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Handbook Of Chiral Chemicals Second Edition
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Book Synopsis Handbook Of Chiral Chemicals by : David John Ager
Download or read book Handbook Of Chiral Chemicals written by David John Ager and published by CRC Press. This book was released on 1999-01-04 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: Describes the problems associated with large, commercial-scale syntheses of chiral molecules and the relatively small number of reactions that can be used to achieve these syntheses. The book discusses commercially viable and still-developing methods of compound manufacture, and reviews the best-selling chiral compounds as of 1996.
Book Synopsis Handbook of Chiral Chemicals by : David Ager
Download or read book Handbook of Chiral Chemicals written by David Ager and published by CRC Press. This book was released on 2005-10-21 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: As pharmaceutical companies look to develop single enantiomers as drug candidates, chemists are increasingly faced with the problems associated with this subclass of organic synthesis. "The Handbook of Chiral Chemicals, Second Edition" highlights the problems associated with the production of chiral compounds on a commercial scale. The handbook fir
Book Synopsis Handbook for Chemical Process Research and Development, Second Edition by : Wenyi Zhao
Download or read book Handbook for Chemical Process Research and Development, Second Edition written by Wenyi Zhao and published by CRC Press. This book was released on 2023-03-21 with total page 938 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fully updated second edition reflects the significant changes in process chemistry since the first edition and includes more common process issues such as safety, cost, robustness, and environmental impact. Some areas have made notable progress such as process safety, stereochemistry, new reagents and reagent surrogates. Forty years ago there were few process research and development activities in the pharmaceutical industry, partly due to the simplicity of drug molecules. With increasing structural complexity especially the introduction of chiral centers into drug molecules and stricter regulations, process R&D has become one of the critical departments for pharmaceutical companies. Features: This unique volume now in its second edition is designed to provide readers with an unprecedented strategy and approach which will help chemists and graduate students develop chemical processes in an efficient manner. Promotes an industrial mindset concerning safety and commercial viability when developing methods. The author discusses development strategies with case studies and experimental procedures. Focuses on mechanism-guided process development which provides readers with practical strategies and approaches. Addresses more common process issues such as safety, cost, robustness, and environmental impact. This book provides a new direction for scientists, researchers, and students in materials science and polymer chemistry who seek to better understand the chemistry behind conducting polymers and improve their performance for use in advanced energy applications.
Book Synopsis Enantioselective Chemical Synthesis by : Elias J. Corey
Download or read book Enantioselective Chemical Synthesis written by Elias J. Corey and published by Elsevier. This book was released on 2013-10-23 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by world-renowned and best-selling experts, Nobel Laureate E. J. Corey and Laszlo Kurti, Enantioselective Chemical Synthesis offers an authoritative and comprehensive overview of the field's progress; the processes and tools for key formations; future development for complex, stereocontrolled (enantiomeric or diastereoisomeric) molecules; and valuable examples of multi-step syntheses. Utilizing a color-coded scheme to illustrate chemical transformations, Enantioselective Chemical Synthesis provides clear explanation and guidance through vital asymmetrical syntheses and insight into the next steps for the field. Researchers, professionals, and academics will benefit from this valuable, thorough, and unique resource. - In Part I, the authors present clearly, comprehensively and concisely the most useful enantioselective processes available to synthetic chemists. - Part II provides an extensive discussion of the most logical ways to apply these new enantioselective methods to the planning of syntheses of stereochemically complex molecules. This hitherto neglected area is essential for the advancement of enantioselective synthesis to a more rational and powerful level. - Part III describes in detail many reaction sequences which have been used successfully for the construction of a wide variety of complex target molecules - Clearly explains stereochemical synthesis in theory and practice - Provides a handy tool box for scientists wishing to understand and apply chiral chemical synthesis - Describes almost 50 real life examples of asymmetric synthesis in practice and examines how the chiral centers were introduced at key synthetic stages
Book Synopsis Handbook of Reagents for Organic Synthesis: Chiral reagents for asymmetric synthesis by : Leo A. Paquette
Download or read book Handbook of Reagents for Organic Synthesis: Chiral reagents for asymmetric synthesis written by Leo A. Paquette and published by . This book was released on 2003 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Practical Process Research and Development by : Neal G. Anderson
Download or read book Practical Process Research and Development written by Neal G. Anderson and published by Academic Press. This book was released on 2012-05-23 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designed to provide a comprehensive, step-by-step approach to organic process research and development in the pharmaceutical, fine chemical, and agricultural chemical industries, this book describes the steps taken, following synthesis and evaluation, to bring key compounds to market in a cost-effective manner. It describes hands-on, step-by-step, approaches to solving process development problems, including route, reagent, and solvent selection; optimising catalytic reactions; chiral syntheses; and "green chemistry." Second Edition highlights:• Reflects the current thinking in chemical process R&D for small molecules• Retains similar structure and orientation to the first edition. • Contains approx. 85% new material• Primarily new examples (work-up and prospective considerations for pilot plant and manufacturing scale-up)• Some new/expanded topics (e.g. green chemistry, genotoxins, enzymatic processes)• Replaces the first edition, although the first edition contains useful older examples that readers may refer to - Provides insights into generating rugged, practical, cost-effective processes for the chemical preparation of "small molecules" - Breaks down process optimization into route, reagent and solvent selection, development of reaction conditions, workup, crystallizations and more - Presents guidelines for implementing and troubleshooting processes
Book Synopsis Handbook of Preformulation by : Sarfaraz K. Niazi
