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Heme Oxygenase In Biology And Medicine
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Book Synopsis Heme Oxygenase in Biology and Medicine by : Nader G. Abraham
Download or read book Heme Oxygenase in Biology and Medicine written by Nader G. Abraham and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heme oxygenase is rapidly taking its place as the centerpiece of multiple inter acting metabolic systems. Only 25 years ago heme oxygenase and its metabolic prod ucts appeared to be merely a simple metabolic system-one substrate, heme; one enzyme, heme oxygenase; and one set of products, iron to be recycled, and bilirubin and carbon monoxide to be disposed. From a group of about 25 people in 1974, as judged by attendance at various Gordon conferences, heme oxygenase has, in the year 2000, attracted working scientists-and clinicians I might add-by the hundreds and has produced referenced publications by the thousands. It is well-deserved attention. Heme oxygenase system is now similar to the metabolic networks surrounding glucose in those complex maps of glycolytic and non-glycolytic metabolic pathways, which we had to memorize as students. The relevance of heme oxygenase to regulatory biology was recognized many years ago, but the work conducted over the past five years has created a new wave of emphasis focusing on genetic manipulation to alter heme oxygenase gene expression, the regulatory actions of heme oxygenase products including carbon monoxide, and the significance of changes in the heme oxygenase system. The physiological and pathological relevance of heme oxygenase in the brain, heart, liver, bone marrow, organ transplant, lung and kidney, opens many areas of investigation in various dis ciplines. Advances in the pharmacology of bilirubin and its ability as an antioxidant have provided a new avenue in clinical research.
Book Synopsis Heme Oxygenase by : Nader G. Abraham
Download or read book Heme Oxygenase written by Nader G. Abraham and published by . This book was released on 2003 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Heme Oxygenase by : International Symposium on Heme Oxygenase. 2, 2002, Catania
Download or read book Heme Oxygenase written by International Symposium on Heme Oxygenase. 2, 2002, Catania and published by . This book was released on 2003 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Advances in Heme Oxygenase (Decyclizing) Research and Application: 2011 Edition by :
Download or read book Advances in Heme Oxygenase (Decyclizing) Research and Application: 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 48 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Heme Oxygenase (Decyclizing) Research and Application: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Heme Oxygenase (Decyclizing) in a concise format. The editors have built Advances in Heme Oxygenase (Decyclizing) Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Heme Oxygenase (Decyclizing) in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Heme Oxygenase (Decyclizing) Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Download or read book Heme Oxygenase written by Mahin D. Maines and published by CRC Press. This book was released on 1992-06-16 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: his book provides a comprehensive summary of data from basic research on characterization, regulation, and function of heme oxygenase in mammalian systems. The book also includes a major section that covers the currently used clinical methods to suppress neonatal jaundice with emphasis on the newly developed use of synthetic metalloporophyrins. This book will be welcomed by researchers and students in pharmacology, biochemistry, pharmacy, neonatology, hematology, internal medicine, and endocrinology.
Book Synopsis Heme Oxygenase by : Leo E. Otterbein
Download or read book Heme Oxygenase written by Leo E. Otterbein and published by Nova Publishers. This book was released on 2005 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heme oxygenase is an enzyme which breaks down heme, the iron-containing oxygen-carrying constituent of the red blood cells. Heme must be synthesised and degraded within an individual nucleated cell, as heme is essential for the maintenance of cellular homeostasis by sensing or using oxygen. Physiological heme degradation is catalysed by the two functional isozymes of heme oxygenase, heme oxygenase-1 (HO-1) and HO-2, yielding CO, iron, and biliverdin IX N. Heme oxygenase-1 (HO-1), has potent anti-inflammatory, anti-oxidant and anti-proliferative effects, is up-regulated by multiple stimuli and provides protection against oxidative stress. HO-1 also plays an important role in the regulation of cardiovascular function and is involved in many other diseases such as sickle cell disease. This new book brings together leading research from around the world in this field.
Book Synopsis Heme Biology: The Secret Life Of Heme In Regulating Diverse Biological Processes by : Li Zhang
Download or read book Heme Biology: The Secret Life Of Heme In Regulating Diverse Biological Processes written by Li Zhang and published by World Scientific. This book was released on 2011-07-19 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: This invaluable book provides the first description of the diverse and fascinating functions of heme in life processes for a broad audience. It begins with an introduction to the intricate chemical properties of heme and the history of early observations of human diseases associated with heme. It then proceeds to describe the versatile roles of heme in controlling diverse molecular and cellular processes germane to human life and disease processes. Finally, an up-to-date review of human diseases associated with heme synthesis and application of heme synthesis in photodynamic therapy in cancer treatment is presented.Heme biology is unified and logical in presentation. It is well suited for students and professionals in life sciences who wish to comprehend the fascinating biology of heme and its usefulness in health and diseases. It may also be used as a reference book for advanced readers and researchers who are interested in heme biology. The explanations in the book are detailed enough to capture the interest of the curious reader, and complete enough to provide the necessary information for researchers to have an in-depth molecular understanding of heme biology and further their studies in this fascinating realm.
