the total production cost. Driven by economics, highly selective technologies applicable to large-scale processing have emerged during the last decade. These technologies are slowly diffusing to enzymologists who are working on a smaller scale, looking for fast and efficient purification protocols. The affinity-based techniques (including precipitation, two-phase extractions, expanded bed chromatography, perfusion chromatography and monoliths) described in this volume provide current and new cutting-edge methods. Consequently, the book is of main interest to researchers in biochemistry, biochemical engineering and biotechnology, working either in academic or industrial sectors.

Handbook of Membrane Separations

Author : Anil K. Pabby
Publisher : CRC Press
ISBN 13 : 0849395496
Total Pages : 1210 pages
Book Rating : 4.8/5 (493 download)

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Book Synopsis Handbook of Membrane Separations by : Anil K. Pabby

Download or read book Handbook of Membrane Separations written by Anil K. Pabby and published by CRC Press. This book was released on 2008-07-07 with total page 1210 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Membrane Separations: Chemical, Pharmaceutical, and Biotechnological Applications provides detailed information on membrane separation technologies as they have evolved over the past decades. To provide a basic understanding of membrane technology, this book documents the developments dealing with these technologies. It explores chemical, pharmaceutical, food processing and biotechnological applications of membrane processes ranging from selective separation to solvent and material recovery. This text also presents in-depth knowledge of membrane separation mechanisms, transport models, membrane permeability computations, membrane types and modules, as well as membrane reactors.

Separation Processes in the Food and Biotechnology Industries

Author : A S Grandison
Publisher : Woodhead Publishing
ISBN 13 : 9781855732872
Total Pages : 306 pages
Book Rating : 4.7/5 (328 download)

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Book Synopsis Separation Processes in the Food and Biotechnology Industries by : A S Grandison

Download or read book Separation Processes in the Food and Biotechnology Industries written by A S Grandison and published by Woodhead Publishing. This book was released on 1996-01-15 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews methods and techniques for separating food components and products of the biotechnology industry. The introduction focuses on food composition and some of the conventional separation techniques. Subsequent chapters deal with each specific type or area of application individually and include information on the basic principles, industrial equipment available, commercial applications and an overview of research and development.

Separations Technology

Author : Wayne P. Olson
Publisher : CRC Press
ISBN 13 : 1000717224
Total Pages : 526 pages
Book Rating : 4.0/5 (7 download)

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Book Synopsis Separations Technology by : Wayne P. Olson

Download or read book Separations Technology written by Wayne P. Olson and published by CRC Press. This book was released on 2020-02-03 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: Authored by a team of respected scientists and technologists, this book covers many pharmaceutical and biotechnology separations methods currently in use. Practical applications and descriptions are offered for air elutriation, microporous filtration, ultrafiltration, phase partitioning, crystallization, and chromatographic technologies such as adsorption, affinity, chelate, ion-exchange, size-exclusion, template, hydrophobic interaction, biotransformations, and chiral separations. Containing hundreds of references and a complete index, this book is designed for research and development scientists, process optimization engineers, and quality control laboratory scientists as well as quality assurance professionals and others needing to understand current separation techniques.

Separation Processes in Biotechnology

Author : Juan A. Asenjo
Publisher : CRC Press
ISBN 13 : 100010432X
Total Pages : 824 pages
Book Rating : 4.0/5 (1 download)

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Book Synopsis Separation Processes in Biotechnology by : Juan A. Asenjo

Download or read book Separation Processes in Biotechnology written by Juan A. Asenjo and published by CRC Press. This book was released on 2020-08-26 with total page 824 pages. Available in PDF, EPUB and Kindle. Book excerpt: Edited to avoid duplication and favor comprehensiveness, 20 contributors detail the recovery, separation, and purification operations of bioprocess technology. Individual chapters in this classic yet still highly relevant work emphasize concepts that are becoming more and more important when applied to the large scale versions of techniques that are considered well established. Aside from fully discussing processes, Separation Processes in Biotechnology includes sections on concentration separation and operation, purification operations, and product release and recovery. It also discusses plant operation and equipment and delves into economic considerations

Separations for Biotechnology

Author :
Publisher :
ISBN 13 :
Total Pages : 680 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Separations for Biotechnology by :

Download or read book Separations for Biotechnology written by and published by . This book was released on 1990 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Separations for Biotechnology

