˜High performanceœ [High-performance] liquid chromatography in the clinical laboratory

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Publisher :
ISBN 13 :
Total Pages : 161 pages
Book Rating : 4.:/5 (16 download)

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Book Synopsis ˜High performanceœ [High-performance] liquid chromatography in the clinical laboratory by : Danny C. Sampson

Download or read book ˜High performanceœ [High-performance] liquid chromatography in the clinical laboratory written by Danny C. Sampson and published by . This book was released on 1986 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt:

High Performance Liquid Chromatography in the Clinical Laboratory

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Author :
Publisher :
ISBN 13 : 9780731617241
Total Pages : 161 pages
Book Rating : 4.6/5 (172 download)

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Book Synopsis High Performance Liquid Chromatography in the Clinical Laboratory by : Danny C. Sampson

Download or read book High Performance Liquid Chromatography in the Clinical Laboratory written by Danny C. Sampson and published by . This book was released on 1986 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt:

New Developments in Clinical Instrumentation

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Publisher : CRC Press
ISBN 13 : 1351091875
Total Pages : 294 pages
Book Rating : 4.3/5 (51 download)

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Book Synopsis New Developments in Clinical Instrumentation by : Leroy Hersh

Download or read book New Developments in Clinical Instrumentation written by Leroy Hersh and published by CRC Press. This book was released on 2018-01-18 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book has information regarding the new developments in clinical instrumentation, focusing on fluorometers and densitometers, explaining the principles, the use of high performance liquid chromatography in clinical laboratories. Automated Microbiology; dabbling into detection, light scanning and analysis of particles. Amore recent aspect of automation has been, made possible by the advent of the microprocessor orcomputer-on-a-chip. The development of miniature, inexpensive micro-computers has resulted in the automation for relatively sophisticated processes. The two aspects of automation are represented in this monograph. The automated control of physical processes, and automation of the information processing. There are elements of both aspects of automation in this book. The areas discussed do emphasize more or less strongly either tight automated control of physical processes or automation of information processing. They all represent the attempt of medical technology to yield more precise, accurate, less expensive and faster to acid in the clinical diagnosis.

Practice of High Performance Liquid Chromatography

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642692257
Total Pages : 468 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Practice of High Performance Liquid Chromatography by : Heinz Engelhardt

Download or read book Practice of High Performance Liquid Chromatography written by Heinz Engelhardt and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: During its short 20 year history High Performance Liquid Chro matography (HPLC) has won itself a firm place amongst the instrumental methods of analysis. HPLC has caused a revolution in biological and pharmaceutical chemistry. Approximately two thirds of the publications on HPLC are concerned with problems from this area of life science. Biotechnology, where it is necessary to isolate substances from complicated mixtures, is likely to give further impetus to the dissemination of modern liquid chromatog raphy in columns, particularly on the preparative scale. This book presents, by means of examples, the application of HPLC to various fields, as well as fundamental discussions of chromatographic methods. The quality of the analytical result is decisively dependent on the qualities of the equipment employed (by Colin, Guiochon, and Martin). Especially the demands are discussed that are placed on the components of the instrument including those for data acquisition and processing. The section on "quantitative analy sis" (by ABhauer, Ullner) covers besides the principles also the problems of ensuring the quality of the data in detail. The basic problems arising by enlarging the sample size to preparative di mensions and the requirements put on the aparatus are discussed in the section on "preparative applications" (by Wehrli).

Chromatographic Methods in Clinical Chemistry and Toxicology

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Publisher : John Wiley & Sons
ISBN 13 : 0470023104
Total Pages : 308 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Chromatographic Methods in Clinical Chemistry and Toxicology by : Roger Bertholf

Download or read book Chromatographic Methods in Clinical Chemistry and Toxicology written by Roger Bertholf and published by John Wiley & Sons. This book was released on 2007-01-30 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to fill the gap that exists between theoretical treatments of chromatography, and clinical chemistry and toxicology texts, which focus almost exclusively on clinical relevance and applications. Chromatography has a vast array of clinical applications, and though the chromatographic methods were first introduced decades ago, new applications of this technology are being used to explore previously inaccessible frontiers in clinical diagnostics and toxicological testing. An up-to-date book devoted to clinical and toxicological applications of chromatographic methods will serve as an instructional and reference text, useful to students, laboratory technicians, and researchers.

