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Author : Martin Schick
Publisher :
ISBN 13 : 9783896493644
Total Pages : 223 pages
Book Rating : 4.4/5 (936 download)
Download or read book High Pressure NMR of Ubiquitin written by Martin Schick and published by . This book was released on 1998 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Jiri Jonas
Publisher : Springer Science & Business Media
ISBN 13 : 3642759262
Total Pages : 272 pages
Book Rating : 4.6/5 (427 download)
Download or read book High Pressure NMR written by Jiri Jonas and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, there has been a major expansion of high pressure research providing unique information about systems of interest to a wide range of scientific disciplines. Since nuclear magnetic resonance has been applied to a wide spec trum of problems in chemistry, physics and biochemistry, it is not surprising to find that high pressure NMR techniques have also had many applications in these fields of science. Clearly, the high information content of NMR experiments combined with high pressure provides a powerful tool in modern chem istry. It is the aim of this monograph, in the series on NMR Basic Principles and Progress, to illustrate the wide range of prob lems which can be successfully studied by high pressure NMR. Indeed, the various contributions in this volume discuss studies of interest to physics, chemical physics, biochemistry, and chemical reaction kinetics. In many different ways, this monograph demonstrates the power of modern experimental and theoretical techniques to investigate very complex systems. The first contribution, by D. Brinkman, deals with NMR and NQR studies of superionic conductors and high-Tc supercon ductors at high pressure. Pressure effects on phase transitions, detection of new phases, and pressure effects on diffusion and spin-lattice relaxation, represent a few of the topics discussed in this contribution of particular interest to solid state physics.
Author : Kazuyuki Akasaka
Publisher : Springer
ISBN 13 : 9401799180
Total Pages : 722 pages
Book Rating : 4.4/5 (17 download)
Download or read book High Pressure Bioscience written by Kazuyuki Akasaka and published by Springer. This book was released on 2015-07-14 with total page 722 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume covers both the basic concepts and theory of bio-macromolecules under pressure and the various frontiers in high-pressure bioscience and biotechnology. A century has passed since Bridgman discovered the irreversible coagulation of egg white by applying pressure at 700 atmospheres in 1914. Today we are able to monitor pressure-dependent changes in protein structure as a reversible process even at atomic scale with modern spectroscopic techniques. We can study the fluctuating reality of protein structures as designed by nature, which is the basis for all dynamism of life on earth. We are currently facing a new era of high-pressure bioscience, in which pressure is no longer an “odd” or “foreign” variable to life, but rather an integrated part of it. Pressure is used as a crucial variable for disclosing the secrets of nature and as a powerful new tool for enhancing certain reactions in bio-macromolecules and even in living cells for our practical and industrial needs. A dramatic advancement of high-pressure bioscience both in the basic and the applied sciences is thus anticipated in near future, for which sharing the current advanced knowledge on structure and dynamics of bio-macromolecules under pressure among researchers in both fields is crucial. This book serves as a valuable resource not only for those working directly in a pressure-related field, but also for those working in many other fields of the biosciences. Particularly, the basic part of it is intended to serve as a classical text book on high-pressure bioscience to a wide audience including students and researchers in both basic and applied fields in years to come. Readers can focus on topics of immediate interest first, but may wish to go over other chapters if interest arises in a later occasion.
Author : The Nuclear Magnetic Resonance Society of Japan
Publisher : Springer
ISBN 13 : 9811059667
Total Pages : 634 pages
Book Rating : 4.8/5 (11 download)
Download or read book Experimental Approaches of NMR Spectroscopy written by The Nuclear Magnetic Resonance Society of Japan and published by Springer. This book was released on 2017-11-23 with total page 634 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the advanced developments in methodology and applications of NMR spectroscopy to life science and materials science. Experts who are leaders in the development of new methods and applications of life and material sciences have contributed an exciting range of topics that cover recent advances in structural determination of biological and material molecules, dynamic aspects of biological and material molecules, and development of novel NMR techniques, including resolution and sensitivity enhancement. First, this book particularly emphasizes the experimental details for new researchers to use NMR spectroscopy and pick up the potentials of NMR spectroscopy. Second, the book is designed for those who are involved in either developing the technique or expanding the NMR application fields by applying them to specific samples. Third, the Nuclear Magnetic Resonance Society of Japan has organized this book not only for NMR members of Japan but also for readers worldwide who are interested in using NMR spectroscopy extensively.