Book Synopsis Advances in Heme Oxygenase (Decyclizing) Research and Application: 2012 Edition by :
Download or read book Advances in Heme Oxygenase (Decyclizing) Research and Application: 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 97 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Heme Oxygenase (Decyclizing) Research and Application / 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Heme Oxygenase (Decyclizing) in a concise format. The editors have built Advances in Heme Oxygenase (Decyclizing) Research and Application / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Heme Oxygenase (Decyclizing) in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Heme Oxygenase (Decyclizing) Research and Application / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Book Synopsis Heme Oxygenase (HO)-1 as an Immunoregulator in Health and Disease by : Elias A Lianos
Download or read book Heme Oxygenase (HO)-1 as an Immunoregulator in Health and Disease written by Elias A Lianos and published by Mdpi AG. This book was released on 2023-07-17 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heme oxygenase (HO)-1 is a well-known, cytoprotective enzyme, responsible for the enzymatic conversion of heme into the anti-apoptotic and antioxidant by-products, biliverdin, bilirubin and carbon monoxide. However, HO-1 also regulates responses via mechanisms that are independent of the generation of heme degradation products. The current Special Issue contains research and review articles on the effect of heme oxygenase on immune-related cellular and physiological cascades and functions including effects on innate immunity, adaptive immunity, inflammation and complement activation. A description of the role of HO-1 in immune regulation directly or via its by-products is depicted on various forms of infection, viral and bacterial, immune-mediated injury such as renal injury, allergic airway inflammation, cancer and metabolism. Thus, the current Special Issue aims to serve as a detailed, analytical and up-to-date guide of the recent advances on the immunomodulatory properties of HO-1.
Book Synopsis Oxygen Homeostasis and Its Dynamics by : Yuzuru Ishimura
Download or read book Oxygen Homeostasis and Its Dynamics written by Yuzuru Ishimura and published by Springer. This book was released on 1998 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first volume in a projected series contains the proceedings of the first of the Keio University International Symposia for Life Sciences and Medicine under the sponsorship of the Keio University Medical Science Fund. As stated in the address by the President of Keio University at the opening of the 1996 symposium, the fund of Dr. Mitsunada Sakaguchi. The Keio was established by the generous donation University International Symposia for Life Sciences and Medicine constitute one of the core activities of the fund. The objective is to contribute to the international community by developing human resources, promoting scientific knowledge, and encouraging mutual exchange. Every year, the Executive Committee of the Interna tional Symposia for Life Sciences and Medicine selects the most interesting topics for the symposium from applications received in response to a call for papers to the Keio medical community. The publication of these proceedings is intended to publicize and distribute information arising from the lively discussions of the most exciting and current issues during the symposium. Weare grateful to Dr. Mitsunada Sakaguchi, who made the symposium possible, the members of the program committee, and the office staff whose support guaran teed the success of the symposium. Finally, we thank Springer-Verlag, Tokyo, for their assistance in publishing this work. Akimichi Kaneko, M. D. , Ph. D.