High Performance Liquid Chromatography

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Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 3110528959
Total Pages : 501 pages
Book Rating : 4.1/5 (15 download)

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Book Synopsis High Performance Liquid Chromatography by : Omar Al Sayed Omar

Download or read book High Performance Liquid Chromatography written by Omar Al Sayed Omar and published by Walter de Gruyter GmbH & Co KG. This book was released on 2022-02-21 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the past decade, modern high-performance liquid chromatography (HPLC) utilization has expanded greatly, especially in the quality control of pharmaceutical products in drug quality control laboratories. This book provides an extensive collection of technical information about HPLC-Columns (physicochemical properties and chromatographic characteristics), from various manufacturers, and helps analysts to decide on the ideal approach for their analysis according to the requirements of drug manufacturers specifi cations and the desired Pharmacopeia. In addition, the authors give practical advice on how to prepare mobile phases, choose a suitable detector, and set up an HPLC analysis. This book is comprehensive for the average professional or technician who plans to work with modern HPLC. This book is useful for most Drug Quality Control Laboratories where modern HPLC is utilized. Following a hands-on approach, the book gives key insights into the pharmaceutical applications of HPLC and the latest requirements of the major regulatory agencies such as ICH, FDA, or USP.

HPLC in the Pharmaceutical Industry

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Publisher : CRC Press
ISBN 13 : 1000104613
Total Pages : 321 pages
Book Rating : 4.0/5 (1 download)

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Book Synopsis HPLC in the Pharmaceutical Industry by : Godwin W. Fong

Download or read book HPLC in the Pharmaceutical Industry written by Godwin W. Fong and published by CRC Press. This book was released on 2022-01-26 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: A practical guide for chemists in the pharmaceutical industry to making automated analyses of drugs that will meet the standards of regulatory agencies. Reviews the standard techniques of high-performance liquid chromatography, specialized detection methods, automation in pharmaceutical analysis, analyses of pharmaceuticals- helping readers meet rigorous regulatory agency standards for acceptable test results. Written by leading experts in the field, this text describes current liquid chromatographic techniques in pharamaceutical analysis...discusses highly sensitve detailed detection of drugs... considers automatation in pharamaceutical analysis...examines new molecular entities and opitcal isomers... and more.

Analytical Techniques for Clinical Chemistry

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Publisher : John Wiley & Sons
ISBN 13 : 111827184X
Total Pages : 37 pages
Book Rating : 4.1/5 (182 download)

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Book Synopsis Analytical Techniques for Clinical Chemistry by : Sergio Caroli

Download or read book Analytical Techniques for Clinical Chemistry written by Sergio Caroli and published by John Wiley & Sons. This book was released on 2012-06-26 with total page 37 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discover how analytical chemistry supports the latest clinical research This book details the role played by analytical chemistry in fostering clinical research. Readers will discover how a broad range of analytical techniques support all phases of clinical research, from early stages to the implementation of practical applications. Moreover, the contributing authors' careful step-by-step guidance enables readers to better understand standardized techniques and steer clear of everyday problems that can arise in the lab. Analytical Techniques for Clinical Chemistry opens with an overview of the legal and regulatory framework governing clinical lab analysis. Next, it details the latest progress in instrumentation and applications in such fields as biomonitoring, diagnostics, food quality, biomarkers, pharmaceuticals, and forensics. Comprised of twenty-five chapters divided into three sections exploring Fundamentals, Selected Applications, and Future Trends, the book covers such critical topics as: Uncertainty in clinical chemistry measurements Metal toxicology in clinical, forensic, and chemical pathology Role of analytical chemistry in the safety of drug therapy Atomic spectrometric techniques for the analysis of clinical samples Biosensors for drug analysis Use of X-ray techniques in medical research Each chapter is written by one or more leading pioneers and experts in analytical chemistry. Contributions are based on a thorough review and analysis of the current literature as well as the authors' own firsthand experiences in the lab. References at the end of each chapter serve as a gateway to the literature, enabling readers to explore individual topics in greater depth. Presenting the latest achievements and challenges in the field, Analytical Techniques for Clinical Chemistry sets the foundation for future advances in laboratory research techniques.