Author : Eric Charles Johnson
Publisher :
ISBN 13 :
Total Pages : 312 pages
Book Rating : 4.:/5 (34 download)
Download or read book NMR Structures and Dynamics of Designed Hydrophobic Core Variants of Ubiquitin written by Eric Charles Johnson and published by . This book was released on 1999 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : European High Pressure Research Group. Meeting
Publisher : James Currey
ISBN 13 :
Total Pages : 564 pages
Book Rating : 4.3/5 (91 download)
Download or read book High Pressure Research in the Biosciences and Biotechnology written by European High Pressure Research Group. Meeting and published by James Currey. This book was released on 1997 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Marilisa Leone
Publisher : Mdpi AG
ISBN 13 : 9783036523521
Total Pages : 248 pages
Book Rating : 4.5/5 (235 download)
Download or read book The Conformational Universe of Proteins and Peptides written by Marilisa Leone and published by Mdpi AG. This book was released on 2021-11-25 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proteins represent one of the most abundant classes of biological macromolecules and play crucial roles in a vast array of physiological and pathological processes. The knowledge of the 3D structure of a protein, as well as the possible conformational transitions occurring upon interaction with diverse ligands, are essential to fully comprehend its biological function. In addition to globular, well-folded proteins, over the past few years, intrinsically disordered proteins (IDPs) have received a lot of attention. IDPs are usually aggregationprone and may form toxic amyloid fibers and oligomers associated with several human pathologies. Peptides are smaller in size than proteins but similarly represent key elements of cells. A few peptides are able to work as tumor markers and find applications in the diagnostic and therapeutic fields. The conformational analysis of bioactive peptides is important to design novel potential drugs acting as selective modulators of specific receptors or enzymes. Nevertheless, synthetic peptides reproducing different protein fragments have frequently been implemented as model systems in folding studies relying on structural investigations in water and/or other environments. This book contains contributions (seven original research articles and five reviews published in the journal Molecules) on the above-described topics and, in detail, it includes structural studies on globular folded proteins, IDPs and bioactive peptides. These works were conducted usingdifferent experimental methods.
Author : Murli H. Manghnani
Publisher : Universities Press
ISBN 13 : 9788173713385
Total Pages : 650 pages
Book Rating : 4.7/5 (133 download)
Download or read book Science and Technology of High Pressure written by Murli H. Manghnani and published by Universities Press. This book was released on 2000 with total page 650 pages. Available in PDF, EPUB and Kindle. Book excerpt: These books presents a wide spectrum of research and development activities in the field of High Pressure Science and Technology. These book provide comprehensive and interdisciplinary descriptions of recent research accomplishments in the biological, chemical, Earth, materrals, physical, physiological and related sciences.
Author : Raymond Joseph Deshaies
Publisher : Gulf Professional Publishing
ISBN 13 : 9780121828042
Total Pages : 996 pages
Book Rating : 4.8/5 (28 download)
Download or read book Ubiquitin and Protein Degradation written by Raymond Joseph Deshaies and published by Gulf Professional Publishing. This book was released on 2005 with total page 996 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ubiquitin and Protein Degradation, Part B will cover chemical biology, ubiquitin derivatives and ubiquitin-like proteins, deubiquitinating enzymes, proteomics as well as techniques to monitor protein degradation. The chapters are highly methodological and focus on application of techniques. *Second part of the Ubiquitin and Protein Degration series *Topics include: E1 Enzymes, E2 Enzymes, E3 Enzymes, Proteasomes, and Isopeptidases.