Author : M. S. Verrall
Publisher :
ISBN 13 :
Total Pages : 512 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Separations for Biotechnology by : M. S. Verrall

Download or read book Separations for Biotechnology written by M. S. Verrall and published by . This book was released on 1987 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Separations Chemistry

Author : Fedor Macášek
Publisher : Xlibris Corporation
ISBN 13 : 1514417308
Total Pages : 390 pages
Book Rating : 4.5/5 (144 download)

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Book Synopsis Separations Chemistry by : Fedor Macášek

Download or read book Separations Chemistry written by Fedor Macášek and published by Xlibris Corporation. This book was released on 2016-06-06 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: Separation of chemical species is a gate to final success of synthesis and preparation of compounds in pure and defined state. Variability of natural and artificial mixtures to be treated is enormous. Task of chemistry is to separate components of homogeneous mixtures (the gaseous and liquid solutions). The book concentrates on understanding the basic philosophies of both equilibrium and nonequilibrium chemical thermodynamics and engineering performance that lay in principle of separation technique such as distillation, crystallization, centrifugation, sorption, membrane separations, chromatography, and liquid-liquid extraction. Specific phenomena connected with photochemical separation, isotope composition, and radioactivity are discussed as well. The book is written for advanced students of chemistry having the knowledge of physical chemistry. Calculation examples are based on the international system of units. Unique list of over 1,300 full references covers scientific literature of the eighteenth to the twenty-first centuries.

Natural-Based Polymers for Biomedical Applications

Author : Rui L. Reis
Publisher : Elsevier
ISBN 13 : 1845694813
Total Pages : 829 pages
Book Rating : 4.8/5 (456 download)

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Book Synopsis Natural-Based Polymers for Biomedical Applications by : Rui L. Reis

Download or read book Natural-Based Polymers for Biomedical Applications written by Rui L. Reis and published by Elsevier. This book was released on 2008-08-15 with total page 829 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polymers from natural sources are particularly useful as biomaterials and in regenerative medicine, given their similarity to the extracellular matrix and other polymers in the human body. This important book reviews the wealth of research on both tried and promising new natural-based biomedical polymers, together with their applications as implantable biomaterials, controlled-release carriers or scaffolds for tissue engineering.The first part of the book reviews the sources, processing and properties of natural-based polymers for biomedical applications. Part two describes how the surfaces of polymer-based biomaterials can be modified to improve their functionality. The third part of the book discusses the use of natural-based polymers for biodegradable scaffolds and hydrogels in tissue engineering. Building on this foundation, Part four looks at the particular use of natural-gelling polymers for encapsulation, tissue engineering and regenerative medicine. The penultimate group of chapters reviews the use of natural-based polymers as delivery systems for drugs, hormones, enzymes and growth factors. The final part of the book summarises research on the key issue of biocompatibility.Natural-based polymers for biomedical applications is a standard reference for biomedical engineers, those studying and researching in this important area, and the medical community. - Examines the sources, processing and properties of natural based polymers for biomedical applications - Explains how the surfaces of polymer based biomaterials can be modified to improve their functionality - Discusses the use of natural based polymers for hydrogels in tissue engineering, and in particular natural gelling polymers for encapsulation and regenerative medicine

Centrifugal Separations in Biotechnology

Author : Wallace Woon-Fong Leung
Publisher : Butterworth-Heinemann
ISBN 13 : 0081026358
Total Pages : 503 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Centrifugal Separations in Biotechnology by : Wallace Woon-Fong Leung

Download or read book Centrifugal Separations in Biotechnology written by Wallace Woon-Fong Leung and published by Butterworth-Heinemann. This book was released on 2020-03-13 with total page 503 pages. Available in PDF, EPUB and Kindle. Book excerpt: Centrifugal Separations in Biotechnology, Second Edition, is the only book on the market devoted to centrifugal separation in biotechnology. Key topics covered include a full introduction to centrifugation, sedimentation and separation; detailed coverage of centrifuge types, including batch and semi-batch centrifuges, disk-stack and tubular decanter centrifuges; methods for increasing solids concentration; laboratory and pilot testing of centrifuges; selection and sizing centrifuges; scale-up of equipment, performance prediction and analysis of test results using numerical simulation. Centrifugal Separations in Biotechnology, Second Edition, provides guidance on troubleshooting and optimizing centrifuges, and then goes on to explore the commercial applications of centrifuges in biotechnology. It gives detailed process information and data to assist in the development of particular processes from existing systems. It is of value to professionals in the chemical, bioprocess, and biotech sectors, and all those concerned with bioseparation, bioprocessing, unit-operations and process engineering. Provides a comprehensive guide to centrifuges, their optimal development, and their operation in the biotechnology industry Updated throughout based on developments in industrial applications and advances in our understanding of centrifugal separations in biotechnology Discusses applications for the separation of proteins, DNA, mitochondria, ribosomes, lysosomes and other cellular elements Includes new sections on use of optimal polymer dosage in waste treatment, new centrifuge designs for applications in algae processing, biopharma, and more