Download or read book Handbook of Preformulation written by Sarfaraz K. Niazi and published by CRC Press. This book was released on 2019-03-22 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: Preformulation studies are the physical, chemical, and biological studies needed to characterize a drug substance for enabling the proper design of a drug product, whereas the effectiveness of a drug product is determined during the formulation studies phase. Though the two disciplines overlap in practice, each is a significantly distinct phase of new drug development. Entirely focused on preformulation principles, this fully revised and updated Handbook of Preformulation: Chemical, Biological, and Botanical Drugs, Second Edition provides detailed descriptions of preformulation methodologies, gives a state-of-the-art description of each technique, and lists the currently available tools useful in providing a comprehensive characterization of a new drug entity. Features: Addresses the preformulation studies of three different types of new active entities - chemical, biological, and botanical, which is the latest established class of active ingredient classified by the FDA Illustrates the activities comprised in preformulation studies and establishes a method of tasking for drug development projects Includes extensive flow charts for characterization decision making Gives extensive theoretical treatment of principles important for testing dissolution, solubility, stability, and solid state characterization Includes over 50% new material
Book Synopsis Practical Process Research and Development by : Neal G. Anderson
Download or read book Practical Process Research and Development written by Neal G. Anderson and published by Academic Press. This book was released on 2012-04-09 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designed to provide a comprehensive, step-by-step approach to organic process research and development in the pharmaceutical, fine chemical, and agricultural chemical industries, this book describes the steps taken, following synthesis and evaluation, to bring key compounds to market in a cost-effective manner. It describes hands-on, step-by-step, approaches to solving process development problems, including route, reagent, and solvent selection; optimising catalytic reactions; chiral syntheses; and "green chemistry." Second Edition highlights: . Reflects the current thinking in chemical process R&D for small molecules . Retains similar structure and orientation to the first edition. . Contains approx. 85% new material . Primarily new examples (work-up and prospective considerations for pilot plant and manufacturing scale-up) . Some new/expanded topics (e.g. green chemistry, genotoxins, enzymatic processes) . Replaces the first edition, although the first edition contains useful older examples that readers may refer to Provides insights into generating rugged, practical, cost-effective processes for the chemical preparation of "small molecules" Breaks down process optimization into route, reagent and solvent selection, development of reaction conditions, workup, crystallizations and more Presents guidelines for implementing and troubleshooting processes
Book Synopsis Handbook of Asymmetric Heterogeneous Catalysis by : Kuiling Ding
Download or read book Handbook of Asymmetric Heterogeneous Catalysis written by Kuiling Ding and published by John Wiley & Sons. This book was released on 2008-10-20 with total page 467 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this most up-to-date handbook each chapter contains a general introduction, followed by the principles of the immobilization and, finally, applications. In this way, it covers the most important approaches currently employed for the heterogenization of chiral catalysts, including data tables, applications, reaction types and literature citations. For chemists in both academia and industry as well as those working in the fine chemical and pharmaceutical industry.
Download or read book Chemical Engineering Progress written by and published by . This book was released on 2006 with total page 940 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Catalysis of Organic Reactions by : Stephen R. Schmidt
Download or read book Catalysis of Organic Reactions written by Stephen R. Schmidt and published by CRC Press. This book was released on 2006-12-07 with total page 547 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bringing together academic, industrial, and governmental researchers and developers, Catalysis of Organic Reactions comprises 57 peer-reviewed papers on the latest scientific developments in applied catalysis for organic reactions. The volume describes the use of both heterogeneous and homogeneous catalyst systems and includes original resea
Download or read book Comprehensive Chirality written by and published by Newnes. This book was released on 2012-12-31 with total page 5635 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although many books exist on the subject of chiral chemistry, they only briefly cover chiral synthesis and analysis as a minor part of a larger work, to date there are none that pull together the background information and latest advances in one comprehensive reference work. Comprehensive Chirality provides a complete overview of the field, and includes chiral research relevant to synthesis, analytic chemistry, catalysis, and pharmaceuticals. The individual chapters in each of the 9 volumes provide an in depth review and collection of references on definition, technology, applications and a guide/links to the related literature. Whether in an Academic or Corporate setting, these chapters will form an invaluable resource for advanced students/researchers new to an area and those who need further background or answers to a particular problem, particularly in the development of drugs. Chirality research today is a central theme in chemistry and biology and is growing in importance across a number of disciplinary boundaries. These studies do not always share a unique identifying factor or subject themselves to clear and concise definitions. This work unites the different areas of research and allows anyone working or researching in chiral chemistry to navigate through the most essential concepts with ease, saving them time and vastly improving their understanding. The field of chirality counts several journals that are directly and indirectly concerned with the field. There is no reference work that encompasses the entire field and unites the different areas of research through deep foundational reviews. Comprehensive Chirality fills this vacuum, and can be considered the definitive work. It will help users apply context to the diverse journal literature offering and aid them in identifying areas for further research and/or for solving problems. Chief Editors, Hisashi Yamamoto (University of Chicago) and Erick Carreira (ETH Zürich) have assembled an impressive, world-class team of Volume Editors and Contributing Authors. Each chapter has been painstakingly reviewed and checked for consistent high quality. The result is an authoritative overview which ties the literature together and provides the user with a reliable background information and citation resource.