Author : M. Rechsteiner
Publisher : Springer Science & Business Media
ISBN 13 : 1489920498
Total Pages : 358 pages
Book Rating : 4.4/5 (899 download)
Download or read book Ubiquitin written by M. Rechsteiner and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Roland Winter
Publisher : Springer Science & Business Media
ISBN 13 : 3662056135
Total Pages : 472 pages
Book Rating : 4.6/5 (62 download)
Download or read book Advances in High Pressure Bioscience and Biotechnology II written by Roland Winter and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: With original work on marine and terrestrial microbiology, biochemistry, molecular biology, deep-sea diving, food science, and other industrial applications, this book covers the whole range of current high pressure bioscience. It will be welcomed by all industrial and academic researchers working in this field.
Author : Mazahide Terazima
Publisher : Springer
ISBN 13 : 4431558403
Total Pages : 276 pages
Book Rating : 4.4/5 (315 download)
Download or read book Molecular Science of Fluctuations Toward Biological Functions written by Mazahide Terazima and published by Springer. This book was released on 2016-02-09 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this monograph, the importance of fluctuations for biological reactions is discussed from various points of view. Understanding the biological reactions at the molecular level is one of the major targets in many scientific fields, including not only basic biology but also physics, physical chemistry, and medical science. One of the key factors in the process is “fluctuation”. Thermal energy causes biological molecules to be in constant fluctuation even while they are carrying out their biological functions. How do biological systems overcome the thermal fluctuations to realize the physiologically relevant reactions? Scientists in a number of fields—physics, chemistry, pharmacology, medicine, and others—have contributed chapters that elucidate the nature of the fluctuations and the relationship between fluctuations and biological functions. The fluctuations discussed in this volume are detected by the transient grating method, nuclear magnetic resonance, X-ray diffraction and scattering, and computer simulation, among other methods. The book presents various results of the studies of fluctuations in biological processes that were obtained with these methods by the leading scientists in their fields.
Author : Jan-Michael Peters
Publisher : Springer Science & Business Media
ISBN 13 : 0306456494
Total Pages : 498 pages
Book Rating : 4.3/5 (64 download)
Download or read book Ubiquitin and the Biology of the Cell written by Jan-Michael Peters and published by Springer Science & Business Media. This book was released on 1998-05-31 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: The last several years have been a landmark period in the ubiquitin field. The breadth of ubiquitin's roles in cell biology was first sketched, and the importance of ubiquitin-dependent proteolysis as a regulatory mechanism gained general acceptance. The many strands of work that led to this new perception are re counted in this book. A consequence of this progress is that the field has grown dramatically since the first book on ubiquitin was published almost a decade ago [M. Rechsteiner (ed. ), Ubiquitin, Plenum Press, 1988]. In this span, students of the cell cycle, transcription, signal transduction, protein sorting, neuropathology, cancer, virology, and immunology have attempted to chart the role of ubi quit in in their particular experimental systems, and this integration of the field into cell biology as a whole continues at a remarkable pace. We hope that for active researchers in the field as well as for newcomers and those on the fence, this book will prove helpful for its breadth, historical perspective, and practical tips. Structural data are now available on many of the components of the ubiquitin pathway. The structures have provided basic insights into the unusual biochemical mechanisms of ubiquitination and proteasome-mediated proteolysis. Because high-speed computer graphics can convey structures more effectively than print media, we have supplemented the figures of the book with a Worldwide Web site that can display the structures in a flexible, viewer-controlled format.