Smart Polymers and their Applications

Author : Maria Rosa Aguilar
Publisher : Elsevier
ISBN 13 : 0857097024
Total Pages : 587 pages
Book Rating : 4.8/5 (57 download)

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Book Synopsis Smart Polymers and their Applications by : Maria Rosa Aguilar

Download or read book Smart Polymers and their Applications written by Maria Rosa Aguilar and published by Elsevier. This book was released on 2014-02-19 with total page 587 pages. Available in PDF, EPUB and Kindle. Book excerpt: Smart polymers are polymers that respond to different stimuli or changes in the environment. Smart Polymers and their Applications reviews the types, synthesis, properties, and applications of smart polymers. Chapters in part one focus on types of polymers, including temperature-, pH-, photo-, and enzyme-responsive polymers. Shape memory polymers, smart polymer hydrogels, and self-healing polymer systems are also explored. Part two highlights applications of smart polymers, including smart instructive polymer substrates for tissue engineering; smart polymer nanocarriers for drug delivery; the use of smart polymers in medical devices for minimally invasive surgery, diagnosis, and other applications; and smart polymers for bioseparation and other biotechnology applications. Further chapters discuss the use of smart polymers for textile and packaging applications, and for optical data storage. Smart Polymers and their Applications is a technical resource for chemists, chemical engineers, mechanical engineers, and other professionals in the polymer industry; manufacturers in such sectors as medical, automotive, and aerospace engineering; and academic researchers in polymer science. - Reviews the different types of smart polymer, discussing their properties, structure, design, and characterization - Reviews applications of smart polymers in such areas as biomedical engineering, textiles, and food packaging

Industrial Membrane Separation Technology

Author : K. Scott
Publisher : Springer Science & Business Media
ISBN 13 : 9780751403381
Total Pages : 326 pages
Book Rating : 4.4/5 (33 download)

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Book Synopsis Industrial Membrane Separation Technology by : K. Scott

Download or read book Industrial Membrane Separation Technology written by K. Scott and published by Springer Science & Business Media. This book was released on 1996 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although membrane separations can now routinely replace traditional separations, there is a need for the new developments in the applications and theories of membrane separation to be transmitted to industry to continue the drive forward in membrane development. This book presents new developments in the context of industrial technology and relates the principles of design to plant set-up and equipment selection.

Separation processes

Author : Richard A. Betts
Publisher :
ISBN 13 :
Total Pages : 32 pages
Book Rating : 4.:/5 (916 download)

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Book Synopsis Separation processes by : Richard A. Betts

Download or read book Separation processes written by Richard A. Betts and published by . This book was released on 1988 with total page 32 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Isolation and Purification of Proteins

Author : Rajni Hatti-Kaul
Publisher : CRC Press
ISBN 13 : 9780203911686
Total Pages : 688 pages
Book Rating : 4.9/5 (116 download)

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Book Synopsis Isolation and Purification of Proteins by : Rajni Hatti-Kaul

Download or read book Isolation and Purification of Proteins written by Rajni Hatti-Kaul and published by CRC Press. This book was released on 2003-02-05 with total page 688 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication details the isolation of proteins from biological materials, techniques for solid-liquid separation, concentration, crystallization, chromatography, scale-up, process monitoring, product formulation, and regulatory and commercial considerations in protein production. The authors discuss the release of protein from a biological host, selectivity in affinity chromatography, precipitation of proteins (both non-specific and specific), extraction for rapid protein isolation, adsorption as an initial step for the capture of proteins, scale-up and commercial production of recombinant proteins, and process monitoring in downstream processing.