Mass Spectrometry for the Clinical Laboratory

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Publisher : Academic Press
ISBN 13 : 0128009926
Total Pages : 306 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Mass Spectrometry for the Clinical Laboratory by : Hari Nair

Download or read book Mass Spectrometry for the Clinical Laboratory written by Hari Nair and published by Academic Press. This book was released on 2016-11-02 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mass Spectrometry for the Clinical Laboratory is an accessible guide to mass spectrometry and the development, validation, and implementation of the most common assays seen in clinical labs. It provides readers with practical examples for assay development, and experimental design for validation to meet CLIA requirements, appropriate interference testing, measuring, validation of ion suppression/matrix effects, and quality control. These tools offer guidance on what type of instrumentation is optimal for each assay, what options are available, and the pros and cons of each. Readers will find a full set of tools that are either directly related to the assay they want to adopt or for an analogous assay they could use as an example. Written by expert users of the most common assays found in a clinical laboratory (clinical chemists, toxicologists, and clinical pathologists practicing mass spectrometry), the book lays out how experts in the field have chosen their mass spectrometers, purchased, installed, validated, and brought them on line for routine testing. The early chapters of the book covers what the practitioners have learned from years of experience, the challenges they have faced, and their recommendations on how to build and validate assays to avoid problems. These chapters also include recommendations for maintaining continuity of quality in testing. The later parts of the book focuses on specific types of assays (therapeutic drugs, Vitamin D, hormones, etc.). Each chapter in this section has been written by an expert practitioner of an assay that is currently running in his or her clinical lab. Provides readers with the keys to choosing, installing, and validating a mass spectrometry platform Offers tools to evaluate, validate, and troubleshoot the most common assays seen in clinical pathology labs Explains validation, ion suppression, interference testing, and quality control design to the detail that is required for implementation in the lab

Therapeutic Drug Monitoring and Toxicology by Liquid Chromatography

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Author :
Publisher : Routledge
ISBN 13 : 135140847X
Total Pages : 521 pages
Book Rating : 4.3/5 (514 download)

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Book Synopsis Therapeutic Drug Monitoring and Toxicology by Liquid Chromatography by : Steven H.Y. Wong

Download or read book Therapeutic Drug Monitoring and Toxicology by Liquid Chromatography written by Steven H.Y. Wong and published by Routledge. This book was released on 2017-09-19 with total page 521 pages. Available in PDF, EPUB and Kindle. Book excerpt: This important, new reference provides the first , up-to-date, and comprehensive treatmentof the various liquid chromatography (LC) instrumentation for Therapeutic DrugMonitoring (TDM) and toxicology drug assays and reviews the clinical pharmacologyof major classes of drugs and their LC analyses.Written by authoritative contributors who bring many years of personal laboratory/clinical experience to the book, this interdisciplinary work : presents the principlesof TDM, sampling techniques, and various instrumentation topics, including computerinterfacing, mass spectrometry, fluorescence , electrochemical detection, and bloodcollection devices . .. examines six primary classes of drugs, complete with recommendedLC procedures and emphasizing recently introduced drugs and their LC analyses. .. and documents medicolegal guidelines and laboratory management considerations,providing a contemporary assessment of today's laboratory needs.The only practical, current guide available on the subject, Therapeutic Drug Monitoringand Toxicology by Li([uid Chromatography belongs in the personal libraries of clinicaland analytical chemists and biochemists, clinical pharmacologists, clinical toxicologists,clinical pathologists, immunologists, liquid chromatographers, mass spectroscopists, laboratorydirectors, laboratory instrument manufacturers , and medical technologists. Thebook is also vital supplementary reading for advanced undergraduate and graduate-levelclinical chemistry, toxicology, clinical pathology, and liquid chromatography course.