Book Synopsis Comprehensive Organic Transformations, 4 Volume Set by : Richard C. Larock
Download or read book Comprehensive Organic Transformations, 4 Volume Set written by Richard C. Larock and published by John Wiley & Sons. This book was released on 2018-03-20 with total page 3955 pages. Available in PDF, EPUB and Kindle. Book excerpt: PROSE Award Finalist 2019 - Multivolume Reference/Science Association of American Publishers Award for Professional and Scholarly Excellence This greatly-expanded new edition of a best-selling guide offers an encyclopedic and systematic collection of useful synthetic methodology, including tens of thousands of reactions and synthetic transformations. Covers and cross references so practicing chemists can easily navigate through the book’s comprehensive coverage of reagents and reactions Updates and expands a best-selling guide through the year 2011 "...the book is undoubtedly still of great value and every chemist working in the area of synthesis should have it within reach in the laboratory." —Angewandte Chemie review of the 2nd edition "...an indispensable reference work for designing and carrying out modern organic chemical synthesis.... It is amazing that so much information is contained in a single volume that is arranged in a logical and easy to use fashion." —Analytical Biochemistry review of the 2nd edition
Book Synopsis Thin Layer Chromatography in Chiral Separations and Analysis by : Teresa Kowalska
Download or read book Thin Layer Chromatography in Chiral Separations and Analysis written by Teresa Kowalska and published by CRC Press. This book was released on 2007-06-22 with total page 437 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thin layer chromatography (TLC) is well suited for performing enantioseparations for research as well as larger-scale applications. A fast, inexpensive, and versatile separation technique, there are many practical considerations that contribute to its effectiveness. Thin Layer Chromatography in Chiral Separations and Analysis is the first bo
Book Synopsis Ullmann's Fine Chemicals by : Wiley-VCH
Download or read book Ullmann's Fine Chemicals written by Wiley-VCH and published by John Wiley & Sons. This book was released on 2014-01-07 with total page 1905 pages. Available in PDF, EPUB and Kindle. Book excerpt: A compilation of 76 articles from the ULLMANN's Encyclopedia of Industrial Chemistry, this three-volume handbook contains a wealth of information on the production and industrial use of more than 2,000 of the most important fine chemicals, from "Alcohols" to "Urea Derivatives". Chemical and physical characteristics, production processes and production figures, main uses, toxicology and safety information are all found here in one single resource.
Book Synopsis Hansen Solubility Parameters by : Charles M. Hansen
Download or read book Hansen Solubility Parameters written by Charles M. Hansen and published by CRC Press. This book was released on 2007-06-15 with total page 546 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hansen solubility parameters (HSPs) are used to predict molecular affinities, solubility, and solubility-related phenomena. Revised and updated throughout, Hansen Solubility Parameters: A User's Handbook, Second Edition features the three Hansen solubility parameters for over 1200 chemicals and correlations for over 400 materials including p
Book Synopsis Differentiation of Chiral Compounds Using NMR Spectroscopy by : Thomas J. Wenzel
Download or read book Differentiation of Chiral Compounds Using NMR Spectroscopy written by Thomas J. Wenzel and published by John Wiley & Sons. This book was released on 2018-06-01 with total page 1303 pages. Available in PDF, EPUB and Kindle. Book excerpt: An updated guide to the most current information available for determining how to use NMR spectroscopy to differentiate chiral compounds Differentiation of Chiral Compounds Using NMR Spectroscopy offers a thoroughly revised second edition to the essential volume that puts the focus on the chiral systems that are commercially available and have been widely vetted for use in NMR spectroscopy. The text covers a broad range of reagents that make it possible to determine the enantiomeric purity and assign the absolute configuration of many classes of compounds. Comprehensive in scope, the text describes the chiral NMR differentiating agents as derivatizing agents, solvating agents, metal-based reagents and liquid crystals and gels, and explains the range and types of compounds for which they can be used for analysis. New to this edition are the most recent findings in the field as well as the development of advanced NMR measurement techniques that allow for the simplification of complex spectra resulting in more readily identified enantiodifferentiation. This important resource: Includes the most recent coverage of a large range of compounds that can be analyzed using chiral NMR reagents Explores the use of chiral NMR reagents and explains their relationship to the stereochemistry of the analyzed molecules Offers the essential information needed to help decide which method is the best NMR method to apply to a class or molecules Contains experimental strategies for using the reagents that are likely to improve the quality of the results Differentiation of Chiral Compounds Using NMR Spectroscopy is a comprehensive guide designed for investigators planning to use NMR spectroscopy to determine enantiomeric purity or assign the absolute configuration of a compound.