Author :United States. Public Health Service. Office of the Surgeon General Publisher : ISBN 13 : Total Pages :728 pages Book Rating :4.:/5 (318 download)
Book Synopsis How Tobacco Smoke Causes Disease by : United States. Public Health Service. Office of the Surgeon General
Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Book Synopsis Oxidants, Antioxidants, and Impact of the Oxidative Status in Male Reproduction by : Ralf Henkel
Download or read book Oxidants, Antioxidants, and Impact of the Oxidative Status in Male Reproduction written by Ralf Henkel and published by Academic Press. This book was released on 2018-08-23 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oxidants, Antioxidants and Impact of the Oxidative Status in Male Reproduction is an essential reference for fertility practitioners and research and laboratory professionals interested in learning about the role of reactive oxygen species in sperm physiology and pathology. The book focuses on unravelling the pathophysiology of oxidative stress mediated male infertility, recruiting top researchers and clinicians to contribute chapters. This collection of expertise delves into the physico-chemical aspects of oxidative stress, including a new focus on reductive stress. Furthermore, the inclusion of clinical techniques to determine oxidative stress and the OMICS of reductive oxidative stress are also included. This is a must-have reference in the area of oxidative stress and male reproductive function. Offers comprehensive information on oxidative stress and its role in male reproduction, including new therapeutic approaches Deals with current approaches to oxidative stress using OMICS platform“/li> Designed for fertility practitioners, reproductive researchers, and laboratory professionals interested in learning about the role of reactive oxygen species in sperm physiology and pathology
Book Synopsis Handbook of Cell Signaling by : Ralph A. Bradshaw
Download or read book Handbook of Cell Signaling written by Ralph A. Bradshaw and published by Academic Press. This book was released on 2009-11-03 with total page 3188 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Cell Signaling, Three-Volume Set, 2e, is a comprehensive work covering all aspects of intracellular signal processing, including extra/intracellular membrane receptors, signal transduction, gene expression/translation, and cellular/organotypic signal responses. The second edition is an up-to-date, expanded reference with each section edited by a recognized expert in the field. Tabular and well illustrated, the Handbook will serve as an in-depth reference for this complex and evolving field. Handbook of Cell Signaling, 2/e will appeal to a broad, cross-disciplinary audience interested in the structure, biochemistry, molecular biology and pathology of cellular effectors. Contains over 350 chapters of comprehensive coverage on cell signaling Includes discussion on topics from ligand/receptor interactions to organ/organism responses Provides user-friendly, well-illustrated, reputable content by experts in the field
Book Synopsis Experimental Biology and Medicine by :
Download or read book Experimental Biology and Medicine written by and published by . This book was released on 2003 with total page 846 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Inducible Enzymes in the Inflammatory Response by : D. A. Willoughby
Download or read book Inducible Enzymes in the Inflammatory Response written by D. A. Willoughby and published by Springer Science & Business Media. This book was released on 1999 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book brings together overviews by leading researchers in the field of the current status of knowledge of COX, NOS and HO in inflammation. These overviews cover a series of new concepts in the mechanism of inflammation. Topics include inducible enzyme involvement in inflammatory processes including the role in vascular permeability, leukocyte migration, granuloma formation, angiogenesis, neuroinflammation and algesia. New findings from transgenic animal models are reviewed. Other chapters address the importance of these enzymes in inflammatory disease states including rheumatoid arthritis, atherosclerosis and multiple sclerosis. The possibility of selective inhibitors or inducers of COX, NOS and HO, and their use in the clinic is discussed. The subject matter of this book is of interest to rheumatologists, pathologists, pharmacologists, neuroscientists and anyone with an academic interest in the mechanisms of inflammation.
Book Synopsis Flavin-Dependent Enzymes: Mechanisms, Structures and Applications by :
Download or read book Flavin-Dependent Enzymes: Mechanisms, Structures and Applications written by and published by Academic Press. This book was released on 2020-09-21 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Enzymes, Volume 47, highlights new advances in the field, with this new volume presenting interesting chapters on The Multipurpose Family of Oxidases, Vanillyl alcohol oxidase, Choline oxidases, Aryl alcohol oxidase, D- and L-amino acid oxidases, Sugar oxidases, Phenolic Compounds hydroxylases, Baeyer-Villiger Monooxygenases, Flavin-dependent halogenases, Flavin-dependent dehalogenases, Styrene Monooxygenases, Bacterial luciferases, Cellobiose Dehydrogenases, Prenylated flavoenzymes, Ene-reductases, Flavoenzymes in Biocatalysis. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in The Enzymes series
Book Synopsis Nitric Oxide Synthase: Characterization and Functional Analysis by :
Download or read book Nitric Oxide Synthase: Characterization and Functional Analysis written by and published by Academic Press. This book was released on 1996-09-18 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although the function of nitric oxide in a regulatory capacity in the central and peripheral nervous system is widely recognized, the full scope of its actions and its interrelationships with other classes of regulatory molecules is just beginning to be comprehended. This volume contains a number of sophisticated and advanced methods essential for exploring the activity of nitric oxide in the brain. It will be a valuable tool for the established investigator and for those just entering the field. Comprehensive protocols included for detection of NO and related compounds by chemical, immunohistochemical, and in situ hybridization techniques Newly developed methods for the purification of neuronal and endothelial NO synthase, production of monoclonal antibodies to NO synthase, molecular cloning and expression of NO synthesis, and control of NO synthase gene expression Assessment of NO-mediated functions in neurons, central nervous system, cerebral circulation, synaptic transmission, and vascular tone Calcium imaging by confocal microscopy, evaluation of the effect of NO on iron metabolism, and detection of heme oxygenase-1 and -2 message level and distribution