The HPLC-MS Handbook for Practitioners

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Publisher : John Wiley & Sons
ISBN 13 : 3527343075
Total Pages : 249 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis The HPLC-MS Handbook for Practitioners by : Stavros Kromidas

Download or read book The HPLC-MS Handbook for Practitioners written by Stavros Kromidas and published by John Wiley & Sons. This book was released on 2017-10-16 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dieses prägnante, kompakte und übersichtliche Fachbuch befasst sich ausschließlich mit den praktischen Aspekten der HPLC-MS-Kopplung und vermittelt detailliert die Kenntnisse, um diese Methode effizient einsetzen zu können. Nach einem Überblick über den aktuellen Wissensstand rund um HPLC-MS und die eingesetzten Instrumente werden alle relevanten Aspekte der Methodenentwicklung erläutert. Ein Kapitel zeigt Tipps und Tricks und enthält Anwenderberichte zu den Vorteilen und Tücken bei der Anwendung der Methode in der Praxis. Abgerundet werden die Darstellungen durch einen Ausblick auf zukünftige Entwicklungen renommierter Hersteller.

Advances in Chromatographic Techniques for Therapeutic Drug Monitoring

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Publisher : CRC Press
ISBN 13 : 1420067591
Total Pages : 475 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Advances in Chromatographic Techniques for Therapeutic Drug Monitoring by : Amitava Dasgupta

Download or read book Advances in Chromatographic Techniques for Therapeutic Drug Monitoring written by Amitava Dasgupta and published by CRC Press. This book was released on 2009-10-06 with total page 475 pages. Available in PDF, EPUB and Kindle. Book excerpt: For drugs with a narrow therapeutic index, therapeutic drug monitoring methods are essential for patient management. Although immunoassays are commercially available for many drugs and most laboratories use these assays for routine therapeutic monitoring, they have many limitations which hinder their efficacy. Providing practical guidelines for imp

High-Performance Liquid Chromatography

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Publisher : Elsevier
ISBN 13 : 1483262022
Total Pages : 343 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis High-Performance Liquid Chromatography by : Csaba Horváth

Download or read book High-Performance Liquid Chromatography written by Csaba Horváth and published by Elsevier. This book was released on 2013-10-22 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: High-Performance Liquid Chromatography: Advances and Perspectives, Volume 1 deals with the fundamental aspects of high-performance liquid chromatography, a technique used in chemical analysis. The publication provides accounts, presented by experts in the field, of a variety of topics in high-performance liquid chromatography. Each chapter covers interesting subjects such as the evolution of liquid chromatography; the use of bonded phases in high-performance chromatography; effects of ionization and complex formation on retention and selectivity in reversed-phase chromatography; and gradient elution. Chromatographers, chemists, and researchers in the field of chemical analysis will find this book a valuable reference material.

High Performance Liquid Chromatography

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 0471931152
Total Pages : 370 pages
Book Rating : 4.4/5 (719 download)

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Book Synopsis High Performance Liquid Chromatography by : Sandie Lindsay

Download or read book High Performance Liquid Chromatography written by Sandie Lindsay and published by John Wiley & Sons. This book was released on 1992-07-27 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: High performance liquid chromatography is the most powerful of all the chromatographic techniques, often achieving separations and analyses that would be difficult or impossible with other forms of chromatography. This study and training text examines the concepts and techniques used in this field. A selection of literature available from equipment manufacturers is included along with a brief review of some more specialized topics.