Author : Claude Balny
Publisher : Elsevier
ISBN 13 : 9780444510990
Total Pages : 414 pages
Book Rating : 4.5/5 (19 download)
Download or read book Frontiers in High Pressure Biochemistry and Biophysics written by Claude Balny and published by Elsevier. This book was released on 2002-06-05 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first book covering all aspects of high pressure biochemistry and biophysics of proteins. Hydrostatic pressure is a powerful tool for study of biological systems. As a thermodynamic parameter, hydrostatic pressure has been known for a century to act on biological materials in a similar, but not identical, way to temperature. However, pressure was disregarded for a long time by biochemists mainly because the basic concepts (and the thermodynamics) focused on the chemical reactions involved and because general ideas on what pressure can add to the understanding of the behaviour of proteins were lacking. In recent decades, technological progress in the field of physics has shown, along with parameters such as temperature and solvent conditions, that pressure can be used for more refined thermodynamic and kinetic descriptions of biological processes and regulation of biological systems. The effects of pressure on proteins, nucleoproteins and membranes have recently been reviewed and several proceedings books have been published.
Author : Anirban Bhunia
Publisher : Royal Society of Chemistry
ISBN 13 : 1839165715
Total Pages : 733 pages
Book Rating : 4.8/5 (391 download)
Download or read book NMR Spectroscopy for Probing Functional Dynamics at Biological Interfaces written by Anirban Bhunia and published by Royal Society of Chemistry. This book was released on 2022-08-17 with total page 733 pages. Available in PDF, EPUB and Kindle. Book excerpt: NMR spectroscopy has found a wide range of applications in life sciences over recent decades. Providing a comprehensive amalgamation of the scattered knowledge of how to apply high-resolution NMR techniques to biomolecular systems, this book will break down the conventional stereotypes in the use of NMR for structural studies. The major focus is on novel approaches in NMR which deal with the functional interface of either protein-protein interactions or protein-lipid interactions. Bridging the gaps between structural and functional studies, the Editors believe a thorough compilation of these studies will open an entirely new dimension of understanding of crucial functional motifs. This in turn will be helpful for future applications into drug design or better understanding of systems. The book will appeal to NMR practitioners in industry and academia who are looking for a comprehensive understanding of the possibilities of applying high-resolution NMR spectroscopic techniques in probing biomolecular interactions.
Author : Graham A. Webb
Publisher : Elsevier
ISBN 13 : 0080551947
Total Pages : 237 pages
Book Rating : 4.0/5 (85 download)
Download or read book Annual Reports on NMR Spectroscopy written by Graham A. Webb and published by Elsevier. This book was released on 2007-10-11 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nuclear magnetic resonance (NMR) is an analytical tool used by chemists and physicists to study the structure and dynamics of molecules. In recent years, no other technique has grown to such importance as NMR spectroscopy. It is used in all branches of science when precise structural determination is required and when the nature of interactions and reactions in solution is being studied. Annual Reports on NMR Spectroscopy has established itself as a premier means for the specialist and nonspecialist alike to become familiar with new techniques and applications of NMR spectroscopy. - Provides updates on the latest developments in NMR spectroscopy - Includes comprehensive review articles - Highlights the increasing importance of NMR spectroscopy as a technique for structural determination
Author : R. Winter
Publisher : Springer Science & Business Media
ISBN 13 : 9401146691
Total Pages : 551 pages
Book Rating : 4.4/5 (11 download)
Download or read book High Pressure Molecular Science written by R. Winter and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 551 pages. Available in PDF, EPUB and Kindle. Book excerpt: For chemists, biochemists, physicists and materials scientists, pressure as an experimental variable represents a tool that provides unique information about the microscopic properties of the materials being studied. In addition to its use as a research tool for investigating the energetics, structure, dynamics and kinetics of molecular transformations of materials, pressure is also being used to modify the properties of materials to preserve or improve their properties. The contributions collected here cover the main areas of high pressure research, including applications in materials science, condensed matter physics, chemistry and biochemistry. In addition, some papers offer more specialised aspects of high pressure studies. The book makes clear the impressive range of fundamental and applied problems that can be studied by high pressure techniques and also points towards a major growth of high pressure science and technology in the near future.