Practice of High Performance Liquid Chromatography

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Author :
Publisher : Springer
ISBN 13 : 9783642692260
Total Pages : 464 pages
Book Rating : 4.6/5 (922 download)

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Book Synopsis Practice of High Performance Liquid Chromatography by : Heinz Engelhardt

Download or read book Practice of High Performance Liquid Chromatography written by Heinz Engelhardt and published by Springer. This book was released on 2011-12-27 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: During its short 20 year history High Performance Liquid Chro matography (HPLC) has won itself a firm place amongst the instrumental methods of analysis. HPLC has caused a revolution in biological and pharmaceutical chemistry. Approximately two thirds of the publications on HPLC are concerned with problems from this area of life science. Biotechnology, where it is necessary to isolate substances from complicated mixtures, is likely to give further impetus to the dissemination of modern liquid chromatog raphy in columns, particularly on the preparative scale. This book presents, by means of examples, the application of HPLC to various fields, as well as fundamental discussions of chromatographic methods. The quality of the analytical result is decisively dependent on the qualities of the equipment employed (by Colin, Guiochon, and Martin). Especially the demands are discussed that are placed on the components of the instrument including those for data acquisition and processing. The section on "quantitative analy sis" (by ABhauer, Ullner) covers besides the principles also the problems of ensuring the quality of the data in detail. The basic problems arising by enlarging the sample size to preparative di mensions and the requirements put on the aparatus are discussed in the section on "preparative applications" (by Wehrli).

HPLC Method Development for Pharmaceuticals

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Author :
Publisher : Elsevier
ISBN 13 : 0080554199
Total Pages : 533 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis HPLC Method Development for Pharmaceuticals by : Satinder Ahuja

Download or read book HPLC Method Development for Pharmaceuticals written by Satinder Ahuja and published by Elsevier. This book was released on 2011-09-21 with total page 533 pages. Available in PDF, EPUB and Kindle. Book excerpt: High pressure, or high performance, liquid chromatography (HPLC) is the method of choice for checking purity of new drug candidates, monitoring changes during scale up or revision of synthetic procedures, evaluating new formulations, and running control/assurance of the final drug product. HPLC Method Development for Pharmaceuticals provides an extensive overview of modern HPLC method development that addresses these unique concerns. Includes a review and update of the current state of the art and science of HPLC, including theory, modes of HPLC, column chemistry, retention mechanisms, chiral separations, modern instrumentation (including ultrahigh-pressure systems), and sample preparation. Emphasis has been placed on implementation in a pharmaceutical setting and on providing a practical perspective. HPLC Method Development for Pharmaceuticals is intended to be particularly useful for both novice and experienced HPLC method development chemists in the pharmaceutical industry and for managers who are seeking to update their knowledge. - Covers the requirements for HPLC in a pharmaceutical setting including strategies for software and hardware validation to allow for use in a regulated laboratory - Provides an overview of the pharmaceutical development process (clinical phases, chemical and pharmaceutical development activities) - Discusses how HPLC is used in each phase of pharmaceutical development and how methods are developed to support activities in each phase

Principles and Applications of Clinical Mass Spectrometry

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Author :
Publisher : Elsevier
ISBN 13 : 0128160640
Total Pages : 218 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Principles and Applications of Clinical Mass Spectrometry by : Nader Rifai

Download or read book Principles and Applications of Clinical Mass Spectrometry written by Nader Rifai and published by Elsevier. This book was released on 2018-06-26 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles and Applications of Clinical Mass Spectrometry: Small Molecules, Peptides, and Pathogens is a concise resource for quick implementation of mass spectrometry methods in clinical laboratory work. Focusing on the practical use of these techniques, the first half of the book covers principles of chromatographic separations, principles and types of mass spectrometers, and sample preparation for analysis; the second half outlines the main applications of this technology within clinical laboratory settings, including determination of small molecules and peptides, as well as pathogen identification. A thorough yet succinct guide to using mass spectrometry technology in the clinical laboratory, Principles and Applications of Clinical Mass Spectrometry: Small Molecules, Peptides, and Pathogens is an essential resource for chemists, pharmaceutical and biotech researchers, certain government agencies, and standardization groups. - Provides concrete examples of the main applications of mass spectrometry technology - Describes current capabilities of the LC- and MS-based analytical methods - Details methods for successful analytical work in the field